Butyl Glucoside

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  • Identifiers

    CAS number
    5391-18-4

    Molecular formula
    C10H20O6

    SMILES
    CCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 54.1%
    Sweet 38.8%
    Alcoholic 32.4%
    Fruity 29.12%
    Caramellic 27.64%
    Milky 22.51%
    Vanilla 21.7%
    Buttery 21.61%
    Oily 21.04%
    Malty 19.9%

     

    Flavor
    Sweet 74.21%
    Odorless 43.18%
    Bitter 36.45%
    Sweet-like 29.1%
    Fatty 25.3%
    Cauliflower 24.42%
    Very slight 23.37%
    Caramel 23.13%
    Alcoholic 22.48%
    Mentholic 22.37%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.9

    pKa est.
    5.84 (weak acid)

    Molecular weight
    236.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    633°C

    Flash point

    • 185.83 ˚C est.

  • Synonyms

    • Butyl beta-D-glucopyranoside
    • 5391-18-4
    • butyl glucoside
    • Beta-D-Glucopyranoside, Butyl
    • Butyl .beta.-D-glucopyranoside
    • .beta.-D-Glucopyranoside, butyl
    • EINECS 226-387-8
    • 20TBL42142
    • DTXSID801021370
    • N-BUTYL-BETA-D-GLUCOPYRANOSIDE
    • N-BUTYL-.BETA.-D-GLUCOPYRANOSIDE
    • BUTYL .BETA.-D-GLUCOPYRANOSIDE, (-)-
    • RefChem:571735
    • BUTYL GLUCOSIDE [INCI]
    • DTXCID901506414
    • BUTYL BETA-D-GLUCOPYRANOSIDE, (-)-
    • 226-387-8
    • Butyl b-D-glucopyranoside
    • BUTYL-BETA-D-GLUCOPYRANOSIDE
    • (2R,3R,4S,5S,6R)-2-butoxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • n-butyl beta-D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-butoxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
    • (2R,3R,4S,5S,6R)-2-Butoxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • SCHEMBL2447680
    • CHEMBL3326716
    • UNII-20TBL42142
    • MFCD08704049
    • MB08363
    • BS-28551
    • NS00081027
    • H57525
    • 391B184
    • Q27894788
    • 5391-18-4

  • Applications

    Butyl Glucoside, CAS 5391-18-4, is a mild, biodegradable nonionic surfactant widely used in cosmetics and personal care as a gentle cleanser, emulsifier, and solubilizer for fragrances and essential oils; it also serves as a solvent and humectant in formulations and is commonly used in household and industrial cleaners to improve wetting and foaming. In coatings and inks, it is employed as a surfactant additive to enhance dispersion and surface wetting, and in fragrance applications as a solubilizer for fragrance oils, with potential use as a processing aid in polymer and plastics formulations, all subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 18.24
    methanol 122.75
    isopropanol 5.22
    water 253.75
    ethyl acetate 3.64
    n-propanol 7.74
    acetone 2.56
    n-butanol 6.37
    acetonitrile 2.18
    DMF 120.76
    toluene 0.81
    isobutanol 4.45
    1,4-dioxane 14.64
    methyl acetate 2.68
    THF 12.93
    2-butanone 1.93
    n-pentanol 3.13
    sec-butanol 3.89
    n-hexane 0.17
    ethylene glycol 276.52
    NMP 147.88
    cyclohexane 1.59
    DMSO 662.74
    n-butyl acetate 4.14
    n-octanol 4.46
    chloroform 3.27
    n-propyl acetate 2.66
    acetic acid 222.23
    dichloromethane 3.88
    cyclohexanone 15.63
    propylene glycol 97.47
    isopropyl acetate 3.7
    DMAc 92.92
    2-ethoxyethanol 50.4
    isopentanol 6.73
    n-heptane 0.68
    ethyl formate 7.76
    1,2-dichloroethane 4.1
    n-hexanol 6.13
    2-methoxyethanol 150.06
    isobutyl acetate 1.96
    tetrachloromethane 1.42
    n-pentyl acetate 3.89
    transcutol 126.83
    n-heptanol 6.22
    ethylbenzene 0.95
    MIBK 3.7
    2-propoxyethanol 38.89
    tert-butanol 10.67
    MTBE 1.9
    2-butoxyethanol 26.09
    propionic acid 35.84
    o-xylene 2.15
    formic acid 949.03
    diethyl ether 1.02
    m-xylene 1.7
    p-xylene 1.17
    chlorobenzene 1.61
    dimethyl carbonate 10.51
    n-octane 0.4
    formamide 577.32
    cyclopentanone 17.12
    2-pentanone 2.11
    anisole 2.95
    cyclopentyl methyl ether 6.59
    gamma-butyrolactone 44.28
    1-methoxy-2-propanol 61.9
    pyridine 6.93
    3-pentanone 2.53
    furfural 66.07
    n-dodecane 0.34
    diethylene glycol 144.3
    diisopropyl ether 0.94
    tert-amyl alcohol 8.58
    acetylacetone 13.5
    n-hexadecane 0.38
    acetophenone 8.14
    methyl propionate 6.77
    isopentyl acetate 5.03
    trichloroethylene 8.59
    n-nonanol 4.38
    cyclohexanol 14.66
    benzyl alcohol 11.23
    2-ethylhexanol 4.2
    isooctanol 5.48
    dipropyl ether 2.18
    1,2-dichlorobenzene 3.31
    ethyl lactate 16.77
    propylene carbonate 26.29
    n-methylformamide 80.27
    2-pentanol 3.18
    n-pentane 0.28
    1-propoxy-2-propanol 21.42
    1-methoxy-2-propyl acetate 14.42
    2-(2-methoxypropoxy) propanol 31.49
    mesitylene 2.05
    ε-caprolactone 25.26
    p-cymene 2.3
    epichlorohydrin 17.75
    1,1,1-trichloroethane 1.76
    2-aminoethanol 150.65
    morpholine-4-carbaldehyde 121.77
    sulfolane 219.57
    2,2,4-trimethylpentane 0.4
    2-methyltetrahydrofuran 5.82
    n-hexyl acetate 5.6
    isooctane 0.27
    2-(2-butoxyethoxy)ethanol 44.17
    sec-butyl acetate 2.14
    tert-butyl acetate 6.69
    decalin 0.67
    glycerin 367.7
    diglyme 66.96
    acrylic acid 81.93
    isopropyl myristate 2.63
    n-butyric acid 32.6
    acetyl acetate 8.62
    di(2-ethylhexyl) phthalate 8.11
    ethyl propionate 2.89
    nitromethane 104.95
    1,2-diethoxyethane 6.56
    benzonitrile 5.43
    trioctyl phosphate 6.51
    1-bromopropane 0.81
    gamma-valerolactone 63.86
    n-decanol 3.43
    triethyl phosphate 6.84
    4-methyl-2-pentanol 3.79
    propionitrile 1.65
    vinylene carbonate 27.14
    1,1,2-trichlorotrifluoroethane 132.78
    DMS 10.17
    cumene 1.27
    2-octanol 3.1
    2-hexanone 1.7
    octyl acetate 3.77
    limonene 3.29
    1,2-dimethoxyethane 23.47
    ethyl orthosilicate 5.72
    tributyl phosphate 6.27
    diacetone alcohol 26.96
    N,N-dimethylaniline 4.95
    acrylonitrile 5.44
    aniline 5.18
    1,3-propanediol 134.46
    bromobenzene 1.27
    dibromomethane 2.18
    1,1,2,2-tetrachloroethane 9.61
    2-methyl-cyclohexyl acetate 6.87
    tetrabutyl urea 9.84
    diisobutyl methanol 3.99
    2-phenylethanol 11.59
    styrene 0.92
    dioctyl adipate 7.38
    dimethyl sulfate 45.24
    ethyl butyrate 3.99
    methyl lactate 45.77
    butyl lactate 13.73
    diethyl carbonate 3.89
    propanediol butyl ether 39.81
    triethyl orthoformate 5.31
    p-tert-butyltoluene 2.45
    methyl 4-tert-butylbenzoate 18.15
    morpholine 22.81
    tert-butylamine 3.49
    n-dodecanol 2.78
    dimethoxymethane 20.02
    ethylene carbonate 19.4
    cyrene 62.97
    2-ethoxyethyl acetate 8.51
    2-ethylhexyl acetate 3.55
    1,2,4-trichlorobenzene 5.34
    4-methylpyridine 3.69
    dibutyl ether 1.63
    2,6-dimethyl-4-heptanol 3.99
    DEF 17.68
    dimethyl isosorbide 50.34
    tetrachloroethylene 10.96
    eugenol 22.13
    triacetin 15.41
    span 80 32.36
    1,4-butanediol 43.07
    1,1-dichloroethane 0.9
    2-methyl-1-pentanol 4.15
    methyl formate 44.33
    2-methyl-1-butanol 5.33
    n-decane 0.45
    butyronitrile 1.56
    3,7-dimethyl-1-octanol 4.96
    1-chlorooctane 1.18
    1-chlorotetradecane 0.73
    n-nonane 0.41
    undecane 0.38
    tert-butylcyclohexane 0.4
    cyclooctane 0.92
    cyclopentanol 13.94
    tetrahydropyran 4.44
    tert-amyl methyl ether 2.74
    2,5,8-trioxanonane 60.25
    1-hexene 0.28
    2-isopropoxyethanol 20.22
    2,2,2-trifluoroethanol 149.82
    methyl butyrate 4.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction