Bis(2-chloro-1-methylethyl) ether

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  • Identifiers

    CAS number
    108-60-1

    Molecular formula
    C6H12Cl2O

    SMILES
    CC(CCl)OC(C)CCl

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 38.93%
    Oily 26.22%
    Floral 25.28%
    Alcoholic 24.74%
    Green 24.7%
    Fishy 23.44%
    Nutty 22.92%
    Odorless 22.68%
    Fatty 21.63%
    Fresh 21.53%

     

    Flavor
    Sulfurous 49.76%
    Onion 37.3%
    Meaty 35.02%
    Sulfury 29.27%
    Fishy 24.41%
    Roasted 23.41%
    Bloody 22.27%
    Glue 21.85%
    Mild 21.5%
    Yeasty 21.35%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor detection in water= 3.2x10(-1) ppm, chemically pure.

  • Properties

    XLogP3-AA
    2.1

    pKa est.
    6.07 (neutral)

    Molecular weight
    171.06 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Melting point expt.

    • -143 °F (NTP, 1992)
    • -96.8 TO -101.8 °C
    • -97 - -102 °C

    Boiling point

    • 369.3 °F at 760 mmHg (NTP, 1992)
    • 187 °C @ 760 MM HG
    • 187 °C

    Flash point

    • 60.28 ˚C est.
    • 185 °F (NTP, 1992)
    • 85 °C
    • 185 °F (Open cup)
    • 85 °C o.c.

    Solubility expt.

    • less than 0.1 mg/mL at 72 °F (NTP, 1992)
    • MISCIBLE IN ORGANIC SOLVENTS
    • MISCIBLE IN ETHYL ALCOHOL, ETHYL ETHER, ACETONE
    • Water solubility of 1700 ppm at 20 °C.
    • Solubility in water, g/100ml at 20 °C: 0.2 (poor)

  • Synonyms

    • BIS(2-CHLORO-1-METHYLETHYL) ETHER
    • 108-60-1
    • 2,2'-Dichlorodiisopropyl ether
    • DCIP (nematocide)
    • Dichloroisopropyl ether
    • Dichlorodiisopropyl ether
    • Bis(2-chloro-1-methylethyl)ether
    • Nemamorte
    • Nemamol
    • Isopropylchlorex
    • 2,2'-Dichloroisopropyl ether
    • Bis(1-chloro-2-propyl) ether
    • 2,2'-Oxybis(1-chloropropane)
    • Ether, bis(2-chloro-1-methylethyl)
    • (2-Chloro-1-methylethyl) ether
    • NCI-C50044
    • NSC 2849
    • RCRA waste number U027
    • CCRIS 91
    • Propane, 2,2'-oxybis(1-chloro-
    • 1-chloro-2-(1-chloropropan-2-yloxy)propane
    • HSDB 503
    • Bis(beta-chloroisopropyl) ether
    • Bis(.beta.-chloroisopropyl) ether
    • Propane, 2,2'-oxybis[1-chloro-
    • UNII-0JJZ8LER32
    • EINECS 203-598-3
    • UN2490
    • BRN 1735833
    • Bis(2-chloro-1-methylethyl)ether, technical grade
    • .beta.,.beta.'-Dichlorodiisopropyl ether
    • DTXSID4020167
    • AI3-18183
    • NSC-2849
    • 0JJZ8LER32
    • 2,2-Dichloroisopropyl ether
    • DTXCID40167
    • bis-(2-Chloroisopropyl) Ether
    • Nemamort
    • CHEBI:82409
    • 3-01-00-01470 (Beilstein Handbook Reference)
    • (2-CHLORO-1-METHYLETHYL) ETHER [HSDB]
    • BIS(2-CHLORO-1-METHYLETHYL)ETHER [IARC]
    • Bis(beta-chloroisopropyl)ether
    • DDE cpd
    • BCMEE
    • BIS(2-CHLORO-1-METHYLETHYL)ETHER (IARC)
    • RCRA waste no. U027
    • beta,beta'-Dichlorodiisopropyl ether
    • Bis(1chloro2propyl) ether
    • Bis(2chloroisopropyl) ether
    • (2Chloro1methylethyl) ether
    • 2,2'Dichloroisopropyl ether
    • Bis(betachloroisopropyl)ether
    • 2,2'Oxybis(1chloropropane)
    • MLS002454389
    • 2,2'Dichlorodiisopropyl ether
    • Bis(betachloroisopropyl) ether
    • SCHEMBL380464
    • Propane, 2,2'oxybis(1chloro
    • Propane,2'-oxybis[1-chloro-
    • di-(1-chloro-2-propyl)-ether
    • CHEMBL1403227
    • Ether, bis(2chloro1methylethyl)
    • NSC2849
    • HMS3039J11
    • Tox21_201201
    • Bis-(2-chloro-1-methylethyl) ether
    • bis-(2-chloro-1-methylethyl)-ether
    • AKOS006273379
    • WLN: G1Y1 & OY1 & 1G
    • NCGC00091739-01
    • NCGC00091739-02
    • NCGC00258753-01
    • 52438-91-2
    • CAS-108-60-1
    • SMR001372005
    • DB-301333
    • NS00005505
    • Dichloroisopropyl ether [UN2490] [Poison]
    • C19350
    • 1-Chloro-2-(2-chloro-1-methylethoxy)propane #
    • Bis-(2-chloroisopropyl) ether, analytical standard
    • Q2184481
    • Bis-(2-chloro-1-methylethyl) ether 2000 microg/mL in Methanol

  • Applications

    Bis(2-chloro-1-methylethyl) ether (CAS 108-60-1) is used primarily as an industrial solvent and processing aid. In coatings and inks, it provides solvency for resins and additives and helps adjust viscosity and processing properties of the formulation; it is also considered an organic synthesis intermediate for making other specialty chlorinated compounds. In polymer and plastics processing, it may function as a solvent or diluent for production steps and formulation systems. It is used in adhesive formulations as a solvent or processing aid, and in some industrial cleaning formulations for equipment maintenance due to its solvency. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 209.03
    methanol 245.13
    isopropanol 181.0
    water 3.77
    ethyl acetate 275.4
    n-propanol 191.82
    acetone 443.04
    n-butanol 190.59
    acetonitrile 289.35
    DMF 378.91
    toluene 283.77
    isobutanol 157.2
    1,4-dioxane 626.97
    methyl acetate 300.03
    THF 765.11
    2-butanone 344.37
    n-pentanol 150.41
    sec-butanol 191.41
    n-hexane 143.15
    ethylene glycol 65.89
    NMP 674.24
    cyclohexane 344.33
    DMSO 497.67
    n-butyl acetate 282.37
    n-octanol 140.49
    chloroform 1216.89
    n-propyl acetate 212.03
    acetic acid 364.15
    dichloromethane 1016.12
    cyclohexanone 668.08
    propylene glycol 73.0
    isopropyl acetate 171.26
    DMAc 436.35
    2-ethoxyethanol 216.61
    isopentanol 157.5
    n-heptane 156.08
    ethyl formate 186.2
    1,2-dichloroethane 530.46
    n-hexanol 202.98
    2-methoxyethanol 295.75
    isobutyl acetate 157.94
    tetrachloromethane 379.64
    n-pentyl acetate 209.9
    transcutol 681.16
    n-heptanol 109.12
    ethylbenzene 149.11
    MIBK 151.74
    2-propoxyethanol 274.82
    tert-butanol 225.57
    MTBE 270.86
    2-butoxyethanol 166.59
    propionic acid 204.5
    o-xylene 214.07
    formic acid 125.51
    diethyl ether 342.42
    m-xylene 179.17
    p-xylene 220.89
    chlorobenzene 346.37
    dimethyl carbonate 87.25
    n-octane 54.44
    formamide 135.6
    cyclopentanone 633.34
    2-pentanone 246.22
    anisole 221.89
    cyclopentyl methyl ether 453.57
    gamma-butyrolactone 582.13
    1-methoxy-2-propanol 212.59
    pyridine 499.24
    3-pentanone 255.64
    furfural 555.91
    n-dodecane 37.92
    diethylene glycol 213.94
    diisopropyl ether 111.53
    tert-amyl alcohol 214.33
    acetylacetone 294.06
    n-hexadecane 43.02
    acetophenone 229.92
    methyl propionate 211.33
    isopentyl acetate 239.98
    trichloroethylene 958.04
    n-nonanol 126.25
    cyclohexanol 356.53
    benzyl alcohol 183.01
    2-ethylhexanol 178.12
    isooctanol 96.74
    dipropyl ether 292.72
    1,2-dichlorobenzene 329.29
    ethyl lactate 97.18
    propylene carbonate 309.57
    n-methylformamide 175.02
    2-pentanol 137.36
    n-pentane 120.5
    1-propoxy-2-propanol 239.69
    1-methoxy-2-propyl acetate 237.98
    2-(2-methoxypropoxy) propanol 219.99
    mesitylene 122.97
    ε-caprolactone 479.25
    p-cymene 143.74
    epichlorohydrin 581.64
    1,1,1-trichloroethane 647.11
    2-aminoethanol 104.42
    morpholine-4-carbaldehyde 553.76
    sulfolane 714.37
    2,2,4-trimethylpentane 58.45
    2-methyltetrahydrofuran 658.66
    n-hexyl acetate 270.18
    isooctane 32.95
    2-(2-butoxyethoxy)ethanol 256.01
    sec-butyl acetate 151.44
    tert-butyl acetate 199.88
    decalin 107.22
    glycerin 112.87
    diglyme 486.29
    acrylic acid 207.65
    isopropyl myristate 130.63
    n-butyric acid 249.04
    acetyl acetate 224.57
    di(2-ethylhexyl) phthalate 117.98
    ethyl propionate 181.27
    nitromethane 433.41
    1,2-diethoxyethane 358.22
    benzonitrile 286.07
    trioctyl phosphate 87.32
    1-bromopropane 410.5
    gamma-valerolactone 654.34
    n-decanol 95.2
    triethyl phosphate 142.5
    4-methyl-2-pentanol 79.24
    propionitrile 219.38
    vinylene carbonate 300.06
    1,1,2-trichlorotrifluoroethane 452.78
    DMS 199.14
    cumene 109.74
    2-octanol 97.03
    2-hexanone 231.22
    octyl acetate 154.46
    limonene 240.06
    1,2-dimethoxyethane 436.79
    ethyl orthosilicate 143.68
    tributyl phosphate 117.88
    diacetone alcohol 179.52
    N,N-dimethylaniline 184.09
    acrylonitrile 255.62
    aniline 262.92
    1,3-propanediol 143.17
    bromobenzene 377.19
    dibromomethane 776.37
    1,1,2,2-tetrachloroethane 813.48
    2-methyl-cyclohexyl acetate 222.46
    tetrabutyl urea 156.76
    diisobutyl methanol 114.85
    2-phenylethanol 188.6
    styrene 182.15
    dioctyl adipate 195.91
    dimethyl sulfate 159.46
    ethyl butyrate 232.71
    methyl lactate 109.75
    butyl lactate 146.23
    diethyl carbonate 167.54
    propanediol butyl ether 155.14
    triethyl orthoformate 197.46
    p-tert-butyltoluene 137.05
    methyl 4-tert-butylbenzoate 213.78
    morpholine 606.72
    tert-butylamine 186.03
    n-dodecanol 79.38
    dimethoxymethane 243.53
    ethylene carbonate 257.03
    cyrene 223.91
    2-ethoxyethyl acetate 248.03
    2-ethylhexyl acetate 227.95
    1,2,4-trichlorobenzene 421.42
    4-methylpyridine 457.21
    dibutyl ether 259.74
    2,6-dimethyl-4-heptanol 114.85
    DEF 295.5
    dimethyl isosorbide 393.67
    tetrachloroethylene 648.5
    eugenol 185.94
    triacetin 284.43
    span 80 215.64
    1,4-butanediol 78.84
    1,1-dichloroethane 539.43
    2-methyl-1-pentanol 139.81
    methyl formate 163.4
    2-methyl-1-butanol 166.43
    n-decane 65.7
    butyronitrile 218.22
    3,7-dimethyl-1-octanol 144.37
    1-chlorooctane 165.34
    1-chlorotetradecane 75.59
    n-nonane 70.96
    undecane 47.49
    tert-butylcyclohexane 86.16
    cyclooctane 111.72
    cyclopentanol 352.32
    tetrahydropyran 702.92
    tert-amyl methyl ether 241.55
    2,5,8-trioxanonane 375.34
    1-hexene 233.02
    2-isopropoxyethanol 179.54
    2,2,2-trifluoroethanol 166.28
    methyl butyrate 220.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction