Bis(2-ethylhexyl) adipate

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  • Identifiers

    CAS number
    103-23-1

    Molecular formula
    C22H42O4

    SMILES
    CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 65.4%
    Oily 49.22%
    Fatty 41.76%
    Herbal 34.17%
    Winey 25.85%
    Peach 25.55%
    Waxy 24.41%
    Lactonic 23.65%
    Odorless 22.53%
    Fermented 21.47%

     

    Flavor
    Fruity 64.23%
    Waxy 50.63%
    Green 50.11%
    Oily 44.14%
    Sweet 33.62%
    Tropical 33.34%
    Apple 31.56%
    Herbal 31.06%
    Fatty 30.21%
    Wine 29.24%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.8

    pKa est.
    7.45 (neutral)

    Molecular weight
    370.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • -90 °F (NTP, 1992)
    • -67.8 °C
    • 7.49 °C (280.65 K)

    Boiling point

    • 783 °F at 760 mmHg (NTP, 1992)
    • 214 °C @ 5 mm Hg
    • Normal Boiling Point: 404.84 °C (687 K)
    • 416.00 to 418.00 °C. @ 760.00 mm Hg

    Flash point

    • 178.51 ˚C est.
    • 385 °F (NTP, 1992)
    • 196 °C
    • 402 °F (206 °C) (OPEN CUP)

    Solubility expt.

    • less than 0.1 mg/mL at 72 °F (NTP, 1992)
    • SOL IN MOST ORG SOLVENTS; INSOL OR VERY SLIGHTLY SOL IN GLYCERINE & GLYCOLS
    • Soluble in ethanol, ethyl ether, acetone, and acetic acid
    • In water, 0.78 mg/l @ 22 °C
    • INSOL IN WATER @ 25 °C; INSOL OR VERY SLIGHTLY SOL IN GLYCERINE & GLYCOLS; SOL IN MOST ORGANIC SOLVENTS
    • In water, 0.78 mg/l @ 22 °C
    • 0.00078 mg/mL at 22 °C
    • Practically insoluble or insoluble in water
    • Soluble (in ethanol)

  • Synonyms

    • BIS(2-ETHYLHEXYL) ADIPATE
    • 103-23-1
    • Di(2-ethylhexyl) adipate
    • Diethylhexyl adipate
    • DEHA
    • Bis(2-ethylhexyl)hexanedioate
    • Di(2-ethylhexyl)adipate
    • Octyl adipate
    • Bis(2-ethylhexyl) hexanedioate
    • Plastomoll DOA
    • Vestinol OA
    • Bisoflex DOA
    • Crodamol DOA
    • Effomoll DOA
    • Kodaflex DOA
    • Monoplex DOA
    • BEHA
    • Truflex DOA
    • BIS(2-ETHYLHEXYL)ADIPATE
    • Adipol 2EH
    • Staflex doa
    • Uniflex doa
    • Reomol doa
    • Wickenol 158
    • Di-2-ethylhexyl adipate
    • Lankroflex DOA
    • Sansocizer DOA
    • Ergoplast ADDO
    • Plasthall DOA
    • Adimoll DO
    • Mollan S
    • Flexol A 26
    • Sicol 250
    • Hexanedioic acid, bis(2-ethylhexyl) ester
    • Rucoflex plasticizer doa
    • Jayflex DOA 2
    • Kemester 5652
    • Effomoll DA
    • Arlamol DOA
    • Hatcol 2908
    • WITAMOL 320
    • Adipic acid, bis(2-ethylhexyl) ester
    • Flexol plasticizer 10-A
    • Flexol plasticizer A-26
    • Morflex 310
    • Vistone A 10
    • Di-(2-ethylhexyl) adipate
    • Octyl adipate (VAN)
    • Adipic acid di(2-ethylhexyl) ester
    • Effemoll doa
    • NCI-C54386
    • Dioctyl adipate (VAN)
    • DOA
    • CCRIS 236
    • PX-238
    • HSDB 343
    • Bis-(2-ethylhexyl)ester kyseliny adipove
    • Hexanedioic acid bis(2-ethylhexyl) ester
    • Palatinol DOA
    • Monsanto DOA
    • UNII-MBY1SL921L
    • EINECS 203-090-1
    • MBY1SL921L
    • K 3220
    • BRN 1803774
    • DTXSID0020606
    • CHEBI:34675
    • Good-rite GP-223
    • Adipic acid di[2-ethylhexyl]ester
    • 1,6-bis(2-ethylhexyl) hexanedioate
    • Hexanedioic acid, 1,6-bis(2-ethylhexyl) ester
    • NSC-56775
    • Bis-(2-ethylhexyl)ester kyseliny adipove [Czech]
    • DTXCID40606
    • MLS002152897
    • ADIPIC ACID BIS(2-ETHYLHEXYL) ESTER
    • EC 203-090-1
    • 4-02-00-01964 (Beilstein Handbook Reference)
    • Adipic acid, bis-2-ethylhexyl ester
    • DI(2-ETHYLHEXYL) ADIPATE [IARC]
    • SMR001224508
    • DI-(2-ETHYLHEXYL)ADIPATE [MART.]
    • BIS(2-ETHYLHEXYL)HEXANEDIOATE [HSDB]
    • Bis-(2-ethylhexyl)ester kyseliny adipove (czech)
    • Adipic acid-bis-2-ethylhexylester
    • Adipic acid di(2-ethylhexyl)ester
    • DI(2-ETHYLHEXYL) ADIPATE (IARC)
    • 203-090-1
    • 2072051-04-6
    • CAS-103-23-1
    • DI-(2-ETHYLHEXYL)ADIPATE (MART.)
    • keme ster 5652
    • USS 700
    • NSC 56775
    • AI3-28579
    • DOA Plasticizer
    • Bis(2-ethylhexyl) hexanedio ate
    • Jayflex DOA
    • Merrol DOA
    • Witcizer 412
    • Flexol A26
    • MFCD00009496
    • Adipic acid bis (2-ethylhexyl) ester
    • Di2ethylhexyl adipate
    • DIACIZER DOA
    • i-2-ethylhexyl adipate
    • Flexol plasticizer 10A
    • Flexol plasticizer A26
    • Bis(2ethylhexyl) adipate
    • di (2-ethylhexyl) adipate
    • cid_7641
    • NCIOpen2_007625
    • SCHEMBL27423
    • Bis(2ethylhexyl) hexanedioate
    • Hexadioic acid, dioctyl ester
    • Hexanedioc acid, dioctyl ester
    • CHEMBL1414950
    • BDBM74247
    • Adipic acid, bis-2-ethylhexyl ester 100 microg/mL in Acetone
    • Bis(2-ethylhexyl) adipate, 99%
    • PX238
    • DIETHYLHEXYL ADIPATE [INCI]
    • NSC56775
    • Tox21_202231
    • Tox21_300564
    • Adipic acid, bis(2ethylhexyl) ester
    • Adipic acid, di(2-ethylhexyl) ester
    • Bis(2-ethylhexyl) adipate, >=99%

  • Applications

    Bis(2-ethylhexyl) adipate (DEHA, CAS 103-23-1) is a long-chain, low-temperature plasticizer prized for imparting softness, flexibility and glass-transition depression to a broad range of polymers; it is widely employed in flexible PVC for cling film, food-grade wraps, medical tubing, synthetic leather, protective gloves, cable insulation and cold-resistant rubber items, and also functions as a carrier solvent in agrochemicals, a biodegradable base oil for lubricants and hydraulic fluids, an internal lubricant in polymer processing, and an additive in nitrocellulose coatings, printing inks and pressure-sensitive adhesives; its low volatility, mild odour and limited migration meet stringent food-contact regulations while boosting end-product clarity, heat-sealability, weather resistance and service life.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 77.73
    methanol 65.9
    isopropanol 110.32
    water 0.09
    ethyl acetate 454.94
    n-propanol 111.18
    acetone 422.85
    n-butanol 128.33
    acetonitrile 188.56
    DMF 343.36
    toluene 242.46
    isobutanol 121.33
    1,4-dioxane 495.45
    methyl acetate 311.85
    THF 1014.49
    2-butanone 469.22
    n-pentanol 128.87
    sec-butanol 158.14
    n-hexane 38.28
    ethylene glycol 4.48
    NMP 717.1
    cyclohexane 170.36
    DMSO 446.73
    n-butyl acetate 387.98
    n-octanol 120.96
    chloroform 1397.89
    n-propyl acetate 430.41
    acetic acid 183.38
    dichloromethane 1426.32
    cyclohexanone 1177.31
    propylene glycol 15.24
    isopropyl acetate 394.91
    DMAc 707.48
    2-ethoxyethanol 200.71
    isopentanol 167.08
    n-heptane 20.51
    ethyl formate 195.21
    1,2-dichloroethane 932.66
    n-hexanol 99.8
    2-methoxyethanol 163.41
    isobutyl acetate 278.82
    tetrachloromethane 266.75
    n-pentyl acetate 550.24
    transcutol 767.51
    n-heptanol 104.07
    ethylbenzene 157.31
    MIBK 357.29
    2-propoxyethanol 197.86
    tert-butanol 183.64
    MTBE 314.22
    2-butoxyethanol 234.73
    propionic acid 147.38
    o-xylene 205.64
    formic acid 27.14
    diethyl ether 257.11
    m-xylene 157.04
    p-xylene 260.89
    chlorobenzene 480.89
    dimethyl carbonate 91.17
    n-octane 16.9
    formamide 59.9
    cyclopentanone 951.89
    2-pentanone 448.04
    anisole 267.45
    cyclopentyl methyl ether 460.0
    gamma-butyrolactone 814.43
    1-methoxy-2-propanol 178.26
    pyridine 608.54
    3-pentanone 354.99
    furfural 595.09
    n-dodecane 11.59
    diethylene glycol 71.66
    diisopropyl ether 111.14
    tert-amyl alcohol 225.54
    acetylacetone 537.89
    n-hexadecane 14.21
    acetophenone 368.06
    methyl propionate 262.15
    isopentyl acetate 400.43
    trichloroethylene 1545.52
    n-nonanol 118.67
    cyclohexanol 297.26
    benzyl alcohol 187.39
    2-ethylhexanol 107.04
    isooctanol 110.03
    dipropyl ether 162.11
    1,2-dichlorobenzene 502.54
    ethyl lactate 120.92
    propylene carbonate 465.77
    n-methylformamide 120.07
    2-pentanol 114.81
    n-pentane 24.42
    1-propoxy-2-propanol 185.45
    1-methoxy-2-propyl acetate 320.86
    2-(2-methoxypropoxy) propanol 220.36
    mesitylene 115.06
    ε-caprolactone 932.46
    p-cymene 97.79
    epichlorohydrin 953.02
    1,1,1-trichloroethane 1088.46
    2-aminoethanol 22.58
    morpholine-4-carbaldehyde 498.71
    sulfolane 954.04
    2,2,4-trimethylpentane 27.05
    2-methyltetrahydrofuran 789.87
    n-hexyl acetate 500.96
    isooctane 14.1
    2-(2-butoxyethoxy)ethanol 298.13
    sec-butyl acetate 331.87
    tert-butyl acetate 454.78
    decalin 58.44
    glycerin 24.6
    diglyme 692.32
    acrylic acid 100.37
    isopropyl myristate 154.57
    n-butyric acid 344.74
    acetyl acetate 317.76
    di(2-ethylhexyl) phthalate 141.73
    ethyl propionate 346.62
    nitromethane 405.42
    1,2-diethoxyethane 404.05
    benzonitrile 301.89
    trioctyl phosphate 100.17
    1-bromopropane 518.84
    gamma-valerolactone 1110.54
    n-decanol 77.5
    triethyl phosphate 166.57
    4-methyl-2-pentanol 88.19
    propionitrile 188.13
    vinylene carbonate 371.33
    1,1,2-trichlorotrifluoroethane 436.5
    DMS 259.28
    cumene 105.46
    2-octanol 112.46
    2-hexanone 413.94
    octyl acetate 198.42
    limonene 159.17
    1,2-dimethoxyethane 578.81
    ethyl orthosilicate 163.2
    tributyl phosphate 136.16
    diacetone alcohol 313.19
    N,N-dimethylaniline 183.49
    acrylonitrile 184.4
    aniline 193.75
    1,3-propanediol 60.97
    bromobenzene 572.47
    dibromomethane 931.59
    1,1,2,2-tetrachloroethane 1292.19
    2-methyl-cyclohexyl acetate 285.32
    tetrabutyl urea 189.27
    diisobutyl methanol 76.5
    2-phenylethanol 168.13
    styrene 198.22
    dioctyl adipate 254.89
    dimethyl sulfate 189.81
    ethyl butyrate 320.71
    methyl lactate 88.52
    butyl lactate 265.65
    diethyl carbonate 196.84
    propanediol butyl ether 176.39
    triethyl orthoformate 230.08
    p-tert-butyltoluene 90.4
    methyl 4-tert-butylbenzoate 336.7
    morpholine 577.04
    tert-butylamine 114.2
    n-dodecanol 54.11
    dimethoxymethane 226.79
    ethylene carbonate 353.91
    cyrene 240.15
    2-ethoxyethyl acetate 540.48
    2-ethylhexyl acetate 335.34
    1,2,4-trichlorobenzene 560.57
    4-methylpyridine 623.03
    dibutyl ether 247.19
    2,6-dimethyl-4-heptanol 76.5
    DEF 495.5
    dimethyl isosorbide 460.45
    tetrachloroethylene 854.14
    eugenol 259.84
    triacetin 414.3
    span 80 220.01
    1,4-butanediol 36.05
    1,1-dichloroethane 881.01
    2-methyl-1-pentanol 162.44
    methyl formate 101.29
    2-methyl-1-butanol 151.42
    n-decane 25.55
    butyronitrile 251.73
    3,7-dimethyl-1-octanol 124.23
    1-chlorooctane 143.0
    1-chlorotetradecane 42.63
    n-nonane 23.7
    undecane 16.16
    tert-butylcyclohexane 39.47
    cyclooctane 35.67
    cyclopentanol 266.75
    tetrahydropyran 755.17
    tert-amyl methyl ether 269.24
    2,5,8-trioxanonane 379.94
    1-hexene 127.08
    2-isopropoxyethanol 187.49
    2,2,2-trifluoroethanol 88.12
    methyl butyrate 521.35

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction