Anserine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    584-85-0

    Molecular formula
    C10H16N4O3

    SMILES
    CN1C=NC=C1C[C@@H](C(=O)O)NC(=O)CCN

    Safety labels

  • Odor profile

    Fragrance
    Odorless 76.94%
    Savory 40.83%
    Meaty 31.55%
    Cooling 26.02%
    Fishy 23.39%
    Cooked 22.27%
    Roasted 17.81%
    Milky 17.36%
    Popcorn 15.61%
    Cheesy 14.72%

     

    Flavor
    Bitter 63.23%
    Odorless 61.62%
    Bland 33.7%
    Mild 29.13%
    Sweet-like 22.94%
    Very mild 22.83%
    Yeast 20.88%
    Nitrile 19.99%
    Bread crust 19.3%
    Roasted peanuts 19.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -4.0

    pKa est.
    5.87 (weak acid)

    Molecular weight
    240.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    271°C

    Melting point expt.

    • 226 - 228 °C

    Flash point

    • 251.48 ˚C est.

  • Synonyms

    • L-Anserine
    • ANSERINE
    • 584-85-0
    • beta-alanyl-3-methyl-L-histidine
    • HDQ4N37UGV
    • DTXSID30973950
    • (2S)-2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid
    • L-Histidine, N-beta-alanyl-3-methyl-
    • CHEBI:18323
    • (2S)-2-(3-aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
    • Balanine
    • Beta Alanyl 3 Methylhistidine
    • Beta-Alanyl-3-Methylhistidine
    • RefChem:915936
    • DTXCID201401390
    • (2S)-2-(3-azaniumylpropanoylamino)-3-(3-methylimidazol-4-yl)propanoate
    • (2S)-2-((3-Amino-1-Oxopropyl)Amino)-3-(3-Methyl-4-Imidazolyl)Propanoic Acid
    • 209-545-0
    • Ophidine
    • MFCD11040910
    • N-beta-Alanyl-3-methyl-L-histidine
    • beta-Alanyl-N(pai)-methyl-L-histidine
    • Na-(3-aminopropanoyl)-Np-methyl-L-histidine
    • (S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
    • (2~{S})-2-(3-azanylpropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid
    • UNII-HDQ4N37UGV
    • EINECS 209-545-0
    • beta-Alanyl-N(pi)-methyl-L-histidine
    • Anserine [WHO-DD]
    • (2S)-2-[(3-ammoniopropanoyl)amino]-3-(1-methyl-1H-imidazol-5-yl)propanoate
    • ANSERINE [MI]
    • SCHEMBL34255
    • H-beta-Ala-His(3-Me)-OH
    • H-?-Ala-His(3-Me)-OH
    • CHEMBL448301
    • orb1306053
    • L-N-b-alanyl-3-methyl-Histidine
    • N-b-alanyl-3-methyl-L-Histidine
    • L-N-beta-alanyl-3-methyl-Histidine
    • MSK001356
    • s6141
    • AKOS015896389
    • EBC-616073
    • FA34800
    • AS-19301
    • SY105498
    • HY-113354
    • CS-0062279
    • NS00015140
    • L-HISTIDINE, .BETA.-ALANYL-3-METHYL-
    • C01262
    • I11595
    • L-HISTIDINE, N-.BETA.-ALANYL-3-METHYL-
    • N(alpha)-(beta-alanyl)-N(pros)-methylhistidine
    • Q415335
    • HISTIDINE, N-.BETA.-ALANYL-3-METHYL-, L-
    • (S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoicacid
    • 8V3
    • 584-85-0

  • Applications

    Anserine (CAS 584-85-0) is a dipeptide antioxidant used across several industries; in food processing it is evaluated as a natural antioxidant to retard lipid oxidation and preserve quality; in cosmetics and personal care it is investigated as a bioactive peptide antioxidant for skin-care formulations; in nutraceuticals and dietary supplements it is studied for supporting antioxidant status; in animal nutrition and agriculture it can be added to feeds to support endogenous antioxidant defenses; in coatings, inks, and polymer formulations it may act as an antioxidant stabilizer to extend shelf life and durability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.37
    methanol 12.74
    isopropanol 0.99
    water 340.86
    ethyl acetate 0.62
    n-propanol 1.55
    acetone 0.92
    n-butanol 0.99
    acetonitrile 1.29
    DMF 157.69
    toluene 0.4
    isobutanol 1.19
    1,4-dioxane 2.46
    methyl acetate 0.82
    THF 4.7
    2-butanone 1.06
    n-pentanol 0.76
    sec-butanol 1.16
    n-hexane 0.12
    ethylene glycol 24.49
    NMP 227.01
    cyclohexane 0.24
    DMSO 128.38
    n-butyl acetate 0.64
    n-octanol 0.16
    chloroform 1.18
    n-propyl acetate 0.49
    acetic acid 61.23
    dichloromethane 1.82
    cyclohexanone 5.41
    propylene glycol 17.87
    isopropyl acetate 0.45
    DMAc 137.65
    2-ethoxyethanol 9.71
    isopentanol 1.05
    n-heptane 0.09
    ethyl formate 4.29
    1,2-dichloroethane 1.11
    n-hexanol 0.68
    2-methoxyethanol 28.5
    isobutyl acetate 0.29
    tetrachloromethane 0.66
    n-pentyl acetate 0.3
    transcutol 7.09
    n-heptanol 0.36
    ethylbenzene 0.28
    MIBK 0.61
    2-propoxyethanol 5.36
    tert-butanol 1.71
    MTBE 0.39
    2-butoxyethanol 2.46
    propionic acid 8.36
    o-xylene 0.7
    formic acid 509.45
    diethyl ether 0.3
    m-xylene 0.41
    p-xylene 0.56
    chlorobenzene 0.47
    dimethyl carbonate 3.28
    n-octane 0.04
    formamide 302.09
    cyclopentanone 8.9
    2-pentanone 0.68
    anisole 0.63
    cyclopentyl methyl ether 1.88
    gamma-butyrolactone 19.26
    1-methoxy-2-propanol 9.01
    pyridine 3.93
    3-pentanone 0.92
    furfural 44.65
    n-dodecane 0.02
    diethylene glycol 19.73
    diisopropyl ether 0.14
    tert-amyl alcohol 1.86
    acetylacetone 1.91
    n-hexadecane 0.02
    acetophenone 1.75
    methyl propionate 1.62
    isopentyl acetate 0.79
    trichloroethylene 2.71
    n-nonanol 0.19
    cyclohexanol 1.94
    benzyl alcohol 2.31
    2-ethylhexanol 0.43
    isooctanol 0.33
    dipropyl ether 0.39
    1,2-dichlorobenzene 0.71
    ethyl lactate 2.43
    propylene carbonate 10.87
    n-methylformamide 60.81
    2-pentanol 0.53
    n-pentane 0.1
    1-propoxy-2-propanol 2.48
    1-methoxy-2-propyl acetate 2.09
    2-(2-methoxypropoxy) propanol 3.77
    mesitylene 0.35
    ε-caprolactone 6.84
    p-cymene 0.32
    epichlorohydrin 6.82
    1,1,1-trichloroethane 0.7
    2-aminoethanol 23.19
    morpholine-4-carbaldehyde 71.38
    sulfolane 79.05
    2,2,4-trimethylpentane 0.07
    2-methyltetrahydrofuran 2.18
    n-hexyl acetate 0.29
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 3.78
    sec-butyl acetate 0.33
    tert-butyl acetate 0.7
    decalin 0.09
    glycerin 82.83
    diglyme 8.22
    acrylic acid 21.64
    isopropyl myristate 0.13
    n-butyric acid 6.46
    acetyl acetate 1.05
    di(2-ethylhexyl) phthalate 0.82
    ethyl propionate 0.61
    nitromethane 42.65
    1,2-diethoxyethane 0.49
    benzonitrile 1.68
    trioctyl phosphate 0.4
    1-bromopropane 0.36
    gamma-valerolactone 32.46
    n-decanol 0.15
    triethyl phosphate 1.42
    4-methyl-2-pentanol 0.41
    propionitrile 0.98
    vinylene carbonate 10.47
    1,1,2-trichlorotrifluoroethane 43.57
    DMS 1.1
    cumene 0.28
    2-octanol 0.18
    2-hexanone 0.51
    octyl acetate 0.19
    limonene 0.39
    1,2-dimethoxyethane 7.91
    ethyl orthosilicate 1.16
    tributyl phosphate 0.58
    diacetone alcohol 3.72
    N,N-dimethylaniline 1.2
    acrylonitrile 2.85
    aniline 1.73
    1,3-propanediol 13.14
    bromobenzene 0.36
    dibromomethane 0.89
    1,1,2,2-tetrachloroethane 2.44
    2-methyl-cyclohexyl acetate 0.98
    tetrabutyl urea 1.13
    diisobutyl methanol 0.32
    2-phenylethanol 1.37
    styrene 0.29
    dioctyl adipate 0.38
    dimethyl sulfate 19.44
    ethyl butyrate 0.74
    methyl lactate 9.93
    butyl lactate 1.48
    diethyl carbonate 0.84
    propanediol butyl ether 3.47
    triethyl orthoformate 1.08
    p-tert-butyltoluene 0.29
    methyl 4-tert-butylbenzoate 2.1
    morpholine 5.5
    tert-butylamine 0.6
    n-dodecanol 0.12
    dimethoxymethane 6.36
    ethylene carbonate 6.13
    cyrene 16.11
    2-ethoxyethyl acetate 0.69
    2-ethylhexyl acetate 0.61
    1,2,4-trichlorobenzene 1.24
    4-methylpyridine 3.02
    dibutyl ether 0.13
    2,6-dimethyl-4-heptanol 0.32
    DEF 6.87
    dimethyl isosorbide 8.62
    tetrachloroethylene 2.43
    eugenol 3.28
    triacetin 1.25
    span 80 2.55
    1,4-butanediol 6.11
    1,1-dichloroethane 0.5
    2-methyl-1-pentanol 0.92
    methyl formate 31.04
    2-methyl-1-butanol 1.29
    n-decane 0.03
    butyronitrile 0.86
    3,7-dimethyl-1-octanol 0.22
    1-chlorooctane 0.06
    1-chlorotetradecane 0.03
    n-nonane 0.03
    undecane 0.02
    tert-butylcyclohexane 0.05
    cyclooctane 0.09
    cyclopentanol 3.74
    tetrahydropyran 1.21
    tert-amyl methyl ether 0.63
    2,5,8-trioxanonane 6.74
    1-hexene 0.24
    2-isopropoxyethanol 3.05
    2,2,2-trifluoroethanol 53.63
    methyl butyrate 1.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction