Acetaldehyde ethyl isopropyl acetal, (+/-)-

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  • Identifiers

    CAS number
    25334-93-4

    Molecular formula
    C7H16O2

    SMILES
    CCOC(C)OC(C)C

  • Odor profile

    Fragrance
    Green 90.89%
    Ethereal 87.99%
    Alcoholic 76.17%
    Cognac 67.57%
    Fruity 66.42%
    Nutty 57.02%
    Fermented 53.48%
    Pungent 52.68%
    Vegetable 46.94%
    Malty 43.36%

     

    Flavor
    Green 54.54%
    Fruity 45.6%
    Vegetable 43.55%
    Earthy 38.78%
    Sweet 38.7%
    Ether 37.86%
    Ethereal 36.83%
    Fruit 34.21%
    Fatty 32.74%
    Tropical 30.3%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    8.29 (weak base)

    Molecular weight
    132.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    116°C

    Flash point

    • 7.34 ˚C est.

  • Synonyms

    • 2-(1-ethoxyethoxy)propane
    • Propane, 2-(1-ethoxyethoxy)-
    • 25334-93-4
    • P6I82WL83F
    • AI3-38087
    • acetaldehyde ethyl isopropyl acetal
    • Acetaldehyde ethyl isopropyl acetal, (+/-)-
    • FEMA NO. 4432
    • DTXSID30865205
    • 2-(1-ETHOXY)ETHOXYPROPANE
    • 1-ETHOXY-1-ISOPROPOXYETHANE
    • ETHANE, 1-ETHOXY-1-ISOPROPOXY-
    • Ethane, 1-ethoxy-1-(2-methylpropyloxy)
    • ACETALDEHYDE, ETHYL ISOPROPYL ACETAL
    • UNII-P6I82WL83F
    • SCHEMBL272528
    • DTXCID30813640
    • (+/-)-acetaldehyde ethyl isopropyl acetal
    • DB-288976
    • Q27286289
    • 607-701-6

  • Applications

    Acetaldehyde ethyl isopropyl acetal, (+/-)- is primarily used as an intermediate and protecting group for the aldehyde functionality in organic synthesis, notably in fine chemical and carbohydrate chemistry. It is also employed as a solvent or reaction medium in specialty chemical and pharmaceutical manufacturing, in the form of a co solvent or processing solvent, and can participate in the preparation of other acetals and ethers. In the polymer and coatings/inks sector, it can serve as a processing solvent, medium, or additive in plastic and resin formulations, helping to moderate reaction rates and volatility. As an acetal, it can provide a feedstock for the production of related acetals and derivatives in streamlined synthetic routes. Applications depend on local regulations and formulation constraints, so compliance with regulatory and formulation limits is essential.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1804.73
    methanol 2421.64
    isopropanol 1472.74
    water 22.15
    ethyl acetate 839.36
    n-propanol 1515.77
    acetone 889.08
    n-butanol 1330.01
    acetonitrile 1064.86
    DMF 897.18
    toluene 607.4
    isobutanol 1063.34
    1,4-dioxane 1758.7
    methyl acetate 781.83
    THF 2047.52
    2-butanone 745.28
    n-pentanol 843.79
    sec-butanol 1436.62
    n-hexane 958.21
    ethylene glycol 488.83
    NMP 1192.88
    cyclohexane 1364.2
    DMSO 936.43
    n-butyl acetate 641.59
    n-octanol 736.54
    chloroform 3431.58
    n-propyl acetate 489.27
    acetic acid 1780.86
    dichloromethane 2750.04
    cyclohexanone 1383.68
    propylene glycol 644.17
    isopropyl acetate 469.63
    DMAc 935.1
    2-ethoxyethanol 806.15
    isopentanol 868.51
    n-heptane 704.69
    ethyl formate 590.5
    1,2-dichloroethane 1128.52
    n-hexanol 1295.65
    2-methoxyethanol 1332.67
    isobutyl acetate 315.19
    tetrachloromethane 902.46
    n-pentyl acetate 504.56
    transcutol 1404.19
    n-heptanol 509.25
    ethylbenzene 388.54
    MIBK 345.93
    2-propoxyethanol 1050.57
    tert-butanol 1492.27
    MTBE 1012.43
    2-butoxyethanol 519.77
    propionic acid 1147.4
    o-xylene 428.32
    formic acid 591.14
    diethyl ether 1231.16
    m-xylene 368.66
    p-xylene 510.14
    chlorobenzene 691.1
    dimethyl carbonate 204.55
    n-octane 217.93
    formamide 467.59
    cyclopentanone 1110.53
    2-pentanone 629.02
    anisole 478.94
    cyclopentyl methyl ether 1158.98
    gamma-butyrolactone 1303.04
    1-methoxy-2-propanol 965.42
    pyridine 1121.23
    3-pentanone 573.92
    furfural 1007.19
    n-dodecane 142.04
    diethylene glycol 711.81
    diisopropyl ether 356.34
    tert-amyl alcohol 1436.51
    acetylacetone 544.18
    n-hexadecane 152.89
    acetophenone 405.86
    methyl propionate 604.37
    isopentyl acetate 499.73
    trichloroethylene 1708.06
    n-nonanol 601.27
    cyclohexanol 1694.46
    benzyl alcohol 454.09
    2-ethylhexanol 757.78
    isooctanol 381.26
    dipropyl ether 841.77
    1,2-dichlorobenzene 624.22
    ethyl lactate 261.25
    propylene carbonate 705.73
    n-methylformamide 619.14
    2-pentanol 965.81
    n-pentane 787.17
    1-propoxy-2-propanol 796.81
    1-methoxy-2-propyl acetate 476.31
    2-(2-methoxypropoxy) propanol 474.15
    mesitylene 243.25
    ε-caprolactone 1181.02
    p-cymene 295.31
    epichlorohydrin 1156.63
    1,1,1-trichloroethane 1363.41
    2-aminoethanol 844.75
    morpholine-4-carbaldehyde 1077.58
    sulfolane 1240.67
    2,2,4-trimethylpentane 265.32
    2-methyltetrahydrofuran 1782.8
    n-hexyl acetate 847.57
    isooctane 137.55
    2-(2-butoxyethoxy)ethanol 614.11
    sec-butyl acetate 329.15
    tert-butyl acetate 443.27
    decalin 364.8
    glycerin 677.3
    diglyme 940.18
    acrylic acid 827.17
    isopropyl myristate 332.81
    n-butyric acid 1260.16
    acetyl acetate 541.06
    di(2-ethylhexyl) phthalate 285.48
    ethyl propionate 468.87
    nitromethane 1259.31
    1,2-diethoxyethane 616.71
    benzonitrile 580.27
    trioctyl phosphate 227.48
    1-bromopropane 1229.12
    gamma-valerolactone 1230.39
    n-decanol 415.17
    triethyl phosphate 255.59
    4-methyl-2-pentanol 426.45
    propionitrile 899.75
    vinylene carbonate 711.39
    1,1,2-trichlorotrifluoroethane 1048.13
    DMS 411.23
    cumene 288.16
    2-octanol 453.18
    2-hexanone 497.38
    octyl acetate 429.56
    limonene 556.87
    1,2-dimethoxyethane 1222.23
    ethyl orthosilicate 267.32
    tributyl phosphate 276.8
    diacetone alcohol 472.78
    N,N-dimethylaniline 374.48
    acrylonitrile 847.7
    aniline 630.21
    1,3-propanediol 920.91
    bromobenzene 754.21
    dibromomethane 2084.5
    1,1,2,2-tetrachloroethane 1672.24
    2-methyl-cyclohexyl acetate 441.53
    tetrabutyl urea 344.98
    diisobutyl methanol 337.59
    2-phenylethanol 493.42
    styrene 452.12
    dioctyl adipate 433.88
    dimethyl sulfate 303.62
    ethyl butyrate 486.95
    methyl lactate 331.1
    butyl lactate 363.28
    diethyl carbonate 321.89
    propanediol butyl ether 527.31
    triethyl orthoformate 392.56
    p-tert-butyltoluene 279.63
    methyl 4-tert-butylbenzoate 429.52
    morpholine 1857.94
    tert-butylamine 1210.59
    n-dodecanol 318.15
    dimethoxymethane 645.12
    ethylene carbonate 623.37
    cyrene 381.61
    2-ethoxyethyl acetate 465.88
    2-ethylhexyl acetate 462.03
    1,2,4-trichlorobenzene 726.55
    4-methylpyridine 1017.97
    dibutyl ether 746.41
    2,6-dimethyl-4-heptanol 337.59
    DEF 761.29
    dimethyl isosorbide 715.43
    tetrachloroethylene 1234.34
    eugenol 372.96
    triacetin 632.02
    span 80 574.16
    1,4-butanediol 441.31
    1,1-dichloroethane 1336.03
    2-methyl-1-pentanol 684.41
    methyl formate 451.05
    2-methyl-1-butanol 979.61
    n-decane 253.63
    butyronitrile 966.95
    3,7-dimethyl-1-octanol 579.03
    1-chlorooctane 564.76
    1-chlorotetradecane 225.61
    n-nonane 298.13
    undecane 175.44
    tert-butylcyclohexane 328.79
    cyclooctane 399.35
    cyclopentanol 1519.19
    tetrahydropyran 2096.56
    tert-amyl methyl ether 840.71
    2,5,8-trioxanonane 698.68
    1-hexene 1245.09
    2-isopropoxyethanol 541.22
    2,2,2-trifluoroethanol 480.48
    methyl butyrate 599.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction