Molecular formula
C8H10N2

SMILES
C[C@H]1CCC2=NC=CN=C12

Fragrance
Nutty	86.34%
Roasted	86.3%
Earthy	71.49%
Musty	63.11%
Coffee	62.78%
Hazelnut	57.0%
Burnt	56.47%
Potato	54.76%
Cocoa	51.07%
Popcorn	50.95%

 

Flavor
Roasted	66.2%
Earthy	56.13%
Nut	51.79%
Nutty	50.86%
Potato	49.43%
Musty	48.44%
Roast	47.64%
Corn	45.03%
Coffee	44.17%
Peanut	42.65%

 

Odor impact est.
High

XLogP3-AA
0.8

pKa est.
4.62 (weak acid)

Molecular weight
134.18 g/mol

Vapor pressure est.

• hPa @ 20°C
• hPa @ 25°C

Evaporation rate
Moderate

Boiling point est.
233°C

Flash point

• 92.86 ˚C est.

(5S)-5-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine is used primarily as a chiral building block and synthetic intermediate in pharmaceutical research and development, supporting the construction of heterocyclic drug candidates and enabling medicinal chemistry libraries; it may also serve as a specialized scaffold for synthesizing related compounds and can be explored as a fragrance intermediate for niche perfumery applications, depending on formulation needs.

gpt-5-nano

Solvent	Solubility (g/L)
ethanol	254.04
methanol	444.37
isopropanol	146.75
water	10.2
ethyl acetate	213.8
n-propanol	182.96
acetone	276.15
n-butanol	174.52
acetonitrile	274.05
DMF	346.0
toluene	176.28
isobutanol	159.33
1,4-dioxane	414.58
methyl acetate	208.75
THF	454.02
2-butanone	233.08
n-pentanol	153.16
sec-butanol	136.24
n-hexane	23.99
ethylene glycol	102.6
NMP	396.52
cyclohexane	31.17
DMSO	358.88
n-butyl acetate	250.91
n-octanol	101.51
chloroform	917.6
n-propyl acetate	167.74
acetic acid	317.57
dichloromethane	953.68
cyclohexanone	352.27
propylene glycol	93.37
isopropyl acetate	145.31
DMAc	259.76
2-ethoxyethanol	240.28
isopentanol	167.14
n-heptane	24.56
ethyl formate	209.98
1,2-dichloroethane	434.2
n-hexanol	179.2
2-methoxyethanol	322.07
isobutyl acetate	131.48
tetrachloromethane	215.32
n-pentyl acetate	169.3
transcutol	801.42
n-heptanol	108.66
ethylbenzene	86.81
MIBK	155.44
2-propoxyethanol	296.92
tert-butanol	149.59
MTBE	153.68
2-butoxyethanol	201.74
propionic acid	184.76
o-xylene	112.61
formic acid	187.5
diethyl ether	174.43
m-xylene	125.29
p-xylene	125.89
chlorobenzene	318.12
dimethyl carbonate	112.55
n-octane	14.99
formamide	182.57
cyclopentanone	422.86
2-pentanone	191.56
anisole	165.6
cyclopentyl methyl ether	220.34
gamma-butyrolactone	510.51
1-methoxy-2-propanol	206.45
pyridine	402.89
3-pentanone	169.0
furfural	553.65
n-dodecane	15.49
diethylene glycol	271.39
diisopropyl ether	70.39
tert-amyl alcohol	141.41
acetylacetone	242.7
n-hexadecane	17.11
acetophenone	172.9
methyl propionate	174.01
isopentyl acetate	226.5
trichloroethylene	841.97
n-nonanol	88.59
cyclohexanol	145.9
benzyl alcohol	159.61
2-ethylhexanol	119.67
isooctanol	95.03
dipropyl ether	115.67
1,2-dichlorobenzene	301.95
ethyl lactate	93.13
propylene carbonate	309.87
n-methylformamide	236.41
2-pentanol	113.72
n-pentane	26.84
1-propoxy-2-propanol	199.55
1-methoxy-2-propyl acetate	204.03
2-(2-methoxypropoxy) propanol	175.09
mesitylene	86.33
ε-caprolactone	322.7
p-cymene	75.81
epichlorohydrin	548.38
1,1,1-trichloroethane	411.75
2-aminoethanol	141.63
morpholine-4-carbaldehyde	398.34
sulfolane	528.37
2,2,4-trimethylpentane	23.94
2-methyltetrahydrofuran	338.87
n-hexyl acetate	208.82
isooctane	19.01
2-(2-butoxyethoxy)ethanol	241.12
sec-butyl acetate	115.73
tert-butyl acetate	153.06
decalin	28.27
glycerin	147.86
diglyme	414.12
acrylic acid	203.47
isopropyl myristate	84.78
n-butyric acid	239.65
acetyl acetate	167.78
di(2-ethylhexyl) phthalate	101.56
ethyl propionate	131.84
nitromethane	398.45
1,2-diethoxyethane	261.35
benzonitrile	283.09
trioctyl phosphate	71.13
1-bromopropane	234.94
gamma-valerolactone	500.81
n-decanol	70.22
triethyl phosphate	81.45
4-methyl-2-pentanol	85.71
propionitrile	212.58
vinylene carbonate	314.46
1,1,2-trichlorotrifluoroethane	319.67
DMS	180.45
cumene	75.93
2-octanol	79.85
2-hexanone	163.9
octyl acetate	105.65
limonene	92.76
1,2-dimethoxyethane	311.13
ethyl orthosilicate	79.85
tributyl phosphate	93.69
diacetone alcohol	166.82
N,N-dimethylaniline	119.18
acrylonitrile	281.03
aniline	202.16
1,3-propanediol	179.92
bromobenzene	358.1
dibromomethane	567.77
1,1,2,2-tetrachloroethane	549.42
2-methyl-cyclohexyl acetate	131.79
tetrabutyl urea	106.52
diisobutyl methanol	73.19
2-phenylethanol	187.27
styrene	107.84
dioctyl adipate	112.02
dimethyl sulfate	166.4
ethyl butyrate	158.35
methyl lactate	112.19
butyl lactate	128.09
diethyl carbonate	113.27
propanediol butyl ether	170.32
triethyl orthoformate	111.17
p-tert-butyltoluene	68.84
methyl 4-tert-butylbenzoate	157.58
morpholine	332.14
tert-butylamine	111.87
n-dodecanol	57.21
dimethoxymethane	251.61
ethylene carbonate	250.81
cyrene	163.72
2-ethoxyethyl acetate	233.33
2-ethylhexyl acetate	179.45
1,2,4-trichlorobenzene	331.74
4-methylpyridine	361.08
dibutyl ether	125.05
2,6-dimethyl-4-heptanol	73.19
DEF	221.33
dimethyl isosorbide	282.0
tetrachloroethylene	431.91
eugenol	176.05
triacetin	178.1
span 80	155.2
1,4-butanediol	111.78
1,1-dichloroethane	396.75
2-methyl-1-pentanol	150.74
methyl formate	230.43
2-methyl-1-butanol	165.49
n-decane	22.55
butyronitrile	221.06
3,7-dimethyl-1-octanol	102.97
1-chlorooctane	85.66
1-chlorotetradecane	39.45
n-nonane	21.07
undecane	18.11
tert-butylcyclohexane	28.53
cyclooctane	15.78
cyclopentanol	176.76
tetrahydropyran	259.8
tert-amyl methyl ether	123.49
2,5,8-trioxanonane	268.68
1-hexene	84.12
2-isopropoxyethanol	171.21
2,2,2-trifluoroethanol	149.07
methyl butyrate	178.12

Scent© AI