Acetone, oxime

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  • Identifiers

    CAS number
    127-06-0

    Molecular formula
    C3H7NO

    SMILES
    CC(=NO)C

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Ethereal 43.39%
    Green 41.0%
    Pungent 40.45%
    Fermented 35.7%
    Alcoholic 32.96%
    Fruity 31.75%
    Fresh 29.71%
    Musty 29.17%
    Nutty 28.86%
    Vegetable 28.78%

     

    Flavor
    Pungent 40.68%
    Ethereal 32.13%
    Green 31.94%
    Vegetable 29.58%
    Fruity 28.7%
    Nutty 28.04%
    Mustard 27.32%
    Oily 26.76%
    Fishy 25.98%
    Musty 25.12%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.1

    pKa est.
    8.5 (weak base)

    Molecular weight
    73.09 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • 61 °C

    Boiling point

    • 133 °C
    • Boiling point = 134.8 °C at 728 mm Hg

    Flash point

    • 33.05 ˚C est.

    Solubility expt.

    • In water, 30.0 to 32.7% w/w at 20.0 °C
    • Soluble in water
    • Soluble in ethanol, diethyl ether, chloroform, ligroin

  • Synonyms

    • Acetone oxime
    • 127-06-0
    • Acetoxime
    • 2-Propanone, oxime
    • Acetonoxime
    • 2-Propanone oxime
    • Acetone, oxime
    • beta-Isonitrosopropane
    • QX74TFD64T
    • DTXSID6020010
    • NSC-7601
    • CHEBI:15349
    • actone oxime
    • RefChem:914970
    • DTXCID1010
    • 204-820-1
    • propan-2-one oxime
    • N-propan-2-ylidenehydroxylamine
    • propanone oxime
    • .beta.-Isonitrosopropane
    • propan-2-oneoxime
    • MFCD00002118
    • N-(propan-2-ylidene)hydroxylamine
    • Propan-2-one oxime(Chunks or pellets)
    • propane, 2-hydroxyimino-
    • CCRIS 5
    • NSC 7601
    • EINECS 204-820-1
    • UNII-QX74TFD64T
    • N-isopropylidenehydroxylamine
    • BRN 1560146
    • dimethylnitrone
    • AI3-52259
    • Propane-2-one oxime
    • ACETONE-OXIME
    • Acetone oxime, 98%
    • ACETONE OXIME,
    • ACETOXIME [MI]
    • N-hydroxypropan-2-imine
    • EC 204-820-1
    • SCHEMBL2206
    • N-isopropylidene-hydroxylamine
    • 4-01-00-03202 (Beilstein Handbook Reference)
    • (CH3)2C=NOH
    • orb2939779
    • SCHEMBL1527278
    • SCHEMBL3579406
    • SCHEMBL4192140
    • SCHEMBL4192141
    • SCHEMBL8054304
    • WLN: QNUY1 & 1
    • SCHEMBL10650171
    • SCHEMBL10650179
    • HSDB 8484
    • NSC7601
    • STL185580
    • AKOS005068118
    • CS-W009556
    • HY-W008840
    • Acetone oxime, purum, >=98.0% (GC)
    • DB-062562
    • A0065
    • NS00010056
    • EN300-31960
    • Acetone oxime, Vetec(TM) reagent grade, 98%
    • C01995
    • D70154
    • A805635
    • F100400
    • InChI=1/C3H7NO/c1-3(2)4-5/h5H,1-2H
    • Q16744025
    • F0001-0388
    • 2-Propanone oxime; Acetoxime; Dimethyl Ketoxime; Exkin 518; N-Isopropylidenehydroxylamine; beta-Isonitrosopropane
    • 127-06-0

  • Applications

    Acetone oxime, CAS 127-06-0, is a polar solvent and processing aid used widely in industrial formulations and serves as an intermediate for oxime derivatives in organic synthesis. In coatings and inks, it acts as a solvent and dissolving medium; in plastics, polymers, and adhesives it can function as a processing solvent or co-solvent to improve mixing and formulation stability. It is also used as a chemical intermediate to access oxime-containing building blocks and specialty oxime derivatives. Its use should be carried out in accordance with local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 220.72
    methanol 374.75
    isopropanol 140.68
    water 167.6
    ethyl acetate 38.34
    n-propanol 138.67
    acetone 99.34
    n-butanol 119.22
    acetonitrile 108.97
    DMF 168.25
    toluene 12.09
    isobutanol 103.36
    1,4-dioxane 60.98
    methyl acetate 65.69
    THF 97.82
    2-butanone 74.77
    n-pentanol 74.35
    sec-butanol 116.86
    n-hexane 9.85
    ethylene glycol 88.6
    NMP 154.21
    cyclohexane 4.55
    DMSO 116.05
    n-butyl acetate 24.84
    n-octanol 39.64
    chloroform 145.39
    n-propyl acetate 24.67
    acetic acid 245.74
    dichloromethane 108.38
    cyclohexanone 69.04
    propylene glycol 103.59
    isopropyl acetate 22.94
    DMAc 154.8
    2-ethoxyethanol 92.5
    isopentanol 86.22
    n-heptane 6.52
    ethyl formate 61.51
    1,2-dichloroethane 47.32
    n-hexanol 57.76
    2-methoxyethanol 179.58
    isobutyl acetate 16.77
    tetrachloromethane 39.57
    n-pentyl acetate 30.71
    transcutol 153.64
    n-heptanol 44.99
    ethylbenzene 10.53
    MIBK 28.01
    2-propoxyethanol 80.65
    tert-butanol 122.93
    MTBE 47.85
    2-butoxyethanol 78.5
    propionic acid 131.92
    o-xylene 15.02
    formic acid 237.6
    diethyl ether 36.99
    m-xylene 11.34
    p-xylene 18.26
    chlorobenzene 23.04
    dimethyl carbonate 18.56
    n-octane 3.76
    formamide 218.74
    cyclopentanone 102.35
    2-pentanone 45.31
    anisole 26.73
    cyclopentyl methyl ether 40.26
    gamma-butyrolactone 115.67
    1-methoxy-2-propanol 116.2
    pyridine 60.41
    3-pentanone 34.7
    furfural 116.91
    n-dodecane 2.7
    diethylene glycol 73.56
    diisopropyl ether 10.59
    tert-amyl alcohol 112.24
    acetylacetone 37.42
    n-hexadecane 2.73
    acetophenone 32.43
    methyl propionate 42.3
    isopentyl acetate 25.8
    trichloroethylene 94.54
    n-nonanol 34.26
    cyclohexanol 56.35
    benzyl alcohol 40.45
    2-ethylhexanol 31.68
    isooctanol 34.29
    dipropyl ether 19.6
    1,2-dichlorobenzene 23.61
    ethyl lactate 25.54
    propylene carbonate 61.01
    n-methylformamide 147.78
    2-pentanol 71.04
    n-pentane 9.84
    1-propoxy-2-propanol 56.37
    1-methoxy-2-propyl acetate 24.91
    2-(2-methoxypropoxy) propanol 53.64
    mesitylene 7.73
    ε-caprolactone 66.77
    p-cymene 10.51
    epichlorohydrin 88.0
    1,1,1-trichloroethane 51.77
    2-aminoethanol 149.43
    morpholine-4-carbaldehyde 113.47
    sulfolane 117.93
    2,2,4-trimethylpentane 7.47
    2-methyltetrahydrofuran 74.91
    n-hexyl acetate 41.21
    isooctane 3.7
    2-(2-butoxyethoxy)ethanol 72.92
    sec-butyl acetate 16.72
    tert-butyl acetate 23.61
    decalin 4.59
    glycerin 121.96
    diglyme 101.1
    acrylic acid 127.82
    isopropyl myristate 14.93
    n-butyric acid 113.97
    acetyl acetate 25.24
    di(2-ethylhexyl) phthalate 22.35
    ethyl propionate 21.68
    nitromethane 207.58
    1,2-diethoxyethane 33.59
    benzonitrile 41.01
    trioctyl phosphate 15.64
    1-bromopropane 34.14
    gamma-valerolactone 121.64
    n-decanol 23.07
    triethyl phosphate 14.95
    4-methyl-2-pentanol 36.7
    propionitrile 67.49
    vinylene carbonate 56.26
    1,1,2-trichlorotrifluoroethane 115.93
    DMS 25.32
    cumene 11.11
    2-octanol 30.59
    2-hexanone 33.0
    octyl acetate 21.63
    limonene 14.42
    1,2-dimethoxyethane 82.29
    ethyl orthosilicate 15.02
    tributyl phosphate 18.01
    diacetone alcohol 54.4
    N,N-dimethylaniline 27.43
    acrylonitrile 83.6
    aniline 39.36
    1,3-propanediol 148.81
    bromobenzene 15.9
    dibromomethane 70.91
    1,1,2,2-tetrachloroethane 81.83
    2-methyl-cyclohexyl acetate 23.58
    tetrabutyl urea 23.64
    diisobutyl methanol 17.16
    2-phenylethanol 32.61
    styrene 11.66
    dioctyl adipate 23.82
    dimethyl sulfate 32.44
    ethyl butyrate 19.74
    methyl lactate 44.37
    butyl lactate 36.09
    diethyl carbonate 13.98
    propanediol butyl ether 80.93
    triethyl orthoformate 17.48
    p-tert-butyltoluene 10.31
    methyl 4-tert-butylbenzoate 39.79
    morpholine 90.43
    tert-butylamine 76.63
    n-dodecanol 16.0
    dimethoxymethane 56.53
    ethylene carbonate 40.29
    cyrene 50.75
    2-ethoxyethyl acetate 36.66
    2-ethylhexyl acetate 20.35
    1,2,4-trichlorobenzene 32.36
    4-methylpyridine 58.67
    dibutyl ether 23.84
    2,6-dimethyl-4-heptanol 17.16
    DEF 59.5
    dimethyl isosorbide 59.4
    tetrachloroethylene 69.16
    eugenol 44.3
    triacetin 37.96
    span 80 53.61
    1,4-butanediol 65.83
    1,1-dichloroethane 60.79
    2-methyl-1-pentanol 65.05
    methyl formate 92.73
    2-methyl-1-butanol 94.92
    n-decane 4.69
    butyronitrile 67.41
    3,7-dimethyl-1-octanol 33.49
    1-chlorooctane 16.02
    1-chlorotetradecane 5.88
    n-nonane 4.69
    undecane 3.4
    tert-butylcyclohexane 6.01
    cyclooctane 2.13
    cyclopentanol 85.24
    tetrahydropyran 50.04
    tert-amyl methyl ether 41.09
    2,5,8-trioxanonane 70.54
    1-hexene 24.52
    2-isopropoxyethanol 59.31
    2,2,2-trifluoroethanol 124.32
    methyl butyrate 33.99

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction