Azobisisobutyronitrile

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  • Identifiers

    CAS number
    78-67-1

    Molecular formula
    C8H12N4

    SMILES
    CC(C)(C#N)N=NC(C)(C)C#N

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Woody 36.45%
    Sweet 34.68%
    Citrus 32.14%
    Floral 29.45%
    Mint 26.69%
    Green 25.9%
    Herbal 25.59%
    Spicy 24.4%
    Earthy 24.23%
    Fresh 23.45%

     

    Flavor
    Bitter 44.93%
    Bland 21.23%
    Odorless 21.0%
    Nitrile 17.87%
    Taco 17.48%
    Oriental 17.11%
    Roasted peanuts 17.11%
    Cedarleaf 16.97%
    Scallion 16.81%
    Very strong 16.73%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.3

    pKa est.
    6.49 (neutral)

    Molecular weight
    164.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    201°C

    Melting point expt.

    • 221 °F (105 °C)

    Flash point

    • 109.57 ˚C est.

    Solubility expt.

    • SOL IN METHANOL @ 0, 20, 40 °C: 1.8, 4.96, 16.06 G/100 ML; SOL IN ETHANOL @ 0, 20, 40 °C: 0.58, 2.04, 7.15 G/100 ML
    • INSOL IN WATER; SOL IN MANY ORG SOLVENTS; SOL IN VINYL MONOMERS
    • Solubility in water at 20 °C: none

  • Synonyms

    • 78-67-1
    • 2,2'-Azobis(2-methylpropionitrile)
    • Azobisisobutyronitrile
    • Azdh
    • Porofor N
    • Aceto AZIB
    • Pianofor an
    • Porofor 57
    • Azobis(isobutyronitrile)
    • Chkhz 57
    • VAZO 64
    • AZODIISOBUTYRONITRILE
    • 2,2'-Azobis(2-methylpropanenitrile)
    • 2,2'-azobis(2-cyanopropane)
    • DTXSID1026457
    • PERKADOX AIBN
    • DTXCID60809637
    • alpha,alpha'-azobis(isobutyronitrile)
    • Azobis[isobutyronitrile]
    • 2,2'-Azobis[2-methylpropionitrile]
    • RefChem:560594
    • AIBN
    • 2,2'-Azobisisobutyronitrile
    • Genitron
    • 2,2'-AZOBIS(ISOBUTYRONITRILE)
    • Aivn
    • Vazo
    • Azobisisobutylonitrile
    • 2,2'-Azodiisobutyronitrile
    • Porophor N
    • 34241-39-9
    • (E)-Azobis(isobutyronitrile)
    • 2,2-Azodiisobutyronitrile
    • 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile
    • Propanenitrile, 2,2'-azobis[2-methyl-
    • Azodiisobutyrodinitrile
    • azo-bisisobutyronitrile
    • alpha,alpha'-Azodiisobutyronitrile
    • 2,2'-Dicyano-2,2'-azopropane
    • 2,2'-Dimethyl-2,2'-azodipropiononitrile
    • 2,2-Azobis(2-Methylpropionitrile)
    • NSC 1496
    • Propionitrile, 2,2'-azobis(2-methyl-
    • 2,2'-Azobis[isobutyronitrile]
    • 2,2'-Dimethyl-2,2'-azodipropionitrile
    • Propanenitrile, 2,2'-azobis(2-methyl-
    • Azodi(isobutyronitrile)
    • FZ6PX8U5YB
    • 2,2'-Azobis (2-methylpropionitrile)
    • 2-[(E)-2-(1-cyano-1-methylethyl)diazen-1-yl]-2-methylpropanenitrile
    • Azobis(2-methylpropionitrile)
    • alpha,alpha-azoisobutyronitrile
    • 2,2'-Azodi(isobutyronitrile)
    • (E)-2,2'-(diazene-1,2-diyl)bis(2-methylpropanenitrile)
    • alpha,alpha-Azobisisobutyronitrile
    • NSC-1496
    • NSC-68042
    • 2,2'-Azobis-(2-methylpropanenitrile)
    • Propionitrile, 2,2'-azobis[2-methyl-
    • .alpha.,.alpha.'-Azodi(isobutyronitrile)
    • .alpha.,.alpha.'-Azobis(isobutylonitrile)
    • 2,2'-azodipropionitrile
    • 2,2'-Azobis(2-methylpropionitrile), 98%
    • Propanenitrile, 2,2'-(1,2-diazenediyl)bis(2-methyl-
    • 2,2'-(E)-diazene-1,2-diylbis(2-methylpropanenitrile)
    • 2-(1-cyano-1-methyl-ethyl)azo-2-methyl-propanenitrile
    • Propionitrile,2'-azobis[2-methyl-
    • Propanenitrile,2'-azobis[2-methyl-
    • WLN: NCX1&1&NUNX1&1&CN
    • 2,2'-azobis-(2-methylpropionitrile)
    • 2,2'-azobis-[2-methylpropionitrile]
    • CAS-78-67-1
    • .alpha.,.alpha.'-Azobis(isobutyronitrile)
    • .alpha.,.alpha.'-Azobis[isobutyronitrile]
    • CCRIS 4287
    • HSDB 5220
    • Vazo-64
    • .alpha.,.alpha.'-Azodisobutyric acid dinitrile)
    • azo-bis-isobutyronitrile
    • EINECS 201-132-3
    • UNII-FZ6PX8U5YB
    • AI3-28716
    • alpha,alpha'-Azodiisobutyric acid dinitrile
    • Genitron AZDN
    • Genitron AZDN-FF
    • ADZN
    • azo-diisobutyronitrile
    • azo bisisobutyronitrile
    • azobis isobutyronitrile
    • azobis-isobutylonitrile
    • azobis-isobutyronitrile
    • azobisiso butyronitrile
    • azobisiso-butylonitrile
    • azobisiso-butyronitrile
    • azobisisobutyro nitrile
    • azobisisobutyro-nitrile
    • PEROXAN AZDN
    • azo-di-isobutyronitrile
    • azo(bisisobutyronitrile)
    • azo-bisiso-butyronitrile
    • azobis-iso-butylonitrile
    • azobis-iso-butyronitrile
    • V-60
    • a,a'-azoisobutyronitrile
    • azo-bis-iso-butyronitrile
    • azo-bis-isobutyro-nitrile
    • azobis(iso-butyronitrile)
    • 2-[2-(1-cyano-1-methylethyl)diazen-1-yl]-2-methylpropanenitrile
    • Azobis (isobutyronitrile)
    • POROFOR-57
    • SCHEMBL120
    • SCHEMBL122
    • VAZO CATALYST 64
    • 2,2'azobisisobutyronitrile
    • azo-bis-(isobutyronitrile)
    • 2,2'-azobisisobutyronitril
    • EC 201-132-3
    • trans-Azo-2-cyanoisopropane
    • 2.2'-Azobisisobutyronitrile
    • 2,2'-azodi-isobutyronitrile
    • 2,2-azodi(isobutyronitrile)
    • 2,2'-azo bisisobutyronitrile
    • 2,2'-azobis isobutyronitrile
    • 2,2'-azobis(2cyanopropane)
    • 2,2'-azobis-isobutyronitrile
    • 2,2'-azobisiso-butyronitrile
    • 2,2'-azobisisobutyro-nitrile
    • 78-67-1

  • Applications

    Azobisisobutyronitrile (CAS 78-67-1) is a thermally sensitive free-radical initiator that decomposes to generate radicals at moderate temperatures, enabling controlled free-radical polymerization. In industry, typical applications include: (1) initiation of polymerization for polymers and plastics such as PMMA, polystyrene, and polyacrylates or other vinyl polymers; (2) production of coatings and inks where it starts polymerization and curing during thermal processing; (3) thermally curable adhesives, providing a polymer network through radical initiation; (4) rubber and elastomer synthesis, where it initiates polymerization of specific monomers to form crosslinked networks; (5) laboratory and process chemistry as a general radical initiator for organic syntheses and model polymerizations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 25.2
    methanol 52.21
    isopropanol 29.76
    water 2.6
    ethyl acetate 150.63
    n-propanol 28.44
    acetone 273.97
    n-butanol 25.73
    acetonitrile 147.8
    DMF 595.52
    toluene 117.54
    isobutanol 30.84
    1,4-dioxane 199.04
    methyl acetate 241.92
    THF 302.06
    2-butanone 214.66
    n-pentanol 28.91
    sec-butanol 34.48
    n-hexane 21.82
    ethylene glycol 28.15
    NMP 792.23
    cyclohexane 36.12
    DMSO 395.7
    n-butyl acetate 150.99
    n-octanol 59.61
    chloroform 615.04
    n-propyl acetate 147.85
    acetic acid 112.49
    dichloromethane 512.65
    cyclohexanone 355.67
    propylene glycol 30.85
    isopropyl acetate 125.14
    DMAc 681.8
    2-ethoxyethanol 72.62
    isopentanol 32.19
    n-heptane 20.73
    ethyl formate 143.29
    1,2-dichloroethane 286.53
    n-hexanol 47.89
    2-methoxyethanol 101.39
    isobutyl acetate 115.78
    tetrachloromethane 113.13
    n-pentyl acetate 111.79
    transcutol 219.85
    n-heptanol 38.71
    ethylbenzene 96.42
    MIBK 112.2
    2-propoxyethanol 104.28
    tert-butanol 57.65
    MTBE 91.37
    2-butoxyethanol 78.57
    propionic acid 104.09
    o-xylene 122.23
    formic acid 62.51
    diethyl ether 58.62
    m-xylene 97.76
    p-xylene 174.83
    chlorobenzene 229.23
    dimethyl carbonate 171.94
    n-octane 14.5
    formamide 93.58
    cyclopentanone 516.3
    2-pentanone 132.69
    anisole 201.36
    cyclopentyl methyl ether 150.49
    gamma-butyrolactone 622.57
    1-methoxy-2-propanol 86.76
    pyridine 226.68
    3-pentanone 164.15
    furfural 663.62
    n-dodecane 16.49
    diethylene glycol 89.71
    diisopropyl ether 41.86
    tert-amyl alcohol 59.74
    acetylacetone 342.31
    n-hexadecane 18.73
    acetophenone 293.67
    methyl propionate 176.29
    isopentyl acetate 151.0
    trichloroethylene 719.28
    n-nonanol 54.95
    cyclohexanol 64.31
    benzyl alcohol 110.08
    2-ethylhexanol 54.01
    isooctanol 38.3
    dipropyl ether 73.32
    1,2-dichlorobenzene 305.08
    ethyl lactate 110.27
    propylene carbonate 449.5
    n-methylformamide 193.05
    2-pentanol 25.4
    n-pentane 11.91
    1-propoxy-2-propanol 91.2
    1-methoxy-2-propyl acetate 195.41
    2-(2-methoxypropoxy) propanol 154.74
    mesitylene 79.16
    ε-caprolactone 312.71
    p-cymene 80.59
    epichlorohydrin 408.36
    1,1,1-trichloroethane 412.3
    2-aminoethanol 30.94
    morpholine-4-carbaldehyde 525.73
    sulfolane 881.42
    2,2,4-trimethylpentane 16.4
    2-methyltetrahydrofuran 186.45
    n-hexyl acetate 170.87
    isooctane 10.96
    2-(2-butoxyethoxy)ethanol 129.47
    sec-butyl acetate 110.13
    tert-butyl acetate 168.16
    decalin 34.61
    glycerin 58.93
    diglyme 298.29
    acrylic acid 143.0
    isopropyl myristate 95.69
    n-butyric acid 96.13
    acetyl acetate 232.24
    di(2-ethylhexyl) phthalate 104.2
    ethyl propionate 149.41
    nitromethane 442.91
    1,2-diethoxyethane 114.01
    benzonitrile 221.51
    trioctyl phosphate 73.56
    1-bromopropane 114.92
    gamma-valerolactone 563.92
    n-decanol 44.96
    triethyl phosphate 132.98
    4-methyl-2-pentanol 27.33
    propionitrile 101.53
    vinylene carbonate 439.12
    1,1,2-trichlorotrifluoroethane 391.7
    DMS 288.97
    cumene 81.19
    2-octanol 36.9
    2-hexanone 143.02
    octyl acetate 113.25
    limonene 97.03
    1,2-dimethoxyethane 217.36
    ethyl orthosilicate 104.41
    tributyl phosphate 99.29
    diacetone alcohol 139.04
    N,N-dimethylaniline 189.62
    acrylonitrile 175.66
    aniline 99.68
    1,3-propanediol 33.5
    bromobenzene 274.49
    dibromomethane 295.46
    1,1,2,2-tetrachloroethane 618.66
    2-methyl-cyclohexyl acetate 169.85
    tetrabutyl urea 139.24
    diisobutyl methanol 44.54
    2-phenylethanol 114.82
    styrene 118.99
    dioctyl adipate 160.88
    dimethyl sulfate 429.17
    ethyl butyrate 147.71
    methyl lactate 140.05
    butyl lactate 101.09
    diethyl carbonate 141.38
    propanediol butyl ether 96.77
    triethyl orthoformate 115.86
    p-tert-butyltoluene 80.47
    methyl 4-tert-butylbenzoate 224.3
    morpholine 155.45
    tert-butylamine 41.93
    n-dodecanol 39.93
    dimethoxymethane 184.93
    ethylene carbonate 300.4
    cyrene 227.03
    2-ethoxyethyl acetate 152.25
    2-ethylhexyl acetate 134.34
    1,2,4-trichlorobenzene 394.02
    4-methylpyridine 275.78
    dibutyl ether 87.44
    2,6-dimethyl-4-heptanol 44.54
    DEF 226.77
    dimethyl isosorbide 329.62
    tetrachloroethylene 377.43
    eugenol 182.3
    triacetin 307.05
    span 80 129.31
    1,4-butanediol 26.29
    1,1-dichloroethane 267.57
    2-methyl-1-pentanol 35.36
    methyl formate 240.06
    2-methyl-1-butanol 32.08
    n-decane 22.78
    butyronitrile 78.66
    3,7-dimethyl-1-octanol 66.63
    1-chlorooctane 77.27
    1-chlorotetradecane 41.33
    n-nonane 21.9
    undecane 18.81
    tert-butylcyclohexane 32.94
    cyclooctane 18.29
    cyclopentanol 82.33
    tetrahydropyran 127.95
    tert-amyl methyl ether 89.8
    2,5,8-trioxanonane 241.94
    1-hexene 45.23
    2-isopropoxyethanol 63.9
    2,2,2-trifluoroethanol 114.57
    methyl butyrate 200.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction