Bromocyclopentane

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  • Identifiers

    CAS number
    137-43-9

    Molecular formula
    C5H9Br

    SMILES
    C1CCC(C1)Br

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Floral 33.28%
    Citrus 32.58%
    Woody 32.04%
    Clean 29.72%
    Fresh 29.55%
    Animal 28.0%
    Musk 27.32%
    Dry 27.27%
    Mint 25.21%
    Green 24.62%

     

    Flavor
    Ammoniacal 36.87%
    Animal 33.7%
    Sweet 27.89%
    Egg 26.56%
    Alkaline 26.23%
    Fishy 25.26%
    Amine 23.75%
    Sulfurous 23.69%
    Shrimp 23.19%
    Penetrating 21.42%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    5.36 (weak acid)

    Molecular weight
    149.03 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    136°C

    Flash point

    • 39.6 ˚C est.

  • Synonyms

    • Bromocyclopentane
    • CYCLOPENTYL BROMIDE
    • Cyclopentane, bromo-
    • NSC 1110
    • EINECS 205-294-6
    • AI3-23448
    • DTXSID9059670
    • EC 205-294-6
    • RefChem:121572
    • DTXCID1034393
    • 205-294-6
    • BRTFVKHPEHKBQF-UHFFFAOYSA-N
    • InChI=1/C5H9Br/c6-5-3-1-2-4-5/h5H,1-4H
    • 137-43-9
    • cyclopentylbromide
    • 1-bromocyclopentane
    • bromo-cyclopentane
    • MFCD00001359
    • QP65Z83BNY
    • NSC-1110
    • Cyclopentyl Bromide; NSC 1110
    • bromocyclopentan
    • cylopentylbromide
    • bromo cyclopentane
    • NSC1110
    • cyclopentyl-bromide
    • 4-bromocyclopentane
    • 1-bromo-cyclopentane
    • UNII-QP65Z83BNY
    • Bromocyclopentane, >=98%
    • SCHEMBL70317
    • SCHEMBL193236
    • SCHEMBL1000576
    • SCHEMBL1411697
    • SCHEMBL2291357
    • STR00677
    • MSK160865
    • SBB040823
    • AKOS000121495
    • FC34696
    • B1006
    • NS00004845
    • ST50214403
    • EN300-16489
    • G77213
    • F021866
    • Q15634264
    • F2190-0180
    • 137-43-9

  • Applications

    Bromocyclopentane (CAS 137-43-9) is primarily used as an organic synthesis intermediate, providing a cyclopentyl moiety that can be installed into a range of target molecules via nucleophilic substitution and related transformations. It serves as a building block for the preparation of other brominated and cyclopentyl-containing compounds, enabling synthetic routes in pharmaceutical, agrochemical, and specialty chemicals research. It may be used to introduce cyclopentyl groups in medicinal chemistry programs and as a reactive intermediate in the production of polymers, coatings, or other materials where cyclopentyl functionality is desired. In fragrance and flavor chemistry, bromocyclopentane-derived intermediates may be used to access cyclopentyl-containing aroma components. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 167.93
    methanol 117.45
    isopropanol 194.18
    water 0.89
    ethyl acetate 323.74
    n-propanol 191.47
    acetone 529.5
    n-butanol 215.81
    acetonitrile 211.6
    DMF 334.44
    toluene 378.95
    isobutanol 184.11
    1,4-dioxane 623.72
    methyl acetate 302.48
    THF 1009.2
    2-butanone 458.5
    n-pentanol 166.29
    sec-butanol 215.91
    n-hexane 133.56
    ethylene glycol 50.34
    NMP 629.59
    cyclohexane 333.14
    DMSO 502.74
    n-butyl acetate 421.81
    n-octanol 195.65
    chloroform 1019.06
    n-propyl acetate 275.05
    acetic acid 297.46
    dichloromethane 719.76
    cyclohexanone 789.93
    propylene glycol 88.7
    isopropyl acetate 274.17
    DMAc 359.14
    2-ethoxyethanol 225.1
    isopentanol 211.66
    n-heptane 208.75
    ethyl formate 186.54
    1,2-dichloroethane 462.61
    n-hexanol 273.32
    2-methoxyethanol 278.81
    isobutyl acetate 237.17
    tetrachloromethane 320.27
    n-pentyl acetate 299.24
    transcutol 871.26
    n-heptanol 179.15
    ethylbenzene 199.6
    MIBK 286.27
    2-propoxyethanol 356.75
    tert-butanol 301.33
    MTBE 345.11
    2-butoxyethanol 259.81
    propionic acid 224.75
    o-xylene 270.49
    formic acid 48.42
    diethyl ether 338.96
    m-xylene 273.78
    p-xylene 280.15
    chlorobenzene 450.82
    dimethyl carbonate 134.02
    n-octane 80.14
    formamide 75.2
    cyclopentanone 889.2
    2-pentanone 389.19
    anisole 322.98
    cyclopentyl methyl ether 561.4
    gamma-butyrolactone 727.94
    1-methoxy-2-propanol 274.97
    pyridine 568.59
    3-pentanone 359.21
    furfural 613.58
    n-dodecane 59.9
    diethylene glycol 236.09
    diisopropyl ether 193.98
    tert-amyl alcohol 267.55
    acetylacetone 487.2
    n-hexadecane 68.32
    acetophenone 334.83
    methyl propionate 252.3
    isopentyl acetate 402.71
    trichloroethylene 847.85
    n-nonanol 184.83
    cyclohexanol 382.14
    benzyl alcohol 232.33
    2-ethylhexanol 253.56
    isooctanol 168.74
    dipropyl ether 390.97
    1,2-dichlorobenzene 400.45
    ethyl lactate 133.32
    propylene carbonate 441.9
    n-methylformamide 141.55
    2-pentanol 201.7
    n-pentane 133.3
    1-propoxy-2-propanol 366.19
    1-methoxy-2-propyl acetate 399.23
    2-(2-methoxypropoxy) propanol 307.6
    mesitylene 220.2
    ε-caprolactone 561.26
    p-cymene 221.98
    epichlorohydrin 636.81
    1,1,1-trichloroethane 697.78
    2-aminoethanol 89.07
    morpholine-4-carbaldehyde 523.12
    sulfolane 917.65
    2,2,4-trimethylpentane 90.31
    2-methyltetrahydrofuran 750.89
    n-hexyl acetate 376.02
    isooctane 74.08
    2-(2-butoxyethoxy)ethanol 387.21
    sec-butyl acetate 233.47
    tert-butyl acetate 352.95
    decalin 128.72
    glycerin 124.72
    diglyme 651.47
    acrylic acid 207.58
    isopropyl myristate 209.69
    n-butyric acid 316.54
    acetyl acetate 298.3
    di(2-ethylhexyl) phthalate 166.38
    ethyl propionate 227.06
    nitromethane 360.58
    1,2-diethoxyethane 457.04
    benzonitrile 315.74
    trioctyl phosphate 129.73
    1-bromopropane 393.87
    gamma-valerolactone 751.43
    n-decanol 150.42
    triethyl phosphate 175.78
    4-methyl-2-pentanol 151.02
    propionitrile 206.92
    vinylene carbonate 370.6
    1,1,2-trichlorotrifluoroethane 458.86
    DMS 266.47
    cumene 158.33
    2-octanol 156.85
    2-hexanone 318.81
    octyl acetate 237.35
    limonene 338.31
    1,2-dimethoxyethane 415.54
    ethyl orthosilicate 181.31
    tributyl phosphate 157.43
    diacetone alcohol 344.92
    N,N-dimethylaniline 241.1
    acrylonitrile 227.2
    aniline 315.67
    1,3-propanediol 147.95
    bromobenzene 506.84
    dibromomethane 620.03
    1,1,2,2-tetrachloroethane 742.61
    2-methyl-cyclohexyl acetate 309.24
    tetrabutyl urea 201.49
    diisobutyl methanol 207.24
    2-phenylethanol 268.37
    styrene 250.13
    dioctyl adipate 263.33
    dimethyl sulfate 221.38
    ethyl butyrate 339.99
    methyl lactate 150.31
    butyl lactate 218.02
    diethyl carbonate 221.53
    propanediol butyl ether 252.7
    triethyl orthoformate 269.35
    p-tert-butyltoluene 232.58
    methyl 4-tert-butylbenzoate 318.69
    morpholine 560.27
    tert-butylamine 232.86
    n-dodecanol 130.82
    dimethoxymethane 275.7
    ethylene carbonate 319.52
    cyrene 297.22
    2-ethoxyethyl acetate 357.93
    2-ethylhexyl acetate 354.8
    1,2,4-trichlorobenzene 499.42
    4-methylpyridine 504.27
    dibutyl ether 320.19
    2,6-dimethyl-4-heptanol 207.24
    DEF 322.82
    dimethyl isosorbide 529.01
    tetrachloroethylene 540.21
    eugenol 264.87
    triacetin 387.14
    span 80 335.92
    1,4-butanediol 85.35
    1,1-dichloroethane 537.77
    2-methyl-1-pentanol 178.59
    methyl formate 136.48
    2-methyl-1-butanol 202.01
    n-decane 89.85
    butyronitrile 232.43
    3,7-dimethyl-1-octanol 228.42
    1-chlorooctane 209.58
    1-chlorotetradecane 113.56
    n-nonane 94.67
    undecane 70.13
    tert-butylcyclohexane 112.77
    cyclooctane 142.89
    cyclopentanol 388.87
    tetrahydropyran 701.0
    tert-amyl methyl ether 291.03
    2,5,8-trioxanonane 485.81
    1-hexene 226.67
    2-isopropoxyethanol 216.54
    2,2,2-trifluoroethanol 137.82
    methyl butyrate 284.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction