Acetamiprid

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  • Identifiers

    CAS number
    135410-20-7

    Molecular formula
    C10H11ClN4

    SMILES
    CC(=NC#N)N(C)CC1=CN=C(C=C1)Cl

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Roasted 33.64%
    Meaty 28.88%
    Odorless 28.05%
    Nutty 27.29%
    Sweet 26.62%
    Burnt 22.85%
    Popcorn 22.8%
    Citrus 22.09%
    Animal 20.33%
    Cooked 20.05%

     

    Flavor
    Bitter 70.11%
    Odorless 30.84%
    Roasted 22.2%
    Bland 22.16%
    Nitrile 19.84%
    Taco 19.01%
    Roasted peanuts 18.98%
    Cedarleaf 18.95%
    Bread crust 18.85%
    Scallion 18.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    5.5 (weak acid)

    Molecular weight
    222.67 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    410°C

    Melting point expt.

    • 98.9 °C

    Flash point

    • 162.45 ˚C est.

    Solubility expt.

    • In water, 4.25X10+3 mg/L at 25 °C
    • In water at 25 °C: 3.48X10+3 mg/L at pH5; 2.95X10+3 mg/L at pH 7, 3.96X10+3 mg/L at pH 9
    • Soluble in acetone, methanol, ethanol, dichloromethane, chloroform, acetonitrile, and tetrahydrofuran

  • Synonyms

    • Acetamiprid
    • 135410-20-7
    • 160430-64-8
    • Intruder
    • Mospilan
    • Stonkat
    • Assail
    • Piorun
    • Prize
    • Acetamiprid [ISO]
    • N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide
    • NI 25
    • (E)-N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide
    • (E)-acetamiprid
    • Gazelle SG
    • Mospilan 20SP
    • NI-25
    • NFK 17
    • HSDB 7274
    • (Z)-acetamiprid
    • ADA 06200
    • Ethanimidamide, N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methyl-, (1E)-
    • TD 2472
    • TD 2480
    • TD-2472
    • TD-2480
    • PROFIL
    • CCRIS 9238
    • DTXSID0034300
    • CHEBI:39163
    • CHEBI:39164
    • TRI-STAR
    • 5HL5N372P0
    • Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-, (E)-
    • Ethanimidamide, N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methyl-,(1E)-
    • TD 2472-01
    • ACETAMIPRID [MI]
    • MFCD06201842
    • ACETAMIPRID [HSDB]
    • (E)-N-(6-Chloro-3-pyridyl)methyl-N'-cyano-N-methylacetamidine
    • N-((6-Chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide
    • BY 102960
    • NFK-17
    • DTXCID7032422
    • N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide
    • (1E)-N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide
    • ADA-06200
    • (E)-N(sup 1)-((6-chloro-3-pyridyl)methyl)-N(sup 2)-cyano-N(sup 1)-methylacetamidine
    • TD-2472-01
    • Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-
    • Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-, (1E)-
    • (1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide
    • (E)-N^1^-[(6-Chloropyridin-3-yl)methyl]-N^2^-cyano-N^1^-methylacetamidine
    • Acetamipride
    • UNII-5HL5N372P0
    • N-((6-chloropyridin-3-yl)methyl)-N'-cyano-N-methylethanimidamide
    • N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide
    • (E)-N-((6-chloropyridin-3-yl)methyl)-N'-cyano-N-methylethenimidamide
    • (E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethenimidamide
    • (E)-N^1^-((6-Chloropyridin-3-yl)methyl)-N^2^-cyano-N^1^-methylacetamidine
    • (E/Z)-Acetamiprid
    • Acetamiprid 10 microg/mL in Ethyl acetate
    • SCHEMBL26296
    • CHEMBL265941
    • CHEMBL3185634
    • SCHEMBL13448458
    • CHEBI:39165
    • N-(6-Chloro-3-pyridylmethyl)-N-cyano-N-methylacetamidine
    • DTXSID901015148
    • 66 - Neonicotinoids in groundwater
    • Tox21_301046
    • BDBM50486223
    • AKOS015891945
    • AKOS015964740
    • AKOS030228384
    • (1E)-N-
    • FA16947
    • USEPA/OPP Pesticide Code: 099050
    • NCGC00163881-01
    • NCGC00163881-02
    • NCGC00163881-03
    • NCGC00254948-01
    • AS-12113
    • SY317431
    • DB-042287
    • CAS-135410-20-7
    • CS-0166829
    • NS00000453
    • NS00117944
    • Acetamiprid, PESTANAL(R), analytical standard
    • C18507
    • EN300-6730808
    • EN300-6732053
    • Q421598
    • (E)N(6Chloro3pyridyl)methylN'cyanoNmethylacetamidine
    • Q27119764
    • (E)-N-(6-Chloro-3-pyridylmethyl)-N'-cyano-N-methylacetamidine
    • N-[(6-chloro-3-pyridyl)methyl]-N'-cyano-N-methyl-acetamidine
    • (e)-n1-[(6-chloro-3-pyridyl)methyl]-n2-cyano-n1-methylacetamidine
    • Ethanimidamide, N((6chloro3pyridinyl)methyl)N'cyanoNmethyl, (E)
    • (1Z)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide
    • (E)-N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide
    • (Z)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide
    • N-[(6-Chloro-3-pyridinyl)methyl]-Na(2)-cyano-N-methylethanimidamide
    • (1E)-N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide;ADA 06200;Assail
    • N-[(6-Chloro-3-pyridyl)methyl]-N inverted exclamation mark -cyano-N-methylacetimidamide

  • Applications

    Acetamiprid is a systemic neonicotinoid insecticide used in agriculture to protect crops from sap-sucking and chewing pests. It is commonly applied as foliar sprays and seed/soil treatments across crops such as fruits, vegetables, and ornamentals, including greenhouse and protected-culture settings. The product is often incorporated into integrated pest management (IPM) programs and may be formulated for consumer home-and-garden pest control products, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 100.76
    methanol 184.23
    isopropanol 31.74
    water 4.43
    ethyl acetate 52.64
    n-propanol 27.48
    acetone 688.77
    n-butanol 6.84
    acetonitrile 162.91
    DMF 1454.31
    toluene 26.92
    isobutanol 11.92
    1,4-dioxane 237.92
    methyl acetate 167.09
    THF 285.75
    2-butanone 224.15
    n-pentanol 11.17
    sec-butanol 13.07
    n-hexane 0.24
    ethylene glycol 74.1
    NMP 1092.59
    cyclohexane 0.61
    DMSO 2387.93
    n-butyl acetate 27.11
    n-octanol 3.76
    chloroform 331.45
    n-propyl acetate 38.74
    acetic acid 288.95
    dichloromethane 393.02
    cyclohexanone 158.9
    propylene glycol 54.73
    isopropyl acetate 23.39
    DMAc 1550.49
    2-ethoxyethanol 96.76
    isopentanol 6.27
    n-heptane 0.41
    ethyl formate 102.78
    1,2-dichloroethane 201.2
    n-hexanol 9.05
    2-methoxyethanol 195.84
    isobutyl acetate 22.23
    tetrachloromethane 21.84
    n-pentyl acetate 18.63
    transcutol 145.73
    n-heptanol 5.95
    ethylbenzene 6.94
    MIBK 19.37
    2-propoxyethanol 60.85
    tert-butanol 22.18
    MTBE 16.33
    2-butoxyethanol 32.42
    propionic acid 78.92
    o-xylene 14.34
    formic acid 312.21
    diethyl ether 13.65
    m-xylene 13.41
    p-xylene 16.71
    chlorobenzene 74.06
    dimethyl carbonate 90.42
    n-octane 0.19
    formamide 514.84
    cyclopentanone 379.19
    2-pentanone 52.07
    anisole 45.04
    cyclopentyl methyl ether 32.2
    gamma-butyrolactone 382.67
    1-methoxy-2-propanol 75.06
    pyridine 310.76
    3-pentanone 61.45
    furfural 482.03
    n-dodecane 0.21
    diethylene glycol 95.41
    diisopropyl ether 2.52
    tert-amyl alcohol 13.96
    acetylacetone 140.44
    n-hexadecane 0.26
    acetophenone 73.3
    methyl propionate 85.01
    isopentyl acetate 22.05
    trichloroethylene 616.27
    n-nonanol 3.95
    cyclohexanol 9.8
    benzyl alcohol 54.09
    2-ethylhexanol 5.38
    isooctanol 5.2
    dipropyl ether 7.1
    1,2-dichlorobenzene 64.99
    ethyl lactate 32.25
    propylene carbonate 128.37
    n-methylformamide 511.68
    2-pentanol 4.13
    n-pentane 0.22
    1-propoxy-2-propanol 31.19
    1-methoxy-2-propyl acetate 48.93
    2-(2-methoxypropoxy) propanol 39.43
    mesitylene 6.56
    ε-caprolactone 100.43
    p-cymene 5.98
    epichlorohydrin 446.9
    1,1,1-trichloroethane 123.58
    2-aminoethanol 71.35
    morpholine-4-carbaldehyde 527.93
    sulfolane 523.29
    2,2,4-trimethylpentane 0.29
    2-methyltetrahydrofuran 85.79
    n-hexyl acetate 17.03
    isooctane 0.18
    2-(2-butoxyethoxy)ethanol 44.37
    sec-butyl acetate 17.68
    tert-butyl acetate 22.63
    decalin 0.5
    glycerin 88.91
    diglyme 135.59
    acrylic acid 133.12
    isopropyl myristate 6.45
    n-butyric acid 44.1
    acetyl acetate 59.65
    di(2-ethylhexyl) phthalate 16.7
    ethyl propionate 26.58
    nitromethane 976.52
    1,2-diethoxyethane 32.07
    benzonitrile 84.08
    trioctyl phosphate 8.42
    1-bromopropane 24.72
    gamma-valerolactone 487.37
    n-decanol 3.08
    triethyl phosphate 17.41
    4-methyl-2-pentanol 3.21
    propionitrile 54.63
    vinylene carbonate 153.11
    1,1,2-trichlorotrifluoroethane 449.28
    DMS 59.26
    cumene 5.07
    2-octanol 3.23
    2-hexanone 42.79
    octyl acetate 10.1
    limonene 6.64
    1,2-dimethoxyethane 163.05
    ethyl orthosilicate 13.44
    tributyl phosphate 11.21
    diacetone alcohol 40.92
    N,N-dimethylaniline 28.91
    acrylonitrile 142.97
    aniline 63.59
    1,3-propanediol 50.26
    bromobenzene 69.91
    dibromomethane 144.23
    1,1,2,2-tetrachloroethane 363.62
    2-methyl-cyclohexyl acetate 21.15
    tetrabutyl urea 16.96
    diisobutyl methanol 3.59
    2-phenylethanol 34.84
    styrene 12.63
    dioctyl adipate 16.59
    dimethyl sulfate 267.49
    ethyl butyrate 20.66
    methyl lactate 73.92
    butyl lactate 22.35
    diethyl carbonate 19.76
    propanediol butyl ether 31.17
    triethyl orthoformate 16.47
    p-tert-butyltoluene 5.68
    methyl 4-tert-butylbenzoate 36.63
    morpholine 240.94
    tert-butylamine 6.9
    n-dodecanol 2.34
    dimethoxymethane 202.85
    ethylene carbonate 93.7
    cyrene 75.59
    2-ethoxyethyl acetate 51.99
    2-ethylhexyl acetate 16.56
    1,2,4-trichlorobenzene 117.1
    4-methylpyridine 213.44
    dibutyl ether 4.13
    2,6-dimethyl-4-heptanol 3.59
    DEF 119.25
    dimethyl isosorbide 77.62
    tetrachloroethylene 191.77
    eugenol 44.18
    triacetin 49.45
    span 80 27.18
    1,4-butanediol 30.53
    1,1-dichloroethane 136.84
    2-methyl-1-pentanol 8.46
    methyl formate 423.36
    2-methyl-1-butanol 6.25
    n-decane 0.29
    butyronitrile 27.58
    3,7-dimethyl-1-octanol 4.52
    1-chlorooctane 2.17
    1-chlorotetradecane 1.05
    n-nonane 0.23
    undecane 0.25
    tert-butylcyclohexane 0.48
    cyclooctane 0.19
    cyclopentanol 28.18
    tetrahydropyran 54.6
    tert-amyl methyl ether 10.47
    2,5,8-trioxanonane 82.44
    1-hexene 1.69
    2-isopropoxyethanol 48.05
    2,2,2-trifluoroethanol 168.86
    methyl butyrate 42.63

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction