Beta-Boswellic Acid

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  • Identifiers

    CAS number
    631-69-6

    Molecular formula
    C30H48O3

    SMILES
    C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)O)C)C)[C@@H]2[C@H]1C)C)C

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  • Odor profile

    Fragrance
    Woody 85.18%
    Amber 55.07%
    Dry 49.52%
    Cedar 46.95%
    Sandalwood 45.77%
    Balsamic 42.73%
    Musk 38.14%
    Spicy 35.14%
    Vetiver 34.45%
    Sweet 31.07%

     

    Flavor
    Woody 64.41%
    Camphor 45.65%
    Pine 43.8%
    Balsam 41.38%
    Herbal 39.63%
    Sweet 39.45%
    Earthy 34.25%
    Dry 30.04%
    Fir needle 28.39%
    Spicy 28.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.3

    pKa est.
    5.95 (weak acid)

    Molecular weight
    456.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    482°C

    Flash point

    • 264.13 ˚C est.

  • Synonyms

    • beta-Boswellic acid
    • Boswellic acid
    • 631-69-6
    • (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid
    • B252M1YO2V
    • DTXSID2057578
    • (4R)-3alpha-Hydroxyurs-12-en-24-oic acid
    • Urs-12-en-23-oic acid, 3-hydroxy-, (3alpha,4beta)-
    • 12-Ursene-3,24-diol
    • RefChem:119215
    • DTXCID2020428
    • CHEMBL267225
    • ss-Boswellic Acid
    • (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
    • MFCD04039448
    • UNII-B252M1YO2V
    • NBGQZFQREPIKMG-PONOSELZSA-N
    • yena-Boswellic acid
    • Urs-12-en-24-oic acid, 3.alpha.-hydroxy-
    • MLS000697685
    • .BETA.-BOSWELLIC ACID
    • |A-Boswellic acid (Standard)
    • SCHEMBL4385785
    • HY-N2513R
    • CHEBI:192014
    • Urs-12-en-23-oic acid, 3-hydroxy-, (3.alpha.,4.beta.)-
    • HY-N2513
    • .BETA.-BOSWELLIC ACID [MI]
    • BDBM50241260
    • AKOS015897120
    • 3alpha-Hydroxyurs-12-en-24-oic acid
    • EBC-618511
    • FB42754
    • LMPR0106180011
    • beta-Boswellic acid, analytical standard
    • NCGC00247633-01
    • AC-30252
    • SMR000445587
    • CS-0022784
    • (3alpha,4beta)-3-hydroxy-Urs-12-en-23-oate
    • 3.ALPHA.-HYDROXYURS-12-EN-24-OIC ACID
    • 631B696
    • (3alpha,4beta)-3-hydroxy-Urs-12-en-23-oic acid
    • Q27274271
    • .BETA.-BOSWELLIC ACID (CONSTITUENT OF BOSWELLIA SERRATA) [DSC]
    • 631-69-6

  • Applications

    Beta-Boswellic Acid, a pentacyclic triterpene isolated from Boswellia serrata (CAS 631-69-6), is primarily encountered in cosmetic and pharmaceutical research contexts. In cosmetics and personal care, it is evaluated as a specialty bioactive ingredient for skin-care formulations. In pharmaceutical and biomedical research, it can serve as a lead scaffold and a potential intermediate for semi-synthetic transformations to related boswellic acids. In analytical and quality-control workflows, it is used as a reference standard for GC/LC methods to characterize Boswellia-derived materials. It may also be used as a chemical precursor or starting material in natural product synthesis and derivative chemistry in R&D programs.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.27
    methanol 8.43
    isopropanol 10.23
    water 0.0
    ethyl acetate 3.63
    n-propanol 15.13
    acetone 6.7
    n-butanol 12.66
    acetonitrile 1.63
    DMF 36.85
    toluene 6.47
    isobutanol 9.93
    1,4-dioxane 21.48
    methyl acetate 3.34
    THF 43.46
    2-butanone 8.79
    n-pentanol 8.67
    sec-butanol 6.22
    n-hexane 0.34
    ethylene glycol 0.89
    NMP 18.63
    cyclohexane 0.34
    DMSO 9.95
    n-butyl acetate 5.22
    n-octanol 4.52
    chloroform 12.73
    n-propyl acetate 3.46
    acetic acid 3.15
    dichloromethane 6.61
    cyclohexanone 12.6
    propylene glycol 2.49
    isopropyl acetate 4.1
    DMAc 21.98
    2-ethoxyethanol 12.62
    isopentanol 8.11
    n-heptane 0.3
    ethyl formate 2.29
    1,2-dichloroethane 4.87
    n-hexanol 9.89
    2-methoxyethanol 18.37
    isobutyl acetate 3.77
    tetrachloromethane 2.17
    n-pentyl acetate 8.57
    transcutol 21.42
    n-heptanol 8.03
    ethylbenzene 3.17
    MIBK 5.77
    2-propoxyethanol 32.14
    tert-butanol 6.82
    MTBE 5.24
    2-butoxyethanol 21.72
    propionic acid 3.25
    o-xylene 3.38
    formic acid 1.42
    diethyl ether 6.8
    m-xylene 4.66
    p-xylene 3.31
    chlorobenzene 4.76
    dimethyl carbonate 3.43
    n-octane 0.14
    formamide 2.25
    cyclopentanone 17.26
    2-pentanone 7.48
    anisole 7.08
    cyclopentyl methyl ether 10.48
    gamma-butyrolactone 10.88
    1-methoxy-2-propanol 22.18
    pyridine 15.63
    3-pentanone 5.69
    furfural 9.51
    n-dodecane 0.06
    diethylene glycol 12.87
    diisopropyl ether 1.78
    tert-amyl alcohol 4.53
    acetylacetone 6.7
    n-hexadecane 0.07
    acetophenone 6.43
    methyl propionate 5.21
    isopentyl acetate 6.51
    trichloroethylene 10.3
    n-nonanol 5.11
    cyclohexanol 5.5
    benzyl alcohol 7.81
    2-ethylhexanol 3.98
    isooctanol 6.07
    dipropyl ether 4.76
    1,2-dichlorobenzene 4.2
    ethyl lactate 3.29
    propylene carbonate 4.29
    n-methylformamide 8.06
    2-pentanol 5.25
    n-pentane 0.38
    1-propoxy-2-propanol 21.16
    1-methoxy-2-propyl acetate 11.18
    2-(2-methoxypropoxy) propanol 11.9
    mesitylene 2.59
    ε-caprolactone 9.44
    p-cymene 2.26
    epichlorohydrin 15.3
    1,1,1-trichloroethane 4.1
    2-aminoethanol 4.57
    morpholine-4-carbaldehyde 26.32
    sulfolane 13.53
    2,2,4-trimethylpentane 0.25
    2-methyltetrahydrofuran 11.11
    n-hexyl acetate 8.64
    isooctane 0.26
    2-(2-butoxyethoxy)ethanol 17.09
    sec-butyl acetate 2.92
    tert-butyl acetate 5.26
    decalin 0.35
    glycerin 4.06
    diglyme 25.6
    acrylic acid 2.74
    isopropyl myristate 2.49
    n-butyric acid 5.97
    acetyl acetate 2.48
    di(2-ethylhexyl) phthalate 4.91
    ethyl propionate 3.17
    nitromethane 4.51
    1,2-diethoxyethane 7.68
    benzonitrile 4.71
    trioctyl phosphate 3.37
    1-bromopropane 3.36
    gamma-valerolactone 28.2
    n-decanol 2.56
    triethyl phosphate 2.53
    4-methyl-2-pentanol 3.73
    propionitrile 3.76
    vinylene carbonate 4.84
    1,1,2-trichlorotrifluoroethane 11.28
    DMS 5.05
    cumene 2.22
    2-octanol 3.62
    2-hexanone 6.11
    octyl acetate 3.68
    limonene 2.35
    1,2-dimethoxyethane 17.06
    ethyl orthosilicate 2.99
    tributyl phosphate 2.58
    diacetone alcohol 8.12
    N,N-dimethylaniline 6.1
    acrylonitrile 4.11
    aniline 6.95
    1,3-propanediol 9.15
    bromobenzene 4.49
    dibromomethane 4.73
    1,1,2,2-tetrachloroethane 9.62
    2-methyl-cyclohexyl acetate 5.08
    tetrabutyl urea 4.6
    diisobutyl methanol 2.5
    2-phenylethanol 10.73
    styrene 3.01
    dioctyl adipate 4.38
    dimethyl sulfate 4.98
    ethyl butyrate 3.52
    methyl lactate 4.82
    butyl lactate 9.17
    diethyl carbonate 2.08
    propanediol butyl ether 14.22
    triethyl orthoformate 4.39
    p-tert-butyltoluene 2.38
    methyl 4-tert-butylbenzoate 11.46
    morpholine 30.37
    tert-butylamine 3.32
    n-dodecanol 1.24
    dimethoxymethane 24.82
    ethylene carbonate 4.12
    cyrene 11.83
    2-ethoxyethyl acetate 12.47
    2-ethylhexyl acetate 5.06
    1,2,4-trichlorobenzene 6.14
    4-methylpyridine 11.93
    dibutyl ether 2.27
    2,6-dimethyl-4-heptanol 2.5
    DEF 7.97
    dimethyl isosorbide 17.96
    tetrachloroethylene 7.07
    eugenol 13.29
    triacetin 6.87
    span 80 10.6
    1,4-butanediol 3.64
    1,1-dichloroethane 4.1
    2-methyl-1-pentanol 5.54
    methyl formate 4.11
    2-methyl-1-butanol 7.33
    n-decane 0.18
    butyronitrile 4.27
    3,7-dimethyl-1-octanol 3.33
    1-chlorooctane 1.23
    1-chlorotetradecane 0.27
    n-nonane 0.16
    undecane 0.1
    tert-butylcyclohexane 0.36
    cyclooctane 0.19
    cyclopentanol 7.24
    tetrahydropyran 15.02
    tert-amyl methyl ether 3.59
    2,5,8-trioxanonane 15.35
    1-hexene 1.51
    2-isopropoxyethanol 9.14
    2,2,2-trifluoroethanol 1.33
    methyl butyrate 4.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction