Aminolevulinic acid phosphate

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  • Identifiers

    CAS number
    868074-65-1

    Molecular formula
    C5H12NO7P

    SMILES
    C(CC(=O)O)C(=O)CN.OP(=O)(O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 61.77%
    Savory 33.73%
    Sweet 30.58%
    Meaty 29.1%
    Buttery 25.14%
    Caramellic 20.83%
    Cooked 20.73%
    Milky 20.25%
    Sour 19.82%
    Fishy 19.51%

     

    Flavor
    Odorless 62.14%
    Sour 33.4%
    Very mild 27.44%
    Mild 27.05%
    Acidic 26.87%
    Yeast 23.45%
    Nutty 22.7%
    Faint 22.11%
    Caramellic 21.38%
    Musty 21.37%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.34 (neutral)

    Molecular weight
    229.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    315°C

    Flash point

    • 157.96 ˚C est.

  • Synonyms

    • Aminolevulinic acid phosphate
    • 868074-65-1
    • 5-Aminolevulinic acid phosphate
    • Pentanoic acid, 5-amino-4-oxo-, phosphate (1:1)
    • UNII-FM8DCR39GH
    • FM8DCR39GH
    • delta-Aminolevulinic acid phosphate
    • Aminolevulinic acid phosphate [INCI]
    • DTXSID70235827
    • .DELTA.-AMINOLEVULINIC ACID PHOSPHATE
    • AMINOLEVULINIC ACID PHOSPHATE [WHO-DD]
    • RefChem:112045
    • DTXCID00158318
    • 5-Amino-4-oxopentanoic acid phosphate
    • 5-amino-4-oxopentanoic acid;phosphoric acid
    • C5H12NO7P
    • SCHEMBL2113147
    • DB-413499
    • NS00078480
    • 5-amino-4-oxo-pentanoic acid;phosphoric acid
    • E85291
    • 5-Amino-4-oxopentanoic acid--phosphoric acid (1/1)
    • Q27278077
    • 5-Aminolevulinic acid phosphate, Aminolevulinic acid phosphate, delta-Aminolevulinic acid phosphate
    • 868074-65-1

  • Applications

    Aminolevulinic acid phosphate (CAS 868074-65-1) is primarily used as a chemical building block and intermediate in organic synthesis. It serves as a precursor for the synthesis of porphyrin and heme-like derivatives, supporting research and development in dyes and pigments, coatings and inks, and electronic/optoelectronic materials for industrial manufacturing. The water-soluble phosphate salt facilitates formulation work and scalable processing, and it is commonly evaluated as a plant biology tool and a potential chlorophyll precursor in agricultural studies. In polymer and materials science, it provides a source of amino functionality and is used as a feedstock for functionalized polymers and bio-inspired materials in laboratory settings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 17.2
    methanol 31.75
    isopropanol 8.78
    water 157.78
    ethyl acetate 2.84
    n-propanol 9.21
    acetone 9.63
    n-butanol 8.21
    acetonitrile 5.2
    DMF 229.57
    toluene 0.77
    isobutanol 5.86
    1,4-dioxane 34.3
    methyl acetate 3.76
    THF 20.46
    2-butanone 4.74
    n-pentanol 4.56
    sec-butanol 5.67
    n-hexane 0.88
    ethylene glycol 30.01
    NMP 151.25
    cyclohexane 1.43
    DMSO 106.12
    n-butyl acetate 1.93
    n-octanol 2.7
    chloroform 0.88
    n-propyl acetate 1.7
    acetic acid 31.07
    dichloromethane 2.02
    cyclohexanone 14.08
    propylene glycol 19.7
    isopropyl acetate 2.09
    DMAc 141.52
    2-ethoxyethanol 20.24
    isopentanol 6.08
    n-heptane 0.82
    ethyl formate 10.2
    1,2-dichloroethane 2.37
    n-hexanol 3.44
    2-methoxyethanol 53.08
    isobutyl acetate 0.98
    tetrachloromethane 0.52
    n-pentyl acetate 2.03
    transcutol 25.68
    n-heptanol 3.28
    ethylbenzene 0.91
    MIBK 2.43
    2-propoxyethanol 13.99
    tert-butanol 9.16
    MTBE 3.4
    2-butoxyethanol 12.2
    propionic acid 11.69
    o-xylene 1.92
    formic acid 85.7
    diethyl ether 3.49
    m-xylene 1.05
    p-xylene 1.46
    chlorobenzene 0.79
    dimethyl carbonate 5.13
    n-octane 0.42
    formamide 74.22
    cyclopentanone 17.57
    2-pentanone 3.87
    anisole 2.81
    cyclopentyl methyl ether 6.7
    gamma-butyrolactone 27.01
    1-methoxy-2-propanol 23.84
    pyridine 6.67
    3-pentanone 3.33
    furfural 34.72
    n-dodecane 0.26
    diethylene glycol 26.07
    diisopropyl ether 1.06
    tert-amyl alcohol 6.91
    acetylacetone 6.28
    n-hexadecane 0.28
    acetophenone 4.16
    methyl propionate 4.52
    isopentyl acetate 2.04
    trichloroethylene 1.95
    n-nonanol 2.72
    cyclohexanol 7.29
    benzyl alcohol 4.71
    2-ethylhexanol 2.21
    isooctanol 2.53
    dipropyl ether 2.49
    1,2-dichlorobenzene 1.18
    ethyl lactate 4.32
    propylene carbonate 11.64
    n-methylformamide 54.17
    2-pentanol 3.38
    n-pentane 0.72
    1-propoxy-2-propanol 7.61
    1-methoxy-2-propyl acetate 4.21
    2-(2-methoxypropoxy) propanol 12.91
    mesitylene 1.11
    ε-caprolactone 14.69
    p-cymene 1.05
    epichlorohydrin 12.85
    1,1,1-trichloroethane 0.71
    2-aminoethanol 31.92
    morpholine-4-carbaldehyde 111.28
    sulfolane 53.99
    2,2,4-trimethylpentane 0.3
    2-methyltetrahydrofuran 9.87
    n-hexyl acetate 3.0
    isooctane 0.17
    2-(2-butoxyethoxy)ethanol 16.39
    sec-butyl acetate 1.18
    tert-butyl acetate 2.6
    decalin 0.5
    glycerin 52.15
    diglyme 28.3
    acrylic acid 16.55
    isopropyl myristate 1.39
    n-butyric acid 10.46
    acetyl acetate 2.81
    di(2-ethylhexyl) phthalate 3.54
    ethyl propionate 2.31
    nitromethane 31.09
    1,2-diethoxyethane 4.68
    benzonitrile 3.22
    trioctyl phosphate 2.34
    1-bromopropane 1.06
    gamma-valerolactone 49.71
    n-decanol 2.14
    triethyl phosphate 2.92
    4-methyl-2-pentanol 2.04
    propionitrile 3.09
    vinylene carbonate 11.34
    1,1,2-trichlorotrifluoroethane 18.5
    DMS 3.83
    cumene 1.01
    2-octanol 1.78
    2-hexanone 2.3
    octyl acetate 2.22
    limonene 1.44
    1,2-dimethoxyethane 29.84
    ethyl orthosilicate 2.76
    tributyl phosphate 2.47
    diacetone alcohol 8.1
    N,N-dimethylaniline 4.21
    acrylonitrile 5.79
    aniline 2.86
    1,3-propanediol 31.06
    bromobenzene 0.53
    dibromomethane 1.1
    1,1,2,2-tetrachloroethane 2.35
    2-methyl-cyclohexyl acetate 2.84
    tetrabutyl urea 5.38
    diisobutyl methanol 1.61
    2-phenylethanol 3.49
    styrene 0.79
    dioctyl adipate 3.23
    dimethyl sulfate 14.64
    ethyl butyrate 2.45
    methyl lactate 11.5
    butyl lactate 4.53
    diethyl carbonate 2.05
    propanediol butyl ether 12.73
    triethyl orthoformate 2.97
    p-tert-butyltoluene 0.97
    methyl 4-tert-butylbenzoate 7.13
    morpholine 36.51
    tert-butylamine 3.85
    n-dodecanol 1.68
    dimethoxymethane 26.65
    ethylene carbonate 9.51
    cyrene 20.61
    2-ethoxyethyl acetate 3.73
    2-ethylhexyl acetate 1.57
    1,2,4-trichlorobenzene 1.5
    4-methylpyridine 6.1
    dibutyl ether 1.93
    2,6-dimethyl-4-heptanol 1.61
    DEF 22.52
    dimethyl isosorbide 16.63
    tetrachloroethylene 2.15
    eugenol 8.96
    triacetin 5.15
    span 80 10.67
    1,4-butanediol 13.51
    1,1-dichloroethane 0.89
    2-methyl-1-pentanol 4.05
    methyl formate 32.51
    2-methyl-1-butanol 6.01
    n-decane 0.41
    butyronitrile 3.89
    3,7-dimethyl-1-octanol 2.04
    1-chlorooctane 0.8
    1-chlorotetradecane 0.46
    n-nonane 0.42
    undecane 0.32
    tert-butylcyclohexane 0.33
    cyclooctane 0.71
    cyclopentanol 10.56
    tetrahydropyran 9.09
    tert-amyl methyl ether 3.36
    2,5,8-trioxanonane 24.93
    1-hexene 1.35
    2-isopropoxyethanol 9.21
    2,2,2-trifluoroethanol 18.29
    methyl butyrate 4.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction