Biphenylhydroxamic acid

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  • Identifiers

    CAS number
    106359-54-0

    Molecular formula
    C13H11NO2

    SMILES
    C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NO

    Safety labels

  • Odor profile

    Fragrance
    Sweet 40.81%
    Honey 38.78%
    Floral 36.6%
    Fruity 35.38%
    Balsamic 34.91%
    Bitter 32.36%
    Spicy 30.48%
    Almond 28.87%
    Rose 28.73%
    Powdery 27.21%

     

    Flavor
    Bitter 43.96%
    Balsam 39.68%
    Sweet 36.16%
    Honey 33.2%
    Fruity 30.58%
    Odorless 30.19%
    Mild 30.15%
    Rose 26.07%
    Powdery 25.97%
    Balsamic 25.8%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    9.13 (weak base)

    Molecular weight
    213.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    482°C

    Flash point

    • 198.65 ˚C est.

  • Synonyms

    • Biphenylhydroxamic acid
    • UNII-R3GRG20IPQ
    • R3GRG20IPQ
    • 106359-54-0
    • (1,1'-Biphenyl)-4-carboxamide, N-hydroxy-
    • Biphenyl-4-carboxylic acid hydroxyamide
    • CHEMBL154585
    • N-Hydroxy[1,1'-biphenyl]-4-carboxamide
    • 4-biphenyl hydroxamic acid
    • SCHEMBL2143958
    • SCHEMBL8496406
    • DTXSID00147585
    • BDBM50015086
    • DB-387702
    • Q27287742
    • 106359-54-0

  • Applications

    Biphenylhydroxamic acid (CAS 106359-54-0) is used as a chelating agent and metal-ion ligand in analytical chemistry and catalysis, enabling sequestration of metal ions and formation of coordination complexes. It is commonly evaluated as an intermediate in organic synthesis and in the development of metal-containing complexes for materials and catalytic applications. In coatings and inks, it may serve as a metal-chelating additive to improve pigment stability and substrate compatibility; in polymer and plastics formulations, it has been explored as a stabilizing or metal-binding additive; and in electronic materials and surface treatment, it can act as a reagent for surface modification and the preparation of metal-containing coatings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.54
    methanol 15.88
    isopropanol 7.94
    water 0.11
    ethyl acetate 26.25
    n-propanol 10.31
    acetone 37.3
    n-butanol 8.54
    acetonitrile 12.07
    DMF 125.89
    toluene 5.85
    isobutanol 6.04
    1,4-dioxane 36.16
    methyl acetate 30.47
    THF 72.71
    2-butanone 41.67
    n-pentanol 10.33
    sec-butanol 9.11
    n-hexane 0.19
    ethylene glycol 13.04
    NMP 52.86
    cyclohexane 0.08
    DMSO 169.52
    n-butyl acetate 23.3
    n-octanol 3.41
    chloroform 18.08
    n-propyl acetate 23.51
    acetic acid 28.08
    dichloromethane 17.18
    cyclohexanone 32.86
    propylene glycol 13.52
    isopropyl acetate 23.25
    DMAc 154.16
    2-ethoxyethanol 50.02
    isopentanol 11.32
    n-heptane 0.33
    ethyl formate 11.98
    1,2-dichloroethane 31.67
    n-hexanol 11.29
    2-methoxyethanol 64.99
    isobutyl acetate 14.06
    tetrachloromethane 1.66
    n-pentyl acetate 12.23
    transcutol 373.91
    n-heptanol 6.55
    ethylbenzene 6.88
    MIBK 27.31
    2-propoxyethanol 45.43
    tert-butanol 20.06
    MTBE 20.32
    2-butoxyethanol 27.96
    propionic acid 19.25
    o-xylene 6.93
    formic acid 23.33
    diethyl ether 15.8
    m-xylene 6.24
    p-xylene 6.44
    chlorobenzene 9.01
    dimethyl carbonate 30.03
    n-octane 0.18
    formamide 84.13
    cyclopentanone 62.71
    2-pentanone 29.09
    anisole 31.01
    cyclopentyl methyl ether 19.56
    gamma-butyrolactone 77.92
    1-methoxy-2-propanol 51.25
    pyridine 30.51
    3-pentanone 24.05
    furfural 63.42
    n-dodecane 0.22
    diethylene glycol 52.08
    diisopropyl ether 6.28
    tert-amyl alcohol 18.92
    acetylacetone 56.61
    n-hexadecane 0.25
    acetophenone 31.7
    methyl propionate 30.5
    isopentyl acetate 24.67
    trichloroethylene 70.76
    n-nonanol 4.2
    cyclohexanol 6.44
    benzyl alcohol 21.41
    2-ethylhexanol 8.1
    isooctanol 6.57
    dipropyl ether 11.73
    1,2-dichlorobenzene 12.73
    ethyl lactate 21.68
    propylene carbonate 30.93
    n-methylformamide 42.27
    2-pentanol 8.18
    n-pentane 0.11
    1-propoxy-2-propanol 34.69
    1-methoxy-2-propyl acetate 49.24
    2-(2-methoxypropoxy) propanol 46.01
    mesitylene 4.34
    ε-caprolactone 33.32
    p-cymene 5.67
    epichlorohydrin 101.15
    1,1,1-trichloroethane 14.35
    2-aminoethanol 20.72
    morpholine-4-carbaldehyde 77.72
    sulfolane 115.34
    2,2,4-trimethylpentane 0.53
    2-methyltetrahydrofuran 27.23
    n-hexyl acetate 13.7
    isooctane 0.49
    2-(2-butoxyethoxy)ethanol 65.42
    sec-butyl acetate 20.21
    tert-butyl acetate 39.43
    decalin 0.53
    glycerin 35.33
    diglyme 137.02
    acrylic acid 24.48
    isopropyl myristate 7.63
    n-butyric acid 19.58
    acetyl acetate 18.93
    di(2-ethylhexyl) phthalate 9.12
    ethyl propionate 24.57
    nitromethane 89.5
    1,2-diethoxyethane 56.84
    benzonitrile 15.52
    trioctyl phosphate 5.86
    1-bromopropane 6.51
    gamma-valerolactone 85.02
    n-decanol 3.57
    triethyl phosphate 15.25
    4-methyl-2-pentanol 8.58
    propionitrile 12.67
    vinylene carbonate 27.23
    1,1,2-trichlorotrifluoroethane 82.37
    DMS 31.64
    cumene 5.59
    2-octanol 3.7
    2-hexanone 25.11
    octyl acetate 8.29
    limonene 6.79
    1,2-dimethoxyethane 82.59
    ethyl orthosilicate 14.84
    tributyl phosphate 8.44
    diacetone alcohol 56.78
    N,N-dimethylaniline 20.28
    acrylonitrile 24.45
    aniline 14.97
    1,3-propanediol 24.45
    bromobenzene 7.14
    dibromomethane 7.69
    1,1,2,2-tetrachloroethane 58.0
    2-methyl-cyclohexyl acetate 19.52
    tetrabutyl urea 12.37
    diisobutyl methanol 7.68
    2-phenylethanol 20.78
    styrene 7.41
    dioctyl adipate 14.58
    dimethyl sulfate 63.64
    ethyl butyrate 22.12
    methyl lactate 31.98
    butyl lactate 17.25
    diethyl carbonate 17.08
    propanediol butyl ether 24.25
    triethyl orthoformate 18.48
    p-tert-butyltoluene 5.7
    methyl 4-tert-butylbenzoate 29.38
    morpholine 43.68
    tert-butylamine 9.05
    n-dodecanol 2.96
    dimethoxymethane 76.87
    ethylene carbonate 17.89
    cyrene 36.76
    2-ethoxyethyl acetate 34.54
    2-ethylhexyl acetate 17.35
    1,2,4-trichlorobenzene 18.97
    4-methylpyridine 21.19
    dibutyl ether 8.17
    2,6-dimethyl-4-heptanol 7.68
    DEF 38.67
    dimethyl isosorbide 75.16
    tetrachloroethylene 29.5
    eugenol 32.6
    triacetin 31.42
    span 80 25.12
    1,4-butanediol 11.6
    1,1-dichloroethane 12.18
    2-methyl-1-pentanol 13.39
    methyl formate 28.87
    2-methyl-1-butanol 9.3
    n-decane 0.3
    butyronitrile 8.76
    3,7-dimethyl-1-octanol 6.4
    1-chlorooctane 2.09
    1-chlorotetradecane 1.14
    n-nonane 0.23
    undecane 0.26
    tert-butylcyclohexane 0.74
    cyclooctane 0.07
    cyclopentanol 7.73
    tetrahydropyran 16.44
    tert-amyl methyl ether 19.27
    2,5,8-trioxanonane 92.09
    1-hexene 2.09
    2-isopropoxyethanol 37.41
    2,2,2-trifluoroethanol 17.85
    methyl butyrate 27.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction