beta-D-fructose

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  • Identifiers

    CAS number
    53188-23-1

    Molecular formula
    C6H12O6

    SMILES
    C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 64.16%
    Sweet 61.07%
    Caramellic 26.75%
    Woody 21.08%
    Alcoholic 20.41%
    Clean 18.1%
    Bitter 16.14%
    Creamy 15.43%
    Vanilla 15.29%
    Milky 15.18%

     

    Flavor
    Sweet 85.89%
    Odorless 62.41%
    Bitter 50.97%
    Sweet-like 32.68%
    Alcoholic 24.31%
    Very slight 23.26%
    Cauliflower 22.43%
    Vanilla 20.87%
    Soup 20.85%
    Alkaline 20.48%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.3

    pKa est.
    5.62 (weak acid)

    Molecular weight
    180.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    777°C

    Melting point expt.

    • 119 - 122 °C

    Flash point

    • 224.51 ˚C est.

    Solubility expt.

    • 778 mg/mL at 20 °C

  • Synonyms

    • beta-D-fructofuranose
    • beta-Levulose
    • beta-D-Fructose
    • beta-Fruit sugar
    • beta-D-Arabino-hexulose
    • 53188-23-1
    • B986VTP17J
    • CHEBI:28645
    • DTXSID60859011
    • RefChem:937011
    • GlyTouCan:G23778LQ
    • BETA-D.-FRUCTOFURANOSE
    • DTXCID103081
    • DTXSID20273991
    • G23778LQ
    • 470-23-5
    • b-D-Fructofuranose
    • Fructooligosaccharides
    • (2R,3S,4S,5R)-2,5-bis(hydroxymethyl)tetrahydrofuran-2,3,4-triol
    • 308066-66-2
    • MFCD20488856
    • |A-D-fructofuranose
    • delta-Fructose
    • Fructose CRS
    • Beta-delta-fructose
    • delta-(-)-Fructose
    • beta-D-Fructofuranoside
    • Lactulose Impurity 31
    • 2x7x
    • Fructose, furanose form
    • Beta-delta-fructofuranose
    • Beta-delta-arabino-hexulose
    • SCHEMBL3966
    • (2->1)-beta-D-fructan
    • (2,1-beta-D-Fructosyl)n
    • UNII-B986VTP17J
    • CHEBI:29084
    • .BETA.-D.-FRUCTOFURANOSE
    • Pharmakon1600-01301021
    • BDBM50249032
    • EBC-71024
    • NSC760385
    • AKOS026676646
    • NCGC00248823-01
    • SY356361
    • NS00015232
    • ST50407024
    • beta-D-fructofuranose (closed ring structure)
    • C02336
    • G67099
    • Q27103808
    • F8889-8688
    • (2R,3S,4S,5R)-2,5-Bis(hydroxymethyl)-oxolane-2,3,4-triol
    • 308066-66-2

  • Applications

    beta-D-fructose (CAS 53188-23-1) has broad practical use due to high solubility, humectant properties, and sweetness; in food processing it is used as a sweetener and syrup component and serves as a carbon source for fermentation processes in beverage production and other fermentative products; in cosmetics and personal care it is commonly used as a humectant and moisture-retaining ingredient to help stabilize hydration and texture in formulations; in pharmaceuticals it can function as a sweetening excipient or a solvent base for oral liquids and syrups; in industrial manufacturing and materials it can act as a carbon source for fermentative production of bio-based chemicals and polymers; formulation and regulatory considerations apply, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 41.28
    methanol 238.33
    isopropanol 15.01
    water 2021.9
    ethyl acetate 6.1
    n-propanol 14.53
    acetone 10.87
    n-butanol 11.82
    acetonitrile 5.4
    DMF 566.63
    toluene 1.07
    isobutanol 7.49
    1,4-dioxane 34.07
    methyl acetate 3.81
    THF 21.06
    2-butanone 6.42
    n-pentanol 8.57
    sec-butanol 12.57
    n-hexane 0.49
    ethylene glycol 425.61
    NMP 238.99
    cyclohexane 2.07
    DMSO 1630.3
    n-butyl acetate 2.45
    n-octanol 5.55
    chloroform 2.64
    n-propyl acetate 2.35
    acetic acid 32.81
    dichloromethane 5.53
    cyclohexanone 13.45
    propylene glycol 120.45
    isopropyl acetate 4.15
    DMAc 224.66
    2-ethoxyethanol 91.22
    isopentanol 7.35
    n-heptane 2.06
    ethyl formate 6.44
    1,2-dichloroethane 6.16
    n-hexanol 6.87
    2-methoxyethanol 234.03
    isobutyl acetate 1.01
    tetrachloromethane 1.53
    n-pentyl acetate 2.7
    transcutol 46.42
    n-heptanol 7.35
    ethylbenzene 0.99
    MIBK 4.47
    2-propoxyethanol 41.57
    tert-butanol 12.69
    MTBE 4.15
    2-butoxyethanol 28.19
    propionic acid 14.1
    o-xylene 2.44
    formic acid 643.31
    diethyl ether 5.65
    m-xylene 1.88
    p-xylene 1.07
    chlorobenzene 0.88
    dimethyl carbonate 15.54
    n-octane 1.02
    formamide 501.67
    cyclopentanone 16.22
    2-pentanone 6.8
    anisole 3.45
    cyclopentyl methyl ether 10.08
    gamma-butyrolactone 24.99
    1-methoxy-2-propanol 100.53
    pyridine 6.83
    3-pentanone 6.55
    furfural 38.14
    n-dodecane 0.57
    diethylene glycol 139.6
    diisopropyl ether 2.05
    tert-amyl alcohol 11.36
    acetylacetone 14.39
    n-hexadecane 0.62
    acetophenone 5.0
    methyl propionate 11.48
    isopentyl acetate 1.79
    trichloroethylene 5.51
    n-nonanol 5.07
    cyclohexanol 13.86
    benzyl alcohol 8.69
    2-ethylhexanol 3.68
    isooctanol 5.03
    dipropyl ether 5.42
    1,2-dichlorobenzene 1.48
    ethyl lactate 12.41
    propylene carbonate 8.59
    n-methylformamide 173.27
    2-pentanol 7.56
    n-pentane 0.98
    1-propoxy-2-propanol 21.28
    1-methoxy-2-propyl acetate 9.8
    2-(2-methoxypropoxy) propanol 19.6
    mesitylene 1.97
    ε-caprolactone 13.43
    p-cymene 1.83
    epichlorohydrin 19.92
    1,1,1-trichloroethane 1.25
    2-aminoethanol 195.32
    morpholine-4-carbaldehyde 196.74
    sulfolane 128.78
    2,2,4-trimethylpentane 0.54
    2-methyltetrahydrofuran 9.16
    n-hexyl acetate 3.29
    isooctane 0.36
    2-(2-butoxyethoxy)ethanol 28.0
    sec-butyl acetate 1.6
    tert-butyl acetate 4.52
    decalin 0.65
    glycerin 394.08
    diglyme 57.26
    acrylic acid 24.93
    isopropyl myristate 1.63
    n-butyric acid 11.58
    acetyl acetate 3.96
    di(2-ethylhexyl) phthalate 3.02
    ethyl propionate 3.57
    nitromethane 60.62
    1,2-diethoxyethane 6.82
    benzonitrile 3.05
    trioctyl phosphate 3.01
    1-bromopropane 1.77
    gamma-valerolactone 57.35
    n-decanol 3.84
    triethyl phosphate 3.54
    4-methyl-2-pentanol 4.13
    propionitrile 3.17
    vinylene carbonate 9.2
    1,1,2-trichlorotrifluoroethane 73.21
    DMS 4.7
    cumene 1.03
    2-octanol 4.16
    2-hexanone 2.73
    octyl acetate 2.4
    limonene 2.97
    1,2-dimethoxyethane 48.79
    ethyl orthosilicate 3.33
    tributyl phosphate 2.13
    diacetone alcohol 17.82
    N,N-dimethylaniline 5.93
    acrylonitrile 7.32
    aniline 4.53
    1,3-propanediol 117.81
    bromobenzene 0.68
    dibromomethane 2.69
    1,1,2,2-tetrachloroethane 7.23
    2-methyl-cyclohexyl acetate 2.43
    tetrabutyl urea 5.68
    diisobutyl methanol 3.29
    2-phenylethanol 6.12
    styrene 0.87
    dioctyl adipate 2.93
    dimethyl sulfate 58.05
    ethyl butyrate 3.31
    methyl lactate 46.29
    butyl lactate 6.19
    diethyl carbonate 2.1
    propanediol butyl ether 28.58
    triethyl orthoformate 3.96
    p-tert-butyltoluene 1.88
    methyl 4-tert-butylbenzoate 10.53
    morpholine 49.01
    tert-butylamine 5.46
    n-dodecanol 3.03
    dimethoxymethane 90.11
    ethylene carbonate 7.4
    cyrene 45.09
    2-ethoxyethyl acetate 5.25
    2-ethylhexyl acetate 1.51
    1,2,4-trichlorobenzene 1.85
    4-methylpyridine 5.04
    dibutyl ether 2.43
    2,6-dimethyl-4-heptanol 3.29
    DEF 43.48
    dimethyl isosorbide 27.94
    tetrachloroethylene 7.23
    eugenol 15.03
    triacetin 6.33
    span 80 16.35
    1,4-butanediol 64.73
    1,1-dichloroethane 1.7
    2-methyl-1-pentanol 5.2
    methyl formate 70.22
    2-methyl-1-butanol 8.18
    n-decane 0.95
    butyronitrile 3.44
    3,7-dimethyl-1-octanol 3.45
    1-chlorooctane 1.71
    1-chlorotetradecane 0.82
    n-nonane 0.99
    undecane 0.71
    tert-butylcyclohexane 0.38
    cyclooctane 1.51
    cyclopentanol 15.43
    tetrahydropyran 8.53
    tert-amyl methyl ether 5.79
    2,5,8-trioxanonane 46.44
    1-hexene 0.81
    2-isopropoxyethanol 31.21
    2,2,2-trifluoroethanol 65.27
    methyl butyrate 4.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction