5,6-Dihydro-2H-pyran-2-carbaldehyde

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    53897-26.0

    Molecular formula
    C6H8O2

    SMILES
    C1COC(C=C1)C=O

  • Odor profile

    Fragrance
    Green 52.46%
    Spicy 48.74%
    Fruity 46.15%
    Sweet 45.72%
    Nutty 37.21%
    Herbal 36.53%
    Caramellic 35.7%
    Pungent 32.13%
    Almond 31.7%
    Aldehydic 27.25%

     

    Flavor
    Bitter 28.53%
    Oily 25.55%
    Spice 24.12%
    Spicy 22.59%
    Shrimp 21.53%
    Fatty 20.35%
    Cauliflower 20.3%
    Formyl 20.0%
    Red hots 19.99%
    Clam 19.93%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.5

    pKa est.
    5.49 (weak acid)

    Molecular weight
    112.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    184°C

    Flash point

    • 64.01 ˚C est.

  • Synonyms

    • 5,6-Dihydro-2H-pyran-2-carbaldehyde
    • 2H-Pyran-2-carboxaldehyde, 5,6-dihydro-
    • SCHEMBL7179192
    • ABXVWFMVVXQBEH-UHFFFAOYSA-N
    • 5,6-Dihydro-2H-pyran-2-carbaldehyde #
    • 53897-26-0
    • DB-295855

  • Applications

    5,6-Dihydro-2H-pyran-2-carbaldehyde (CAS 53897-26.0) is primarily used as an intermediate in the synthesis of fragrance and flavor-related compounds, enabling pyran-based aroma chemistries in broad industrial applications. In cosmetics and personal care, it may serve as an aroma ingredient or fragrance precursor in formulations for skincare and makeup products. In industrial manufacturing, it acts as an organic synthesis intermediate to access specialized pyran-containing chemicals and resins, supporting resin, coating, or polymer-related applications. It may also be used as a reactive aldehyde building block for resin formation in coatings and inks, where its ring structure facilitates functionalization and crosslinking.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 144.18
    methanol 270.38
    isopropanol 73.6
    water 6.41
    ethyl acetate 177.64
    n-propanol 105.33
    acetone 173.04
    n-butanol 78.52
    acetonitrile 231.93
    DMF 512.27
    toluene 60.81
    isobutanol 61.02
    1,4-dioxane 319.39
    methyl acetate 197.73
    THF 212.28
    2-butanone 117.68
    n-pentanol 53.6
    sec-butanol 54.71
    n-hexane 3.33
    ethylene glycol 135.11
    NMP 298.57
    cyclohexane 12.41
    DMSO 730.95
    n-butyl acetate 79.47
    n-octanol 32.37
    chloroform 346.46
    n-propyl acetate 72.6
    acetic acid 327.09
    dichloromethane 360.43
    cyclohexanone 160.34
    propylene glycol 85.31
    isopropyl acetate 64.82
    DMAc 284.92
    2-ethoxyethanol 148.98
    isopentanol 58.75
    n-heptane 6.41
    ethyl formate 127.93
    1,2-dichloroethane 239.06
    n-hexanol 62.64
    2-methoxyethanol 319.65
    isobutyl acetate 38.46
    tetrachloromethane 44.73
    n-pentyl acetate 38.9
    transcutol 753.47
    n-heptanol 25.46
    ethylbenzene 23.12
    MIBK 47.49
    2-propoxyethanol 149.72
    tert-butanol 90.36
    MTBE 46.57
    2-butoxyethanol 77.73
    propionic acid 196.85
    o-xylene 46.14
    formic acid 249.33
    diethyl ether 80.06
    m-xylene 44.98
    p-xylene 30.47
    chlorobenzene 117.44
    dimethyl carbonate 80.89
    n-octane 2.58
    formamide 315.83
    cyclopentanone 181.41
    2-pentanone 87.28
    anisole 76.15
    cyclopentyl methyl ether 88.75
    gamma-butyrolactone 298.38
    1-methoxy-2-propanol 171.68
    pyridine 283.18
    3-pentanone 72.81
    furfural 356.82
    n-dodecane 3.34
    diethylene glycol 226.92
    diisopropyl ether 18.19
    tert-amyl alcohol 58.85
    acetylacetone 141.04
    n-hexadecane 3.76
    acetophenone 79.64
    methyl propionate 144.41
    isopentyl acetate 57.38
    trichloroethylene 430.26
    n-nonanol 29.54
    cyclohexanol 78.48
    benzyl alcohol 76.04
    2-ethylhexanol 37.04
    isooctanol 21.91
    dipropyl ether 43.75
    1,2-dichlorobenzene 101.16
    ethyl lactate 57.45
    propylene carbonate 153.66
    n-methylformamide 290.94
    2-pentanol 40.91
    n-pentane 4.78
    1-propoxy-2-propanol 94.22
    1-methoxy-2-propyl acetate 102.89
    2-(2-methoxypropoxy) propanol 122.32
    mesitylene 28.12
    ε-caprolactone 152.28
    p-cymene 22.72
    epichlorohydrin 286.64
    1,1,1-trichloroethane 163.46
    2-aminoethanol 148.37
    morpholine-4-carbaldehyde 369.7
    sulfolane 332.39
    2,2,4-trimethylpentane 3.73
    2-methyltetrahydrofuran 121.75
    n-hexyl acetate 61.0
    isooctane 3.34
    2-(2-butoxyethoxy)ethanol 163.62
    sec-butyl acetate 40.47
    tert-butyl acetate 58.67
    decalin 6.43
    glycerin 162.81
    diglyme 311.5
    acrylic acid 227.78
    isopropyl myristate 27.71
    n-butyric acid 171.49
    acetyl acetate 121.1
    di(2-ethylhexyl) phthalate 36.07
    ethyl propionate 71.59
    nitromethane 592.85
    1,2-diethoxyethane 133.03
    benzonitrile 125.23
    trioctyl phosphate 23.47
    1-bromopropane 87.74
    gamma-valerolactone 301.94
    n-decanol 23.82
    triethyl phosphate 38.1
    4-methyl-2-pentanol 26.13
    propionitrile 152.9
    vinylene carbonate 181.3
    1,1,2-trichlorotrifluoroethane 285.44
    DMS 95.17
    cumene 17.83
    2-octanol 16.11
    2-hexanone 52.73
    octyl acetate 35.24
    limonene 30.93
    1,2-dimethoxyethane 206.27
    ethyl orthosilicate 34.7
    tributyl phosphate 33.9
    diacetone alcohol 92.48
    N,N-dimethylaniline 49.33
    acrylonitrile 241.66
    aniline 117.89
    1,3-propanediol 153.47
    bromobenzene 111.56
    dibromomethane 200.28
    1,1,2,2-tetrachloroethane 298.85
    2-methyl-cyclohexyl acetate 45.91
    tetrabutyl urea 49.01
    diisobutyl methanol 26.69
    2-phenylethanol 73.13
    styrene 36.34
    dioctyl adipate 51.47
    dimethyl sulfate 145.77
    ethyl butyrate 64.26
    methyl lactate 98.13
    butyl lactate 50.0
    diethyl carbonate 54.53
    propanediol butyl ether 92.86
    triethyl orthoformate 49.74
    p-tert-butyltoluene 21.42
    methyl 4-tert-butylbenzoate 68.14
    morpholine 313.45
    tert-butylamine 47.87
    n-dodecanol 19.57
    dimethoxymethane 202.43
    ethylene carbonate 124.23
    cyrene 92.31
    2-ethoxyethyl acetate 86.04
    2-ethylhexyl acetate 44.86
    1,2,4-trichlorobenzene 127.48
    4-methylpyridine 184.15
    dibutyl ether 38.67
    2,6-dimethyl-4-heptanol 26.69
    DEF 165.16
    dimethyl isosorbide 166.54
    tetrachloroethylene 211.57
    eugenol 80.24
    triacetin 98.7
    span 80 89.49
    1,4-butanediol 66.53
    1,1-dichloroethane 176.78
    2-methyl-1-pentanol 44.2
    methyl formate 218.79
    2-methyl-1-butanol 54.56
    n-decane 4.45
    butyronitrile 107.87
    3,7-dimethyl-1-octanol 36.84
    1-chlorooctane 20.3
    1-chlorotetradecane 10.56
    n-nonane 3.97
    undecane 3.81
    tert-butylcyclohexane 5.53
    cyclooctane 4.66
    cyclopentanol 81.59
    tetrahydropyran 163.77
    tert-amyl methyl ether 36.67
    2,5,8-trioxanonane 243.77
    1-hexene 15.27
    2-isopropoxyethanol 86.42
    2,2,2-trifluoroethanol 140.06
    methyl butyrate 89.88

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Guava fruit (Cuba) 91770-12-6 Psidium guajava L., fam. Myrtaceae 0.1%