Alcloxa

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  • Identifiers

    CAS number
    1317-25-5

    Molecular formula
    C4H9Al2ClN4O7

    SMILES
    C1(C(=O)NC(=N1)[O-])NC(=O)N.[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 80.18%
    Savory 24.6%
    Cooked 17.95%
    Meaty 17.69%
    Fishy 16.91%
    Cooling 16.37%
    Sweet 15.37%
    Burnt 14.85%
    Popcorn 14.03%
    Bitter 13.86%

     

    Flavor
    Bitter 59.4%
    Odorless 46.43%
    Very mild 22.66%
    Bland 21.0%
    Roasted 19.92%
    Yeast 19.88%
    Nitrile 19.73%
    Taco 19.57%
    Sweet-like 19.34%
    Bread crust 19.27%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.78 (neutral)

    Molecular weight
    314.55 g/mol

    Flash point

    • 186.9 ˚C est.

  • Synonyms

    • ALCLOXA
    • ALCA
    • Allantolox
    • Alcloxum
    • Aluminum chlorhydroxy allantoinate
    • Aluminum chlorohydroxy allantoinate
    • 18B8O9DQA2
    • Chlorhydroxyaluminum allantoinate
    • Caswell No. 029A
    • RC-173
    • UNII-18B8O9DQA2
    • Dialuminum tetrahydroxychloro allantoinate
    • EINECS 215-262-3
    • Alcloxum (INN-Latin)
    • Alcloxum [INN-Latin]
    • ALUMINIUM CHLORHYDROXY ALLANTOINATE
    • ALUMINIUM CHLOROHYDROXY ALLANTOINATE
    • ALCLOXA (MART.)
    • ALCLOXA [MART.]
    • Aluminum, chlorotetrahydroxy((4,5-dihydro-2-hydroxy-5-oxo-1H-imidazol-4-yl)ureato)di-
    • Chloro((2,5-dioxo-4-imidazolidinyl)ureato)tetrahydroxydialuminum
    • Aluminum, chloro((2,5-dioxo-4-imidazolidinyl)ureato)tetrahydroxydi-
    • Aluminum, chlorotetrahydroxy((2-hydroxy-5-oxo-2-imidazolin-4-yl)ureato)di-
    • Chlorotetrahydroxy((2-hydroxy-5-oxo-2-imidazolin-4-yl)ureato)dialuminum
    • CHLOROTETRAHYDROXY((2-HYDROXY-5-OXO-2-IMIDAZOLIN-4-YL)UREATO)DIALUMINIUM
    • ALUMINIUM, CHLOROTETRAHYDROXY((4,5-DIHYDRO-2-HYDROXY-5-OXO-1H-IMIDAZOL-4-YL)UREATO)DI-
    • ALUMINUM CHLORHYDROXY ALLANTOINATE (II)
    • ALUMINUM CHLORHYDROXY ALLANTOINATE [II]
    • Chlorotetrahydroxy[(2-hydroxy-5-oxo-2-imidazolin-4-yl)ureato]dialuminum
    • Exoden Cure Powder
    • RefChem:58170
    • Chlorotetra hydroxy((2-hydroxy-5-oxo-2-imidazolin-4-yl)ureato)dialuminium
    • 215-262-3
    • 1317-25-5
    • Aluminium chlorohydroxyallantoinate
    • Alcloxa [USAN:INN]
    • ALCLOXA [VANDF]
    • ALCLOXA [USAN]
    • ALCLOXA [INN]
    • ALCLOXA [JAN]
    • ALCLOXA [WHO-DD]
    • orb1986582
    • EBC-26759
    • AKOS040750303
    • DB11205
    • Q27891170
    • Aluminum, chloro(N-(2,5-dioxo-4-imidazolidinyl)ureato)tetrahydroxydi-
    • 1317-25-5

  • Applications

    Alcloxa (CAS 1317-25-5) is commonly evaluated and used as an antimicrobial preservative and stabilizing additive in cosmetic and personal care formulations, including skin care, hair care, and deodorants; it may also be employed in topical pharmaceuticals as a preservative or excipient, and can appear in household cleaning formulations as an antimicrobial component; in industrial manufacturing it can serve as an intermediate or processing aid under appropriate regulatory controls, and it may be used in coatings and inks as an additive where antimicrobial or stabilizing properties are desired.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.51
    methanol 2.3
    isopropanol 0.23
    water 6.31
    ethyl acetate 0.2
    n-propanol 0.29
    acetone 0.36
    n-butanol 0.18
    acetonitrile 0.36
    DMF 22.95
    toluene 0.06
    isobutanol 0.16
    1,4-dioxane 0.89
    methyl acetate 0.44
    THF 1.29
    2-butanone 0.29
    n-pentanol 0.13
    sec-butanol 0.18
    n-hexane 0.02
    ethylene glycol 2.47
    NMP 20.55
    cyclohexane 0.02
    DMSO 32.28
    n-butyl acetate 0.31
    n-octanol 0.12
    chloroform 0.11
    n-propyl acetate 0.25
    acetic acid 1.13
    dichloromethane 0.22
    cyclohexanone 0.56
    propylene glycol 1.5
    isopropyl acetate 0.13
    DMAc 18.62
    2-ethoxyethanol 1.91
    isopentanol 0.14
    n-heptane 0.02
    ethyl formate 1.1
    1,2-dichloroethane 0.14
    n-hexanol 0.14
    2-methoxyethanol 5.25
    isobutyl acetate 0.11
    tetrachloromethane 0.05
    n-pentyl acetate 0.16
    transcutol 1.53
    n-heptanol 0.15
    ethylbenzene 0.06
    MIBK 0.14
    2-propoxyethanol 2.14
    tert-butanol 0.2
    MTBE 0.09
    2-butoxyethanol 1.34
    propionic acid 0.71
    o-xylene 0.09
    formic acid 10.1
    diethyl ether 0.13
    m-xylene 0.06
    p-xylene 0.1
    chlorobenzene 0.04
    dimethyl carbonate 1.32
    n-octane 0.01
    formamide 10.66
    cyclopentanone 1.06
    2-pentanone 0.2
    anisole 0.2
    cyclopentyl methyl ether 0.32
    gamma-butyrolactone 2.58
    1-methoxy-2-propanol 2.32
    pyridine 0.6
    3-pentanone 0.22
    furfural 5.2
    n-dodecane 0.01
    diethylene glycol 4.81
    diisopropyl ether 0.03
    tert-amyl alcohol 0.19
    acetylacetone 0.44
    n-hexadecane 0.01
    acetophenone 0.36
    methyl propionate 0.56
    isopentyl acetate 0.24
    trichloroethylene 0.19
    n-nonanol 0.12
    cyclohexanol 0.16
    benzyl alcohol 0.28
    2-ethylhexanol 0.1
    isooctanol 0.1
    dipropyl ether 0.21
    1,2-dichlorobenzene 0.06
    ethyl lactate 0.89
    propylene carbonate 1.47
    n-methylformamide 7.59
    2-pentanol 0.09
    n-pentane 0.01
    1-propoxy-2-propanol 1.15
    1-methoxy-2-propyl acetate 0.76
    2-(2-methoxypropoxy) propanol 1.46
    mesitylene 0.05
    ε-caprolactone 0.86
    p-cymene 0.07
    epichlorohydrin 1.17
    1,1,1-trichloroethane 0.05
    2-aminoethanol 1.97
    morpholine-4-carbaldehyde 13.87
    sulfolane 7.68
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.38
    n-hexyl acetate 0.18
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 1.39
    sec-butyl acetate 0.11
    tert-butyl acetate 0.14
    decalin 0.01
    glycerin 6.3
    diglyme 3.37
    acrylic acid 1.41
    isopropyl myristate 0.07
    n-butyric acid 0.45
    acetyl acetate 0.19
    di(2-ethylhexyl) phthalate 0.26
    ethyl propionate 0.31
    nitromethane 3.74
    1,2-diethoxyethane 0.27
    benzonitrile 0.26
    trioctyl phosphate 0.19
    1-bromopropane 0.07
    gamma-valerolactone 4.41
    n-decanol 0.09
    triethyl phosphate 0.48
    4-methyl-2-pentanol 0.06
    propionitrile 0.29
    vinylene carbonate 1.58
    1,1,2-trichlorotrifluoroethane 3.64
    DMS 0.45
    cumene 0.05
    2-octanol 0.08
    2-hexanone 0.2
    octyl acetate 0.12
    limonene 0.07
    1,2-dimethoxyethane 3.62
    ethyl orthosilicate 0.34
    tributyl phosphate 0.22
    diacetone alcohol 0.55
    N,N-dimethylaniline 0.33
    acrylonitrile 0.69
    aniline 0.17
    1,3-propanediol 1.42
    bromobenzene 0.03
    dibromomethane 0.11
    1,1,2,2-tetrachloroethane 0.21
    2-methyl-cyclohexyl acetate 0.24
    tetrabutyl urea 0.51
    diisobutyl methanol 0.07
    2-phenylethanol 0.26
    styrene 0.06
    dioctyl adipate 0.19
    dimethyl sulfate 4.68
    ethyl butyrate 0.35
    methyl lactate 2.44
    butyl lactate 0.66
    diethyl carbonate 0.38
    propanediol butyl ether 1.23
    triethyl orthoformate 0.41
    p-tert-butyltoluene 0.06
    methyl 4-tert-butylbenzoate 0.66
    morpholine 1.41
    tert-butylamine 0.08
    n-dodecanol 0.07
    dimethoxymethane 3.68
    ethylene carbonate 1.06
    cyrene 2.76
    2-ethoxyethyl acetate 0.32
    2-ethylhexyl acetate 0.19
    1,2,4-trichlorobenzene 0.1
    4-methylpyridine 0.54
    dibutyl ether 0.1
    2,6-dimethyl-4-heptanol 0.07
    DEF 1.53
    dimethyl isosorbide 2.59
    tetrachloroethylene 0.17
    eugenol 1.09
    triacetin 0.45
    span 80 0.8
    1,4-butanediol 0.64
    1,1-dichloroethane 0.06
    2-methyl-1-pentanol 0.1
    methyl formate 5.84
    2-methyl-1-butanol 0.15
    n-decane 0.01
    butyronitrile 0.22
    3,7-dimethyl-1-octanol 0.08
    1-chlorooctane 0.03
    1-chlorotetradecane 0.02
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.01
    cyclopentanol 0.3
    tetrahydropyran 0.23
    tert-amyl methyl ether 0.12
    2,5,8-trioxanonane 2.56
    1-hexene 0.05
    2-isopropoxyethanol 0.68
    2,2,2-trifluoroethanol 2.02
    methyl butyrate 0.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction