Acetic acid, C>19-alkyl esters

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  • Identifiers

    CAS number
    822-24-2

    Molecular formula
    C22H44O2

    SMILES
    CCCCCCCCCCCCCCCCCCCCOC(=O)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 75.6%
    Fatty 62.12%
    Oily 54.79%
    Sweet 34.55%
    Fruity 32.06%
    Odorless 25.59%
    Clean 25.51%
    Creamy 24.82%
    Dairy 20.92%
    Fresh 20.7%

     

    Flavor
    Waxy 68.89%
    Fatty 42.87%
    Mild 41.68%
    Oily 39.92%
    Soapy 36.29%
    Fat 33.06%
    Coconut 31.98%
    Alkane 31.26%
    Wax 30.48%
    Bland 27.68%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.9

    pKa est.
    7.92 (neutral)

    Molecular weight
    340.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    398°C

    Flash point

    • 181.11 ˚C est.

  • Synonyms

    • RefChem:11117
    • DTXCID801507176
    • DTXSID601022439
    • 270-816-1
    • icosyl acetate
    • Eicosyl acetate
    • 822-24-2
    • n-Eicosyl acetate
    • MFCD00056263
    • Acetic acid icosyl ester
    • Eicosanyl acetate
    • icosylacetate
    • EINECS 270-816-1
    • 1-Eicosanol acetate
    • SCHEMBL3220282
    • SCHEMBL8915954
    • SCHEMBL28609977
    • DTXSID00867635
    • CHEBI:196301
    • LMFA07010403
    • AKOS030525245
    • HY-W560875
    • AS-56523
    • NS00122670
    • A11803
    • 822-24-2

  • Applications

    Acetic acid, C>19-alkyl esters (CAS 822-24-2) are long-chain alkyl acetates used as high-boiling solvents and as plasticizers in a range of formulations. In cosmetics and personal care, they typically act as emollients and conditioning components for creams, lotions, and makeup products. In fragrance applications, these long-chain acetates can serve as fragrance carriers or fixatives, helping to modulate volatility and extend scent longevity. In the plastics and coatings industries, they are used as plasticizers or processing aids to improve flexibility and film formation in polymers, paints, and adhesives. In household cleaning formulations, they may appear as solvent components or conditioning agents, and in ink and coating formulations as carriers for active ingredients, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.02
    methanol 9.38
    isopropanol 11.47
    water 0.01
    ethyl acetate 133.69
    n-propanol 13.8
    acetone 59.51
    n-butanol 18.77
    acetonitrile 23.75
    DMF 121.31
    toluene 55.53
    isobutanol 18.57
    1,4-dioxane 143.57
    methyl acetate 75.52
    THF 427.23
    2-butanone 103.75
    n-pentanol 19.93
    sec-butanol 22.61
    n-hexane 19.21
    ethylene glycol 0.97
    NMP 483.6
    cyclohexane 115.94
    DMSO 156.34
    n-butyl acetate 204.35
    n-octanol 44.64
    chloroform 502.09
    n-propyl acetate 205.77
    acetic acid 30.51
    dichloromethane 514.24
    cyclohexanone 466.76
    propylene glycol 3.49
    isopropyl acetate 155.17
    DMAc 301.83
    2-ethoxyethanol 52.85
    isopentanol 34.7
    n-heptane 27.78
    ethyl formate 51.18
    1,2-dichloroethane 308.47
    n-hexanol 24.71
    2-methoxyethanol 43.83
    isobutyl acetate 149.2
    tetrachloromethane 130.73
    n-pentyl acetate 331.7
    transcutol 452.58
    n-heptanol 34.97
    ethylbenzene 57.08
    MIBK 153.22
    2-propoxyethanol 64.79
    tert-butanol 38.89
    MTBE 105.06
    2-butoxyethanol 101.68
    propionic acid 35.51
    o-xylene 65.62
    formic acid 5.28
    diethyl ether 66.28
    m-xylene 52.6
    p-xylene 90.55
    chlorobenzene 132.57
    dimethyl carbonate 31.89
    n-octane 14.13
    formamide 11.99
    cyclopentanone 438.1
    2-pentanone 126.22
    anisole 127.53
    cyclopentyl methyl ether 262.94
    gamma-butyrolactone 388.81
    1-methoxy-2-propanol 60.86
    pyridine 165.92
    3-pentanone 125.19
    furfural 274.85
    n-dodecane 7.26
    diethylene glycol 20.29
    diisopropyl ether 55.88
    tert-amyl alcohol 58.26
    acetylacetone 197.04
    n-hexadecane 9.39
    acetophenone 184.12
    methyl propionate 92.43
    isopentyl acetate 218.28
    trichloroethylene 550.0
    n-nonanol 49.48
    cyclohexanol 85.26
    benzyl alcohol 54.27
    2-ethylhexanol 48.92
    isooctanol 45.57
    dipropyl ether 151.25
    1,2-dichlorobenzene 210.15
    ethyl lactate 65.08
    propylene carbonate 240.36
    n-methylformamide 31.35
    2-pentanol 22.95
    n-pentane 9.9
    1-propoxy-2-propanol 98.17
    1-methoxy-2-propyl acetate 191.9
    2-(2-methoxypropoxy) propanol 133.83
    mesitylene 52.42
    ε-caprolactone 413.13
    p-cymene 61.8
    epichlorohydrin 409.02
    1,1,1-trichloroethane 418.35
    2-aminoethanol 4.61
    morpholine-4-carbaldehyde 280.63
    sulfolane 777.4
    2,2,4-trimethylpentane 16.73
    2-methyltetrahydrofuran 326.03
    n-hexyl acetate 283.06
    isooctane 9.51
    2-(2-butoxyethoxy)ethanol 158.28
    sec-butyl acetate 178.03
    tert-butyl acetate 261.59
    decalin 44.2
    glycerin 8.46
    diglyme 433.92
    acrylic acid 24.62
    isopropyl myristate 103.57
    n-butyric acid 91.61
    acetyl acetate 110.87
    di(2-ethylhexyl) phthalate 70.87
    ethyl propionate 182.77
    nitromethane 96.89
    1,2-diethoxyethane 249.65
    benzonitrile 88.64
    trioctyl phosphate 53.22
    1-bromopropane 165.84
    gamma-valerolactone 526.5
    n-decanol 30.96
    triethyl phosphate 152.4
    4-methyl-2-pentanol 25.95
    propionitrile 33.97
    vinylene carbonate 165.03
    1,1,2-trichlorotrifluoroethane 249.94
    DMS 134.84
    cumene 49.69
    2-octanol 41.38
    2-hexanone 162.57
    octyl acetate 114.23
    limonene 124.88
    1,2-dimethoxyethane 245.61
    ethyl orthosilicate 151.03
    tributyl phosphate 79.59
    diacetone alcohol 164.97
    N,N-dimethylaniline 103.96
    acrylonitrile 34.32
    aniline 51.46
    1,3-propanediol 10.88
    bromobenzene 178.22
    dibromomethane 312.11
    1,1,2,2-tetrachloroethane 617.58
    2-methyl-cyclohexyl acetate 238.82
    tetrabutyl urea 135.83
    diisobutyl methanol 51.94
    2-phenylethanol 55.13
    styrene 64.27
    dioctyl adipate 179.61
    dimethyl sulfate 106.87
    ethyl butyrate 257.0
    methyl lactate 37.98
    butyl lactate 157.72
    diethyl carbonate 137.63
    propanediol butyl ether 73.34
    triethyl orthoformate 231.12
    p-tert-butyltoluene 58.86
    methyl 4-tert-butylbenzoate 228.27
    morpholine 182.78
    tert-butylamine 32.41
    n-dodecanol 22.32
    dimethoxymethane 81.65
    ethylene carbonate 154.81
    cyrene 154.62
    2-ethoxyethyl acetate 282.78
    2-ethylhexyl acetate 210.14
    1,2,4-trichlorobenzene 246.75
    4-methylpyridine 171.53
    dibutyl ether 196.81
    2,6-dimethyl-4-heptanol 51.94
    DEF 207.57
    dimethyl isosorbide 386.5
    tetrachloroethylene 359.44
    eugenol 149.95
    triacetin 324.19
    span 80 128.55
    1,4-butanediol 5.88
    1,1-dichloroethane 233.46
    2-methyl-1-pentanol 35.96
    methyl formate 25.39
    2-methyl-1-butanol 31.18
    n-decane 18.73
    butyronitrile 45.77
    3,7-dimethyl-1-octanol 60.97
    1-chlorooctane 89.78
    1-chlorotetradecane 26.48
    n-nonane 18.5
    undecane 10.73
    tert-butylcyclohexane 30.35
    cyclooctane 29.04
    cyclopentanol 79.99
    tetrahydropyran 240.31
    tert-amyl methyl ether 126.84
    2,5,8-trioxanonane 251.94
    1-hexene 39.49
    2-isopropoxyethanol 59.55
    2,2,2-trifluoroethanol 21.44
    methyl butyrate 260.71

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction