Benzyl tetrahydropyran

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  • Identifiers

    CAS number
    60466-73-1

    Molecular formula
    C12H16O

    SMILES
    C1CC(COC1)CC2=CC=CC=C2

    Safety labels

  • Odor profile

    Fragrance
    Green 66.38%
    Fruity 65.66%
    Floral 63.71%
    Sweet 49.5%
    Earthy 46.53%
    Rose 45.98%
    Hyacinth 35.0%
    Metallic 34.97%
    Fresh 34.53%
    Woody 33.46%

     

    Flavor
    Sweet 46.83%
    Green 34.92%
    Floral 33.39%
    Earthy 31.03%
    Rose 30.78%
    Spicy 29.02%
    Fruity 27.99%
    Spice 26.48%
    Woody 23.3%
    Balsam 22.86%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.8

    pKa est.
    6.3 (neutral)

    Molecular weight
    176.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    256°C

    Flash point

    • 103.15 ˚C est.

  • Synonyms

    • Benzyl tetrahydropyran
    • 2H-Pyran, tetrahydro-3-(phenylmethyl)-
    • 3-benzyloxane
    • 60466-73-1
    • 3-benzyltetrahydropyran
    • 8H93S91P0S
    • BETEHYDRANE
    • DTXSID80886400
    • RefChem:566858
    • DTXCID001025730
    • BENZYL TETRAHYDROPYRAN [INCI]
    • 458-610-1
    • UNII-8H93S91P0S
    • SCHEMBL2931658
    • SCHEMBL9790220
    • RLYSPFPWKAALMR-UHFFFAOYSA-N
    • (+/-)-3-BENZYLTETRAHYDROPYRAN
    • 3-BENZYLTETRAHYDROPYRAN, (+/-)-
    • Q27270502
    • 60466-73-1

  • Applications

    Benzyl tetrahydropyran (CAS 60466-73-1) is primarily used as an intermediate in the synthesis of fragrance and aroma compounds, enabling the construction of odor-active molecules for perfume and flavor applications. It may also serve as a specialty solvent or reactive intermediate in industrial organic synthesis. In cosmetics and personal care, it can function as a fragrance ingredient or a precursor to fragrance compounds. In household products and cleaners, it is used as a fragrance component to impart odor. In coatings and inks, it may be used as a fragrance additive or solvent component in formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1536.75
    methanol 1170.51
    isopropanol 846.61
    water 0.29
    ethyl acetate 2318.58
    n-propanol 1075.86
    acetone 1171.46
    n-butanol 1025.81
    acetonitrile 1251.47
    DMF 380.4
    toluene 907.2
    isobutanol 586.56
    1,4-dioxane 3058.93
    methyl acetate 1260.85
    THF 1893.67
    2-butanone 1039.48
    n-pentanol 602.28
    sec-butanol 569.17
    n-hexane 124.05
    ethylene glycol 231.91
    NMP 201.31
    cyclohexane 263.97
    DMSO 1114.16
    n-butyl acetate 1062.45
    n-octanol 163.87
    chloroform 3913.89
    n-propyl acetate 817.03
    acetic acid 925.54
    dichloromethane 4057.02
    cyclohexanone 1054.69
    propylene glycol 307.43
    isopropyl acetate 850.28
    DMAc 367.57
    2-ethoxyethanol 999.83
    isopentanol 673.03
    n-heptane 123.44
    ethyl formate 889.39
    1,2-dichloroethane 2607.17
    n-hexanol 676.73
    2-methoxyethanol 1451.26
    isobutyl acetate 446.56
    tetrachloromethane 406.1
    n-pentyl acetate 304.28
    transcutol 4013.5
    n-heptanol 181.0
    ethylbenzene 292.83
    MIBK 487.48
    2-propoxyethanol 1088.96
    tert-butanol 679.29
    MTBE 827.46
    2-butoxyethanol 412.06
    propionic acid 713.32
    o-xylene 339.29
    formic acid 200.51
    diethyl ether 2194.71
    m-xylene 413.09
    p-xylene 277.13
    chlorobenzene 906.32
    dimethyl carbonate 300.45
    n-octane 31.38
    formamide 312.0
    cyclopentanone 808.61
    2-pentanone 1002.71
    anisole 597.6
    cyclopentyl methyl ether 817.51
    gamma-butyrolactone 1031.68
    1-methoxy-2-propanol 896.13
    pyridine 1995.5
    3-pentanone 737.41
    furfural 1018.15
    n-dodecane 23.95
    diethylene glycol 740.41
    diisopropyl ether 357.62
    tert-amyl alcohol 424.69
    acetylacetone 901.88
    n-hexadecane 27.86
    acetophenone 424.2
    methyl propionate 961.75
    isopentyl acetate 718.96
    trichloroethylene 3537.9
    n-nonanol 150.03
    cyclohexanol 607.04
    benzyl alcohol 433.54
    2-ethylhexanol 377.7
    isooctanol 148.77
    dipropyl ether 901.41
    1,2-dichlorobenzene 617.28
    ethyl lactate 230.44
    propylene carbonate 654.39
    n-methylformamide 428.12
    2-pentanol 576.47
    n-pentane 134.2
    1-propoxy-2-propanol 758.63
    1-methoxy-2-propyl acetate 779.41
    2-(2-methoxypropoxy) propanol 376.61
    mesitylene 217.93
    ε-caprolactone 955.76
    p-cymene 169.59
    epichlorohydrin 2067.86
    1,1,1-trichloroethane 1530.81
    2-aminoethanol 494.24
    morpholine-4-carbaldehyde 774.36
    sulfolane 722.94
    2,2,4-trimethylpentane 51.98
    2-methyltetrahydrofuran 1256.51
    n-hexyl acetate 370.07
    isooctane 48.32
    2-(2-butoxyethoxy)ethanol 633.43
    sec-butyl acetate 458.02
    tert-butyl acetate 591.38
    decalin 86.18
    glycerin 343.15
    diglyme 1390.76
    acrylic acid 502.3
    isopropyl myristate 161.37
    n-butyric acid 1270.62
    acetyl acetate 853.93
    di(2-ethylhexyl) phthalate 135.75
    ethyl propionate 655.1
    nitromethane 1251.88
    1,2-diethoxyethane 1543.4
    benzonitrile 585.5
    trioctyl phosphate 89.39
    1-bromopropane 1488.49
    gamma-valerolactone 1160.71
    n-decanol 114.99
    triethyl phosphate 200.47
    4-methyl-2-pentanol 268.01
    propionitrile 1010.5
    vinylene carbonate 654.65
    1,1,2-trichlorotrifluoroethane 964.63
    DMS 359.07
    cumene 162.36
    2-octanol 94.9
    2-hexanone 566.23
    octyl acetate 177.5
    limonene 255.78
    1,2-dimethoxyethane 1454.02
    ethyl orthosilicate 211.11
    tributyl phosphate 137.9
    diacetone alcohol 466.93
    N,N-dimethylaniline 265.99
    acrylonitrile 985.01
    aniline 772.38
    1,3-propanediol 702.1
    bromobenzene 1024.22
    dibromomethane 2745.15
    1,1,2,2-tetrachloroethane 2312.27
    2-methyl-cyclohexyl acetate 322.02
    tetrabutyl urea 157.73
    diisobutyl methanol 219.85
    2-phenylethanol 404.35
    styrene 469.4
    dioctyl adipate 232.08
    dimethyl sulfate 269.83
    ethyl butyrate 758.12
    methyl lactate 271.35
    butyl lactate 206.35
    diethyl carbonate 433.76
    propanediol butyl ether 287.78
    triethyl orthoformate 424.15
    p-tert-butyltoluene 154.82
    methyl 4-tert-butylbenzoate 257.19
    morpholine 2690.27
    tert-butylamine 473.35
    n-dodecanol 92.85
    dimethoxymethane 1002.84
    ethylene carbonate 650.62
    cyrene 241.08
    2-ethoxyethyl acetate 618.2
    2-ethylhexyl acetate 518.07
    1,2,4-trichlorobenzene 654.95
    4-methylpyridine 1214.51
    dibutyl ether 486.65
    2,6-dimethyl-4-heptanol 219.85
    DEF 784.59
    dimethyl isosorbide 516.23
    tetrachloroethylene 1580.09
    eugenol 253.65
    triacetin 394.66
    span 80 283.78
    1,4-butanediol 247.95
    1,1-dichloroethane 2011.83
    2-methyl-1-pentanol 443.25
    methyl formate 375.47
    2-methyl-1-butanol 561.24
    n-decane 41.16
    butyronitrile 1171.09
    3,7-dimethyl-1-octanol 201.42
    1-chlorooctane 163.76
    1-chlorotetradecane 67.53
    n-nonane 40.99
    undecane 30.37
    tert-butylcyclohexane 71.82
    cyclooctane 92.94
    cyclopentanol 410.46
    tetrahydropyran 2295.4
    tert-amyl methyl ether 473.72
    2,5,8-trioxanonane 747.15
    1-hexene 523.72
    2-isopropoxyethanol 580.74
    2,2,2-trifluoroethanol 211.03
    methyl butyrate 822.73

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction