Adenosine 5'-monophosphate disodium

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  • Identifiers

    CAS number
    4578-31-8

    Molecular formula
    C10H12N5Na2O7P

    SMILES
    C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 89.06%
    Savory 18.53%
    Sweet 17.58%
    Bitter 16.92%
    Milky 16.1%
    Cooling 15.79%
    Cooked 14.12%
    Clean 12.93%
    Alcoholic 11.94%
    Animal 10.54%

     

    Flavor
    Bitter 60.4%
    Odorless 58.78%
    Bland 33.14%
    Sweet-like 24.73%
    Very mild 24.53%
    Mild 24.11%
    Yeast 19.56%
    Nitrile 18.98%
    Scallion 18.88%
    Bread crust 18.86%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.57 (weak acid)

    Molecular weight
    391.19 g/mol

    Flash point

    • 389.76 ˚C est.

  • Synonyms

    • 4578-31-8
    • Adenosine Phosphate Disodium
    • Disodium AMP
    • AMP disodium salt
    • Disodium 5'-AMP
    • 5'-AMP disodium salt
    • 5'-ADENYLIC ACID, DISODIUM SALT
    • Adenylic acid disodium salt
    • T1WZ11DSRN
    • DTXSID80196617
    • ADENOSINE 5'-MONOPHOSPHATE DISODIUM
    • RefChem:553008
    • DTXCID20119108
    • 224-961-2
    • Adenosine 5'-monophosphate disodium salt
    • Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate
    • Adenosine 5'-monophosphate sodium salt
    • 13474-03-8
    • MFCD00065023
    • C10H12N5Na2O7P
    • 5'-adenylic acid sodium salt
    • adenosine-5'-monophosphate disodium salt
    • 5'-ADENYLIC ACID, SODIUM SALT
    • Disodium Adenosine 5-Phosphate
    • disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
    • Disodium adenosine 5'-phosphate
    • Sodium adenosine-5'-monophosphate
    • Adenosine 5 inverted exclamation marka-monophosphate sodium salt
    • MFCD08689634
    • Adenosine 5'-Monophosphate Disodium Salt Hydrate
    • EINECS 224-961-2
    • UNII-T1WZ11DSRN
    • 5'-Adenylic acid disodium salt
    • Adenosine 5'-phosphate disodium salt
    • Adenosine-5'-Monophosphate Sodium Salt
    • 5'-AMP⋅2Na
    • AMP.2Na
    • AMP.Na2
    • DISODIUM ADENYLATE
    • Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate hydrate(x:1:x)
    • 5'-ADENYLIC ACID, SODIUM SALT (1:2)
    • Adenosine 5'-monophosphoric acid disodium salt
    • disodium adenosine phosphate
    • DISODIUM 5'-ADENYLATE
    • SCHEMBL353218
    • orb1741452
    • Adenosine 5'-phosphate disodium
    • SCHEMBL29364783
    • ADENOSINE PHOSPHATE SODIUM
    • CHEBI:81690
    • Disodium 5'-O-phosphonatoadenosine
    • Adenosine 5'-monophosphoric acid disodium salt dihydrate
    • AKOS015896932
    • NA03463
    • Adenosine 5-Monophosphate Disodium Salt
    • ADENOSINE PHOSPHATE, SODIUM SALT
    • Adenosine 5'-monophosphate, disodium salt
    • ADENOSINE PHOSPHATE SODIUM [VANDF]
    • AS-13473
    • SY066751
    • 5'-Adenylic acid,sodium salt,hydrate(9ci)
    • A51083
    • C18344
    • ADENOSINE PHOSPHATE, SODIUM SALT [WHO-DD]
    • F987762
    • Q27155558
    • Adenosine 5'-monophosphate disodium salt, >=99.0% (HPLC)
    • DISODIUM 9-(.BETA.-D-RIBOFURANOSYL)ADENINE 5'-MONOPHOSPHATE
    • disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
    • Sodium((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate
    • 4578-31-8

  • Applications

    Adenosine 5'-monophosphate disodium (CAS 4578-31-8) is primarily used as a biochemical reagent and building block in nucleotide and nucleic acid chemistry. In research and development, it serves as a substrate and intermediate in enzymatic assays and nucleotide biosynthesis, and as a source of phosphate for biochemical buffers and related media. In the pharmaceutical and biotech sector, it is employed as an excipient and reference material for analytical testing of nucleotide-containing formulations. In the food sector, AMP disodium may be evaluated as a flavor-enhancing nucleotide in blends with other 5'-nucleotides. In cosmetics and personal care, it can appear in niche nucleotide-based formulations for potential skin-conditioning effects. In industrial manufacturing, it is used as a reagent and intermediate for the production of nucleotide-derived products and analytical standards.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.23
    methanol 0.74
    isopropanol 0.23
    water 6.85
    ethyl acetate 0.08
    n-propanol 0.29
    acetone 0.18
    n-butanol 0.24
    acetonitrile 0.21
    DMF 6.2
    toluene 0.03
    isobutanol 0.17
    1,4-dioxane 0.35
    methyl acetate 0.17
    THF 0.67
    2-butanone 0.3
    n-pentanol 0.13
    sec-butanol 0.3
    n-hexane 0.01
    ethylene glycol 3.47
    NMP 27.89
    cyclohexane 0.05
    DMSO 9.89
    n-butyl acetate 0.16
    n-octanol 0.14
    chloroform 0.04
    n-propyl acetate 0.08
    acetic acid 2.62
    dichloromethane 0.05
    cyclohexanone 0.7
    propylene glycol 3.31
    isopropyl acetate 0.05
    DMAc 11.03
    2-ethoxyethanol 1.82
    isopentanol 0.16
    n-heptane 0.06
    ethyl formate 0.24
    1,2-dichloroethane 0.05
    n-hexanol 0.22
    2-methoxyethanol 5.34
    isobutyl acetate 0.03
    tetrachloromethane 0.03
    n-pentyl acetate 0.14
    transcutol 1.81
    n-heptanol 0.33
    ethylbenzene 0.02
    MIBK 0.08
    2-propoxyethanol 1.88
    tert-butanol 0.23
    MTBE 0.05
    2-butoxyethanol 1.57
    propionic acid 0.84
    o-xylene 0.06
    formic acid 28.84
    diethyl ether 0.09
    m-xylene 0.03
    p-xylene 0.03
    chlorobenzene 0.02
    dimethyl carbonate 0.4
    n-octane 0.03
    formamide 22.63
    cyclopentanone 1.17
    2-pentanone 0.17
    anisole 0.05
    cyclopentyl methyl ether 0.27
    gamma-butyrolactone 1.51
    1-methoxy-2-propanol 2.7
    pyridine 0.47
    3-pentanone 0.24
    furfural 2.75
    n-dodecane 0.01
    diethylene glycol 6.01
    diisopropyl ether 0.03
    tert-amyl alcohol 0.29
    acetylacetone 0.2
    n-hexadecane 0.01
    acetophenone 0.15
    methyl propionate 0.24
    isopentyl acetate 0.11
    trichloroethylene 0.07
    n-nonanol 0.17
    cyclohexanol 0.38
    benzyl alcohol 0.15
    2-ethylhexanol 0.13
    isooctanol 0.18
    dipropyl ether 0.24
    1,2-dichlorobenzene 0.02
    ethyl lactate 0.56
    propylene carbonate 0.49
    n-methylformamide 3.27
    2-pentanol 0.17
    n-pentane 0.02
    1-propoxy-2-propanol 1.26
    1-methoxy-2-propyl acetate 0.34
    2-(2-methoxypropoxy) propanol 1.14
    mesitylene 0.02
    ε-caprolactone 0.68
    p-cymene 0.06
    epichlorohydrin 0.41
    1,1,1-trichloroethane 0.02
    2-aminoethanol 2.59
    morpholine-4-carbaldehyde 8.34
    sulfolane 7.42
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.34
    n-hexyl acetate 0.11
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 1.53
    sec-butyl acetate 0.04
    tert-butyl acetate 0.07
    decalin 0.01
    glycerin 18.14
    diglyme 2.61
    acrylic acid 1.83
    isopropyl myristate 0.06
    n-butyric acid 0.45
    acetyl acetate 0.06
    di(2-ethylhexyl) phthalate 0.13
    ethyl propionate 0.1
    nitromethane 3.37
    1,2-diethoxyethane 0.19
    benzonitrile 0.12
    trioctyl phosphate 0.13
    1-bromopropane 0.03
    gamma-valerolactone 3.25
    n-decanol 0.13
    triethyl phosphate 0.23
    4-methyl-2-pentanol 0.07
    propionitrile 0.16
    vinylene carbonate 0.42
    1,1,2-trichlorotrifluoroethane 3.65
    DMS 0.15
    cumene 0.02
    2-octanol 0.16
    2-hexanone 0.1
    octyl acetate 0.1
    limonene 0.09
    1,2-dimethoxyethane 1.2
    ethyl orthosilicate 0.2
    tributyl phosphate 0.11
    diacetone alcohol 0.59
    N,N-dimethylaniline 0.08
    acrylonitrile 0.34
    aniline 0.15
    1,3-propanediol 2.17
    bromobenzene 0.01
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.1
    2-methyl-cyclohexyl acetate 0.14
    tetrabutyl urea 0.37
    diisobutyl methanol 0.08
    2-phenylethanol 0.2
    styrene 0.02
    dioctyl adipate 0.09
    dimethyl sulfate 1.59
    ethyl butyrate 0.17
    methyl lactate 1.96
    butyl lactate 0.59
    diethyl carbonate 0.14
    propanediol butyl ether 1.57
    triethyl orthoformate 0.26
    p-tert-butyltoluene 0.05
    methyl 4-tert-butylbenzoate 0.39
    morpholine 0.8
    tert-butylamine 0.08
    n-dodecanol 0.09
    dimethoxymethane 1.13
    ethylene carbonate 0.28
    cyrene 2.73
    2-ethoxyethyl acetate 0.24
    2-ethylhexyl acetate 0.1
    1,2,4-trichlorobenzene 0.05
    4-methylpyridine 0.21
    dibutyl ether 0.09
    2,6-dimethyl-4-heptanol 0.08
    DEF 0.83
    dimethyl isosorbide 1.53
    tetrachloroethylene 0.1
    eugenol 0.67
    triacetin 0.25
    span 80 0.83
    1,4-butanediol 0.93
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.09
    methyl formate 1.74
    2-methyl-1-butanol 0.22
    n-decane 0.02
    butyronitrile 0.11
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.04
    1-chlorotetradecane 0.02
    n-nonane 0.02
    undecane 0.02
    tert-butylcyclohexane 0.0
    cyclooctane 0.02
    cyclopentanol 0.68
    tetrahydropyran 0.22
    tert-amyl methyl ether 0.11
    2,5,8-trioxanonane 2.01
    1-hexene 0.02
    2-isopropoxyethanol 0.58
    2,2,2-trifluoroethanol 3.23
    methyl butyrate 0.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction