(6)-Gingerol

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  • Identifiers

    CAS number
    23513-14-6

    Molecular formula
    C17H26O4

    SMILES
    CCCCC[C@@H](CC(=O)CCC1=CC(=C(C=C1)O)OC)O

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 45.69%
    Spicy 43.84%
    Vanilla 35.59%
    Creamy 29.12%
    Balsamic 27.86%
    Milky 27.29%
    Savory 26.57%
    Odorless 26.49%
    Fruity 25.8%
    Warm 25.67%

     

    Flavor
    Woody 37.72%
    Herbal 35.09%
    Spicy 31.45%
    Odorless 31.16%
    Mild 30.63%
    Bland 25.66%
    Warm 20.73%
    Parsley 20.32%
    Ham 20.23%
    Ethyl benzoate 20.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    10.05 (weak base)

    Molecular weight
    294.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    455°C

    Flash point

    • 177.47 ˚C est.

  • Synonyms

    • 6-Gingerol
    • gingerol
    • 23513-14-6
    • [6]-Gingerol
    • (6)-Gingerol
    • (S)-(+)-[6]Gingerol
    • (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
    • (S)-(6)-Gingerol
    • DTXSID3041035
    • (+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
    • 925QK2Z900
    • (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl)decan-3-one
    • 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-
    • CHEBI:10136
    • (S)-(+)-(6)Gingerol
    • RefChem:5858
    • DTXCID1021035
    • (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
    • 1391-73-7
    • 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
    • MFCD00210507
    • (+)-[6]-Gingerol
    • (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
    • C17-H26-O4
    • CHEMBL402978
    • BDBM50317427
    • (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
    • 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-
    • (S)-(+)-[6]Gingerol;6-Gingerol
    • UNII-925QK2Z900
    • NLDDIKRKFXEWBK-AWEZNQCLSA-N
    • [6]-Gingerol (Standard)
    • CBiol_001786
    • SCHEMBL32102
    • BSPBio_001347
    • KBioGR_000067
    • KBioSS_000067
    • (6)-GINGEROL [MI]
    • CHEMBL446043
    • GTPL2428
    • orb1304232
    • SHG-02
    • SCHEMBL29475335
    • KBio2_000067
    • KBio2_002635
    • KBio2_005203
    • KBio3_000133
    • KBio3_000134
    • Bio1_000072
    • Bio1_000561
    • Bio1_001050
    • Bio2_000067
    • Bio2_000547
    • HMS1361D09
    • HMS1791D09
    • HMS1989D09
    • HMS3402D09
    • SRCG-00265
    • [6]-Gingerol, analytical standard
    • BDBM50275147
    • CA-422
    • HY-14615R
    • MSK000358
    • s3836
    • [6]-Gingerol, >=98% (HPLC)
    • AKOS015888215
    • CCG-208033
    • CCG-208214
    • CS-6333
    • EBC-459094
    • FG09324
    • IDI1_033817
    • NCGC00163131-01
    • NCGC00163131-02
    • NCGC00163131-03
    • AC-33934
    • DS-12369
    • HY-14615
    • NS00027445
    • C10462
    • 513G146
    • 6-GINGEROL (CONSTITUENT OF GINGER) [DSC]
    • Q421081
    • SR-05000002341
    • SR-05000002341-2
    • BRD-K26117720-001-02-2
    • 5-Hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)-3-decanone
    • (S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)-3-decanone
    • (S)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl-3-decanone
    • [1-(4''-hydroxy-3''-methoxyphenyl)-5-hydroxy-3-decanone]
    • 1-(4'-HYDROXY-3'-METHOXYPHENYL)-5-HYDROXY-3-DECANONE
    • SHG-02, 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone, 6-Gingerol
    • 23513-14-6

  • Applications

    (6)-Gingerol, CAS 23513-14-6, is a natural aroma and flavor component derived from ginger and is widely used in fragrance and flavor applications. In perfumery, it contributes ginger notes and can serve as a fragrance ingredient; in the food and beverage sector it is evaluated as a flavoring agent in product formulations. In cosmetics and personal care, it is used as a natural scent additive in creams, lotions, and shampoos. In household products, it provides a ginger-like aroma in cleaners, detergents, and air fresheners. In pharmaceutical research and related chemical synthesis, it is often explored as a bioactive lead in natural product studies and as an intermediate for the synthesis of related aroma compounds.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1509.12
    methanol 3284.95
    isopropanol 588.59
    water 0.3
    ethyl acetate 467.47
    n-propanol 641.08
    acetone 1458.84
    n-butanol 342.98
    acetonitrile 423.84
    DMF 643.18
    toluene 32.76
    isobutanol 251.79
    1,4-dioxane 764.0
    methyl acetate 354.71
    THF 1187.41
    2-butanone 391.53
    n-pentanol 177.47
    sec-butanol 232.85
    n-hexane 0.5
    ethylene glycol 168.23
    NMP 205.16
    cyclohexane 2.95
    DMSO 3272.34
    n-butyl acetate 110.25
    n-octanol 43.26
    chloroform 255.44
    n-propyl acetate 151.57
    acetic acid 771.67
    dichloromethane 311.66
    cyclohexanone 407.96
    propylene glycol 320.23
    isopropyl acetate 189.11
    DMAc 487.48
    2-ethoxyethanol 581.42
    isopentanol 201.98
    n-heptane 0.71
    ethyl formate 228.17
    1,2-dichloroethane 297.3
    n-hexanol 100.72
    2-methoxyethanol 1472.81
    isobutyl acetate 91.47
    tetrachloromethane 18.56
    n-pentyl acetate 67.4
    transcutol 995.74
    n-heptanol 46.62
    ethylbenzene 18.71
    MIBK 142.97
    2-propoxyethanol 333.05
    tert-butanol 589.09
    MTBE 169.9
    2-butoxyethanol 154.58
    propionic acid 303.25
    o-xylene 23.78
    formic acid 306.13
    diethyl ether 114.65
    m-xylene 25.68
    p-xylene 24.51
    chlorobenzene 63.97
    dimethyl carbonate 92.45
    n-octane 0.84
    formamide 578.27
    cyclopentanone 544.87
    2-pentanone 313.13
    anisole 85.73
    cyclopentyl methyl ether 154.49
    gamma-butyrolactone 549.4
    1-methoxy-2-propanol 679.89
    pyridine 210.82
    3-pentanone 119.75
    furfural 322.31
    n-dodecane 1.6
    diethylene glycol 387.7
    diisopropyl ether 19.65
    tert-amyl alcohol 248.56
    acetylacetone 467.94
    n-hexadecane 1.82
    acetophenone 101.33
    methyl propionate 228.3
    isopentyl acetate 102.74
    trichloroethylene 399.86
    n-nonanol 40.29
    cyclohexanol 183.83
    benzyl alcohol 116.61
    2-ethylhexanol 39.99
    isooctanol 40.13
    dipropyl ether 29.1
    1,2-dichlorobenzene 62.02
    ethyl lactate 94.22
    propylene carbonate 216.31
    n-methylformamide 463.32
    2-pentanol 107.8
    n-pentane 0.4
    1-propoxy-2-propanol 168.64
    1-methoxy-2-propyl acetate 160.45
    2-(2-methoxypropoxy) propanol 143.84
    mesitylene 15.99
    ε-caprolactone 294.98
    p-cymene 14.85
    epichlorohydrin 688.4
    1,1,1-trichloroethane 132.84
    2-aminoethanol 449.03
    morpholine-4-carbaldehyde 370.11
    sulfolane 623.68
    2,2,4-trimethylpentane 1.68
    2-methyltetrahydrofuran 320.81
    n-hexyl acetate 89.55
    isooctane 1.44
    2-(2-butoxyethoxy)ethanol 233.29
    sec-butyl acetate 84.64
    tert-butyl acetate 187.54
    decalin 2.86
    glycerin 377.66
    diglyme 459.24
    acrylic acid 210.87
    isopropyl myristate 35.45
    n-butyric acid 437.66
    acetyl acetate 201.86
    di(2-ethylhexyl) phthalate 47.06
    ethyl propionate 105.69
    nitromethane 1289.41
    1,2-diethoxyethane 161.78
    benzonitrile 97.71
    trioctyl phosphate 33.36
    1-bromopropane 57.02
    gamma-valerolactone 703.59
    n-decanol 30.15
    triethyl phosphate 43.4
    4-methyl-2-pentanol 57.66
    propionitrile 163.67
    vinylene carbonate 173.09
    1,1,2-trichlorotrifluoroethane 381.82
    DMS 95.44
    cumene 15.05
    2-octanol 28.14
    2-hexanone 132.03
    octyl acetate 47.17
    limonene 21.22
    1,2-dimethoxyethane 585.14
    ethyl orthosilicate 39.87
    tributyl phosphate 41.02
    diacetone alcohol 292.84
    N,N-dimethylaniline 49.07
    acrylonitrile 220.34
    aniline 93.54
    1,3-propanediol 741.79
    bromobenzene 51.38
    dibromomethane 145.95
    1,1,2,2-tetrachloroethane 330.8
    2-methyl-cyclohexyl acetate 68.7
    tetrabutyl urea 54.19
    diisobutyl methanol 26.69
    2-phenylethanol 90.5
    styrene 24.66
    dioctyl adipate 68.57
    dimethyl sulfate 171.24
    ethyl butyrate 73.44
    methyl lactate 149.97
    butyl lactate 81.79
    diethyl carbonate 57.04
    propanediol butyl ether 164.35
    triethyl orthoformate 54.38
    p-tert-butyltoluene 14.73
    methyl 4-tert-butylbenzoate 98.7
    morpholine 929.51
    tert-butylamine 120.25
    n-dodecanol 22.72
    dimethoxymethane 527.31
    ethylene carbonate 166.86
    cyrene 135.97
    2-ethoxyethyl acetate 145.45
    2-ethylhexyl acetate 65.19
    1,2,4-trichlorobenzene 77.14
    4-methylpyridine 152.08
    dibutyl ether 40.15
    2,6-dimethyl-4-heptanol 26.69
    DEF 193.4
    dimethyl isosorbide 214.0
    tetrachloroethylene 180.04
    eugenol 108.98
    triacetin 129.15
    span 80 117.6
    1,4-butanediol 199.31
    1,1-dichloroethane 185.28
    2-methyl-1-pentanol 111.25
    methyl formate 324.32
    2-methyl-1-butanol 149.79
    n-decane 2.4
    butyronitrile 173.5
    3,7-dimethyl-1-octanol 45.33
    1-chlorooctane 17.23
    1-chlorotetradecane 7.05
    n-nonane 1.8
    undecane 1.89
    tert-butylcyclohexane 2.59
    cyclooctane 0.85
    cyclopentanol 225.08
    tetrahydropyran 431.18
    tert-amyl methyl ether 83.07
    2,5,8-trioxanonane 306.28
    1-hexene 5.79
    2-isopropoxyethanol 264.42
    2,2,2-trifluoroethanol 162.45
    methyl butyrate 165.5

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction