Benzylhexadecyldimethylammonium chloride

Overview IFRA Request a quote

  • Identifiers

    CAS number
    122-18-9

    Molecular formula
    C25H46ClN

    SMILES
    CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1.[Cl-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 71.61%
    Fatty 43.05%
    Oily 36.95%
    Balsamic 22.85%
    Fishy 20.8%
    Burnt 20.59%
    Green 20.34%
    Sweet 20.13%
    Animal 19.32%
    Meaty 19.27%

     

    Flavor
    Waxy 26.85%
    Bland 25.4%
    Mild 24.9%
    Delicate 21.31%
    Slightly waxy 20.26%
    Alkane 19.96%
    Diterpene 19.81%
    Low 19.19%
    Oriental 19.08%
    Beer 18.62%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.93 (neutral)

    Molecular weight
    396.1 g/mol

    Flash point

    • 123.77 ˚C est.

  • Synonyms

    • 122-18-9
    • Cetalkonium chloride
    • Benzyldimethylhexadecylammonium chloride
    • Cetyl zephiran
    • Banicol
    • Acinol
    • Cdbac
    • Bicetonium
    • Zettyn
    • Cetyldimethylbenzylammonium chloride
    • Benzaletas
    • Tetraseptan
    • Baktonium
    • Cetylon
    • Cetol
    • Dmcbac
    • Spilan
    • Benzylhexadecyldimethylammonium chloride
    • Ammonyx G
    • Dehyquart CBB
    • Benzylcetyldimethylammonium chloride
    • Cloruro de cetalconio
    • Dehyquart CDB
    • Chlorure de cetalkonium
    • Cetylbenzyldimethylammonium chloride
    • Dimethylbenzylhexadecylammonium chloride
    • Win 357
    • Dimethylbenzylcetylammonium chloride
    • Cetalconio cloruro
    • Acquat CDAC
    • Cetalkonii chloridum
    • Benzyldimethylcetylammonium chloride
    • Hexadecylbenzyldimethylammonium chloride
    • Ammonium, benzylhexadecyldimethyl-, chloride
    • N-Hexadecyl-N,N-dimethylbenzenemethanaminium chloride
    • NSC-32942
    • Cetyl dimethyl benzyl ammonium chloride
    • Benzyl hexadecyl dimethyl ammonium chloride
    • 85474O1N9D
    • Benzyldimethyl-n-hexadecylammonium chloride
    • NSC32942
    • cAtalkonium (cation)
    • RefChem:575293
    • 204-526-3
    • N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride
    • Bonjela
    • Ammonyx T
    • Cetalkonium (Chloride)
    • N-Benzyl-N-cetyldimethylammonium chloride
    • MFCD00011625
    • Hexadecyldimethylbenzylammonium chloride
    • n-Hexadecyldimethylbenzylammonium chloride
    • C25H46ClN
    • Benzenemethanaminium, N-hexadecyl-N,N-dimethyl-, chloride
    • DTXSID3041665
    • Ammonium, benzyldimethylhexadecyl-, chloride
    • Benzalkonium chloride C16 (BAC C16)
    • Benzenemethanaminium, N-hexadecyl, N,N-dimethyl-, chloride
    • Benzylhexadecyldimethylammonium (chloride)
    • N-Benzyl-N,N-dimethylhexadecan-1-aminiumchloride
    • RODALON
    • DTXCID1021665
    • Zettyn chloride
    • Sanisol C
    • Cetalconio cloruro [DCIT]
    • CAS-122-18-9
    • Cetalkonii chloridum [INN-Latin]
    • NCGC00167582-01
    • EINECS 204-526-3
    • Cloruro de cetalconio [INN-Spanish]
    • NSC 32942
    • Chlorure de cetalkonium [INN-French]
    • Cetalkonium chloride [USAN:INN:BAN]
    • 16-BAC
    • AI3-03464
    • UNII-85474O1N9D
    • Zettyn (TN)
    • HDBAC
    • Benzenemethaminium, N-hexadecyl-N,N-dimethyl, chloride
    • benzyl-hexadecyl-dimethylazanium;chloride
    • DSSTox_CID_21665
    • DSSTox_RID_82703
    • DSSTox_GSID_48122
    • SCHEMBL59931
    • BAC 16
    • orb1704849
    • CHEMBL1644450
    • CETALKONIUM CHLORIDE [MI]
    • Cetalkonium chloride (USAN/INN)
    • CETALKONIUM CHLORIDE [INN]
    • CETALKONIUM CHLORIDE [USAN]
    • HY-B1597
    • CETALKONIUM CHLORIDE [VANDF]
    • Tox21_112574
    • Tox21_301833
    • Tox21_302079
    • Benzyldimethylhexadecylammonium chloride 100 microg/mL in Acetonitrile
    • CETALKONIUM CHLORIDE [MART.]
    • EBC-26933
    • MSK001657
    • CETALKONIUM CHLORIDE [WHO-DD]
    • AKOS015914910
    • Tox21_112574_1
    • benzyl(hexadecyl)dimethylazanium chloride
    • MSK001657-1000M
    • NCGC00255210-01
    • NCGC00255704-01
    • NCGC00344524-01
    • AS-17528
    • BP-30079
    • DA-51791
    • benzyl-hexadecyl-dimethyl-ammonium;chloride
    • CAS-63449-41-2
    • DB-253938
    • B0237
    • CS-0013522
    • NS00079326
    • Benzenemethanaminium, N,N-dimethyl-, chloride
    • D03448
    • F16465
    • SBI-0653999.0001
    • Benzyldimethylhexadecylammonium chloride (HDBAC)
    • EN300-7401498
    • Q18345315
    • Benzyldimethylhexadecylammonium chloride, cationic detergent
    • Benzenemethanaminium, N-hexadecyl-N,N-dimethyl-, chloride (1:1)
    • Benzyldimethylhexadecylammonium chloride Solution in Methanol, 1000ug/mL
    • 122-18-9

  • Applications

    Benzylhexadecyldimethylammonium chloride (CAS 122-18-9) is a cationic surfactant used as a conditioning agent and surface-active ingredient in cosmetics and personal care products (shampoos, conditioners, body washes), improving cleansing performance and skin/hair feel. It is also employed as an antimicrobial active ingredient in household and industrial cleaning formulations, ranging from general cleaners to surface sanitizers. In the textile sector, the compound functions as a fabric-softening and surface-treatment agent to enhance processing and fiber hand. Additionally, with its cationic surfactant character, it can be used as an additive in coatings and inks formulations to improve wetting and particle dispersion.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 528.06
    methanol 252.17
    isopropanol 641.9
    water 0.21
    ethyl acetate 2833.42
    n-propanol 800.83
    acetone 2198.67
    n-butanol 1110.58
    acetonitrile 481.77
    DMF 1253.5
    toluene 1304.79
    isobutanol 896.37
    1,4-dioxane 2773.7
    methyl acetate 1524.2
    THF 4467.99
    2-butanone 2100.51
    n-pentanol 707.87
    sec-butanol 853.48
    n-hexane 921.83
    ethylene glycol 24.9
    NMP 1914.26
    cyclohexane 3429.87
    DMSO 1320.28
    n-butyl acetate 3091.53
    n-octanol 616.34
    chloroform 5644.85
    n-propyl acetate 2547.09
    acetic acid 565.69
    dichloromethane 5611.9
    cyclohexanone 5005.03
    propylene glycol 77.67
    isopropyl acetate 2539.7
    DMAc 1841.34
    2-ethoxyethanol 837.53
    isopentanol 1244.64
    n-heptane 1490.23
    ethyl formate 1082.1
    1,2-dichloroethane 3996.33
    n-hexanol 875.22
    2-methoxyethanol 850.46
    isobutyl acetate 1930.52
    tetrachloromethane 2104.47
    n-pentyl acetate 2849.22
    transcutol 3068.61
    n-heptanol 721.19
    ethylbenzene 725.97
    MIBK 2094.78
    2-propoxyethanol 1113.87
    tert-butanol 1133.7
    MTBE 2570.06
    2-butoxyethanol 1197.29
    propionic acid 669.27
    o-xylene 967.54
    formic acid 62.72
    diethyl ether 2989.06
    m-xylene 932.49
    p-xylene 1062.02
    chlorobenzene 1587.95
    dimethyl carbonate 610.2
    n-octane 415.11
    formamide 125.36
    cyclopentanone 3684.96
    2-pentanone 2724.12
    anisole 1021.53
    cyclopentyl methyl ether 3836.79
    gamma-butyrolactone 3035.66
    1-methoxy-2-propanol 924.06
    pyridine 1792.15
    3-pentanone 2362.95
    furfural 1546.83
    n-dodecane 133.66
    diethylene glycol 301.87
    diisopropyl ether 1559.68
    tert-amyl alcohol 1214.47
    acetylacetone 2453.19
    n-hexadecane 164.38
    acetophenone 1119.19
    methyl propionate 1736.3
    isopentyl acetate 2853.23
    trichloroethylene 5152.68
    n-nonanol 617.65
    cyclohexanol 2019.38
    benzyl alcohol 560.02
    2-ethylhexanol 1144.7
    isooctanol 849.17
    dipropyl ether 3683.0
    1,2-dichlorobenzene 1520.46
    ethyl lactate 632.4
    propylene carbonate 1984.23
    n-methylformamide 450.97
    2-pentanol 1080.43
    n-pentane 822.28
    1-propoxy-2-propanol 1464.1
    1-methoxy-2-propyl acetate 1957.14
    2-(2-methoxypropoxy) propanol 656.51
    mesitylene 789.22
    ε-caprolactone 3730.48
    p-cymene 789.23
    epichlorohydrin 3375.93
    1,1,1-trichloroethane 4969.42
    2-aminoethanol 109.22
    morpholine-4-carbaldehyde 1839.33
    sulfolane 3200.14
    2,2,4-trimethylpentane 474.04
    2-methyltetrahydrofuran 4006.99
    n-hexyl acetate 2160.61
    isooctane 314.66
    2-(2-butoxyethoxy)ethanol 1069.25
    sec-butyl acetate 2023.01
    tert-butyl acetate 2934.75
    decalin 709.51
    glycerin 109.19
    diglyme 3019.93
    acrylic acid 362.49
    isopropyl myristate 838.17
    n-butyric acid 1918.74
    acetyl acetate 1618.13
    di(2-ethylhexyl) phthalate 403.82
    ethyl propionate 2171.93
    nitromethane 1165.96
    1,2-diethoxyethane 2728.73
    benzonitrile 798.98
    trioctyl phosphate 408.22
    1-bromopropane 3230.06
    gamma-valerolactone 3592.29
    n-decanol 410.05
    triethyl phosphate 1013.35
    4-methyl-2-pentanol 777.32
    propionitrile 768.5
    vinylene carbonate 1453.46
    1,1,2-trichlorotrifluoroethane 1939.61
    DMS 1086.67
    cumene 580.97
    2-octanol 610.95
    2-hexanone 1987.82
    octyl acetate 897.86
    limonene 1634.72
    1,2-dimethoxyethane 2607.08
    ethyl orthosilicate 1163.67
    tributyl phosphate 545.31
    diacetone alcohol 1744.88
    N,N-dimethylaniline 778.3
    acrylonitrile 554.47
    aniline 925.06
    1,3-propanediol 332.64
    bromobenzene 1998.43
    dibromomethane 4082.98
    1,1,2,2-tetrachloroethane 5336.76
    2-methyl-cyclohexyl acetate 1625.39
    tetrabutyl urea 755.52
    diisobutyl methanol 974.08
    2-phenylethanol 570.13
    styrene 794.18
    dioctyl adipate 928.48
    dimethyl sulfate 958.13
    ethyl butyrate 2909.49
    methyl lactate 462.63
    butyl lactate 1228.66
    diethyl carbonate 1389.27
    propanediol butyl ether 549.92
    triethyl orthoformate 2248.11
    p-tert-butyltoluene 740.53
    methyl 4-tert-butylbenzoate 1123.72
    morpholine 2944.05
    tert-butylamine 1000.27
    n-dodecanol 312.37
    dimethoxymethane 1667.83
    ethylene carbonate 1794.36
    cyrene 631.55
    2-ethoxyethyl acetate 2284.9
    2-ethylhexyl acetate 2541.64
    1,2,4-trichlorobenzene 1660.38
    4-methylpyridine 1873.13
    dibutyl ether 2379.43
    2,6-dimethyl-4-heptanol 974.08
    DEF 2742.47
    dimethyl isosorbide 1395.42
    tetrachloroethylene 3759.92
    eugenol 690.43
    triacetin 1604.17
    span 80 704.3
    1,4-butanediol 142.97
    1,1-dichloroethane 3898.95
    2-methyl-1-pentanol 849.8
    methyl formate 446.47
    2-methyl-1-butanol 1120.93
    n-decane 352.33
    butyronitrile 1250.83
    3,7-dimethyl-1-octanol 787.05
    1-chlorooctane 1027.96
    1-chlorotetradecane 314.03
    n-nonane 397.2
    undecane 198.74
    tert-butylcyclohexane 556.75
    cyclooctane 997.16
    cyclopentanol 1367.61
    tetrahydropyran 5444.55
    tert-amyl methyl ether 2114.65
    2,5,8-trioxanonane 1275.61
    1-hexene 1397.38
    2-isopropoxyethanol 886.32
    2,2,2-trifluoroethanol 305.98
    methyl butyrate 2811.98

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction