Aristolactone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    6790-85-8

    Retention indicies (RI)

    • DB5: 2060.0
    • Carbowax: 2633.0

  • Properties

  • Applications

    Aristolactone (CAS 6790-85-8) is primarily of interest in natural product chemistry and alkaloid research, where it serves as a synthetic building block or intermediate for related aristolochic alkaloids, and as a reference compound for analytical method development (HPLC/LC-MS) to detect and quantify aristolochic compounds in samples. It is used in academic toxicology and pharmacology studies to explore structure–activity relationships within this class, and as a research standard for isolation and characterization of aristolochia-derived constituents. Its use in consumer products is limited and subject to local regulations due to toxicity concerns.

    gpt-5-nano

1 2

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Aristolochia gibertii leaf Aristolochia gibertii Hook., fam. Aristolochiaceae 8.8%
Aristolochia gibertii stem Aristolochia gibertii Hook., fam. Aristolochiaceae 3.0%