alpha-Boswellic acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    471-66-9

    Molecular formula
    C30H48O3

    SMILES
    C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)O)C)C)[C@@H]1CC(CC2)(C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 86.16%
    Amber 58.87%
    Dry 53.39%
    Cedar 49.27%
    Musk 43.5%
    Sandalwood 42.7%
    Balsamic 40.83%
    Vetiver 34.91%
    Spicy 33.76%
    Powdery 31.73%

     

    Flavor
    Woody 68.89%
    Camphor 50.31%
    Pine 45.83%
    Sweet 41.14%
    Balsam 40.67%
    Herbal 36.03%
    Earthy 35.79%
    Dry 34.28%
    Spicy 29.83%
    Earth 29.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.4

    pKa est.
    6.2 (neutral)

    Molecular weight
    456.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    509°C

    Flash point

    • 263.71 ˚C est.

  • Synonyms

    • alpha-Boswellic acid
    • 471-66-9
    • (4R)-3alpha-Hydroxyolean-12-en-24-oic acid
    • RefChem:915490
    • CHEMBL395428
    • a-Boswellic acid
    • (3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
    • MFCD03788779
    • alpha -Boswellic acid
    • -Boswellic acid
    • Boswellic acid, alpha
    • (3alpha,4beta)-3-Hydroxyolean-12-en-23-oic Acid
    • SCHEMBL4379676
    • alpha-Boswellic acid (Standard)
    • HY-N0611R
    • BZXULBWGROURAF-IKNLXHIFSA-N
    • CHEBI:228850
    • HY-N0611
    • BDBM50237598
    • s5391
    • AKOS032962053
    • CCG-269302
    • CS-3735
    • FB76685
    • LMPR0106150027
    • alpha-Boswellic acid, analytical standard
    • AC-34683
    • DA-50352
    • Q63392254
    • 471-66-9

  • Applications

    alpha-Boswellic acid (CAS 471-66-9) is a pentacyclic triterpene derived from Boswellia resin. In cosmetics and personal care, it is evaluated as a bioactive constituent in skin-care formulations. In pharmaceuticals and nutraceuticals, it is studied for anti-inflammatory activity and may appear in standardized Boswellia extracts or dietary supplement blends, within relevant regulatory frameworks. In analytical and quality-control workflows, it serves as a chemical marker for authenticity and standardization of Boswellia resins and extracts. In chemical research and development, it can function as a reference compound and starting point for derivatization and exploration of related triterpenes.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.87
    methanol 7.23
    isopropanol 13.27
    water 0.0
    ethyl acetate 6.3
    n-propanol 19.25
    acetone 8.99
    n-butanol 17.07
    acetonitrile 2.04
    DMF 52.52
    toluene 10.33
    isobutanol 13.2
    1,4-dioxane 32.31
    methyl acetate 5.09
    THF 74.21
    2-butanone 13.38
    n-pentanol 12.01
    sec-butanol 9.73
    n-hexane 0.5
    ethylene glycol 0.81
    NMP 26.24
    cyclohexane 0.5
    DMSO 13.45
    n-butyl acetate 8.21
    n-octanol 6.79
    chloroform 19.91
    n-propyl acetate 5.51
    acetic acid 4.02
    dichloromethane 9.33
    cyclohexanone 18.6
    propylene glycol 2.98
    isopropyl acetate 6.96
    DMAc 33.68
    2-ethoxyethanol 16.94
    isopentanol 11.28
    n-heptane 0.44
    ethyl formate 3.21
    1,2-dichloroethane 6.98
    n-hexanol 13.38
    2-methoxyethanol 24.09
    isobutyl acetate 6.08
    tetrachloromethane 2.89
    n-pentyl acetate 12.54
    transcutol 34.18
    n-heptanol 11.19
    ethylbenzene 4.91
    MIBK 9.18
    2-propoxyethanol 44.53
    tert-butanol 9.42
    MTBE 8.72
    2-butoxyethanol 29.42
    propionic acid 4.24
    o-xylene 5.03
    formic acid 1.45
    diethyl ether 10.92
    m-xylene 6.94
    p-xylene 4.93
    chlorobenzene 7.09
    dimethyl carbonate 5.03
    n-octane 0.2
    formamide 2.37
    cyclopentanone 26.05
    2-pentanone 12.15
    anisole 11.28
    cyclopentyl methyl ether 17.3
    gamma-butyrolactone 16.63
    1-methoxy-2-propanol 32.14
    pyridine 23.81
    3-pentanone 9.02
    furfural 13.14
    n-dodecane 0.09
    diethylene glycol 14.91
    diisopropyl ether 2.93
    tert-amyl alcohol 7.06
    acetylacetone 10.64
    n-hexadecane 0.12
    acetophenone 9.4
    methyl propionate 8.58
    isopentyl acetate 10.33
    trichloroethylene 16.17
    n-nonanol 7.65
    cyclohexanol 7.91
    benzyl alcohol 10.79
    2-ethylhexanol 5.91
    isooctanol 8.54
    dipropyl ether 7.79
    1,2-dichlorobenzene 5.95
    ethyl lactate 4.62
    propylene carbonate 6.53
    n-methylformamide 9.92
    2-pentanol 8.44
    n-pentane 0.55
    1-propoxy-2-propanol 30.64
    1-methoxy-2-propyl acetate 17.76
    2-(2-methoxypropoxy) propanol 17.32
    mesitylene 3.77
    ε-caprolactone 14.57
    p-cymene 3.23
    epichlorohydrin 24.02
    1,1,1-trichloroethane 6.37
    2-aminoethanol 4.76
    morpholine-4-carbaldehyde 40.32
    sulfolane 18.23
    2,2,4-trimethylpentane 0.38
    2-methyltetrahydrofuran 18.71
    n-hexyl acetate 13.42
    isooctane 0.38
    2-(2-butoxyethoxy)ethanol 25.4
    sec-butyl acetate 4.9
    tert-butyl acetate 8.78
    decalin 0.49
    glycerin 4.6
    diglyme 38.16
    acrylic acid 3.35
    isopropyl myristate 3.99
    n-butyric acid 8.48
    acetyl acetate 3.93
    di(2-ethylhexyl) phthalate 6.6
    ethyl propionate 5.28
    nitromethane 6.09
    1,2-diethoxyethane 12.79
    benzonitrile 6.5
    trioctyl phosphate 4.78
    1-bromopropane 5.27
    gamma-valerolactone 40.92
    n-decanol 4.0
    triethyl phosphate 3.74
    4-methyl-2-pentanol 5.52
    propionitrile 5.07
    vinylene carbonate 7.09
    1,1,2-trichlorotrifluoroethane 15.62
    DMS 7.62
    cumene 3.29
    2-octanol 5.58
    2-hexanone 9.38
    octyl acetate 5.8
    limonene 3.52
    1,2-dimethoxyethane 25.75
    ethyl orthosilicate 4.38
    tributyl phosphate 3.79
    diacetone alcohol 12.36
    N,N-dimethylaniline 9.44
    acrylonitrile 5.25
    aniline 10.4
    1,3-propanediol 10.49
    bromobenzene 6.73
    dibromomethane 6.99
    1,1,2,2-tetrachloroethane 14.97
    2-methyl-cyclohexyl acetate 7.59
    tetrabutyl urea 6.71
    diisobutyl methanol 3.72
    2-phenylethanol 14.7
    styrene 4.9
    dioctyl adipate 6.54
    dimethyl sulfate 7.16
    ethyl butyrate 5.62
    methyl lactate 6.88
    butyl lactate 12.84
    diethyl carbonate 3.17
    propanediol butyl ether 19.16
    triethyl orthoformate 6.73
    p-tert-butyltoluene 3.46
    methyl 4-tert-butylbenzoate 15.72
    morpholine 48.35
    tert-butylamine 4.82
    n-dodecanol 2.0
    dimethoxymethane 35.99
    ethylene carbonate 6.0
    cyrene 15.94
    2-ethoxyethyl acetate 18.21
    2-ethylhexyl acetate 8.0
    1,2,4-trichlorobenzene 8.79
    4-methylpyridine 18.35
    dibutyl ether 3.91
    2,6-dimethyl-4-heptanol 3.72
    DEF 13.6
    dimethyl isosorbide 26.23
    tetrachloroethylene 9.86
    eugenol 17.87
    triacetin 10.23
    span 80 15.02
    1,4-butanediol 3.83
    1,1-dichloroethane 6.5
    2-methyl-1-pentanol 8.0
    methyl formate 5.2
    2-methyl-1-butanol 10.51
    n-decane 0.28
    butyronitrile 6.34
    3,7-dimethyl-1-octanol 5.18
    1-chlorooctane 1.94
    1-chlorotetradecane 0.43
    n-nonane 0.24
    undecane 0.15
    tert-butylcyclohexane 0.55
    cyclooctane 0.27
    cyclopentanol 10.07
    tetrahydropyran 24.95
    tert-amyl methyl ether 6.4
    2,5,8-trioxanonane 21.44
    1-hexene 2.4
    2-isopropoxyethanol 12.89
    2,2,2-trifluoroethanol 1.6
    methyl butyrate 6.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction