Benzamide

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  • Identifiers

    CAS number
    55-21-0

    Molecular formula
    C7H7NO

    SMILES
    C1=CC=C(C=C1)C(=O)N

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 35.84%
    Balsamic 32.77%
    Bitter 31.8%
    Honey 28.17%
    Sweet 27.95%
    Burnt 27.29%
    Spicy 24.39%
    Phenolic 24.14%
    Almond 23.85%
    Grape 23.2%

     

    Flavor
    Balsam 36.82%
    Phenolic 34.16%
    Nutty 32.87%
    Odorless 32.29%
    Honey 32.23%
    Faint 32.15%
    Mild 32.15%
    Sour 26.74%
    Sweet 26.5%
    Urine 26.35%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    5.78 (weak acid)

    Molecular weight
    121.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 270 to 271 °F (NTP, 1992)
    • 130 °C
    • 129.1 °C

    Boiling point

    • 554 °F at 760 mmHg (NTP, 1992)
    • 288 °C
    • 290.00 °C. @ 760.00 mm Hg

    Flash point

    • 118.94 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 72.5 °F (NTP, 1992)
    • > 10% in benzene
    • 1 g in 6 ml ethanol; 1 g in 3.3 ml pyridine
    • Soluble in ammonia
    • Slightyl soluble in ethyl ether, benzene; very soluble in ethyl alcohol, carbon tetrachloride, carbon disulfide.
    • In water, 1.35X10+4 mg/l @ 25 °C
    • 13500 mg/L at 25 °C
    • >18.2 [ug/mL] (The mean of the results at pH 7.4)

  • Synonyms

    • Benzamide
    • 55-21-0
    • Benzoylamide
    • Benzoic acid amide
    • Benzenecarboxamide
    • Phenylcarboxyamide
    • Phenylcarboxamide
    • Amid kyseliny benzoove
    • DTXSID0021709
    • AI3-01031
    • NSC-3114
    • DTXCID101709
    • CHEBI:28179
    • 6X80438640
    • RefChem:5585
    • 200-227-7
    • MFCD00007968
    • Amid kyseliny benzoove [Czech]
    • NSC 3114
    • Phenyl Carboxyamide
    • BENZOIC ACID,AMIDE
    • CHEMBL267373
    • benzoylamine
    • CCRIS 4594
    • HSDB 6360
    • EINECS 200-227-7
    • benzeneamide
    • benzimide
    • BRN 0385876
    • phenylamide
    • N-benzoylamine
    • benzoyl nitrogen
    • benzene carboxamide
    • benzene-carboxamide
    • benzene, carbamoyl-
    • Benzamide, 99%
    • UNII-6X80438640
    • BENZAMIDE [MI]
    • BENZAMIDE [HSDB]
    • WLN: ZVR
    • benzene carboximidoic acid
    • PhC(O)NH2
    • Lopac-B-2009
    • bmse000668
    • PhC(=O)NH2
    • SCHEMBL1395
    • Lopac0_000160
    • SCHEMBL16352
    • SCHEMBL55042
    • SCHEMBL55043
    • SCHEMBL96050
    • 4-09-00-00725 (Beilstein Handbook Reference)
    • benzamide (ACD/Name 4.0)
    • MLS000069472
    • SCHEMBL346074
    • SCHEMBL392104
    • Benzamide, p.a., 98.0%
    • orb1300473
    • orb3025880
    • SCHEMBL4627029
    • SCHEMBL7318137
    • SCHEMBL8804677
    • SCHEMBL11496511
    • SCHEMBL30081945
    • NSC3114
    • HMS2231M11
    • HMS3260O22
    • HMS3371I16
    • HMS3885L18
    • CS-Z0019
    • HY-Z0283
    • KZB48947
    • Tox21_200621
    • Tox21_500160
    • BDBM50106187
    • EBC-03174
    • MSK157076
    • s4715
    • SBB058198
    • STK069333
    • AKOS000118773
    • CCG-204255
    • LP00160
    • SDCCGSBI-0050148.P002
    • CAS-55-21-0
    • Benzamide, purum, >=98.0% (HPLC)
    • NCGC00015142-01
    • NCGC00015142-02
    • NCGC00015142-03
    • NCGC00015142-04
    • NCGC00015142-05
    • NCGC00015142-06
    • NCGC00015142-07
    • NCGC00091355-01
    • NCGC00091355-02
    • NCGC00091355-03
    • NCGC00258175-01
    • NCGC00260845-01
    • BP-21224
    • DA-61573
    • DS-17194
    • SMR000059089
    • SY047098
    • Benzamide(Discontinued,See C4X-127042)
    • Benzamide, Vetec(TM) reagent grade, 98%
    • B0012
    • B0220
    • B1418
    • EU-0100160
    • NS00009285
    • ST45040306
    • EN300-15618
    • B 2009
    • Benzamide, purified by sublimation, >=99.5%
    • C09815
    • D70176
    • R00184
    • Q417731
    • SR-01000075601
    • SR-01000075601-1
    • Z33546506
    • Benzamide, zone-refined, purified by sublimation, 99.9%
    • F3145-2903
    • InChI=1/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9
    • Sulfabenzamide|Sulfabenzid|Sulfabenzide|Sulfabenzoylamide|N-Sulfamylbenzamide
    • 55738-52-8
    • 55-21-0

  • Applications

    Benzamide is primarily used as an organic synthesis intermediate, serving as a building block for the preparation of substituted benzamide derivatives in pharmaceutical and agrochemical development. It is also employed as a precursor in the manufacture of dyes and pigments, and as a starting material for certain specialty polymers and resin systems in materials science. In coatings and inks, benzamide-related intermediates can be used to access resin components or coupling agents. It may also be encountered in laboratory research as a reagent for various organic syntheses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 149.87
    methanol 300.43
    isopropanol 84.23
    water 12.33
    ethyl acetate 46.2
    n-propanol 91.69
    acetone 160.56
    n-butanol 68.33
    acetonitrile 67.27
    DMF 602.67
    toluene 20.58
    isobutanol 54.56
    1,4-dioxane 332.48
    methyl acetate 68.25
    THF 249.84
    2-butanone 95.62
    n-pentanol 60.37
    sec-butanol 58.7
    n-hexane 4.59
    ethylene glycol 84.17
    NMP 364.17
    cyclohexane 1.61
    DMSO 519.89
    n-butyl acetate 30.94
    n-octanol 44.96
    chloroform 88.37
    n-propyl acetate 46.94
    acetic acid 121.61
    dichloromethane 55.19
    cyclohexanone 120.49
    propylene glycol 62.68
    isopropyl acetate 38.32
    DMAc 341.92
    2-ethoxyethanol 124.92
    isopentanol 47.63
    n-heptane 4.09
    ethyl formate 53.6
    1,2-dichloroethane 47.43
    n-hexanol 58.09
    2-methoxyethanol 203.84
    isobutyl acetate 35.27
    tetrachloromethane 14.98
    n-pentyl acetate 36.32
    transcutol 211.37
    n-heptanol 46.49
    ethylbenzene 15.91
    MIBK 56.13
    2-propoxyethanol 117.57
    tert-butanol 74.82
    MTBE 53.42
    2-butoxyethanol 88.53
    propionic acid 97.51
    o-xylene 19.92
    formic acid 106.16
    diethyl ether 54.85
    m-xylene 21.5
    p-xylene 21.47
    chlorobenzene 30.8
    dimethyl carbonate 57.34
    n-octane 2.92
    formamide 159.89
    cyclopentanone 216.24
    2-pentanone 73.74
    anisole 54.68
    cyclopentyl methyl ether 81.37
    gamma-butyrolactone 238.22
    1-methoxy-2-propanol 142.38
    pyridine 100.18
    3-pentanone 51.98
    furfural 163.73
    n-dodecane 3.0
    diethylene glycol 123.89
    diisopropyl ether 17.37
    tert-amyl alcohol 57.99
    acetylacetone 91.72
    n-hexadecane 3.31
    acetophenone 51.54
    methyl propionate 65.6
    isopentyl acetate 31.54
    trichloroethylene 91.81
    n-nonanol 39.2
    cyclohexanol 42.69
    benzyl alcohol 46.66
    2-ethylhexanol 31.07
    isooctanol 35.99
    dipropyl ether 31.93
    1,2-dichlorobenzene 29.71
    ethyl lactate 41.29
    propylene carbonate 95.22
    n-methylformamide 226.8
    2-pentanol 42.43
    n-pentane 2.87
    1-propoxy-2-propanol 68.99
    1-methoxy-2-propyl acetate 53.35
    2-(2-methoxypropoxy) propanol 62.45
    mesitylene 14.24
    ε-caprolactone 90.73
    p-cymene 12.47
    epichlorohydrin 160.23
    1,1,1-trichloroethane 39.81
    2-aminoethanol 114.76
    morpholine-4-carbaldehyde 288.39
    sulfolane 296.93
    2,2,4-trimethylpentane 3.17
    2-methyltetrahydrofuran 116.54
    n-hexyl acetate 51.6
    isooctane 3.12
    2-(2-butoxyethoxy)ethanol 97.51
    sec-butyl acetate 30.99
    tert-butyl acetate 46.92
    decalin 3.46
    glycerin 110.67
    diglyme 168.54
    acrylic acid 100.72
    isopropyl myristate 23.48
    n-butyric acid 77.58
    acetyl acetate 35.25
    di(2-ethylhexyl) phthalate 24.82
    ethyl propionate 41.47
    nitromethane 218.14
    1,2-diethoxyethane 52.56
    benzonitrile 47.64
    trioctyl phosphate 22.93
    1-bromopropane 26.19
    gamma-valerolactone 240.24
    n-decanol 30.07
    triethyl phosphate 22.67
    4-methyl-2-pentanol 30.06
    propionitrile 57.87
    vinylene carbonate 84.65
    1,1,2-trichlorotrifluoroethane 124.88
    DMS 46.66
    cumene 14.4
    2-octanol 31.14
    2-hexanone 63.44
    octyl acetate 32.42
    limonene 16.64
    1,2-dimethoxyethane 177.62
    ethyl orthosilicate 21.53
    tributyl phosphate 22.42
    diacetone alcohol 75.83
    N,N-dimethylaniline 43.12
    acrylonitrile 86.52
    aniline 46.62
    1,3-propanediol 116.51
    bromobenzene 22.87
    dibromomethane 34.87
    1,1,2,2-tetrachloroethane 86.58
    2-methyl-cyclohexyl acetate 30.51
    tetrabutyl urea 33.05
    diisobutyl methanol 21.09
    2-phenylethanol 46.13
    styrene 18.35
    dioctyl adipate 30.27
    dimethyl sulfate 115.2
    ethyl butyrate 29.56
    methyl lactate 71.3
    butyl lactate 38.99
    diethyl carbonate 22.88
    propanediol butyl ether 77.69
    triethyl orthoformate 25.26
    p-tert-butyltoluene 13.0
    methyl 4-tert-butylbenzoate 56.55
    morpholine 256.08
    tert-butylamine 40.35
    n-dodecanol 22.59
    dimethoxymethane 189.01
    ethylene carbonate 65.04
    cyrene 68.42
    2-ethoxyethyl acetate 50.4
    2-ethylhexyl acetate 24.36
    1,2,4-trichlorobenzene 39.53
    4-methylpyridine 93.99
    dibutyl ether 30.14
    2,6-dimethyl-4-heptanol 21.09
    DEF 102.88
    dimethyl isosorbide 88.59
    tetrachloroethylene 57.8
    eugenol 62.51
    triacetin 51.62
    span 80 55.27
    1,4-butanediol 60.62
    1,1-dichloroethane 48.14
    2-methyl-1-pentanol 43.27
    methyl formate 148.08
    2-methyl-1-butanol 44.43
    n-decane 4.8
    butyronitrile 50.58
    3,7-dimethyl-1-octanol 31.71
    1-chlorooctane 20.33
    1-chlorotetradecane 8.71
    n-nonane 4.32
    undecane 3.72
    tert-butylcyclohexane 4.6
    cyclooctane 1.13
    cyclopentanol 69.55
    tetrahydropyran 116.2
    tert-amyl methyl ether 39.33
    2,5,8-trioxanonane 114.25
    1-hexene 21.18
    2-isopropoxyethanol 82.95
    2,2,2-trifluoroethanol 62.82
    methyl butyrate 58.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction