Avenacoside A

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  • Identifiers

    CAS number
    24915-65-9

    Molecular formula
    C51H82O23

    SMILES
    C[C@H]1[C@H]2[C@H](C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)C)C)O[C@]19CC[C@@](O9)(C)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 63.27%
    Sweet 32.3%
    Woody 26.19%
    Cooling 21.83%
    Spicy 19.45%
    Vanilla 18.4%
    Milky 18.15%
    Mint 17.97%
    Warm 17.0%
    Clean 16.42%

     

    Flavor
    Bitter 46.09%
    Sweet 43.69%
    Fatty 41.17%
    Odorless 34.66%
    Sweet-like 29.07%
    Metallic 22.92%
    Cauliflower 22.14%
    Bland 21.56%
    Alkaline 21.4%
    Mentholic 21.0%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.0

    pKa est.
    4.33 (weak acid)

    Molecular weight
    1063.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    3344°C

    Flash point

    • 205.54 ˚C est.

  • Synonyms

    • CHEBI:2937
    • nuatigenin 3-O-{alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-beta-D-glucopyranoside}-26-O-beta-D-glucopyranoside
    • (3beta,22S,25S)-3-{[6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-beta-D-glucopyranosyl]oxy}-22,25-epoxyfurost-5-en-26-yl beta-D-glucopyranoside
    • (3beta,22S,25S)-3-((6-deoxy-alpha-L-mannopyranosyl-(1->2)-(beta-D-glucopyranosyl-(1->4))-beta-D-glucopyranosyl)oxy)-22,25-epoxyfurost-5-en-26-yl beta-D-glucopyranoside
    • Nuatigenin 3-O-(alpha-L-rhamnopyranosyl-(1->2)-(beta-D-glucopyranosyl-(1->4))-beta-D-glucopyranoside)-26-O-beta-D-glucopyranoside
    • RefChem:115746
    • nuatigenin 3-O-(alpha-L-rhamnopyranosyl-(1-2)-(beta-D-glucopyranosyl-(1-4))-beta-D-glucopyranoside)-26-O-beta-D-glucopyranoside
    • (2S,3R,4R,5R,6S)-2-((2R,3R,4S,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-((1S,2S,4S,5'S,6S,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethyl-5'-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxymethyl)spiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icos-18-ene-6,2'-oxolane)-16-yl)oxy-5-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxan-3-yl)oxy-6-methyloxane-3,4,5-triol
    • 24915-65-9
    • Avenacoside A
    • SCHEMBL30834767
    • C08887
    • Q27105892
    • 3-O-{alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-beta-D-glucopyranoside}-26-O-beta-D-glucopyranoside
    • 24915-65-9

  • Applications

    Avenacoside A (CAS 24915-65-9) is a natural steroidal saponin derived from oats. In industrial and consumer formulations it is commonly evaluated as a natural surfactant and foaming agent, functioning as an emulsifier and wetting agent in cosmetics and personal care products as well as in cleaning and household formulations. It can also serve as an intermediate or building block for glycoside derivatives in research and development. Additionally, owing to its surface-active properties and potential bioactivity, it is explored for applications in coatings/inks and other formulation contexts, with handling and use governed by local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.73
    methanol 23.89
    isopropanol 0.49
    water 0.29
    ethyl acetate 2.38
    n-propanol 1.05
    acetone 4.34
    n-butanol 0.49
    acetonitrile 2.16
    DMF 52.25
    toluene 0.47
    isobutanol 0.4
    1,4-dioxane 8.74
    methyl acetate 3.03
    THF 12.98
    2-butanone 2.31
    n-pentanol 0.46
    sec-butanol 0.34
    n-hexane 0.01
    ethylene glycol 5.8
    NMP 49.81
    cyclohexane 0.03
    DMSO 61.33
    n-butyl acetate 1.07
    n-octanol 0.93
    chloroform 4.36
    n-propyl acetate 1.22
    acetic acid 37.23
    dichloromethane 5.05
    cyclohexanone 3.69
    propylene glycol 3.32
    isopropyl acetate 1.32
    DMAc 39.44
    2-ethoxyethanol 9.54
    isopentanol 0.3
    n-heptane 0.04
    ethyl formate 3.48
    1,2-dichloroethane 1.83
    n-hexanol 0.43
    2-methoxyethanol 23.08
    isobutyl acetate 0.64
    tetrachloromethane 0.46
    n-pentyl acetate 2.58
    transcutol 21.15
    n-heptanol 1.02
    ethylbenzene 0.2
    MIBK 0.94
    2-propoxyethanol 9.26
    tert-butanol 0.35
    MTBE 0.39
    2-butoxyethanol 8.73
    propionic acid 3.79
    o-xylene 0.35
    formic acid 72.81
    diethyl ether 0.74
    m-xylene 0.35
    p-xylene 0.25
    chlorobenzene 0.77
    dimethyl carbonate 8.81
    n-octane 0.02
    formamide 49.65
    cyclopentanone 9.36
    2-pentanone 1.7
    anisole 1.44
    cyclopentyl methyl ether 2.11
    gamma-butyrolactone 18.14
    1-methoxy-2-propanol 9.55
    pyridine 5.65
    3-pentanone 1.52
    furfural 30.32
    n-dodecane 0.02
    diethylene glycol 13.74
    diisopropyl ether 0.15
    tert-amyl alcohol 0.33
    acetylacetone 8.01
    n-hexadecane 0.03
    acetophenone 2.51
    methyl propionate 4.01
    isopentyl acetate 0.88
    trichloroethylene 7.6
    n-nonanol 0.99
    cyclohexanol 0.41
    benzyl alcohol 1.88
    2-ethylhexanol 0.27
    isooctanol 0.63
    dipropyl ether 0.71
    1,2-dichlorobenzene 1.05
    ethyl lactate 2.83
    propylene carbonate 7.12
    n-methylformamide 26.05
    2-pentanol 0.22
    n-pentane 0.02
    1-propoxy-2-propanol 4.58
    1-methoxy-2-propyl acetate 4.74
    2-(2-methoxypropoxy) propanol 6.43
    mesitylene 0.19
    ε-caprolactone 5.17
    p-cymene 0.23
    epichlorohydrin 15.49
    1,1,1-trichloroethane 0.95
    2-aminoethanol 5.6
    morpholine-4-carbaldehyde 55.87
    sulfolane 42.58
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 1.97
    n-hexyl acetate 2.52
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 9.72
    sec-butyl acetate 0.63
    tert-butyl acetate 1.32
    decalin 0.02
    glycerin 16.51
    diglyme 21.77
    acrylic acid 10.82
    isopropyl myristate 0.58
    n-butyric acid 3.27
    acetyl acetate 4.18
    di(2-ethylhexyl) phthalate 1.49
    ethyl propionate 1.32
    nitromethane 69.1
    1,2-diethoxyethane 2.72
    benzonitrile 1.78
    trioctyl phosphate 0.93
    1-bromopropane 0.36
    gamma-valerolactone 41.12
    n-decanol 0.55
    triethyl phosphate 1.05
    4-methyl-2-pentanol 0.17
    propionitrile 1.01
    vinylene carbonate 11.25
    1,1,2-trichlorotrifluoroethane 39.6
    DMS 3.62
    cumene 0.15
    2-octanol 0.49
    2-hexanone 0.97
    octyl acetate 1.21
    limonene 0.27
    1,2-dimethoxyethane 10.64
    ethyl orthosilicate 0.88
    tributyl phosphate 0.79
    diacetone alcohol 3.35
    N,N-dimethylaniline 1.14
    acrylonitrile 3.4
    aniline 1.13
    1,3-propanediol 4.23
    bromobenzene 0.66
    dibromomethane 1.49
    1,1,2,2-tetrachloroethane 4.3
    2-methyl-cyclohexyl acetate 1.06
    tetrabutyl urea 1.48
    diisobutyl methanol 0.17
    2-phenylethanol 1.76
    styrene 0.27
    dioctyl adipate 1.65
    dimethyl sulfate 23.38
    ethyl butyrate 1.11
    methyl lactate 9.97
    butyl lactate 3.88
    diethyl carbonate 0.86
    propanediol butyl ether 8.98
    triethyl orthoformate 1.37
    p-tert-butyltoluene 0.22
    methyl 4-tert-butylbenzoate 5.26
    morpholine 8.9
    tert-butylamine 0.1
    n-dodecanol 0.31
    dimethoxymethane 22.59
    ethylene carbonate 5.72
    cyrene 13.89
    2-ethoxyethyl acetate 8.1
    2-ethylhexyl acetate 0.69
    1,2,4-trichlorobenzene 1.7
    4-methylpyridine 2.91
    dibutyl ether 0.48
    2,6-dimethyl-4-heptanol 0.17
    DEF 5.11
    dimethyl isosorbide 12.62
    tetrachloroethylene 3.49
    eugenol 6.03
    triacetin 8.07
    span 80 6.1
    1,4-butanediol 1.89
    1,1-dichloroethane 0.89
    2-methyl-1-pentanol 0.28
    methyl formate 24.58
    2-methyl-1-butanol 0.31
    n-decane 0.05
    butyronitrile 0.65
    3,7-dimethyl-1-octanol 0.46
    1-chlorooctane 0.25
    1-chlorotetradecane 0.08
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.01
    cyclooctane 0.02
    cyclopentanol 0.87
    tetrahydropyran 1.59
    tert-amyl methyl ether 0.43
    2,5,8-trioxanonane 13.59
    1-hexene 0.06
    2-isopropoxyethanol 3.72
    2,2,2-trifluoroethanol 18.28
    methyl butyrate 1.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction