(8)-Gingerdione

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  • Identifiers

    CAS number
    77334-06-6

    Molecular formula
    C19H28O4

    SMILES
    CCCCCCCC(=O)CC(=O)CCC1=CC(=C(C=C1)O)OC

    Safety labels

  • Odor profile

    Fragrance
    Spicy 43.51%
    Sweet 31.48%
    Savory 28.87%
    Woody 28.18%
    Warm 28.12%
    Vanilla 27.7%
    Milky 27.5%
    Odorless 26.31%
    Creamy 25.89%
    Dry 25.06%

     

    Flavor
    Herbal 41.59%
    Woody 32.53%
    Spicy 29.36%
    Mild 24.48%
    Odorless 24.45%
    Oily 23.94%
    Bland 23.31%
    Warm 22.45%
    Lovage 20.65%
    Parsley 20.45%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.7

    pKa est.
    9.91 (weak base)

    Molecular weight
    320.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    474°C

    Flash point

    • 180.96 ˚C est.

  • Synonyms

    • (8)-Gingerdione
    • 77334-06-6
    • [8]-Gingerdione
    • UNII-70E1Y63Q2L
    • 70E1Y63Q2L
    • 3,5-Dodecanedione, 1-(4-hydroxy-3-methoxyphenyl)-
    • 4-Dodecen-3-one, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (4Z)-
    • RefChem:25786
    • 8-GINGERDIONE: N=6 (CONSTITUENT OF GINGER)
    • 8-Gingerdione
    • 1-(4-Hydroxy-3-methoxyphenyl)dodecane-3,5-dione
    • orb2663475
    • CHEBI:175095
    • QDSRAFNZQKMHPZ-UHFFFAOYSA-N
    • DTXSID801316888
    • 8-Gingerdione(Mixture of tautomers)
    • 3-(octadecylcarbamoyl)-2-sulfo-propanoic Acid
    • Q27265857
    • 1-(4-Hydroxy-3-methoxyphenyl)-3,5-dodecanedione, 9CI
    • 8-GINGERDIONE : N=6 (CONSTITUENT OF GINGER) [DSC]
    • 77334-06-6

  • Applications

    Chemical name: (8)-Gingerdione; CAS number: 77334-06-6 is used as an odorant and fragrance ingredient in perfumery, providing a ginger-like spicy note; it may also function as a flavor precursor or contributor in flavor formulations. In cosmetics and personal care, it can be evaluated as a fragrance component; in household products, it may be used to impart a ginger-like aroma in cleaners and detergents. In industrial manufacturing, it can serve as an intermediate in organic synthesis and formulation development, subject to regulatory and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 690.58
    methanol 1303.96
    isopropanol 350.28
    water 0.08
    ethyl acetate 508.18
    n-propanol 373.98
    acetone 1654.36
    n-butanol 222.68
    acetonitrile 466.28
    DMF 772.46
    toluene 59.76
    isobutanol 180.87
    1,4-dioxane 633.26
    methyl acetate 444.83
    THF 1343.05
    2-butanone 560.02
    n-pentanol 140.34
    sec-butanol 192.24
    n-hexane 0.66
    ethylene glycol 57.71
    NMP 330.07
    cyclohexane 3.94
    DMSO 3099.44
    n-butyl acetate 140.6
    n-octanol 33.98
    chloroform 549.11
    n-propyl acetate 200.34
    acetic acid 551.12
    dichloromethane 690.96
    cyclohexanone 621.86
    propylene glycol 138.57
    isopropyl acetate 227.92
    DMAc 720.87
    2-ethoxyethanol 419.83
    isopentanol 158.58
    n-heptane 0.68
    ethyl formate 222.47
    1,2-dichloroethane 605.11
    n-hexanol 72.48
    2-methoxyethanol 878.79
    isobutyl acetate 113.27
    tetrachloromethane 37.45
    n-pentyl acetate 95.43
    transcutol 986.14
    n-heptanol 37.31
    ethylbenzene 30.89
    MIBK 182.65
    2-propoxyethanol 266.73
    tert-butanol 381.9
    MTBE 184.86
    2-butoxyethanol 140.17
    propionic acid 273.23
    o-xylene 37.53
    formic acid 147.0
    diethyl ether 135.96
    m-xylene 35.25
    p-xylene 42.31
    chlorobenzene 127.4
    dimethyl carbonate 115.62
    n-octane 0.85
    formamide 364.28
    cyclopentanone 858.03
    2-pentanone 384.89
    anisole 121.84
    cyclopentyl methyl ether 202.03
    gamma-butyrolactone 762.55
    1-methoxy-2-propanol 488.06
    pyridine 338.88
    3-pentanone 192.13
    furfural 435.81
    n-dodecane 1.47
    diethylene glycol 242.6
    diisopropyl ether 22.84
    tert-amyl alcohol 207.34
    acetylacetone 581.29
    n-hexadecane 1.73
    acetophenone 145.73
    methyl propionate 288.78
    isopentyl acetate 132.24
    trichloroethylene 823.65
    n-nonanol 33.84
    cyclohexanol 178.5
    benzyl alcohol 132.4
    2-ethylhexanol 38.46
    isooctanol 34.76
    dipropyl ether 33.89
    1,2-dichlorobenzene 120.98
    ethyl lactate 96.83
    propylene carbonate 293.28
    n-methylformamide 401.4
    2-pentanol 83.33
    n-pentane 0.47
    1-propoxy-2-propanol 146.94
    1-methoxy-2-propyl acetate 190.55
    2-(2-methoxypropoxy) propanol 146.63
    mesitylene 20.81
    ε-caprolactone 401.22
    p-cymene 19.08
    epichlorohydrin 1008.49
    1,1,1-trichloroethane 299.1
    2-aminoethanol 187.88
    morpholine-4-carbaldehyde 425.5
    sulfolane 867.24
    2,2,4-trimethylpentane 1.96
    2-methyltetrahydrofuran 423.55
    n-hexyl acetate 112.85
    isooctane 1.41
    2-(2-butoxyethoxy)ethanol 226.07
    sec-butyl acetate 119.16
    tert-butyl acetate 233.28
    decalin 3.86
    glycerin 186.89
    diglyme 494.31
    acrylic acid 194.11
    isopropyl myristate 41.58
    n-butyric acid 388.74
    acetyl acetate 235.67
    di(2-ethylhexyl) phthalate 53.21
    ethyl propionate 147.0
    nitromethane 1296.27
    1,2-diethoxyethane 184.17
    benzonitrile 138.73
    trioctyl phosphate 34.92
    1-bromopropane 126.03
    gamma-valerolactone 875.52
    n-decanol 24.87
    triethyl phosphate 55.84
    4-methyl-2-pentanol 48.56
    propionitrile 210.19
    vinylene carbonate 231.18
    1,1,2-trichlorotrifluoroethane 456.78
    DMS 131.92
    cumene 21.61
    2-octanol 25.12
    2-hexanone 185.56
    octyl acetate 55.37
    limonene 27.8
    1,2-dimethoxyethane 563.44
    ethyl orthosilicate 49.79
    tributyl phosphate 46.8
    diacetone alcohol 308.26
    N,N-dimethylaniline 67.13
    acrylonitrile 279.91
    aniline 127.84
    1,3-propanediol 349.24
    bromobenzene 113.87
    dibromomethane 343.74
    1,1,2,2-tetrachloroethane 662.63
    2-methyl-cyclohexyl acetate 87.63
    tetrabutyl urea 63.62
    diisobutyl methanol 26.14
    2-phenylethanol 98.46
    styrene 44.21
    dioctyl adipate 84.73
    dimethyl sulfate 234.96
    ethyl butyrate 100.04
    methyl lactate 139.36
    butyl lactate 97.6
    diethyl carbonate 75.28
    propanediol butyl ether 137.33
    triethyl orthoformate 69.46
    p-tert-butyltoluene 17.79
    methyl 4-tert-butylbenzoate 122.08
    morpholine 831.02
    tert-butylamine 93.19
    n-dodecanol 18.4
    dimethoxymethane 493.46
    ethylene carbonate 214.8
    cyrene 150.06
    2-ethoxyethyl acetate 189.48
    2-ethylhexyl acetate 86.58
    1,2,4-trichlorobenzene 142.09
    4-methylpyridine 252.28
    dibutyl ether 48.24
    2,6-dimethyl-4-heptanol 26.14
    DEF 269.53
    dimethyl isosorbide 250.86
    tetrachloroethylene 330.25
    eugenol 124.96
    triacetin 167.76
    span 80 112.98
    1,4-butanediol 108.15
    1,1-dichloroethane 406.03
    2-methyl-1-pentanol 103.62
    methyl formate 296.92
    2-methyl-1-butanol 129.7
    n-decane 2.37
    butyronitrile 195.06
    3,7-dimethyl-1-octanol 42.16
    1-chlorooctane 19.94
    1-chlorotetradecane 7.51
    n-nonane 1.8
    undecane 1.8
    tert-butylcyclohexane 3.25
    cyclooctane 0.83
    cyclopentanol 227.8
    tetrahydropyran 496.03
    tert-amyl methyl ether 97.92
    2,5,8-trioxanonane 312.13
    1-hexene 9.43
    2-isopropoxyethanol 221.3
    2,2,2-trifluoroethanol 144.66
    methyl butyrate 231.55

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction