Bis(2,4-di-tert-butyl-6-methyl phenyl) ethyl phosphite

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  • Identifiers

    CAS number
    145650-60-8

    Molecular formula
    C32H51O3P

    SMILES
    CCOP(OC1=C(C=C(C=C1C)C(C)(C)C)C(C)(C)C)OC2=C(C=C(C=C2C)C(C)(C)C)C(C)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 57.26%
    Dry 37.75%
    Musk 35.31%
    Amber 34.59%
    Vetiver 34.51%
    Fruity 32.9%
    Green 31.55%
    Leathery 30.41%
    Floral 29.91%
    Phenolic 28.01%

     

    Flavor
    Camphor 34.66%
    Musty 32.46%
    Mild 31.14%
    Woody 27.12%
    Phenolic 26.08%
    Earth 24.31%
    Green pepper 22.3%
    Earthy 21.57%
    Carrot 21.48%
    Thymol 21.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.5

    pKa est.
    6.24 (neutral)

    Molecular weight
    514.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    438°C

    Flash point

    • 189.14 ˚C est.

  • Synonyms

    • 145650-60-8
    • BIS(2,4-DI-TERT-BUTYL-6-METHYL PHENYL) ETHYL PHOSPHITE
    • 4EL3Y5QX1X
    • IRGAFOS 38
    • bis(2,4-di-tert-butyl-6-methylphenyl) ethyl phosphite
    • Phosphorous acid, bis(2,4-bis(1,1-dimethylethyl)-6-methylphenyl) ethyl ester
    • Phosphorous acid, bis[2,4-bis(1,1-dimethylethyl)-6-methylphenyl] ethyl ester
    • ETHYL BIS(2-METHYL-4,6-DI(TERT-BUTYLPHENYNOL) PHOSPHATE
    • PHOSPHOROUS ACID, BIS(2,4-BIS(1,1-DIMETHYLETHYL)-6-METHYLPHENYL)ETHYL ESTER
    • RefChem:568604
    • UNII-4EL3Y5QX1X
    • bis(2,4-ditert-butyl-6-methylphenyl) ethyl phosphite
    • bis(2,4-di-tert-butyl-6-methylphenyl)ethyl phosphite
    • SCHEMBL194310
    • DTXSID6051728
    • SCHEMBL29354551
    • NS00040887
    • Q27259491
    • 145650-60-8

  • Applications

    Bis(2,4-di-tert-butyl-6-methyl phenyl) ethyl phosphite, CAS 145650-60-8, is an organophosphite widely used as a thermal stabilizer and antioxidant for polymers and coatings during compounding and processing, particularly in polyolefins and PVC. It also serves as a processing additive in coatings and inks to enhance heat stability and oxidative resistance. In lubricant formulations it acts as an antioxidant/stabilizer to retard oxidation. In adhesive and sealant systems it functions as a stabilizer to improve aging resistance. Additionally, it can be used as an intermediate in the synthesis of other organophosphite stabilizers and antioxidants; subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 46.3
    methanol 15.16
    isopropanol 61.57
    water 0.17
    ethyl acetate 181.99
    n-propanol 70.28
    acetone 231.19
    n-butanol 73.25
    acetonitrile 74.43
    DMF 305.39
    toluene 206.4
    isobutanol 74.2
    1,4-dioxane 241.96
    methyl acetate 172.46
    THF 685.8
    2-butanone 260.15
    n-pentanol 93.19
    sec-butanol 92.72
    n-hexane 43.74
    ethylene glycol 7.32
    NMP 667.06
    cyclohexane 38.9
    DMSO 181.71
    n-butyl acetate 235.13
    n-octanol 99.87
    chloroform 794.32
    n-propyl acetate 207.37
    acetic acid 87.15
    dichloromethane 583.26
    cyclohexanone 415.98
    propylene glycol 29.2
    isopropyl acetate 178.92
    DMAc 488.59
    2-ethoxyethanol 113.58
    isopentanol 82.1
    n-heptane 37.97
    ethyl formate 108.92
    1,2-dichloroethane 332.82
    n-hexanol 105.7
    2-methoxyethanol 94.91
    isobutyl acetate 200.19
    tetrachloromethane 115.05
    n-pentyl acetate 269.92
    transcutol 214.37
    n-heptanol 104.92
    ethylbenzene 141.16
    MIBK 177.93
    2-propoxyethanol 178.32
    tert-butanol 99.21
    MTBE 174.13
    2-butoxyethanol 181.13
    propionic acid 99.23
    o-xylene 130.58
    formic acid 14.47
    diethyl ether 127.69
    m-xylene 151.12
    p-xylene 210.96
    chlorobenzene 316.42
    dimethyl carbonate 120.9
    n-octane 25.33
    formamide 30.41
    cyclopentanone 600.74
    2-pentanone 228.0
    anisole 215.29
    cyclopentyl methyl ether 325.05
    gamma-butyrolactone 570.43
    1-methoxy-2-propanol 137.58
    pyridine 352.5
    3-pentanone 200.18
    furfural 378.88
    n-dodecane 15.06
    diethylene glycol 64.32
    diisopropyl ether 78.05
    tert-amyl alcohol 120.67
    acetylacetone 283.98
    n-hexadecane 17.45
    acetophenone 254.25
    methyl propionate 189.06
    isopentyl acetate 242.44
    trichloroethylene 802.05
    n-nonanol 102.09
    cyclohexanol 115.92
    benzyl alcohol 143.15
    2-ethylhexanol 107.17
    isooctanol 104.36
    dipropyl ether 155.5
    1,2-dichlorobenzene 295.26
    ethyl lactate 109.4
    propylene carbonate 354.94
    n-methylformamide 98.53
    2-pentanol 83.88
    n-pentane 28.73
    1-propoxy-2-propanol 186.66
    1-methoxy-2-propyl acetate 246.93
    2-(2-methoxypropoxy) propanol 155.32
    mesitylene 95.5
    ε-caprolactone 391.73
    p-cymene 103.87
    epichlorohydrin 580.38
    1,1,1-trichloroethane 465.85
    2-aminoethanol 25.24
    morpholine-4-carbaldehyde 422.51
    sulfolane 663.86
    2,2,4-trimethylpentane 25.07
    2-methyltetrahydrofuran 432.3
    n-hexyl acetate 271.6
    isooctane 17.79
    2-(2-butoxyethoxy)ethanol 183.34
    sec-butyl acetate 177.85
    tert-butyl acetate 230.93
    decalin 37.61
    glycerin 31.09
    diglyme 300.44
    acrylic acid 84.84
    isopropyl myristate 117.93
    n-butyric acid 148.28
    acetyl acetate 145.78
    di(2-ethylhexyl) phthalate 126.68
    ethyl propionate 183.09
    nitromethane 193.6
    1,2-diethoxyethane 176.46
    benzonitrile 185.09
    trioctyl phosphate 98.44
    1-bromopropane 226.31
    gamma-valerolactone 632.4
    n-decanol 73.83
    triethyl phosphate 114.5
    4-methyl-2-pentanol 69.62
    propionitrile 96.74
    vinylene carbonate 274.1
    1,1,2-trichlorotrifluoroethane 319.42
    DMS 210.73
    cumene 104.57
    2-octanol 101.39
    2-hexanone 242.38
    octyl acetate 145.75
    limonene 126.34
    1,2-dimethoxyethane 232.97
    ethyl orthosilicate 117.86
    tributyl phosphate 105.77
    diacetone alcohol 196.89
    N,N-dimethylaniline 195.93
    acrylonitrile 104.45
    aniline 153.27
    1,3-propanediol 40.25
    bromobenzene 381.96
    dibromomethane 396.38
    1,1,2,2-tetrachloroethane 655.29
    2-methyl-cyclohexyl acetate 219.77
    tetrabutyl urea 158.45
    diisobutyl methanol 71.73
    2-phenylethanol 167.69
    styrene 155.16
    dioctyl adipate 168.62
    dimethyl sulfate 241.93
    ethyl butyrate 187.83
    methyl lactate 100.42
    butyl lactate 194.16
    diethyl carbonate 124.67
    propanediol butyl ether 141.73
    triethyl orthoformate 167.34
    p-tert-butyltoluene 103.45
    methyl 4-tert-butylbenzoate 263.57
    morpholine 279.59
    tert-butylamine 70.86
    n-dodecanol 55.34
    dimethoxymethane 201.64
    ethylene carbonate 220.88
    cyrene 235.93
    2-ethoxyethyl acetate 266.66
    2-ethylhexyl acetate 230.21
    1,2,4-trichlorobenzene 361.39
    4-methylpyridine 384.65
    dibutyl ether 134.73
    2,6-dimethyl-4-heptanol 71.73
    DEF 243.75
    dimethyl isosorbide 358.87
    tetrachloroethylene 317.13
    eugenol 206.97
    triacetin 237.34
    span 80 174.66
    1,4-butanediol 30.97
    1,1-dichloroethane 376.18
    2-methyl-1-pentanol 108.28
    methyl formate 92.4
    2-methyl-1-butanol 89.56
    n-decane 28.96
    butyronitrile 112.51
    3,7-dimethyl-1-octanol 89.67
    1-chlorooctane 106.32
    1-chlorotetradecane 43.46
    n-nonane 28.38
    undecane 19.99
    tert-butylcyclohexane 40.14
    cyclooctane 21.2
    cyclopentanol 167.42
    tetrahydropyran 289.27
    tert-amyl methyl ether 162.94
    2,5,8-trioxanonane 202.85
    1-hexene 117.54
    2-isopropoxyethanol 126.18
    2,2,2-trifluoroethanol 54.79
    methyl butyrate 234.98

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction