Androstenol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1153-51-1

    Molecular formula
    C19H30O

    SMILES
    C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@H]4[C@@]3(CC[C@H](C4)O)C

  • Odor profile

    Fragrance
    Woody 63.66%
    Sweet 53.23%
    Musk 41.84%
    Sandalwood 41.39%
    Amber 41.28%
    Balsamic 38.93%
    Dry 38.33%
    Clean 35.86%
    Floral 32.43%
    Cedar 31.53%

     

    Flavor
    Sweet 38.89%
    Woody 35.19%
    Herb 31.32%
    Earthy 31.18%
    Wood 30.48%
    Dry 27.79%
    Herbal 27.66%
    Camphor 26.44%
    Fir needle 26.15%
    Fruity 25.92%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    7.61 (neutral)

    Molecular weight
    274.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    387°C

    Melting point expt.

    • 142.75 °C

    Flash point

    • 184.26 ˚C est.

  • Synonyms

    • Androstenol
    • 1153-51-1
    • 5alpha-Androst-16-en-3alpha-ol
    • 16,17-ANDROSTENE-3-OL
    • Androst-16-en-3alpha-ol
    • Androst-16-en-3-ol
    • 3alpha-Hydroxyandrost-16-ene
    • (3alpha,5alpha)-Androst-16-en-3-ol
    • 5.alpha.-Androst-16-en-3.alpha.-ol
    • alpha-androstenol
    • Androst-16-en-3-ol, (3alpha,5alpha)-
    • Androst-16-en-3-ol, (3.alpha.,5.alpha.)-
    • CHEBI:40933
    • EINECS 214-573-1
    • NSC 71076
    • NSC-71076
    • (3R,5S,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
    • CHEMBL142348
    • DTXSID2075394
    • 3.alpha.-Hydroxyandrost-16-ene
    • 48K9VAM062
    • 3alpha-Hydroxy-5alpha-androst-16-ene
    • 3.ALPHA.-HYDROXY-5.ALPHA.-ANDROST-16-ENE
    • (3.ALPHA.,5.ALPHA.)-ANDROST-16-EN-3-OL [MI]
    • 3?-Hydroxy-5?-Androst-16-ene
    • (3aS,3bR,5aS,7R,9aS,9bS,11aR)-9a,11a-dimethyl-3H,3aH,3bH,4H,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol
    • UNII-48K9VAM062
    • Androst-16-en-3-ol,5.alpha.)-
    • 5-alpha-Androst-16-en-3-alpha-ol
    • |A-Androstenol
    • 5|A-Androst-16-en-3|A-ol
    • 1xnx
    • (3a,5a)-Androst-16-en-3-ol
    • (3R,5S,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol
    • 3a-Hydroxyandrostene
    • Spectrum5_002029
    • 3a-Hydroxyandrost-16-ene
    • Androst-16-en-3-ol #
    • 5a-androst-16-en-3a-ol
    • SCHEMBL324888
    • 3-Hydroxy-5-Androst-16-ene
    • GTPL2761
    • 3a-Hydroxy-5a-androst-16-ene
    • DTXCID7033365
    • 16-(5alpha)Androsten-3alpha-ol
    • NSC71076
    • BDBM50134722
    • LMST02020008
    • MFCD00051224
    • (3beta,5alpha)-androst-16-en-3-ol
    • AKOS017343734
    • DB01889
    • FA63499
    • 5.alpha.-Androst-16-ene-3.alpha.-ol
    • 5alpha-Androst-16-en-3alpha-ol, >=98%
    • CS-0760932
    • NS00023736
    • Androst-16-en-3-ol, (3alpha,5alpha)-(9CI)
    • Androstenol; (3alpha, 5alpha)-Androst-16-en-3-ol
    • Q2567125
    • BRD-K24994810-001-01-9
    • (3R,5S,8R,9S,10S,13R,14S)-10,13-Dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
    • 214-573-1
    • 234-925-8

  • Applications

    Androstenol (CAS 1153-51-1) is used primarily as a fragrance ingredient and odorant in perfumery and cosmetics, where it contributes a musk/animalic note and can help fix or extend scents; it is regarded as a pheromone-like compound and may be evaluated for personal care formulations and household products to impart a distinctive scent; in industrial manufacturing it serves as an intermediate in steroid synthesis; it may also be used as a scent additive in household products such as detergents and air fresheners, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 610.76
    methanol 317.73
    isopropanol 695.02
    water 1.11
    ethyl acetate 704.83
    n-propanol 667.29
    acetone 954.22
    n-butanol 797.95
    acetonitrile 365.51
    DMF 703.42
    toluene 771.02
    isobutanol 386.11
    1,4-dioxane 1292.38
    methyl acetate 373.35
    THF 2216.57
    2-butanone 613.55
    n-pentanol 116.86
    sec-butanol 178.15
    n-hexane 22.4
    ethylene glycol 23.55
    NMP 84.78
    cyclohexane 127.79
    DMSO 207.3
    n-butyl acetate 336.49
    n-octanol 61.31
    chloroform 867.58
    n-propyl acetate 177.9
    acetic acid 91.9
    dichloromethane 607.04
    cyclohexanone 557.9
    propylene glycol 32.69
    isopropyl acetate 524.14
    DMAc 219.18
    2-ethoxyethanol 197.45
    isopentanol 466.13
    n-heptane 30.32
    ethyl formate 209.86
    1,2-dichloroethane 471.74
    n-hexanol 246.18
    2-methoxyethanol 670.02
    isobutyl acetate 155.57
    tetrachloromethane 153.15
    n-pentyl acetate 157.39
    transcutol 1047.96
    n-heptanol 94.6
    ethylbenzene 136.25
    MIBK 421.34
    2-propoxyethanol 488.43
    tert-butanol 469.39
    MTBE 720.44
    2-butoxyethanol 216.11
    propionic acid 106.44
    o-xylene 232.96
    formic acid 28.45
    diethyl ether 1421.25
    m-xylene 415.91
    p-xylene 142.35
    chlorobenzene 310.05
    dimethyl carbonate 164.11
    n-octane 10.96
    formamide 77.73
    cyclopentanone 637.24
    2-pentanone 791.72
    anisole 234.96
    cyclopentyl methyl ether 654.52
    gamma-butyrolactone 414.23
    1-methoxy-2-propanol 562.92
    pyridine 697.22
    3-pentanone 414.21
    furfural 268.46
    n-dodecane 7.19
    diethylene glycol 229.0
    diisopropyl ether 284.74
    tert-amyl alcohol 118.48
    acetylacetone 530.82
    n-hexadecane 8.81
    acetophenone 139.63
    methyl propionate 407.37
    isopentyl acetate 319.79
    trichloroethylene 585.25
    n-nonanol 63.6
    cyclohexanol 256.37
    benzyl alcohol 127.02
    2-ethylhexanol 112.45
    isooctanol 79.79
    dipropyl ether 324.95
    1,2-dichlorobenzene 198.23
    ethyl lactate 67.55
    propylene carbonate 193.37
    n-methylformamide 264.05
    2-pentanol 288.64
    n-pentane 71.23
    1-propoxy-2-propanol 321.31
    1-methoxy-2-propyl acetate 411.44
    2-(2-methoxypropoxy) propanol 161.3
    mesitylene 219.86
    ε-caprolactone 330.73
    p-cymene 82.41
    epichlorohydrin 622.84
    1,1,1-trichloroethane 379.52
    2-aminoethanol 81.21
    morpholine-4-carbaldehyde 284.88
    sulfolane 191.8
    2,2,4-trimethylpentane 17.87
    2-methyltetrahydrofuran 686.42
    n-hexyl acetate 168.52
    isooctane 29.02
    2-(2-butoxyethoxy)ethanol 279.01
    sec-butyl acetate 155.23
    tert-butyl acetate 408.06
    decalin 24.09
    glycerin 60.8
    diglyme 566.5
    acrylic acid 63.06
    isopropyl myristate 76.32
    n-butyric acid 348.08
    acetyl acetate 262.84
    di(2-ethylhexyl) phthalate 62.94
    ethyl propionate 196.59
    nitromethane 244.14
    1,2-diethoxyethane 505.0
    benzonitrile 200.28
    trioctyl phosphate 50.09
    1-bromopropane 444.41
    gamma-valerolactone 674.33
    n-decanol 48.92
    triethyl phosphate 76.09
    4-methyl-2-pentanol 186.45
    propionitrile 526.78
    vinylene carbonate 212.85
    1,1,2-trichlorotrifluoroethane 161.12
    DMS 145.47
    cumene 77.63
    2-octanol 50.41
    2-hexanone 149.7
    octyl acetate 82.59
    limonene 94.07
    1,2-dimethoxyethane 537.95
    ethyl orthosilicate 86.85
    tributyl phosphate 55.69
    diacetone alcohol 257.2
    N,N-dimethylaniline 115.32
    acrylonitrile 376.92
    aniline 441.29
    1,3-propanediol 321.36
    bromobenzene 353.68
    dibromomethane 465.89
    1,1,2,2-tetrachloroethane 411.64
    2-methyl-cyclohexyl acetate 118.11
    tetrabutyl urea 66.72
    diisobutyl methanol 98.0
    2-phenylethanol 189.33
    styrene 161.55
    dioctyl adipate 85.69
    dimethyl sulfate 121.68
    ethyl butyrate 217.08
    methyl lactate 102.17
    butyl lactate 110.94
    diethyl carbonate 126.18
    propanediol butyl ether 124.61
    triethyl orthoformate 156.59
    p-tert-butyltoluene 88.88
    methyl 4-tert-butylbenzoate 143.2
    morpholine 1238.51
    tert-butylamine 346.0
    n-dodecanol 37.84
    dimethoxymethane 1190.93
    ethylene carbonate 230.47
    cyrene 91.13
    2-ethoxyethyl acetate 270.93
    2-ethylhexyl acetate 211.44
    1,2,4-trichlorobenzene 194.09
    4-methylpyridine 633.9
    dibutyl ether 147.48
    2,6-dimethyl-4-heptanol 98.0
    DEF 322.58
    dimethyl isosorbide 238.39
    tetrachloroethylene 278.18
    eugenol 131.9
    triacetin 159.05
    span 80 114.55
    1,4-butanediol 37.53
    1,1-dichloroethane 550.66
    2-methyl-1-pentanol 89.25
    methyl formate 162.57
    2-methyl-1-butanol 258.83
    n-decane 13.75
    butyronitrile 633.22
    3,7-dimethyl-1-octanol 84.97
    1-chlorooctane 50.57
    1-chlorotetradecane 20.72
    n-nonane 12.38
    undecane 9.6
    tert-butylcyclohexane 19.91
    cyclooctane 44.5
    cyclopentanol 203.12
    tetrahydropyran 1576.71
    tert-amyl methyl ether 215.42
    2,5,8-trioxanonane 299.47
    1-hexene 83.59
    2-isopropoxyethanol 138.97
    2,2,2-trifluoroethanol 44.75
    methyl butyrate 195.63

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction