(8)-Gingerol

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  • Identifiers

    CAS number
    23513-08-8

    Molecular formula
    C19H30O4

    SMILES
    CCCCCCC[C@@H](CC(=O)CCC1=CC(=C(C=C1)O)OC)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Spicy 42.93%
    Sweet 39.57%
    Vanilla 29.96%
    Odorless 29.51%
    Milky 27.81%
    Balsamic 27.76%
    Creamy 26.92%
    Savory 26.13%
    Warm 25.64%
    Floral 25.53%

     

    Flavor
    Woody 42.67%
    Herbal 38.69%
    Mild 32.01%
    Odorless 30.83%
    Spicy 30.76%
    Bland 28.02%
    Warm 22.1%
    Oily 21.13%
    Parsley 20.63%
    Lovage 20.14%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    9.91 (weak base)

    Molecular weight
    322.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    486°C

    Flash point

    • 183.81 ˚C est.

  • Synonyms

    • 8-Gingerol
    • 23513-08-8
    • (8)-Gingerol
    • [8]-Gingerol
    • (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one
    • LB0IJB138K
    • DTXSID20178078
    • RefChem:25789
    • DTXCID50100569
    • (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
    • (S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one
    • MFCD00877794
    • 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
    • CHEMBL1095671
    • UNII-LB0IJB138K
    • 8-Gingerol (Standard)
    • (S)-(+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
    • 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-
    • orb1300194
    • SCHEMBL16488703
    • SCHEMBL29564345
    • CHEBI:81133
    • HY-N0447R
    • (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
    • HMS3887A05
    • [8]-Gingerol, analytical standard
    • HY-N0447
    • BDBM50317426
    • s9434
    • [8]-Gingerol, >=95% (HPLC)
    • AKOS025311538
    • CCG-267732
    • EBC-615947
    • FG09322
    • AC-34322
    • AS-71132
    • PD053776
    • CS-0008980
    • C17495
    • 462G352
    • 8-GINGEROL (CONSTITUENT OF GINGER) [DSC]
    • Q27155091
    • (5S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)dodecan-3-one
    • (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl) dodecan-3-one
    • 23513-08-8

  • Applications

    (8)-Gingerol (CAS 23513-08-8) is used as a flavor and aroma constituent in food and beverage formulations; as a fragrance component in cosmetics and personal care; as an intermediate or research reagent in pharmaceutical synthesis and related chemical processes; and as a bio-based aromatic precursor in industrial manufacturing and materials research.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1269.45
    methanol 2548.99
    isopropanol 531.34
    water 0.16
    ethyl acetate 570.8
    n-propanol 620.44
    acetone 1900.98
    n-butanol 333.37
    acetonitrile 413.72
    DMF 786.58
    toluene 43.72
    isobutanol 265.92
    1,4-dioxane 763.85
    methyl acetate 415.55
    THF 1454.67
    2-butanone 545.51
    n-pentanol 173.76
    sec-butanol 249.78
    n-hexane 0.68
    ethylene glycol 94.03
    NMP 281.68
    cyclohexane 4.74
    DMSO 3758.11
    n-butyl acetate 140.16
    n-octanol 45.21
    chloroform 366.87
    n-propyl acetate 210.43
    acetic acid 736.0
    dichloromethane 438.47
    cyclohexanone 600.07
    propylene glycol 225.42
    isopropyl acetate 256.1
    DMAc 631.02
    2-ethoxyethanol 565.4
    isopentanol 213.9
    n-heptane 0.89
    ethyl formate 253.24
    1,2-dichloroethane 436.57
    n-hexanol 96.51
    2-methoxyethanol 1347.03
    isobutyl acetate 119.45
    tetrachloromethane 32.51
    n-pentyl acetate 104.78
    transcutol 1105.49
    n-heptanol 51.88
    ethylbenzene 23.04
    MIBK 192.58
    2-propoxyethanol 342.75
    tert-butanol 561.78
    MTBE 245.59
    2-butoxyethanol 179.05
    propionic acid 317.89
    o-xylene 30.36
    formic acid 225.66
    diethyl ether 159.38
    m-xylene 30.34
    p-xylene 31.43
    chlorobenzene 87.72
    dimethyl carbonate 112.17
    n-octane 1.06
    formamide 484.62
    cyclopentanone 806.65
    2-pentanone 438.33
    anisole 98.58
    cyclopentyl methyl ether 209.93
    gamma-butyrolactone 727.89
    1-methoxy-2-propanol 682.61
    pyridine 280.58
    3-pentanone 176.46
    furfural 385.41
    n-dodecane 1.71
    diethylene glycol 317.28
    diisopropyl ether 26.06
    tert-amyl alcohol 272.2
    acetylacetone 621.2
    n-hexadecane 1.96
    acetophenone 124.5
    methyl propionate 293.68
    isopentyl acetate 132.46
    trichloroethylene 574.24
    n-nonanol 43.65
    cyclohexanol 215.07
    benzyl alcohol 123.33
    2-ethylhexanol 43.68
    isooctanol 46.1
    dipropyl ether 38.35
    1,2-dichlorobenzene 86.09
    ethyl lactate 105.83
    propylene carbonate 279.13
    n-methylformamide 483.31
    2-pentanol 112.45
    n-pentane 0.56
    1-propoxy-2-propanol 183.97
    1-methoxy-2-propyl acetate 198.91
    2-(2-methoxypropoxy) propanol 153.51
    mesitylene 19.31
    ε-caprolactone 412.18
    p-cymene 17.65
    epichlorohydrin 890.49
    1,1,1-trichloroethane 213.98
    2-aminoethanol 321.58
    morpholine-4-carbaldehyde 421.66
    sulfolane 856.35
    2,2,4-trimethylpentane 2.2
    2-methyltetrahydrofuran 424.19
    n-hexyl acetate 122.0
    isooctane 1.68
    2-(2-butoxyethoxy)ethanol 259.26
    sec-butyl acetate 116.98
    tert-butyl acetate 258.33
    decalin 3.65
    glycerin 275.39
    diglyme 546.09
    acrylic acid 209.67
    isopropyl myristate 42.7
    n-butyric acid 520.77
    acetyl acetate 253.47
    di(2-ethylhexyl) phthalate 53.09
    ethyl propionate 143.36
    nitromethane 1434.7
    1,2-diethoxyethane 197.27
    benzonitrile 115.02
    trioctyl phosphate 37.69
    1-bromopropane 87.98
    gamma-valerolactone 942.36
    n-decanol 30.96
    triethyl phosphate 53.15
    4-methyl-2-pentanol 62.08
    propionitrile 181.14
    vinylene carbonate 207.95
    1,1,2-trichlorotrifluoroethane 474.53
    DMS 118.12
    cumene 17.74
    2-octanol 33.11
    2-hexanone 183.27
    octyl acetate 57.64
    limonene 26.86
    1,2-dimethoxyethane 654.61
    ethyl orthosilicate 48.85
    tributyl phosphate 48.3
    diacetone alcohol 364.43
    N,N-dimethylaniline 56.36
    acrylonitrile 231.45
    aniline 107.7
    1,3-propanediol 599.33
    bromobenzene 74.25
    dibromomethane 215.18
    1,1,2,2-tetrachloroethane 495.69
    2-methyl-cyclohexyl acetate 86.73
    tetrabutyl urea 63.96
    diisobutyl methanol 29.18
    2-phenylethanol 96.44
    styrene 30.69
    dioctyl adipate 84.8
    dimethyl sulfate 217.95
    ethyl butyrate 95.88
    methyl lactate 160.76
    butyl lactate 111.94
    diethyl carbonate 71.17
    propanediol butyl ether 173.65
    triethyl orthoformate 68.69
    p-tert-butyltoluene 17.34
    methyl 4-tert-butylbenzoate 120.63
    morpholine 994.5
    tert-butylamine 128.67
    n-dodecanol 22.49
    dimethoxymethane 587.82
    ethylene carbonate 213.16
    cyrene 150.91
    2-ethoxyethyl acetate 201.5
    2-ethylhexyl acetate 84.1
    1,2,4-trichlorobenzene 104.48
    4-methylpyridine 193.68
    dibutyl ether 51.35
    2,6-dimethyl-4-heptanol 29.18
    DEF 269.02
    dimethyl isosorbide 251.45
    tetrachloroethylene 265.6
    eugenol 125.99
    triacetin 171.4
    span 80 128.34
    1,4-butanediol 155.43
    1,1-dichloroethane 277.58
    2-methyl-1-pentanol 121.88
    methyl formate 331.0
    2-methyl-1-butanol 168.4
    n-decane 2.79
    butyronitrile 193.73
    3,7-dimethyl-1-octanol 50.19
    1-chlorooctane 21.37
    1-chlorotetradecane 7.9
    n-nonane 2.13
    undecane 2.09
    tert-butylcyclohexane 3.27
    cyclooctane 1.09
    cyclopentanol 266.49
    tetrahydropyran 567.43
    tert-amyl methyl ether 111.96
    2,5,8-trioxanonane 334.39
    1-hexene 7.97
    2-isopropoxyethanol 271.38
    2,2,2-trifluoroethanol 167.79
    methyl butyrate 227.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction