Ajoene

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  • Identifiers

    CAS number
    92285-01-3

    Molecular formula
    C9H14OS3

    SMILES
    C=CCSS/C=C/CS(=O)CC=C

    Safety labels

  • Properties

    XLogP3-AA
    1.7

    Molecular weight
    234.4 g/mol

  • Synonyms

    • Ajoene
    • 92285-01-3
    • (E)-1-(prop-2-enyldisulfanyl)-3-prop-2-enylsulfinylprop-1-ene
    • Disulfide, 2-propenyl 3-(2-propenylsulfinyl)-1-propenyl
    • 99A0041VG8
    • RefChem:915317
    • 3-(((1Z)-3-(prop-2-ene-1-sulfinyl)prop-1-en-1-yl)disulfanyl)prop-1-ene
    • 2-PROPEN-1-YL (3-(2-PROPEN-1-YLSULFINYL)-1-PROPEN-1-YL) DISULFIDE
    • (E)-Ajoene
    • 92284-99-6
    • Ajoene, (E)-
    • trans-Ajoene
    • E-Ajoene
    • NSC614554
    • NSC-614554
    • W36UK64JYA
    • CHEMBL122890
    • Disulfide, 2-propen-1-yl (1E)-3-(2-propen-1-ylsulfinyl)-1-propen-1-yl
    • CIS-4,5,9-TRITHIADODECA-1,6,11-TRIENE-9-
    • Ajoene (not validated)
    • Disulfide, 2-propenyl (1E)-3-(2-propenylsulfinyl)-1-propenyl
    • Disulfide, 2-propenyl 3-(2-propenylsulfinyl)-1-propenyl, (E)-
    • E/Z Ajoene (~20per cent in Ethyl Acetate)
    • (E)-1-(allyldisulfanyl)-3-allylsulfinyl-prop-1-ene
    • 2-Propen-1-yl[3-(2-propen-1-ylsulfinyl)-1-propen-1-yl] disulfide
    • Disulfide, 2-propen-1-yl [3-(2-propen-1-ylsulfinyl)-1-propen-1-yl]
    • E- Ajoene (~20% in Ethyl Acetate)
    • UNII-W36UK64JYA
    • NSC 614554
    • C9H14OS3
    • UNII-99A0041VG8
    • Ajoene, trans-
    • 2-Propen-1-yl [3-(2-propen-1-ylsulfinyl)-1-propen-1-yl]disulfide; 2-Propenyl 3-(2-propenylsulfinyl)-1-propenyl disulfide; Acuagel; Adjoen; Ajoene
    • 2-Propenyl-3-(2-propenylsulfinyl)-1-propenyl disulfide
    • SCHEMBL465526
    • orb1693729
    • AJOENE (E)-FORM [MI]
    • CHEBI:80708
    • DTXSID501318485
    • BDBM50240785
    • MFCD06411561
    • AKOS040754739
    • AKOS040755267
    • HY-106784A
    • DA-69163
    • DA-70655
    • HY-106784
    • CS-0026551
    • CS-0173650
    • E-4,5,9-trithiadodeca-1,6,11-triene 9-oxide
    • Q338762
    • (e,z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide
    • (E)-1-allyl-2-(3-(allylsulfinyl)prop-1-enyl)disulfane
    • (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sulfinyl)-propene
    • (E)-1-Allyl-2-(3-(allylsulfinyl)prop-1-en-1-yl)disulfane
    • (1E)-3-(Prop-2-ene-1-sulfinyl)-1-[(prop-2-en-1-yl)disulfanyl]prop-1-ene
    • 92285-01-3

  • Applications

    Ajoene (CAS 92285-01-3) is an organosulfur compound derived from garlic that is primarily encountered in research as a bioactive antimicrobial agent. In pharmaceuticals and life-science research, it is commonly evaluated as an antimicrobial lead compound and a reference natural product of sulfur chemistry. In agriculture, it is studied for crop-protection formulations due to its antimicrobial properties. In cosmetics and personal care, it is examined for topical antimicrobial activity in early-stage formulation work. In cleaning and household products, it may be evaluated as an antimicrobial additive compatible with surface cleaners. In coatings and inks, it is explored as a potential antimicrobial supplement in specialty coatings. In industrial manufacturing, its use is mainly at the research and development stage as a building block for sulfur-containing compounds rather than a widely adopted commercial ingredient. Subject to local regulations and formulation constraints.

    gpt-5-nano

1 3

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction