Adipic Dihydrazide

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  • Identifiers

    CAS number
    1071-93-8

    Molecular formula
    C6H14N4O2

    SMILES
    C(CCC(=O)NN)CC(=O)NN

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 56.66%
    Fishy 43.1%
    Savory 36.53%
    Meaty 26.9%
    Sweet 24.5%
    Cooling 21.5%
    Cheesy 19.22%
    Cooked 18.76%
    Pungent 18.6%
    Ripe 17.43%

     

    Flavor
    Odorless 54.48%
    Bitter 30.15%
    Mild 27.85%
    Bland 26.75%
    Roasted 22.69%
    Cooked 22.5%
    Sweet-like 21.81%
    Faint 21.31%
    Yeast 21.04%
    Sulfury 19.79%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.1

    pKa est.
    7.28 (neutral)

    Molecular weight
    174.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    250°C

    Flash point

    • 219.74 ˚C est.

  • Synonyms

    • Adipic dihydrazide
    • 1071-93-8
    • Adipic acid dihydrazide
    • Hexanedioic acid, dihydrazide
    • adipic hydrazide
    • VK98I9YW5M
    • AJICURE ADH
    • QUALIMER ADH
    • NSC-3378
    • ULTRALINK HYDRAZIDE
    • NSC-29542
    • NSC3378
    • BK 1000Z
    • BT 1000Z
    • NSC29542
    • T 2210
    • RefChem:553051
    • 213-999-5
    • Adipohydrazide
    • Hexanedihydrazide
    • Adipodihydrazide
    • Adipic acid, dihydrazide
    • MFCD00007614
    • Adipoyldihydrazine
    • adipoyl dihydrazide
    • DTXSID0044361
    • Adipyl hydrazide
    • Hexanedioic acid, 1,6-dihydrazide
    • WLN: ZMV4VMZ
    • butane-1,4-dicarbohydrazide
    • Hexanedioic acid dihydrazide
    • Adip dihydr
    • Adipoyl hydrazide
    • adipic dihydrazone
    • Hexanedihydrazide #
    • NSC 3378
    • EINECS 213-999-5
    • NSC 29542
    • Adipic acid dihyrazide
    • Hexanedioic dihydrazide
    • AI3-22640
    • UNII-VK98I9YW5M
    • EC 213-999-5
    • SCHEMBL49856
    • orb3025946
    • orb3029105
    • CHEMBL3185968
    • DTXCID8024361
    • 1,4-Butanedicarboxylic dihydrazide
    • ALBB-011767
    • BB_SC-00094
    • STR02658
    • Tox21_301067
    • BBL022965
    • SBB038773
    • STK709135
    • AKOS000267183
    • FA36749
    • NCGC00248276-01
    • NCGC00257525-01
    • CAS-1071-93-8
    • DB-022418
    • A0170
    • Adipic acid dihydrazide, >=98% (titration)
    • CS-0010116
    • NS00003709
    • ST45027596
    • EN300-03706
    • D72486
    • Adipic acid dihydrazide, purum, >=97.0% (NT)
    • F018159
    • Q4682936
    • Z56812730
    • F1943-0024
    • InChI=1/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12
    • 1071-93-8

  • Applications

    Adipic Dihydrazide (1071-93-8) is widely used as a curing and crosslinking agent for epoxy resins, delivering enhanced chemical resistance and thermal stability in coatings, adhesives, and composite systems. As a bifunctional hydrazide, it enables robust network formation and can act as a crosslinker in epoxy and polyurethane formulations. It is also employed as a building block for hydrazide-based crosslinkers in advanced polymers, including polyurethanes and polyimides, to tailor cure behavior and mechanical properties. Additionally, it is used as an intermediate in the synthesis of specialty resins and functional polymers for electronics encapsulation and high-temperature coatings. Its use is formulation-dependent and subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.53
    methanol 11.85
    isopropanol 0.89
    water 58.22
    ethyl acetate 0.26
    n-propanol 1.16
    acetone 0.89
    n-butanol 0.73
    acetonitrile 0.7
    DMF 15.99
    toluene 0.1
    isobutanol 0.7
    1,4-dioxane 1.1
    methyl acetate 0.44
    THF 1.54
    2-butanone 0.67
    n-pentanol 0.6
    sec-butanol 0.61
    n-hexane 0.05
    ethylene glycol 9.29
    NMP 25.87
    cyclohexane 0.04
    DMSO 71.12
    n-butyl acetate 0.38
    n-octanol 0.43
    chloroform 0.43
    n-propyl acetate 0.26
    acetic acid 11.65
    dichloromethane 0.48
    cyclohexanone 2.17
    propylene glycol 6.0
    isopropyl acetate 0.18
    DMAc 21.33
    2-ethoxyethanol 4.74
    isopentanol 0.66
    n-heptane 0.05
    ethyl formate 1.6
    1,2-dichloroethane 0.39
    n-hexanol 0.64
    2-methoxyethanol 11.64
    isobutyl acetate 0.16
    tetrachloromethane 0.22
    n-pentyl acetate 0.37
    transcutol 5.68
    n-heptanol 0.6
    ethylbenzene 0.11
    MIBK 0.33
    2-propoxyethanol 3.38
    tert-butanol 1.05
    MTBE 0.22
    2-butoxyethanol 2.56
    propionic acid 2.88
    o-xylene 0.23
    formic acid 54.77
    diethyl ether 0.13
    m-xylene 0.13
    p-xylene 0.2
    chlorobenzene 0.2
    dimethyl carbonate 0.49
    n-octane 0.04
    formamide 35.96
    cyclopentanone 2.94
    2-pentanone 0.38
    anisole 0.3
    cyclopentyl methyl ether 0.4
    gamma-butyrolactone 4.82
    1-methoxy-2-propanol 3.75
    pyridine 1.1
    3-pentanone 0.42
    furfural 10.84
    n-dodecane 0.02
    diethylene glycol 9.27
    diisopropyl ether 0.06
    tert-amyl alcohol 0.96
    acetylacetone 0.86
    n-hexadecane 0.03
    acetophenone 0.92
    methyl propionate 0.47
    isopentyl acetate 0.44
    trichloroethylene 0.74
    n-nonanol 0.45
    cyclohexanol 0.7
    benzyl alcohol 1.09
    2-ethylhexanol 0.41
    isooctanol 0.5
    dipropyl ether 0.21
    1,2-dichlorobenzene 0.36
    ethyl lactate 1.13
    propylene carbonate 2.34
    n-methylformamide 10.0
    2-pentanol 0.28
    n-pentane 0.03
    1-propoxy-2-propanol 1.78
    1-methoxy-2-propyl acetate 0.83
    2-(2-methoxypropoxy) propanol 3.28
    mesitylene 0.13
    ε-caprolactone 2.22
    p-cymene 0.22
    epichlorohydrin 2.02
    1,1,1-trichloroethane 0.21
    2-aminoethanol 8.61
    morpholine-4-carbaldehyde 14.64
    sulfolane 19.75
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 0.63
    n-hexyl acetate 0.48
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 3.56
    sec-butyl acetate 0.16
    tert-butyl acetate 0.3
    decalin 0.04
    glycerin 19.43
    diglyme 5.18
    acrylic acid 5.41
    isopropyl myristate 0.24
    n-butyric acid 2.12
    acetyl acetate 0.34
    di(2-ethylhexyl) phthalate 1.05
    ethyl propionate 0.28
    nitromethane 9.92
    1,2-diethoxyethane 0.54
    benzonitrile 0.77
    trioctyl phosphate 0.61
    1-bromopropane 0.14
    gamma-valerolactone 9.75
    n-decanol 0.35
    triethyl phosphate 0.72
    4-methyl-2-pentanol 0.25
    propionitrile 0.45
    vinylene carbonate 2.63
    1,1,2-trichlorotrifluoroethane 10.11
    DMS 0.72
    cumene 0.14
    2-octanol 0.3
    2-hexanone 0.4
    octyl acetate 0.36
    limonene 0.28
    1,2-dimethoxyethane 3.62
    ethyl orthosilicate 0.58
    tributyl phosphate 0.68
    diacetone alcohol 1.62
    N,N-dimethylaniline 0.53
    acrylonitrile 1.14
    aniline 0.45
    1,3-propanediol 7.32
    bromobenzene 0.14
    dibromomethane 0.31
    1,1,2,2-tetrachloroethane 0.79
    2-methyl-cyclohexyl acetate 0.68
    tetrabutyl urea 1.34
    diisobutyl methanol 0.29
    2-phenylethanol 1.02
    styrene 0.11
    dioctyl adipate 0.61
    dimethyl sulfate 2.84
    ethyl butyrate 0.39
    methyl lactate 2.56
    butyl lactate 1.35
    diethyl carbonate 0.36
    propanediol butyl ether 3.49
    triethyl orthoformate 0.5
    p-tert-butyltoluene 0.2
    methyl 4-tert-butylbenzoate 1.73
    morpholine 1.74
    tert-butylamine 0.36
    n-dodecanol 0.27
    dimethoxymethane 1.65
    ethylene carbonate 1.52
    cyrene 6.69
    2-ethoxyethyl acetate 0.74
    2-ethylhexyl acetate 0.32
    1,2,4-trichlorobenzene 0.5
    4-methylpyridine 0.76
    dibutyl ether 0.2
    2,6-dimethyl-4-heptanol 0.29
    DEF 1.56
    dimethyl isosorbide 4.58
    tetrachloroethylene 0.91
    eugenol 2.51
    triacetin 1.18
    span 80 2.75
    1,4-butanediol 3.77
    1,1-dichloroethane 0.16
    2-methyl-1-pentanol 0.62
    methyl formate 6.17
    2-methyl-1-butanol 0.68
    n-decane 0.04
    butyronitrile 0.46
    3,7-dimethyl-1-octanol 0.42
    1-chlorooctane 0.12
    1-chlorotetradecane 0.07
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.02
    cyclopentanol 1.11
    tetrahydropyran 0.34
    tert-amyl methyl ether 0.29
    2,5,8-trioxanonane 5.11
    1-hexene 0.1
    2-isopropoxyethanol 1.66
    2,2,2-trifluoroethanol 7.54
    methyl butyrate 0.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction