Bis (2-Carboxyethylgermanium)sesquioxide

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  • Identifiers

    CAS number
    12758-40-6

    Molecular formula
    C6H10Ge2O7

    SMILES
    C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 55.29%
    Sour 53.0%
    Winey 36.27%
    Caramellic 25.0%
    Buttery 23.97%
    Clean 23.4%
    Sharp 22.9%
    Creamy 21.22%
    Fatty 21.15%
    Burnt 20.72%

     

    Flavor
    Odorless 64.59%
    Sour 45.32%
    Very mild 37.24%
    Mild 31.66%
    Caramellic 28.3%
    Acidic 26.25%
    Yeast 24.95%
    Musty 24.86%
    Nutty 24.68%
    Acetoin 21.89%

     

  • Properties

    pKa est.
    4.93 (weak acid)

    Molecular weight
    339.4 g/mol

    Flash point

    • 178.48 ˚C est.

  • Synonyms

    • Propagermanium
    • 12758-40-6
    • Carboxyethylgermanium sesquioxide
    • BIS (2-CARBOXYETHYLGERMANIUM)SESQUIOXIDE
    • RefChem:18
    • Proxigermanium
    • REPAGERMANIUM
    • BIS(2-CARBOXYETHYLGERMANIUM SESQUIOXIDE)
    • Bis(2-carboxyethylgermanium(IV) sesquioxide)
    • Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-
    • Ge 132
    • 2-Carboxyethylgermasesquioxane
    • Bis(2-carboxyethylgermaniumsesquioxide)
    • 126595-07-1
    • Dipropanoic acid germanium sequioxide
    • 3,3'-(1,3-Dioxo-1,3-digermoxanediyl)dipropionic acid
    • 3,3'-(Germanoic anhydride) dipropanoic acid
    • Bis[2-carboxyethylgermanium(IV)] Sesquioxide
    • 3,3'-(Dioxodigermoxanylene) dipropanoic acid
    • MFCD00049319
    • 2-(Carboxyethyl)germanium sesquioxide
    • 3,3'-(1,3-dioxodigermoxane-1,3-diyl)dipropanoic acid
    • 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid
    • 3-({[(2-carboxyethyl)(oxo)germyl]oxy}(oxo)germyl)propanoic acid
    • 14C-Proxigermanium
    • 3,3'-(1,3-dioxodigermoxane-1,3-diyl)dipropionic acid
    • 3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
    • bis(carboxyethylgermanium) sesquioxide
    • C6H10Ge2O7
    • BETA-CARBOXYETHYLGERMANIUM OXIDE
    • CCRIS 5469
    • Repagermanium [INN]
    • Carboxylethylgermanium sesquioxide
    • EINECS 235-800-0
    • SK 818
    • NSC 267004
    • BRN 4141883
    • UNII-1Q2P9TO9Q7
    • Bis-beta-carboxyethylgermanium sesquioxide
    • Propanoic acid, 3,3'-(oxybis(oxogermylene))bis-
    • Bis(carboxyethylgermanium sesquioxide)
    • Propionic acid, 3,3'-(1,3-dioxodigermoxanylene)di-
    • Propagermanium [INN]
    • Germanate(2-), bis(2-carboxylatoethyl)trioxodi-, dihydrogen
    • MLS000028412
    • 1Q2P9TO9Q7
    • orb1306585
    • SCHEMBL1650976
    • Dihydrogen bis(2-carboxylatoethyl)trioxodigermanate(2-)
    • DTXSID9065316
    • CHEBI:32060
    • XEABSBMNTNXEJM-UHFFFAOYSA-N
    • NSC267004
    • AKOS015903696
    • NSC-267004
    • NCGC00164525-01
    • NCGC00164525-02
    • AS-70115
    • SMR000058405
    • SY057021
    • DB-041866
    • NS00085816
    • ST51007097
    • Propanoic acid,3'-[oxybis(oxogermylene)]bis-
    • D88066
    • A805716
    • Propionic acid,3'-(1,3-dioxodigermoxanylene)di-
    • SR-01000944781
    • Bis(2-carboxyethylgermanium(IV) sesquioxide), 99%
    • Q7250075
    • SR-01000944781-1
    • BRD-K53382462-001-02-0
    • Propanoic acid,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-
    • 3-[[2-carboxyethyl(oxo)germyl]oxy-oxo-germyl]propanoic acid
    • 3-({[(2-CARBOXYETHYL)(OXO)GERMYL]OXY(OXO)GERMYL)PROPANOIC ACID
    • 12758-40-6

  • Applications

    Bis (2-Carboxyethylgermanium)sesquioxide is primarily used as an organogermanium intermediate and a metal chelating agent, enabling participation in organogermanium synthesis. In industry, it is often evaluated as a crosslinking or stabilizing additive in polymer, coating, and ink formulations, with the germanium-containing moieties able to participate in polymer networks or interact with metal oxides. It can serve as a precursor for germanium-containing oxide coatings and dielectric films used in electronics-related applications. Additionally, it can function as a processing aid or dispersant in complex formulations due to its polar carboxylate groups (CAS 12758-40-6).

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 27.42
    methanol 36.34
    isopropanol 22.73
    water 4.67
    ethyl acetate 33.13
    n-propanol 20.68
    acetone 79.37
    n-butanol 16.43
    acetonitrile 33.1
    DMF 316.93
    toluene 9.46
    isobutanol 14.44
    1,4-dioxane 71.51
    methyl acetate 50.66
    THF 111.48
    2-butanone 54.72
    n-pentanol 14.33
    sec-butanol 22.58
    n-hexane 2.38
    ethylene glycol 14.56
    NMP 234.15
    cyclohexane 4.89
    DMSO 417.78
    n-butyl acetate 23.57
    n-octanol 16.72
    chloroform 33.72
    n-propyl acetate 24.37
    acetic acid 36.06
    dichloromethane 47.76
    cyclohexanone 56.23
    propylene glycol 13.76
    isopropyl acetate 23.45
    DMAc 302.14
    2-ethoxyethanol 67.08
    isopentanol 15.16
    n-heptane 2.71
    ethyl formate 40.3
    1,2-dichloroethane 43.06
    n-hexanol 12.97
    2-methoxyethanol 104.37
    isobutyl acetate 10.9
    tetrachloromethane 5.98
    n-pentyl acetate 20.81
    transcutol 93.42
    n-heptanol 10.69
    ethylbenzene 7.41
    MIBK 21.9
    2-propoxyethanol 46.98
    tert-butanol 34.33
    MTBE 35.88
    2-butoxyethanol 29.79
    propionic acid 22.75
    o-xylene 12.6
    formic acid 38.99
    diethyl ether 35.65
    m-xylene 7.19
    p-xylene 8.39
    chlorobenzene 12.64
    dimethyl carbonate 38.38
    n-octane 1.86
    formamide 85.89
    cyclopentanone 77.29
    2-pentanone 35.93
    anisole 34.38
    cyclopentyl methyl ether 36.82
    gamma-butyrolactone 88.85
    1-methoxy-2-propanol 67.06
    pyridine 41.03
    3-pentanone 37.1
    furfural 109.64
    n-dodecane 1.79
    diethylene glycol 52.74
    diisopropyl ether 10.15
    tert-amyl alcohol 32.66
    acetylacetone 60.48
    n-hexadecane 1.98
    acetophenone 39.04
    methyl propionate 40.99
    isopentyl acetate 20.36
    trichloroethylene 50.37
    n-nonanol 16.16
    cyclohexanol 18.47
    benzyl alcohol 23.41
    2-ethylhexanol 10.74
    isooctanol 8.93
    dipropyl ether 16.92
    1,2-dichlorobenzene 17.3
    ethyl lactate 22.96
    propylene carbonate 44.71
    n-methylformamide 92.75
    2-pentanol 13.71
    n-pentane 2.91
    1-propoxy-2-propanol 35.41
    1-methoxy-2-propyl acetate 38.29
    2-(2-methoxypropoxy) propanol 55.25
    mesitylene 6.02
    ε-caprolactone 49.74
    p-cymene 7.91
    epichlorohydrin 91.68
    1,1,1-trichloroethane 20.42
    2-aminoethanol 23.88
    morpholine-4-carbaldehyde 182.29
    sulfolane 164.32
    2,2,4-trimethylpentane 2.0
    2-methyltetrahydrofuran 59.44
    n-hexyl acetate 27.13
    isooctane 0.86
    2-(2-butoxyethoxy)ethanol 52.58
    sec-butyl acetate 16.06
    tert-butyl acetate 29.64
    decalin 2.56
    glycerin 29.94
    diglyme 103.25
    acrylic acid 24.23
    isopropyl myristate 14.69
    n-butyric acid 24.06
    acetyl acetate 24.17
    di(2-ethylhexyl) phthalate 19.25
    ethyl propionate 26.08
    nitromethane 115.38
    1,2-diethoxyethane 38.87
    benzonitrile 22.43
    trioctyl phosphate 13.35
    1-bromopropane 19.67
    gamma-valerolactone 122.24
    n-decanol 12.89
    triethyl phosphate 21.77
    4-methyl-2-pentanol 8.67
    propionitrile 22.18
    vinylene carbonate 40.45
    1,1,2-trichlorotrifluoroethane 76.19
    DMS 28.41
    cumene 6.31
    2-octanol 9.83
    2-hexanone 28.63
    octyl acetate 20.16
    limonene 12.05
    1,2-dimethoxyethane 146.27
    ethyl orthosilicate 20.26
    tributyl phosphate 16.53
    diacetone alcohol 42.14
    N,N-dimethylaniline 35.55
    acrylonitrile 29.39
    aniline 19.7
    1,3-propanediol 30.09
    bromobenzene 10.57
    dibromomethane 28.34
    1,1,2,2-tetrachloroethane 52.42
    2-methyl-cyclohexyl acetate 24.52
    tetrabutyl urea 33.64
    diisobutyl methanol 8.77
    2-phenylethanol 21.68
    styrene 9.11
    dioctyl adipate 24.71
    dimethyl sulfate 99.08
    ethyl butyrate 23.37
    methyl lactate 37.97
    butyl lactate 21.7
    diethyl carbonate 20.91
    propanediol butyl ether 29.24
    triethyl orthoformate 23.42
    p-tert-butyltoluene 8.35
    methyl 4-tert-butylbenzoate 41.75
    morpholine 78.63
    tert-butylamine 19.64
    n-dodecanol 10.41
    dimethoxymethane 135.94
    ethylene carbonate 31.45
    cyrene 61.79
    2-ethoxyethyl acetate 34.34
    2-ethylhexyl acetate 17.41
    1,2,4-trichlorobenzene 23.22
    4-methylpyridine 43.18
    dibutyl ether 16.97
    2,6-dimethyl-4-heptanol 8.77
    DEF 82.16
    dimethyl isosorbide 85.53
    tetrachloroethylene 29.81
    eugenol 40.9
    triacetin 36.47
    span 80 32.03
    1,4-butanediol 15.9
    1,1-dichloroethane 23.67
    2-methyl-1-pentanol 13.87
    methyl formate 81.64
    2-methyl-1-butanol 15.91
    n-decane 2.78
    butyronitrile 20.47
    3,7-dimethyl-1-octanol 14.86
    1-chlorooctane 9.84
    1-chlorotetradecane 5.05
    n-nonane 2.64
    undecane 2.17
    tert-butylcyclohexane 2.1
    cyclooctane 2.2
    cyclopentanol 24.52
    tetrahydropyran 36.77
    tert-amyl methyl ether 36.35
    2,5,8-trioxanonane 91.8
    1-hexene 6.38
    2-isopropoxyethanol 39.1
    2,2,2-trifluoroethanol 29.25
    methyl butyrate 34.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction