5-Methyl-2-pentylthiazole

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  • Identifiers

    CAS number
    86290-21-3

    Molecular formula
    C9H15NS

    SMILES
    CCCCCC1=NC=C(S1)C

    Safety labels

  • Odor profile

    Fragrance
    Green 82.7%
    Vegetable 59.81%
    Nutty 53.37%
    Roasted 52.35%
    Meaty 52.09%
    Fruity 43.61%
    Fatty 42.44%
    Earthy 39.11%
    Tropical 38.67%
    Sulfurous 36.03%

     

    Flavor
    Green 75.23%
    Earthy 48.05%
    Vegetable 43.46%
    Roasted 42.95%
    Fatty 42.53%
    Nutty 40.9%
    Pepper 39.1%
    Herbal 35.34%
    Meaty 32.68%
    Mushroom 30.17%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    6.51 (neutral)

    Molecular weight
    169.29 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Melting point expt.

    • 114.00 °C. @ 760.00 mm Hg

    Boiling point

    • 262.00 °C. @ 760.00 mm Hg

    Flash point

    • 79.59 ˚C est.

  • Synonyms

    • 5-Methyl-2-pentylthiazole
    • Thiazole, 5-methyl-2-pentyl-
    • UNII-8JH55RFD78
    • 8JH55RFD78
    • 5-METHYL-2-PENTYL-1,3-THIAZOLE
    • DTXSID601019872
    • RefChem:103127
    • DTXCID701477740
    • 86290-21-3
    • 5-methyl-2-pentyl thiazole
    • SCHEMBL2820592
    • NEZJGDWWXKETPZ-UHFFFAOYSA-N
    • AKOS006371004
    • NS00123716
    • Q27270632
    • 86290-21-3

  • Applications

    5-Methyl-2-pentylthiazole (CAS 86290-21-3) is used as a fragrance- and flavor-related chemical across several industries. In perfumery and fragrance formulations, it acts as a specialty odorant; in flavor applications, it can provide a distinct aroma note. It is also employed as an intermediate in organic synthesis, enabling the preparation of thiazole-containing building blocks for pharmaceuticals and other specialty chemicals. In cosmetics and personal care, it may serve as a fragrance ingredient; in household products and coatings/inks, it can contribute scent profiles. In industrial manufacturing, it functions as a versatile intermediate for the development of fragrance- and flavor-related formulations and other specialty chemical applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1386.42
    methanol 1000.31
    isopropanol 1028.0
    water 0.22
    ethyl acetate 1966.6
    n-propanol 1041.34
    acetone 3042.97
    n-butanol 1235.77
    acetonitrile 1138.45
    DMF 2225.6
    toluene 1203.59
    isobutanol 959.73
    1,4-dioxane 2651.48
    methyl acetate 1351.37
    THF 3530.61
    2-butanone 1961.29
    n-pentanol 933.57
    sec-butanol 900.22
    n-hexane 231.21
    ethylene glycol 147.79
    NMP 1607.57
    cyclohexane 465.89
    DMSO 1775.2
    n-butyl acetate 2361.9
    n-octanol 502.42
    chloroform 3691.79
    n-propyl acetate 1184.74
    acetic acid 1030.01
    dichloromethane 3130.32
    cyclohexanone 2817.91
    propylene glycol 299.51
    isopropyl acetate 1306.12
    DMAc 1471.26
    2-ethoxyethanol 1062.42
    isopentanol 1200.18
    n-heptane 204.97
    ethyl formate 968.64
    1,2-dichloroethane 2274.31
    n-hexanol 1392.67
    2-methoxyethanol 1541.43
    isobutyl acetate 906.99
    tetrachloromethane 668.02
    n-pentyl acetate 892.8
    transcutol 3646.54
    n-heptanol 486.13
    ethylbenzene 450.12
    MIBK 1077.5
    2-propoxyethanol 1790.35
    tert-butanol 1278.37
    MTBE 1800.87
    2-butoxyethanol 797.3
    propionic acid 677.78
    o-xylene 540.09
    formic acid 175.28
    diethyl ether 2101.08
    m-xylene 683.08
    p-xylene 611.68
    chlorobenzene 1409.88
    dimethyl carbonate 442.06
    n-octane 81.0
    formamide 271.58
    cyclopentanone 2469.88
    2-pentanone 2031.06
    anisole 841.93
    cyclopentyl methyl ether 1640.63
    gamma-butyrolactone 2014.05
    1-methoxy-2-propanol 1255.72
    pyridine 2185.27
    3-pentanone 1207.09
    furfural 1741.2
    n-dodecane 64.41
    diethylene glycol 916.14
    diisopropyl ether 593.48
    tert-amyl alcohol 994.5
    acetylacetone 1916.77
    n-hexadecane 76.82
    acetophenone 763.08
    methyl propionate 1114.54
    isopentyl acetate 1862.95
    trichloroethylene 3986.2
    n-nonanol 423.78
    cyclohexanol 1185.2
    benzyl alcohol 718.96
    2-ethylhexanol 841.25
    isooctanol 392.19
    dipropyl ether 1148.87
    1,2-dichlorobenzene 1016.24
    ethyl lactate 345.26
    propylene carbonate 1376.62
    n-methylformamide 701.38
    2-pentanol 843.81
    n-pentane 211.48
    1-propoxy-2-propanol 1396.26
    1-methoxy-2-propyl acetate 1502.72
    2-(2-methoxypropoxy) propanol 691.85
    mesitylene 401.1
    ε-caprolactone 1954.14
    p-cymene 339.8
    epichlorohydrin 2574.41
    1,1,1-trichloroethane 2201.59
    2-aminoethanol 360.37
    morpholine-4-carbaldehyde 1999.38
    sulfolane 1810.67
    2,2,4-trimethylpentane 125.95
    2-methyltetrahydrofuran 2619.26
    n-hexyl acetate 1116.86
    isooctane 111.14
    2-(2-butoxyethoxy)ethanol 1015.01
    sec-butyl acetate 832.02
    tert-butyl acetate 1297.47
    decalin 193.67
    glycerin 387.17
    diglyme 1867.11
    acrylic acid 536.4
    isopropyl myristate 404.44
    n-butyric acid 1520.51
    acetyl acetate 1046.97
    di(2-ethylhexyl) phthalate 362.14
    ethyl propionate 767.31
    nitromethane 1514.65
    1,2-diethoxyethane 1907.22
    benzonitrile 1126.36
    trioctyl phosphate 256.81
    1-bromopropane 1491.04
    gamma-valerolactone 2926.01
    n-decanol 306.93
    triethyl phosphate 353.84
    4-methyl-2-pentanol 508.92
    propionitrile 942.49
    vinylene carbonate 1179.44
    1,1,2-trichlorotrifluoroethane 1386.07
    DMS 702.75
    cumene 286.0
    2-octanol 358.92
    2-hexanone 1339.23
    octyl acetate 479.9
    limonene 641.45
    1,2-dimethoxyethane 2154.78
    ethyl orthosilicate 392.63
    tributyl phosphate 359.01
    diacetone alcohol 1014.72
    N,N-dimethylaniline 500.06
    acrylonitrile 889.58
    aniline 1033.67
    1,3-propanediol 722.59
    bromobenzene 1593.2
    dibromomethane 2187.71
    1,1,2,2-tetrachloroethane 2972.67
    2-methyl-cyclohexyl acetate 759.64
    tetrabutyl urea 443.12
    diisobutyl methanol 420.64
    2-phenylethanol 886.81
    styrene 676.23
    dioctyl adipate 501.43
    dimethyl sulfate 570.47
    ethyl butyrate 1073.12
    methyl lactate 409.94
    butyl lactate 570.85
    diethyl carbonate 600.66
    propanediol butyl ether 710.23
    triethyl orthoformate 723.07
    p-tert-butyltoluene 341.34
    methyl 4-tert-butylbenzoate 521.49
    morpholine 2889.85
    tert-butylamine 880.93
    n-dodecanol 241.51
    dimethoxymethane 1472.09
    ethylene carbonate 1100.76
    cyrene 603.69
    2-ethoxyethyl acetate 1211.15
    2-ethylhexyl acetate 1453.01
    1,2,4-trichlorobenzene 1122.1
    4-methylpyridine 2475.15
    dibutyl ether 905.77
    2,6-dimethyl-4-heptanol 420.64
    DEF 1713.97
    dimethyl isosorbide 1163.23
    tetrachloroethylene 1793.91
    eugenol 587.01
    triacetin 760.59
    span 80 699.18
    1,4-butanediol 337.01
    1,1-dichloroethane 2483.76
    2-methyl-1-pentanol 866.15
    methyl formate 621.85
    2-methyl-1-butanol 1044.86
    n-decane 114.36
    butyronitrile 1535.49
    3,7-dimethyl-1-octanol 522.52
    1-chlorooctane 433.86
    1-chlorotetradecane 177.21
    n-nonane 118.39
    undecane 82.11
    tert-butylcyclohexane 177.88
    cyclooctane 152.35
    cyclopentanol 959.46
    tetrahydropyran 3018.52
    tert-amyl methyl ether 1062.0
    2,5,8-trioxanonane 1118.71
    1-hexene 849.07
    2-isopropoxyethanol 821.28
    2,2,2-trifluoroethanol 288.22
    methyl butyrate 1172.96

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction