6-O-Maltosyl-beta-cyclodextrin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    104723-60-6

    Molecular formula
    C54H90O45

    SMILES
    C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@@H]4[C@@H]([C@H]([C@H](O3)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]8[C@H](O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]9[C@H](O[C@@H]([C@@H]([C@H]9O)O)O[C@@H]1[C@H](O[C@H](O4)[C@@H]([C@H]1O)O)CO)CO)CO)CO)CO)CO)O)O)CO)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 79.77%
    Sweet 30.18%
    Alcoholic 21.95%
    Caramellic 16.63%
    Savory 15.66%
    Cooling 15.49%
    Clean 15.45%
    Milky 14.18%
    Fishy 13.87%
    Woody 13.59%

     

    Flavor
    Sweet 73.98%
    Odorless 49.07%
    Bitter 45.27%
    Sweet-like 31.51%
    Fatty 27.69%
    Cauliflower 22.35%
    Very slight 21.3%
    Alkaline 20.65%
    Soup 20.25%
    Naphthalic 19.84%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -18.8

    pKa est.
    51.9 (strong base)

    Molecular weight
    1459.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    3776°C

    Flash point

    • 426.43 ˚C est.

  • Synonyms

    • 6-O-Maltosyl-beta-cyclodextrin
    • DTXSID001021271
    • RefChem:914059
    • GlyTouCan:G01516VZ
    • DTXCID401506895
    • G01516VZ
    • 104723-60-6
    • 104723-60-6

  • Applications

    6-O-Maltosyl-beta-cyclodextrin, CAS 104723-60-6, is a highly water-soluble derivative of beta-cyclodextrin that serves as a hosting carrier for hydrophobic actives. It is commonly evaluated as a solubility-enhancing and stabilization excipient in pharmaceutical formulations, improving solubility and stability of poorly soluble APIs. It is also used as an encapsulation matrix for fragrances and flavors in perfumery, flavor, and cosmetics/personal care, enabling controlled release and enhanced sensory performance. In cosmetics, it can act as a carrier for vitamins and antioxidants, forming inclusion complexes with actives. In coatings, inks, and cleaning formulations, it may stabilize dyes and facilitate delivery of fragrance or odor-control actives. Use is formulation-dependent and subject to regulatory compliance.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.51
    methanol 28.88
    isopropanol 2.35
    water 10.47
    ethyl acetate 2.61
    n-propanol 3.75
    acetone 3.28
    n-butanol 2.22
    acetonitrile 1.53
    DMF 50.07
    toluene 0.97
    isobutanol 1.26
    1,4-dioxane 8.63
    methyl acetate 2.59
    THF 15.85
    2-butanone 2.9
    n-pentanol 1.24
    sec-butanol 1.51
    n-hexane 0.07
    ethylene glycol 16.91
    NMP 66.66
    cyclohexane 0.21
    DMSO 64.47
    n-butyl acetate 1.47
    n-octanol 1.53
    chloroform 1.42
    n-propyl acetate 1.07
    acetic acid 26.57
    dichloromethane 1.88
    cyclohexanone 5.19
    propylene glycol 12.15
    isopropyl acetate 1.41
    DMAc 38.99
    2-ethoxyethanol 13.32
    isopentanol 0.91
    n-heptane 0.24
    ethyl formate 4.02
    1,2-dichloroethane 1.2
    n-hexanol 1.15
    2-methoxyethanol 35.21
    isobutyl acetate 0.43
    tetrachloromethane 0.43
    n-pentyl acetate 2.51
    transcutol 24.14
    n-heptanol 1.98
    ethylbenzene 0.31
    MIBK 0.89
    2-propoxyethanol 12.18
    tert-butanol 0.98
    MTBE 0.61
    2-butoxyethanol 11.47
    propionic acid 6.98
    o-xylene 0.68
    formic acid 87.58
    diethyl ether 1.64
    m-xylene 0.57
    p-xylene 0.29
    chlorobenzene 0.49
    dimethyl carbonate 7.32
    n-octane 0.15
    formamide 71.84
    cyclopentanone 10.3
    2-pentanone 2.57
    anisole 0.86
    cyclopentyl methyl ether 4.37
    gamma-butyrolactone 18.18
    1-methoxy-2-propanol 19.36
    pyridine 6.52
    3-pentanone 2.07
    furfural 20.28
    n-dodecane 0.08
    diethylene glycol 20.2
    diisopropyl ether 0.29
    tert-amyl alcohol 0.97
    acetylacetone 4.51
    n-hexadecane 0.08
    acetophenone 1.72
    methyl propionate 4.77
    isopentyl acetate 0.91
    trichloroethylene 2.42
    n-nonanol 1.51
    cyclohexanol 1.93
    benzyl alcohol 2.09
    2-ethylhexanol 0.6
    isooctanol 1.01
    dipropyl ether 1.58
    1,2-dichlorobenzene 0.46
    ethyl lactate 3.03
    propylene carbonate 6.64
    n-methylformamide 28.01
    2-pentanol 1.03
    n-pentane 0.13
    1-propoxy-2-propanol 7.52
    1-methoxy-2-propyl acetate 5.25
    2-(2-methoxypropoxy) propanol 5.3
    mesitylene 0.3
    ε-caprolactone 7.48
    p-cymene 0.37
    epichlorohydrin 8.68
    1,1,1-trichloroethane 0.38
    2-aminoethanol 15.6
    morpholine-4-carbaldehyde 56.24
    sulfolane 41.6
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 4.22
    n-hexyl acetate 2.08
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 10.14
    sec-butyl acetate 0.6
    tert-butyl acetate 1.13
    decalin 0.07
    glycerin 36.88
    diglyme 18.72
    acrylic acid 13.7
    isopropyl myristate 0.62
    n-butyric acid 5.83
    acetyl acetate 2.22
    di(2-ethylhexyl) phthalate 1.06
    ethyl propionate 1.24
    nitromethane 25.3
    1,2-diethoxyethane 3.81
    benzonitrile 1.08
    trioctyl phosphate 1.01
    1-bromopropane 0.54
    gamma-valerolactone 33.08
    n-decanol 0.95
    triethyl phosphate 1.14
    4-methyl-2-pentanol 0.39
    propionitrile 1.09
    vinylene carbonate 7.59
    1,1,2-trichlorotrifluoroethane 23.77
    DMS 2.86
    cumene 0.18
    2-octanol 1.01
    2-hexanone 0.91
    octyl acetate 1.27
    limonene 0.56
    1,2-dimethoxyethane 9.23
    ethyl orthosilicate 1.0
    tributyl phosphate 0.81
    diacetone alcohol 3.72
    N,N-dimethylaniline 0.98
    acrylonitrile 2.61
    aniline 2.25
    1,3-propanediol 12.89
    bromobenzene 0.36
    dibromomethane 0.97
    1,1,2,2-tetrachloroethane 1.89
    2-methyl-cyclohexyl acetate 0.93
    tetrabutyl urea 1.69
    diisobutyl methanol 0.34
    2-phenylethanol 1.71
    styrene 0.34
    dioctyl adipate 1.36
    dimethyl sulfate 18.63
    ethyl butyrate 1.36
    methyl lactate 13.98
    butyl lactate 4.47
    diethyl carbonate 0.93
    propanediol butyl ether 11.3
    triethyl orthoformate 1.69
    p-tert-butyltoluene 0.37
    methyl 4-tert-butylbenzoate 3.6
    morpholine 14.85
    tert-butylamine 0.38
    n-dodecanol 0.6
    dimethoxymethane 19.7
    ethylene carbonate 4.83
    cyrene 10.52
    2-ethoxyethyl acetate 5.81
    2-ethylhexyl acetate 0.8
    1,2,4-trichlorobenzene 0.69
    4-methylpyridine 3.22
    dibutyl ether 0.97
    2,6-dimethyl-4-heptanol 0.34
    DEF 7.94
    dimethyl isosorbide 10.44
    tetrachloroethylene 1.97
    eugenol 3.97
    triacetin 4.7
    span 80 6.66
    1,4-butanediol 4.7
    1,1-dichloroethane 0.54
    2-methyl-1-pentanol 0.57
    methyl formate 19.48
    2-methyl-1-butanol 1.1
    n-decane 0.16
    butyronitrile 1.01
    3,7-dimethyl-1-octanol 0.61
    1-chlorooctane 0.45
    1-chlorotetradecane 0.15
    n-nonane 0.16
    undecane 0.11
    tert-butylcyclohexane 0.04
    cyclooctane 0.14
    cyclopentanol 3.36
    tetrahydropyran 3.46
    tert-amyl methyl ether 0.89
    2,5,8-trioxanonane 12.06
    1-hexene 0.21
    2-isopropoxyethanol 4.53
    2,2,2-trifluoroethanol 17.37
    methyl butyrate 1.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction