8-Hydroxyoctanoic acid

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  • Identifiers

    CAS number
    764-89-6

    Molecular formula
    C8H16O3

    SMILES
    C(CCCC(=O)O)CCCO

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Cheesy 35.48%
    Fatty 35.07%
    Odorless 33.5%
    Fruity 33.44%
    Oily 30.04%
    Sweet 29.69%
    Sour 27.76%
    Fresh 25.72%
    Buttery 25.61%
    Milky 25.5%

     

    Flavor
    Cheese 48.89%
    Fatty 47.08%
    Sour 41.38%
    Rancid 40.51%
    Sweat 39.88%
    Odorless 37.28%
    Waxy 36.55%
    Oily 34.76%
    Sweet 31.36%
    Cheesy 30.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    7.42 (neutral)

    Molecular weight
    160.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    305°C

    Flash point

    • 153.56 ˚C est.

  • Synonyms

    • 8-Hydroxyoctanoic acid
    • 764-89-6
    • DTXSID40227234
    • CHEBI:79162
    • RefChem:548161
    • DTXCID40149725
    • 634-761-0
    • 8-hydroxy-octanoic acid
    • Octanoic acid, 8-hydroxy-
    • MFCD00792446
    • 8-hydroxyoctanoate
    • 8-Hydroxycaprylic acid
    • 8-hydroxy caprylic acid
    • 8-Hydroxyoctanoicacid
    • omega-hydroxycaprylic acid
    • omega-hydroxyoctanoic acid
    • Octanoic acid,8-hydroxy-
    • SCHEMBL80794
    • orb1992351
    • SCHEMBL1008292
    • SCHEMBL10609923
    • 8-Hydroxyoctanoic acid, 98% (T)
    • LMFA01050023
    • AKOS006223694
    • DS-6067
    • s10749
    • 92348-62-4
    • BP-14142
    • SY022019
    • DB-056069
    • CS-0187285
    • ST50824782
    • F626586
    • Q27148223
    • 764-89-6

  • Applications

    8-Hydroxyoctanoic acid (CAS 764-89-6) is primarily used as a chemical building block and intermediate in industrial synthesis; in practice, it is employed as a precursor to esters and polyols for cosmetic and personal care formulations (emollient esters and functionalized surfactants), as a building block for biobased polymers and plastics (polyols and resin modifiers), and as a reactive intermediate in coatings and inks (functionalized polyols and surfactant components). It may also serve in cleaning products as a biodegradable surfactant precursor or coupling agent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 456.92
    methanol 1295.94
    isopropanol 165.08
    water 10.24
    ethyl acetate 62.13
    n-propanol 254.98
    acetone 126.14
    n-butanol 192.99
    acetonitrile 18.59
    DMF 573.6
    toluene 8.35
    isobutanol 192.04
    1,4-dioxane 92.74
    methyl acetate 30.41
    THF 416.65
    2-butanone 56.02
    n-pentanol 146.16
    sec-butanol 113.67
    n-hexane 9.71
    ethylene glycol 466.01
    NMP 517.89
    cyclohexane 5.75
    DMSO 1578.72
    n-butyl acetate 94.43
    n-octanol 51.14
    chloroform 16.41
    n-propyl acetate 69.59
    acetic acid 479.43
    dichloromethane 15.67
    cyclohexanone 205.95
    propylene glycol 434.5
    isopropyl acetate 65.09
    DMAc 277.88
    2-ethoxyethanol 360.09
    isopentanol 216.57
    n-heptane 5.32
    ethyl formate 67.39
    1,2-dichloroethane 27.71
    n-hexanol 168.93
    2-methoxyethanol 809.37
    isobutyl acetate 51.91
    tetrachloromethane 9.21
    n-pentyl acetate 50.67
    transcutol 839.06
    n-heptanol 70.2
    ethylbenzene 11.08
    MIBK 99.97
    2-propoxyethanol 355.11
    tert-butanol 364.04
    MTBE 62.11
    2-butoxyethanol 180.89
    propionic acid 260.62
    o-xylene 15.8
    formic acid 495.46
    diethyl ether 22.34
    m-xylene 18.38
    p-xylene 15.05
    chlorobenzene 13.81
    dimethyl carbonate 35.01
    n-octane 2.09
    formamide 510.31
    cyclopentanone 340.78
    2-pentanone 94.07
    anisole 37.89
    cyclopentyl methyl ether 163.4
    gamma-butyrolactone 400.19
    1-methoxy-2-propanol 506.92
    pyridine 48.04
    3-pentanone 41.74
    furfural 267.31
    n-dodecane 1.66
    diethylene glycol 400.62
    diisopropyl ether 20.23
    tert-amyl alcohol 229.35
    acetylacetone 158.14
    n-hexadecane 1.8
    acetophenone 60.4
    methyl propionate 64.11
    isopentyl acetate 98.94
    trichloroethylene 46.2
    n-nonanol 45.14
    cyclohexanol 169.44
    benzyl alcohol 73.64
    2-ethylhexanol 78.26
    isooctanol 59.19
    dipropyl ether 41.87
    1,2-dichlorobenzene 22.27
    ethyl lactate 78.06
    propylene carbonate 167.79
    n-methylformamide 384.98
    2-pentanol 97.13
    n-pentane 3.67
    1-propoxy-2-propanol 235.14
    1-methoxy-2-propyl acetate 128.08
    2-(2-methoxypropoxy) propanol 172.66
    mesitylene 18.02
    ε-caprolactone 191.7
    p-cymene 14.79
    epichlorohydrin 190.76
    1,1,1-trichloroethane 17.92
    2-aminoethanol 709.27
    morpholine-4-carbaldehyde 391.79
    sulfolane 719.99
    2,2,4-trimethylpentane 5.19
    2-methyltetrahydrofuran 185.53
    n-hexyl acetate 77.63
    isooctane 5.23
    2-(2-butoxyethoxy)ethanol 272.51
    sec-butyl acetate 47.45
    tert-butyl acetate 113.74
    decalin 6.15
    glycerin 666.22
    diglyme 391.03
    acrylic acid 228.99
    isopropyl myristate 27.71
    n-butyric acid 309.72
    acetyl acetate 47.23
    di(2-ethylhexyl) phthalate 47.56
    ethyl propionate 54.91
    nitromethane 304.78
    1,2-diethoxyethane 78.9
    benzonitrile 39.37
    trioctyl phosphate 37.53
    1-bromopropane 10.62
    gamma-valerolactone 425.27
    n-decanol 32.48
    triethyl phosphate 37.02
    4-methyl-2-pentanol 88.71
    propionitrile 28.7
    vinylene carbonate 111.15
    1,1,2-trichlorotrifluoroethane 304.72
    DMS 55.37
    cumene 14.59
    2-octanol 36.07
    2-hexanone 78.52
    octyl acetate 38.86
    limonene 23.81
    1,2-dimethoxyethane 295.29
    ethyl orthosilicate 36.52
    tributyl phosphate 45.45
    diacetone alcohol 282.41
    N,N-dimethylaniline 43.32
    acrylonitrile 51.17
    aniline 42.0
    1,3-propanediol 652.06
    bromobenzene 10.37
    dibromomethane 12.24
    1,1,2,2-tetrachloroethane 55.3
    2-methyl-cyclohexyl acetate 70.01
    tetrabutyl urea 64.33
    diisobutyl methanol 44.82
    2-phenylethanol 73.87
    styrene 10.46
    dioctyl adipate 58.75
    dimethyl sulfate 111.17
    ethyl butyrate 64.51
    methyl lactate 131.89
    butyl lactate 98.36
    diethyl carbonate 37.58
    propanediol butyl ether 245.49
    triethyl orthoformate 51.51
    p-tert-butyltoluene 15.79
    methyl 4-tert-butylbenzoate 88.15
    morpholine 211.68
    tert-butylamine 130.94
    n-dodecanol 22.88
    dimethoxymethane 176.03
    ethylene carbonate 91.11
    cyrene 160.86
    2-ethoxyethyl acetate 76.27
    2-ethylhexyl acetate 63.3
    1,2,4-trichlorobenzene 28.95
    4-methylpyridine 46.21
    dibutyl ether 29.56
    2,6-dimethyl-4-heptanol 44.82
    DEF 152.92
    dimethyl isosorbide 242.28
    tetrachloroethylene 57.99
    eugenol 107.31
    triacetin 93.46
    span 80 163.96
    1,4-butanediol 245.8
    1,1-dichloroethane 11.72
    2-methyl-1-pentanol 145.33
    methyl formate 159.88
    2-methyl-1-butanol 174.79
    n-decane 2.62
    butyronitrile 41.95
    3,7-dimethyl-1-octanol 61.47
    1-chlorooctane 12.03
    1-chlorotetradecane 5.21
    n-nonane 2.42
    undecane 1.99
    tert-butylcyclohexane 7.43
    cyclooctane 2.95
    cyclopentanol 287.99
    tetrahydropyran 74.71
    tert-amyl methyl ether 60.2
    2,5,8-trioxanonane 274.49
    1-hexene 23.33
    2-isopropoxyethanol 222.94
    2,2,2-trifluoroethanol 135.16
    methyl butyrate 94.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction