6-O-Hexopyranosyl-1,4-bis-O-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]hexopyranose

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  • Identifiers

    CAS number
    74565-72-3

    Molecular formula
    C34H42O19

    SMILES
    COC1=CC(=CC(=C1O)OC)C=CC(=O)OC2C(OC(C(C2O)O)OC(=O)C=CC3=CC(=C(C(=C3)OC)O)OC)COC4C(C(C(C(O4)CO)O)O)O

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  • Odor profile

    Fragrance
    Odorless 72.51%
    Vanilla 29.11%
    Milky 24.56%
    Savory 22.1%
    Sweet 20.91%
    Spicy 18.67%
    Balsamic 18.45%
    Creamy 16.95%
    Dairy 16.47%
    Warm 15.17%

     

    Flavor
    Bitter 75.87%
    Bland 37.1%
    Odorless 36.58%
    Sweet-like 25.47%
    Very mild 23.36%
    Parsley 20.17%
    Cedarleaf 19.76%
    Lovage 18.99%
    Eugenol 18.89%
    Ethyl benzoate 18.81%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.2

    pKa est.
    7.47 (neutral)

    Molecular weight
    754.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    4981°C

    Flash point

    • 255.06 ˚C est.

  • Synonyms

    • DTXSID801111478
    • 6-O-Hexopyranosyl-1,4-bis-O-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]hexopyranose
    • 74565-72-3
    • I(2)-D-Glucopyranose, 6-O-I(2)-D-glucopyranosyl-, 1,4-bis[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-2-propenoate]
    • 74565-72-3

  • Applications

    For 6-O-Hexopyranosyl-1,4-bis-O-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]hexopyranose (CAS 74565-72-3), the compound is viewed as a glycosylation-ready intermediate for phenylpropanoid derivatives and provides a scaffold for synthesizing glycosylated phenylpropanoids. Real-world applications include pharmaceutical synthesis, cosmetics and personal care formulation, fragrance and flavor industry precursor chemistry, and research in academic or industrial settings focused on developing glycosylation and esterification methodologies.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.16
    methanol 6.64
    isopropanol 2.24
    water 0.15
    ethyl acetate 1.8
    n-propanol 3.14
    acetone 9.51
    n-butanol 1.91
    acetonitrile 1.63
    DMF 21.37
    toluene 0.5
    isobutanol 1.17
    1,4-dioxane 12.21
    methyl acetate 2.84
    THF 24.26
    2-butanone 5.69
    n-pentanol 1.35
    sec-butanol 1.65
    n-hexane 0.04
    ethylene glycol 4.35
    NMP 20.63
    cyclohexane 0.11
    DMSO 90.9
    n-butyl acetate 0.52
    n-octanol 0.88
    chloroform 1.38
    n-propyl acetate 0.79
    acetic acid 9.72
    dichloromethane 1.9
    cyclohexanone 6.8
    propylene glycol 3.67
    isopropyl acetate 0.82
    DMAc 22.67
    2-ethoxyethanol 7.94
    isopentanol 0.87
    n-heptane 0.07
    ethyl formate 2.66
    1,2-dichloroethane 1.69
    n-hexanol 0.6
    2-methoxyethanol 15.32
    isobutyl acetate 0.27
    tetrachloromethane 0.24
    n-pentyl acetate 1.04
    transcutol 6.16
    n-heptanol 0.84
    ethylbenzene 0.18
    MIBK 0.81
    2-propoxyethanol 3.98
    tert-butanol 1.22
    MTBE 0.71
    2-butoxyethanol 3.34
    propionic acid 2.98
    o-xylene 0.3
    formic acid 11.07
    diethyl ether 1.61
    m-xylene 0.2
    p-xylene 0.2
    chlorobenzene 0.39
    dimethyl carbonate 2.37
    n-octane 0.06
    formamide 11.74
    cyclopentanone 12.9
    2-pentanone 3.04
    anisole 0.64
    cyclopentyl methyl ether 2.11
    gamma-butyrolactone 11.65
    1-methoxy-2-propanol 6.55
    pyridine 5.07
    3-pentanone 2.22
    furfural 7.93
    n-dodecane 0.03
    diethylene glycol 4.71
    diisopropyl ether 0.16
    tert-amyl alcohol 0.99
    acetylacetone 4.57
    n-hexadecane 0.04
    acetophenone 1.01
    methyl propionate 2.69
    isopentyl acetate 0.33
    trichloroethylene 2.49
    n-nonanol 0.89
    cyclohexanol 1.47
    benzyl alcohol 1.27
    2-ethylhexanol 0.26
    isooctanol 0.44
    dipropyl ether 0.65
    1,2-dichlorobenzene 0.28
    ethyl lactate 1.03
    propylene carbonate 2.18
    n-methylformamide 9.6
    2-pentanol 0.73
    n-pentane 0.06
    1-propoxy-2-propanol 1.92
    1-methoxy-2-propyl acetate 1.14
    2-(2-methoxypropoxy) propanol 2.07
    mesitylene 0.09
    ε-caprolactone 4.52
    p-cymene 0.09
    epichlorohydrin 9.53
    1,1,1-trichloroethane 0.46
    2-aminoethanol 4.39
    morpholine-4-carbaldehyde 17.84
    sulfolane 23.85
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 4.56
    n-hexyl acetate 1.05
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 3.6
    sec-butyl acetate 0.34
    tert-butyl acetate 0.62
    decalin 0.02
    glycerin 7.9
    diglyme 6.61
    acrylic acid 3.91
    isopropyl myristate 0.31
    n-butyric acid 2.49
    acetyl acetate 1.05
    di(2-ethylhexyl) phthalate 0.45
    ethyl propionate 0.72
    nitromethane 15.78
    1,2-diethoxyethane 1.92
    benzonitrile 0.71
    trioctyl phosphate 0.42
    1-bromopropane 0.67
    gamma-valerolactone 22.89
    n-decanol 0.57
    triethyl phosphate 0.34
    4-methyl-2-pentanol 0.24
    propionitrile 1.24
    vinylene carbonate 2.26
    1,1,2-trichlorotrifluoroethane 9.64
    DMS 0.91
    cumene 0.09
    2-octanol 0.48
    2-hexanone 1.45
    octyl acetate 0.64
    limonene 0.16
    1,2-dimethoxyethane 8.65
    ethyl orthosilicate 0.3
    tributyl phosphate 0.35
    diacetone alcohol 1.92
    N,N-dimethylaniline 0.46
    acrylonitrile 2.04
    aniline 1.15
    1,3-propanediol 6.11
    bromobenzene 0.27
    dibromomethane 0.98
    1,1,2,2-tetrachloroethane 2.21
    2-methyl-cyclohexyl acetate 0.35
    tetrabutyl urea 0.87
    diisobutyl methanol 0.12
    2-phenylethanol 0.64
    styrene 0.21
    dioctyl adipate 0.71
    dimethyl sulfate 5.08
    ethyl butyrate 0.52
    methyl lactate 3.15
    butyl lactate 1.2
    diethyl carbonate 0.31
    propanediol butyl ether 3.07
    triethyl orthoformate 0.49
    p-tert-butyltoluene 0.08
    methyl 4-tert-butylbenzoate 1.09
    morpholine 13.24
    tert-butylamine 0.35
    n-dodecanol 0.35
    dimethoxymethane 10.51
    ethylene carbonate 1.88
    cyrene 3.94
    2-ethoxyethyl acetate 2.28
    2-ethylhexyl acetate 0.26
    1,2,4-trichlorobenzene 0.45
    4-methylpyridine 2.22
    dibutyl ether 0.59
    2,6-dimethyl-4-heptanol 0.12
    DEF 4.03
    dimethyl isosorbide 2.46
    tetrachloroethylene 1.45
    eugenol 1.2
    triacetin 1.4
    span 80 1.95
    1,4-butanediol 2.7
    1,1-dichloroethane 0.78
    2-methyl-1-pentanol 0.63
    methyl formate 8.46
    2-methyl-1-butanol 0.99
    n-decane 0.07
    butyronitrile 1.01
    3,7-dimethyl-1-octanol 0.3
    1-chlorooctane 0.25
    1-chlorotetradecane 0.09
    n-nonane 0.07
    undecane 0.05
    tert-butylcyclohexane 0.01
    cyclooctane 0.04
    cyclopentanol 2.82
    tetrahydropyran 4.73
    tert-amyl methyl ether 0.64
    2,5,8-trioxanonane 4.52
    1-hexene 0.17
    2-isopropoxyethanol 2.95
    2,2,2-trifluoroethanol 4.17
    methyl butyrate 1.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction