Acetylcysteine Sodium

Overview IFRA Request a quote

  • Identifiers

    CAS number
    19542-74-6

    Molecular formula
    C5H8NNaO3S

    SMILES
    CC(=O)N[C@@H](CS)C(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 58.39%
    Meaty 49.82%
    Savory 45.84%
    Sulfurous 28.16%
    Cooked 27.45%
    Roasted 26.99%
    Sweet 25.34%
    Beefy 19.37%
    Burnt 18.77%
    Cooling 17.1%

     

    Flavor
    Odorless 58.67%
    Mild 29.92%
    Bland 25.39%
    Very mild 25.29%
    Cooked 24.9%
    Roasted 23.3%
    Yeast 21.63%
    Sweet-like 21.46%
    Sulfury 20.83%
    Taco 19.67%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    6.07 (neutral)

    Molecular weight
    185.18 g/mol

    Flash point

    • 151.7 ˚C est.

  • Synonyms

    • Acetylcysteine sodium
    • L-CYSTEINE, N-ACETYL-, SODIUM SALT
    • NRD80R06FB
    • Acetylcysteine sodium salt
    • CINNAMIDOPROPYLTRIMONIUM ACETYLCYSTEINATE
    • RefChem:109130
    • 243-143-6
    • Sodium N-acetyl-L-cysteinate
    • 19542-74-6
    • sodium;(2R)-2-acetamido-3-sulfanylpropanoate
    • sodium N-acetylcysteinate
    • UNII-NRD80R06FB
    • Acetylcysteine GNR
    • EINECS 243-143-6
    • Sodium N-Acetyl-Cysteinate
    • 63664-54-0
    • SODIUM ACETYL CYSTEINATE
    • SCHEMBL2505571
    • n-acetyl-l-cysteine sodium salt
    • ACETYLCYSTEINE SODIUM [MART.]
    • ACETYLCYSTEINE SODIUM [WHO-DD]
    • NS00082704
    • D07554
    • Q27285019
    • 19542-74-6

  • Applications

    Acetylcysteine Sodium (CAS 19542-74-6) is used as a chemical intermediate and reducing agent in pharmaceutical manufacturing and in the synthesis of sulfur-containing compounds; used as a stabilizer/antioxidant in plastic materials and coating formulations; investigated or used as an antioxidant additive in cosmetics and personal care; serves as a building block for cysteine-derived derivatives in chemical synthesis; may be employed in cleaning formulations as a reducing agent or antioxidant.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 109.97
    methanol 224.79
    isopropanol 58.12
    water 165.42
    ethyl acetate 23.62
    n-propanol 61.33
    acetone 119.31
    n-butanol 45.02
    acetonitrile 55.79
    DMF 649.64
    toluene 4.38
    isobutanol 34.86
    1,4-dioxane 76.71
    methyl acetate 38.61
    THF 78.89
    2-butanone 52.22
    n-pentanol 33.05
    sec-butanol 42.2
    n-hexane 1.52
    ethylene glycol 137.52
    NMP 240.58
    cyclohexane 0.87
    DMSO 658.2
    n-butyl acetate 15.23
    n-octanol 17.5
    chloroform 9.96
    n-propyl acetate 15.07
    acetic acid 73.94
    dichloromethane 22.07
    cyclohexanone 50.87
    propylene glycol 74.78
    isopropyl acetate 13.33
    DMAc 411.45
    2-ethoxyethanol 121.15
    isopentanol 32.73
    n-heptane 1.06
    ethyl formate 73.08
    1,2-dichloroethane 28.01
    n-hexanol 22.27
    2-methoxyethanol 245.61
    isobutyl acetate 7.56
    tetrachloromethane 3.37
    n-pentyl acetate 12.16
    transcutol 97.67
    n-heptanol 14.44
    ethylbenzene 5.3
    MIBK 21.23
    2-propoxyethanol 72.92
    tert-butanol 55.76
    MTBE 21.48
    2-butoxyethanol 41.78
    propionic acid 38.85
    o-xylene 7.64
    formic acid 189.14
    diethyl ether 21.38
    m-xylene 5.45
    p-xylene 6.59
    chlorobenzene 6.68
    dimethyl carbonate 25.81
    n-octane 0.91
    formamide 197.24
    cyclopentanone 78.1
    2-pentanone 37.67
    anisole 21.23
    cyclopentyl methyl ether 20.33
    gamma-butyrolactone 84.39
    1-methoxy-2-propanol 114.39
    pyridine 29.87
    3-pentanone 26.36
    furfural 124.21
    n-dodecane 1.07
    diethylene glycol 124.57
    diisopropyl ether 4.48
    tert-amyl alcohol 40.87
    acetylacetone 51.55
    n-hexadecane 1.15
    acetophenone 28.15
    methyl propionate 29.99
    isopentyl acetate 13.3
    trichloroethylene 27.72
    n-nonanol 15.84
    cyclohexanol 21.15
    benzyl alcohol 30.9
    2-ethylhexanol 11.06
    isooctanol 10.77
    dipropyl ether 9.33
    1,2-dichlorobenzene 9.35
    ethyl lactate 23.52
    propylene carbonate 36.62
    n-methylformamide 207.94
    2-pentanol 21.14
    n-pentane 1.49
    1-propoxy-2-propanol 36.73
    1-methoxy-2-propyl acetate 23.32
    2-(2-methoxypropoxy) propanol 47.41
    mesitylene 4.22
    ε-caprolactone 41.97
    p-cymene 5.21
    epichlorohydrin 76.07
    1,1,1-trichloroethane 8.74
    2-aminoethanol 125.26
    morpholine-4-carbaldehyde 216.83
    sulfolane 147.99
    2,2,4-trimethylpentane 0.9
    2-methyltetrahydrofuran 33.96
    n-hexyl acetate 17.44
    isooctane 0.61
    2-(2-butoxyethoxy)ethanol 57.0
    sec-butyl acetate 8.7
    tert-butyl acetate 15.59
    decalin 1.12
    glycerin 147.7
    diglyme 99.9
    acrylic acid 45.84
    isopropyl myristate 8.89
    n-butyric acid 37.21
    acetyl acetate 15.53
    di(2-ethylhexyl) phthalate 14.46
    ethyl propionate 16.17
    nitromethane 162.05
    1,2-diethoxyethane 23.31
    benzonitrile 23.11
    trioctyl phosphate 11.49
    1-bromopropane 10.98
    gamma-valerolactone 127.8
    n-decanol 12.89
    triethyl phosphate 11.86
    4-methyl-2-pentanol 11.89
    propionitrile 28.35
    vinylene carbonate 39.7
    1,1,2-trichlorotrifluoroethane 84.46
    DMS 17.27
    cumene 5.08
    2-octanol 10.36
    2-hexanone 22.34
    octyl acetate 12.43
    limonene 6.42
    1,2-dimethoxyethane 165.59
    ethyl orthosilicate 10.25
    tributyl phosphate 12.24
    diacetone alcohol 42.63
    N,N-dimethylaniline 24.74
    acrylonitrile 50.08
    aniline 15.59
    1,3-propanediol 115.26
    bromobenzene 4.51
    dibromomethane 11.83
    1,1,2,2-tetrachloroethane 24.78
    2-methyl-cyclohexyl acetate 13.13
    tetrabutyl urea 23.17
    diisobutyl methanol 7.33
    2-phenylethanol 22.13
    styrene 5.49
    dioctyl adipate 14.82
    dimethyl sulfate 70.69
    ethyl butyrate 13.45
    methyl lactate 47.49
    butyl lactate 19.53
    diethyl carbonate 10.77
    propanediol butyl ether 45.12
    triethyl orthoformate 10.98
    p-tert-butyltoluene 4.91
    methyl 4-tert-butylbenzoate 28.21
    morpholine 83.12
    tert-butylamine 23.29
    n-dodecanol 10.21
    dimethoxymethane 147.79
    ethylene carbonate 30.82
    cyrene 53.86
    2-ethoxyethyl acetate 19.27
    2-ethylhexyl acetate 9.8
    1,2,4-trichlorobenzene 11.57
    4-methylpyridine 35.9
    dibutyl ether 10.21
    2,6-dimethyl-4-heptanol 7.33
    DEF 82.54
    dimethyl isosorbide 55.83
    tetrachloroethylene 18.14
    eugenol 38.49
    triacetin 21.52
    span 80 30.28
    1,4-butanediol 63.6
    1,1-dichloroethane 12.25
    2-methyl-1-pentanol 25.25
    methyl formate 176.67
    2-methyl-1-butanol 31.16
    n-decane 1.53
    butyronitrile 30.84
    3,7-dimethyl-1-octanol 13.95
    1-chlorooctane 5.59
    1-chlorotetradecane 2.95
    n-nonane 1.38
    undecane 1.26
    tert-butylcyclohexane 1.11
    cyclooctane 0.53
    cyclopentanol 30.47
    tetrahydropyran 23.39
    tert-amyl methyl ether 19.21
    2,5,8-trioxanonane 80.95
    1-hexene 5.39
    2-isopropoxyethanol 54.52
    2,2,2-trifluoroethanol 52.74
    methyl butyrate 27.63

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction