Bis(dimethylthiocarbamoyl) sulfide

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  • Identifiers

    CAS number
    97-74-5

    Molecular formula
    C6H12N2S3

    SMILES
    CN(C)C(=S)SC(=S)N(C)C

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Sulfurous 65.59%
    Onion 39.34%
    Meaty 36.28%
    Savory 35.4%
    Fruity 34.73%
    Cheesy 34.47%
    Roasted 32.9%
    Garlic 32.54%
    Tropical 32.24%
    Alliaceous 31.71%

     

    Flavor
    Cooked 28.27%
    Sulfurous 27.88%
    Roasted 25.86%
    Onion 25.06%
    Sulfury 23.6%
    Cabbage 22.07%
    Taco 20.81%
    Acrid 20.57%
    Scallion 20.21%
    Matches 19.99%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    7.54 (neutral)

    Molecular weight
    208.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    356°C

    Melting point expt.

    • 109.5 °C

    Flash point

    • 116.15 ˚C est.

    Solubility expt.

    • Soluble in aromatic solvents

  • Synonyms

    • Tetramethylthiuram monosulfide
    • 97-74-5
    • BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE
    • Unads
    • Monothiuram
    • TMTM
    • Mono-thiurad
    • Thiuram MM
    • Aceto TMTM
    • TMTMS
    • Tetramethylthiuram sulfide
    • Cyuram MS
    • Ekagom TM
    • Vulkacit ms
    • Vulkacit Thiuram MS
    • Pennac MS
    • Tetramethylthiuramide sulfide
    • Bis(dimethylthiocarbamyl) sulfide
    • Usaf ek-p-6255
    • Usaf B-32
    • Monex
    • Tetramethylthiuram monosulphide
    • Tetramethylthiurammonium sulfide
    • Tetramethylthiuramonosulfide
    • Vulkacit thiuram ms/C
    • Thiuram monosulfide, tetramethyl-
    • Bis(dimethylthiocarbamyl) monosulfide
    • Tetramethyldithiocarbamic acid anhydrosulfide
    • Carbamic anhydride, tetramethyltrithio-
    • Monosulfure de tetramethylthiurame
    • N,N,N',N'-Tetramethylthiuram monosulfide
    • NSC 3400
    • NSC 4767
    • Sulfide, bis(dimethylthiocarbamoyl)
    • Bis(dimethylthiocarbamoyl)sulfide
    • Thiodicarbonic diamide ([(H2N)C(S)]2S), tetramethyl-
    • HSDB 2902
    • dimethylcarbamothioyl N,N-dimethylcarbamodithioate
    • Sulfide, bis((dimethylamino)thioxomethyl)
    • Formamide, 1,1'-thiobis(N,N-dimethylthio-
    • EINECS 202-605-7
    • Carbamic acid, dimethyldithio-, anhydrosulfide
    • Carbamodithioic acid, dimethyl-, anhydrosulfide
    • CP 2113
    • BRN 1775650
    • 01W430XXSQ
    • DTXSID0021333
    • AI3-00984
    • Monosulfure de tetramethylthiurame [French]
    • NSC-3400
    • NSC-4767
    • Thionex rubber accelerator
    • CHEMBL571700
    • DTXCID801333
    • NSC4767
    • EC 202-605-7
    • 4-04-00-00238 (Beilstein Handbook Reference)
    • BISDIMETHYLTHIOCARBAMYL SULFIDE
    • BISDIMETHYLTHIOCARBAMYL SULPHIDE
    • Thiodicarbonic diamide (((H2N)C(S))2S), tetramethyl-
    • N,N-dimethyl[(dimethylcarbamothioyl)sulfanyl]carbothioamide
    • NCGC00159424-02
    • NCGC00159424-04
    • Sulfide, bis(dimethylthiocarbamoyl) (8CI)
    • N,N,N',N'-Tetramethyldicarbonotrithioic diamide
    • BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE [HSDB]
    • Carbamic acid, anhydrosulfide
    • Carbamodithioic acid, anhydrosulfide
    • Thiodicarbonic diamide (((H2N)C(S))2S), N,N,N',N'-tetramethyl-
    • N,N',N'-Tetramethylthiuram monosulfide
    • CAS-97-74-5
    • Formamide,1'-thiobis[N,N-dimethylthio-
    • Sulfide, bis[(dimethylamino)thioxomethyl]
    • WLN: 1N1 & YUS & SYUS & N1 & 1
    • MFCD00014870
    • N,N-dimethyl((dimethylcarbamothioyl)sulfanyl)carbothioamide
    • UNII-01W430XXSQ
    • Monothiurad
    • THIODICARBONIC DIAMIDE [((H2N)C(S))2S], TETRAMETHYL-
    • Thiodicarbonic diamide ([(H2N)C(S)]2S), N,N,N',N'-tetramethyl-
    • Perkacit TMTM
    • SCHEMBL23048
    • tetramethylthiuram-monosulfide
    • Thiuram monosulfide, tetramethyl
    • REQPQFUJGGOFQL-UHFFFAOYSA-
    • NSC3400
    • Tetramethylthiuram monosulfide, 97%
    • Thiodicarbonic diamide, tetramethyl-
    • Tox21_111656
    • Tox21_201554
    • Tox21_302880
    • BDBM50414949
    • s2432
    • Carbamic anhydride, tetramethyltrithio
    • AKOS015850780
    • Tox21_111656_1
    • DB14178
    • HY-W020246
    • Bis(dimethylaminethiocarbonyl)monosulfide
    • Formamide, 1,1'thiobis(N,Ndimethylthio
    • N,N,N',N'Tetramethylthiuram monosulfide
    • NCGC00159424-03
    • NCGC00159424-05
    • NCGC00256325-01
    • NCGC00259103-01
    • DA-68082
    • LS-13171
    • Carbamic acid, dimethyldithio, anhydrosulfide
    • CS-0039286
    • NS00007980
    • T0157
    • Carbamodithioic acid, dimethyl, anhydrosulfide
    • E80911
    • SBI-0654050.0001
    • EN300-7719162
    • N,N,N',N'-Tetramethyldicarbonotrithioic diamide #
    • SR-01000944762
    • SR-01000944762-1
    • BRD-K36889451-001-01-1
    • Q27231461
    • Thiodicarbonic diamide ([(H2-N)C(S)]2-S), tetramethyl-
    • InChI=1/C6H12N2S3/c1-7(2)5(9)11-6(10)8(3)4/h1-4H3
    • CARBAMIC ANHYDRIDE, TETRAMETHYLTRITHIOFORMAMIDE, 1,1'-THIOBIS(N,N-DIMETHYLTHIO-
    • [(2R,3S,5R)-3-hydroxy-5-[4-(methoxyamino)-2-oxo-pyrimidin-1-yl]tetrahydrofuran-2-yl]methyl dihydrogen phosphate

  • Applications

    Bis(dimethylthiocarbamoyl) sulfide (CAS 97-74-5) is used primarily as an organic-synthesis intermediate, serving as a reagent to introduce the dimethylthiocarbamoyl motif into target molecules and to access thiocarbamate derivatives. It is also employed as a building block in polymer chemistry for functionalization and potential crosslinking of coatings, inks, and plastics. Additionally, it may be evaluated as a precursor in early-stage research for pharmaceuticals or agrochemicals, and as a specialty reagent for preparing thiocarbamate-containing ligands or catalysts. Its applications are highly specialized and subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.14
    methanol 15.47
    isopropanol 6.29
    water 1.1
    ethyl acetate 11.37
    n-propanol 7.85
    acetone 21.8
    n-butanol 6.14
    acetonitrile 15.8
    DMF 115.29
    toluene 8.41
    isobutanol 5.77
    1,4-dioxane 44.18
    methyl acetate 23.94
    THF 64.1
    2-butanone 17.05
    n-pentanol 5.3
    sec-butanol 5.09
    n-hexane 0.18
    ethylene glycol 12.74
    NMP 185.59
    cyclohexane 1.58
    DMSO 93.12
    n-butyl acetate 14.94
    n-octanol 6.68
    chloroform 63.32
    n-propyl acetate 10.42
    acetic acid 23.36
    dichloromethane 51.82
    cyclohexanone 45.19
    propylene glycol 10.23
    isopropyl acetate 6.43
    DMAc 107.42
    2-ethoxyethanol 17.84
    isopentanol 4.84
    n-heptane 0.86
    ethyl formate 27.29
    1,2-dichloroethane 25.63
    n-hexanol 8.9
    2-methoxyethanol 37.69
    isobutyl acetate 7.56
    tetrachloromethane 12.87
    n-pentyl acetate 11.86
    transcutol 29.64
    n-heptanol 6.58
    ethylbenzene 4.6
    MIBK 5.94
    2-propoxyethanol 26.11
    tert-butanol 7.84
    MTBE 4.7
    2-butoxyethanol 17.45
    propionic acid 16.92
    o-xylene 8.24
    formic acid 24.09
    diethyl ether 3.97
    m-xylene 5.47
    p-xylene 8.71
    chlorobenzene 23.24
    dimethyl carbonate 16.2
    n-octane 0.57
    formamide 37.44
    cyclopentanone 71.23
    2-pentanone 9.9
    anisole 15.52
    cyclopentyl methyl ether 17.66
    gamma-butyrolactone 96.5
    1-methoxy-2-propanol 20.74
    pyridine 52.74
    3-pentanone 9.19
    furfural 131.53
    n-dodecane 0.69
    diethylene glycol 30.22
    diisopropyl ether 1.25
    tert-amyl alcohol 6.42
    acetylacetone 18.69
    n-hexadecane 0.8
    acetophenone 26.06
    methyl propionate 17.32
    isopentyl acetate 12.99
    trichloroethylene 69.56
    n-nonanol 6.88
    cyclohexanol 11.29
    benzyl alcohol 20.81
    2-ethylhexanol 8.1
    isooctanol 5.39
    dipropyl ether 5.39
    1,2-dichlorobenzene 28.95
    ethyl lactate 13.18
    propylene carbonate 52.22
    n-methylformamide 53.09
    2-pentanol 3.21
    n-pentane 0.3
    1-propoxy-2-propanol 18.75
    1-methoxy-2-propyl acetate 20.2
    2-(2-methoxypropoxy) propanol 19.64
    mesitylene 3.27
    ε-caprolactone 41.93
    p-cymene 7.55
    epichlorohydrin 67.45
    1,1,1-trichloroethane 25.07
    2-aminoethanol 13.12
    morpholine-4-carbaldehyde 119.38
    sulfolane 143.57
    2,2,4-trimethylpentane 0.38
    2-methyltetrahydrofuran 30.67
    n-hexyl acetate 13.46
    isooctane 0.2
    2-(2-butoxyethoxy)ethanol 21.91
    sec-butyl acetate 5.84
    tert-butyl acetate 7.61
    decalin 1.06
    glycerin 21.56
    diglyme 43.29
    acrylic acid 24.56
    isopropyl myristate 6.18
    n-butyric acid 16.27
    acetyl acetate 12.51
    di(2-ethylhexyl) phthalate 12.41
    ethyl propionate 8.73
    nitromethane 64.28
    1,2-diethoxyethane 11.72
    benzonitrile 33.94
    trioctyl phosphate 8.42
    1-bromopropane 7.14
    gamma-valerolactone 103.12
    n-decanol 5.64
    triethyl phosphate 12.38
    4-methyl-2-pentanol 2.36
    propionitrile 12.33
    vinylene carbonate 55.66
    1,1,2-trichlorotrifluoroethane 88.29
    DMS 19.57
    cumene 4.22
    2-octanol 4.4
    2-hexanone 9.39
    octyl acetate 9.23
    limonene 9.33
    1,2-dimethoxyethane 34.19
    ethyl orthosilicate 10.37
    tributyl phosphate 9.28
    diacetone alcohol 15.27
    N,N-dimethylaniline 16.49
    acrylonitrile 25.71
    aniline 20.61
    1,3-propanediol 13.96
    bromobenzene 20.56
    dibromomethane 26.02
    1,1,2,2-tetrachloroethane 62.75
    2-methyl-cyclohexyl acetate 18.36
    tetrabutyl urea 16.11
    diisobutyl methanol 4.4
    2-phenylethanol 24.52
    styrene 6.66
    dioctyl adipate 13.2
    dimethyl sulfate 42.41
    ethyl butyrate 12.42
    methyl lactate 20.7
    butyl lactate 15.58
    diethyl carbonate 11.87
    propanediol butyl ether 17.82
    triethyl orthoformate 11.72
    p-tert-butyltoluene 7.29
    methyl 4-tert-butylbenzoate 23.43
    morpholine 47.85
    tert-butylamine 4.13
    n-dodecanol 4.55
    dimethoxymethane 32.11
    ethylene carbonate 35.91
    cyrene 46.65
    2-ethoxyethyl acetate 19.9
    2-ethylhexyl acetate 11.7
    1,2,4-trichlorobenzene 44.01
    4-methylpyridine 42.26
    dibutyl ether 5.29
    2,6-dimethyl-4-heptanol 4.4
    DEF 25.2
    dimethyl isosorbide 55.76
    tetrachloroethylene 44.45
    eugenol 28.16
    triacetin 19.89
    span 80 20.5
    1,4-butanediol 7.83
    1,1-dichloroethane 16.89
    2-methyl-1-pentanol 4.7
    methyl formate 53.65
    2-methyl-1-butanol 4.64
    n-decane 0.94
    butyronitrile 10.85
    3,7-dimethyl-1-octanol 6.71
    1-chlorooctane 4.76
    1-chlorotetradecane 2.22
    n-nonane 0.73
    undecane 0.79
    tert-butylcyclohexane 0.82
    cyclooctane 0.52
    cyclopentanol 20.16
    tetrahydropyran 21.57
    tert-amyl methyl ether 4.85
    2,5,8-trioxanonane 35.67
    1-hexene 1.04
    2-isopropoxyethanol 11.3
    2,2,2-trifluoroethanol 22.18
    methyl butyrate 14.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction