Acetopiperone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    3162-29-6

    Molecular formula
    C9H8O3

    SMILES
    CC(=O)C1=CC2=C(C=C1)OCO2

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 88.33%
    Floral 85.62%
    Vanilla 67.36%
    Powdery 66.19%
    Coumarinic 49.61%
    Creamy 48.91%
    Hay 46.77%
    Balsamic 46.5%
    Hawthorn 46.25%
    Cherry 40.05%

     

    Flavor
    Sweet 91.2%
    Vanilla 56.94%
    Bitter 55.16%
    Woody 52.15%
    Powdery 49.71%
    Hawthorn 47.14%
    Creamy 36.97%
    Tonka 36.75%
    Floral 35.45%
    Coconut 34.83%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    7.08 (neutral)

    Molecular weight
    164.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    260°C

    Flash point

    • 135.4 ˚C est.

  • Synonyms

    • 3162-29-6
    • 3',4'-(Methylenedioxy)acetophenone
    • 1-(Benzo[d][1,3]dioxol-5-yl)ethanone
    • 5-Acetyl-1,3-benzodioxole
    • 1-(1,3-Benzodioxol-5-yl)ethanone
    • 3,4-Methylenedioxyacetophenone
    • Acetopiperone
    • 3',4'-Methylenedioxyacetophenone
    • 3,4-(Methylenedioxy)acetophenone
    • 1-(1,3-Benzodioxol-5-yl)ethan-1-one
    • Ethanone, 1-(1,3-benzodioxol-5-yl)-
    • MFCD00005831
    • 8JG2OH2M57
    • MOSKACHAN A
    • EINECS 221-613-1
    • 3,4-METHYLENDIOXYACETOPHENONE
    • NSC 21866
    • NSC-21866
    • AI3-30572
    • 1-(2H-1,3-benzodioxol-5-yl)ethan-1-one
    • 3,4-Methylenedioxy-acetophenone
    • BMHMKWXYXFBWMI-UHFFFAOYSA-
    • DTXSID40185502
    • 1-(BENZODIOXOL-5-YL)ETHANONE
    • 1-acetyl-3,4-(methylenedioxy)benzene
    • 1-(2H-1,3-benzodioxol-5-yl)ethanone
    • ACETOPHENONE, 3,4-METHYLENEDIOXY-
    • 1-(BENZ(D)(1,3)DIOXOL-5-YL)ETHANONE
    • ACETOPHENONE, 3',4'-(METHYLENEDIOXY)-
    • 3,4-(METHYLENEDIOXY)PHENYL METHYL KETONE
    • Acetopiperon
    • 4-ACETYLMETHYLENEDIOXYBENZENE
    • NSC21866
    • 1-Benzo[1,3]dioxol-5-yl-ethanone
    • UNII-8JG2OH2M57
    • 3,4-Methylenedioxycetophenone
    • 5 -acetyl-1,3-benzodioxole
    • MLS000515804
    • SCHEMBL137979
    • 3,4-Methylen-dioxy-acetophenon
    • 3,4-methylenedioxy acetophenone
    • CHEMBL1380211
    • DTXCID10107993
    • CHEBI:167425
    • 3', 4'-methylenedioxyacetophenone
    • 3',4'-methylenedioxy-acetophenone
    • HMS2268E15
    • 1-acetyl-3,4-methylenedioxybenzene
    • STR03337
    • STL183268
    • 1-(1,3-benzodioxol-5-yl)-ethanone
    • 3,4-METHYLENDIOXY ACETOPHENONE
    • AKOS000119406
    • AC-9517
    • CS-W010839
    • FM47148
    • FS-3660
    • SDCCGSBI-0660091.P001
    • 1-(1,3-benzodioxol-5-yl)acetaldehyde
    • 1-(1,3-Benzodioxol-5-yl)ethanone #
    • 1-(1,3-dioxaindan-5-yl)ethan-1-one
    • NCGC00246999-01
    • SMR000112277
    • SY048504
    • 3',4'-(Methylenedioxy)acetophenone, 98%
    • DB-048082
    • M0874
    • NS00029153
    • 1-(benzo[d][1,3]dioxol-5-yl)ethan-1-one
    • EN300-20343
    • F10428
    • AE-508/40226031
    • F0001-0949
    • 3 inverted exclamation mark ,4 inverted exclamation mark -(Methylenedioxy)acetophenone
    • 3 inverted exclamation marka,4 inverted exclamation marka-(Methylenedioxy)acetophenone
    • 221-613-1

  • Applications

    Acetopiperone (CAS 3162-29-6) is used as an organic intermediate and odor-related ingredient across several industrial sectors. In perfumery and fragrances, it may act as an odorant or fragrance precursor incorporated into formulations. In cosmetics and personal care, it may be evaluated as a fragrance component or processing aid in controlled formulations. In industrial manufacturing, it serves as a building block for organic synthesis and as a precursor to more complex compounds. In polymers and plastics, it is used as a precursor for resin or polymer production. In coatings and inks, it may function as a specialty intermediate for formulation development. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 72.26
    methanol 132.85
    isopropanol 51.79
    water 11.0
    ethyl acetate 147.76
    n-propanol 50.31
    acetone 232.29
    n-butanol 38.86
    acetonitrile 330.04
    DMF 390.47
    toluene 66.18
    isobutanol 39.35
    1,4-dioxane 396.25
    methyl acetate 232.85
    THF 222.81
    2-butanone 138.52
    n-pentanol 34.62
    sec-butanol 40.99
    n-hexane 2.45
    ethylene glycol 61.74
    NMP 260.25
    cyclohexane 9.08
    DMSO 301.37
    n-butyl acetate 44.47
    n-octanol 36.2
    chloroform 209.06
    n-propyl acetate 78.83
    acetic acid 155.79
    dichloromethane 343.54
    cyclohexanone 158.01
    propylene glycol 33.2
    isopropyl acetate 65.89
    DMAc 384.54
    2-ethoxyethanol 128.33
    isopentanol 39.31
    n-heptane 5.31
    ethyl formate 135.12
    1,2-dichloroethane 173.47
    n-hexanol 28.9
    2-methoxyethanol 201.53
    isobutyl acetate 39.4
    tetrachloromethane 28.93
    n-pentyl acetate 38.21
    transcutol 306.42
    n-heptanol 25.88
    ethylbenzene 37.14
    MIBK 53.92
    2-propoxyethanol 88.57
    tert-butanol 84.38
    MTBE 52.5
    2-butoxyethanol 66.15
    propionic acid 85.97
    o-xylene 55.14
    formic acid 131.92
    diethyl ether 71.27
    m-xylene 42.39
    p-xylene 59.66
    chlorobenzene 95.4
    dimethyl carbonate 115.58
    n-octane 3.87
    formamide 343.98
    cyclopentanone 193.36
    2-pentanone 79.88
    anisole 122.81
    cyclopentyl methyl ether 81.47
    gamma-butyrolactone 283.6
    1-methoxy-2-propanol 100.85
    pyridine 268.07
    3-pentanone 82.98
    furfural 289.02
    n-dodecane 5.26
    diethylene glycol 118.56
    diisopropyl ether 20.72
    tert-amyl alcohol 54.26
    acetylacetone 145.33
    n-hexadecane 5.88
    acetophenone 121.86
    methyl propionate 126.34
    isopentyl acetate 42.93
    trichloroethylene 310.69
    n-nonanol 35.89
    cyclohexanol 50.06
    benzyl alcohol 93.88
    2-ethylhexanol 24.66
    isooctanol 23.7
    dipropyl ether 35.99
    1,2-dichlorobenzene 95.88
    ethyl lactate 45.1
    propylene carbonate 128.59
    n-methylformamide 244.51
    2-pentanol 26.87
    n-pentane 3.14
    1-propoxy-2-propanol 49.74
    1-methoxy-2-propyl acetate 71.61
    2-(2-methoxypropoxy) propanol 88.08
    mesitylene 26.24
    ε-caprolactone 133.08
    p-cymene 24.29
    epichlorohydrin 308.13
    1,1,1-trichloroethane 118.29
    2-aminoethanol 63.8
    morpholine-4-carbaldehyde 359.25
    sulfolane 219.09
    2,2,4-trimethylpentane 2.7
    2-methyltetrahydrofuran 136.47
    n-hexyl acetate 60.93
    isooctane 2.0
    2-(2-butoxyethoxy)ethanol 107.78
    sec-butyl acetate 46.54
    tert-butyl acetate 64.87
    decalin 5.88
    glycerin 72.17
    diglyme 255.82
    acrylic acid 100.65
    isopropyl myristate 34.1
    n-butyric acid 72.73
    acetyl acetate 125.45
    di(2-ethylhexyl) phthalate 36.56
    ethyl propionate 74.66
    nitromethane 528.05
    1,2-diethoxyethane 97.45
    benzonitrile 132.79
    trioctyl phosphate 25.14
    1-bromopropane 52.63
    gamma-valerolactone 272.5
    n-decanol 29.62
    triethyl phosphate 40.66
    4-methyl-2-pentanol 20.82
    propionitrile 139.34
    vinylene carbonate 154.78
    1,1,2-trichlorotrifluoroethane 149.32
    DMS 81.93
    cumene 25.66
    2-octanol 19.57
    2-hexanone 61.95
    octyl acetate 40.54
    limonene 27.57
    1,2-dimethoxyethane 272.82
    ethyl orthosilicate 36.23
    tributyl phosphate 32.01
    diacetone alcohol 76.76
    N,N-dimethylaniline 84.81
    acrylonitrile 236.51
    aniline 96.31
    1,3-propanediol 79.53
    bromobenzene 93.06
    dibromomethane 143.41
    1,1,2,2-tetrachloroethane 176.66
    2-methyl-cyclohexyl acetate 48.63
    tetrabutyl urea 49.38
    diisobutyl methanol 20.35
    2-phenylethanol 63.05
    styrene 52.46
    dioctyl adipate 52.55
    dimethyl sulfate 157.26
    ethyl butyrate 57.33
    methyl lactate 65.01
    butyl lactate 31.86
    diethyl carbonate 55.36
    propanediol butyl ether 54.42
    triethyl orthoformate 44.12
    p-tert-butyltoluene 21.25
    methyl 4-tert-butylbenzoate 74.9
    morpholine 279.41
    tert-butylamine 42.55
    n-dodecanol 24.89
    dimethoxymethane 246.3
    ethylene carbonate 125.76
    cyrene 98.06
    2-ethoxyethyl acetate 73.35
    2-ethylhexyl acetate 34.05
    1,2,4-trichlorobenzene 106.56
    4-methylpyridine 204.46
    dibutyl ether 43.11
    2,6-dimethyl-4-heptanol 20.35
    DEF 139.27
    dimethyl isosorbide 147.8
    tetrachloroethylene 123.34
    eugenol 81.13
    triacetin 90.54
    span 80 56.08
    1,4-butanediol 41.34
    1,1-dichloroethane 130.14
    2-methyl-1-pentanol 35.22
    methyl formate 245.47
    2-methyl-1-butanol 34.4
    n-decane 7.33
    butyronitrile 90.86
    3,7-dimethyl-1-octanol 35.75
    1-chlorooctane 24.49
    1-chlorotetradecane 13.74
    n-nonane 6.23
    undecane 6.06
    tert-butylcyclohexane 4.61
    cyclooctane 3.75
    cyclopentanol 62.73
    tetrahydropyran 130.33
    tert-amyl methyl ether 41.57
    2,5,8-trioxanonane 195.62
    1-hexene 11.06
    2-isopropoxyethanol 81.75
    2,2,2-trifluoroethanol 104.86
    methyl butyrate 94.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction