5-Hydroxydecanoic acid

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  • Identifiers

    CAS number
    624-00-0

    Molecular formula
    C10H20O3

    SMILES
    CCCCCC(CCCC(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Fruity 64.53%
    Cheesy 52.44%
    Fatty 52.08%
    Oily 51.6%
    Sweet 39.77%
    Dairy 39.6%
    Buttery 35.89%
    Creamy 35.3%
    Lactonic 34.71%
    Peach 34.61%

     

    Flavor
    Fatty 41.57%
    Cheese 39.25%
    Oily 37.16%
    Odorless 34.07%
    Green 31.25%
    Sour 29.62%
    Fruity 28.64%
    Sweat 28.2%
    Mild 27.44%
    Cheesy 26.36%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    6.99 (neutral)

    Molecular weight
    188.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    315°C

    Flash point

    • 160.4 ˚C est.

  • Synonyms

    • 5-HYDROXYDECANOIC ACID
    • 624-00-0
    • DTXSID10977956
    • RefChem:913445
    • DTXCID601405287
    • Decanoic acid, 5-hydroxy-
    • 5-hydroxy capric acid
    • M-14157
    • 5-Hydroxycapric acid
    • xi-5-Hydroxydecanoic acid
    • Lopac0_000628
    • BSPBio_001564
    • KBioGR_000284
    • KBioSS_000284
    • SCHEMBL316603
    • orb2567335
    • CHEMBL1373782
    • KBio2_000284
    • KBio2_002852
    • KBio2_005420
    • KBio3_000567
    • KBio3_000568
    • CHEBI:165412
    • Bio1_000355
    • Bio1_000844
    • Bio1_001333
    • Bio2_000284
    • Bio2_000764
    • HMS1791O06
    • HMS1989O06
    • HMS3402O06
    • LMFA01050032
    • AKOS006294395
    • SDCCGSBI-0050609.P002
    • IDI1_034034
    • NCGC00163138-01
    • NCGC00163138-02
    • NCGC00163138-03
    • HY-155941
    • CS-0890161
    • BRD-A96977263-001-03-7
    • 624-00-0

  • Applications

    5-Hydroxydecanoic acid (CAS 624-00-0) is used primarily as a versatile intermediate in organic synthesis, serving as a building block for hydroxy-functional monomers and esters in biobased polymers and specialty plastics, and as a precursor for the production of plasticizers and polyester derivatives. In cosmetics and personal care, it is employed as a precursor to fragrance esters and certain conditioning or moisturizing compounds. In the fragrance industry, it is considered an intermediate for fragrance ester derivatives and may form part of scent formulations. In cleaning and household products, it can be used as a precursor for surfactants or surface-active additives due to its amphiphilic character. In industrial manufacturing, it serves as a precursor for specialty chemicals, lubricants, and conditioning agents used in various formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1925.95
    methanol 3784.35
    isopropanol 1100.97
    water 4.44
    ethyl acetate 512.66
    n-propanol 989.24
    acetone 1090.22
    n-butanol 819.63
    acetonitrile 221.83
    DMF 1837.59
    toluene 32.46
    isobutanol 658.68
    1,4-dioxane 734.37
    methyl acetate 239.94
    THF 1852.72
    2-butanone 336.8
    n-pentanol 532.16
    sec-butanol 500.62
    n-hexane 31.24
    ethylene glycol 541.96
    NMP 976.02
    cyclohexane 20.64
    DMSO 3553.16
    n-butyl acetate 364.45
    n-octanol 174.71
    chloroform 110.51
    n-propyl acetate 352.96
    acetic acid 1334.09
    dichloromethane 120.54
    cyclohexanone 700.73
    propylene glycol 705.03
    isopropyl acetate 423.62
    DMAc 750.79
    2-ethoxyethanol 973.07
    isopentanol 706.31
    n-heptane 13.88
    ethyl formate 290.94
    1,2-dichloroethane 154.59
    n-hexanol 483.71
    2-methoxyethanol 2033.7
    isobutyl acetate 232.12
    tetrachloromethane 23.74
    n-pentyl acetate 203.82
    transcutol 2369.35
    n-heptanol 194.75
    ethylbenzene 34.06
    MIBK 402.24
    2-propoxyethanol 880.87
    tert-butanol 1356.92
    MTBE 380.69
    2-butoxyethanol 434.39
    propionic acid 634.69
    o-xylene 44.25
    formic acid 709.22
    diethyl ether 254.56
    m-xylene 58.84
    p-xylene 48.95
    chlorobenzene 57.41
    dimethyl carbonate 121.73
    n-octane 6.4
    formamide 800.05
    cyclopentanone 976.05
    2-pentanone 584.11
    anisole 132.03
    cyclopentyl methyl ether 581.35
    gamma-butyrolactone 1055.67
    1-methoxy-2-propanol 1518.73
    pyridine 207.19
    3-pentanone 211.32
    furfural 604.76
    n-dodecane 5.55
    diethylene glycol 773.14
    diisopropyl ether 116.49
    tert-amyl alcohol 639.3
    acetylacetone 684.69
    n-hexadecane 6.24
    acetophenone 158.6
    methyl propionate 322.13
    isopentyl acetate 327.7
    trichloroethylene 230.68
    n-nonanol 148.33
    cyclohexanol 480.0
    benzyl alcohol 176.77
    2-ethylhexanol 204.19
    isooctanol 156.74
    dipropyl ether 194.83
    1,2-dichlorobenzene 68.96
    ethyl lactate 193.78
    propylene carbonate 456.91
    n-methylformamide 884.77
    2-pentanol 469.3
    n-pentane 15.5
    1-propoxy-2-propanol 641.05
    1-methoxy-2-propyl acetate 417.57
    2-(2-methoxypropoxy) propanol 349.37
    mesitylene 52.74
    ε-caprolactone 578.47
    p-cymene 35.58
    epichlorohydrin 755.9
    1,1,1-trichloroethane 85.48
    2-aminoethanol 1073.66
    morpholine-4-carbaldehyde 979.18
    sulfolane 1402.58
    2,2,4-trimethylpentane 12.74
    2-methyltetrahydrofuran 800.47
    n-hexyl acetate 289.75
    isooctane 15.71
    2-(2-butoxyethoxy)ethanol 594.49
    sec-butyl acetate 216.21
    tert-butyl acetate 455.37
    decalin 16.19
    glycerin 897.06
    diglyme 955.39
    acrylic acid 459.1
    isopropyl myristate 95.13
    n-butyric acid 1109.08
    acetyl acetate 252.6
    di(2-ethylhexyl) phthalate 107.45
    ethyl propionate 241.94
    nitromethane 1276.23
    1,2-diethoxyethane 404.3
    benzonitrile 142.15
    trioctyl phosphate 89.02
    1-bromopropane 65.22
    gamma-valerolactone 1213.04
    n-decanol 105.8
    triethyl phosphate 91.38
    4-methyl-2-pentanol 283.49
    propionitrile 183.96
    vinylene carbonate 322.23
    1,1,2-trichlorotrifluoroethane 599.0
    DMS 182.15
    cumene 37.17
    2-octanol 118.97
    2-hexanone 364.13
    octyl acetate 125.89
    limonene 64.24
    1,2-dimethoxyethane 1102.1
    ethyl orthosilicate 93.33
    tributyl phosphate 114.42
    diacetone alcohol 741.83
    N,N-dimethylaniline 108.23
    acrylonitrile 222.43
    aniline 131.47
    1,3-propanediol 1329.43
    bromobenzene 44.81
    dibromomethane 77.0
    1,1,2,2-tetrachloroethane 228.51
    2-methyl-cyclohexyl acetate 178.17
    tetrabutyl urea 145.52
    diisobutyl methanol 113.62
    2-phenylethanol 183.07
    styrene 37.51
    dioctyl adipate 162.48
    dimethyl sulfate 254.76
    ethyl butyrate 217.16
    methyl lactate 309.31
    butyl lactate 243.75
    diethyl carbonate 115.25
    propanediol butyl ether 534.63
    triethyl orthoformate 149.54
    p-tert-butyltoluene 39.42
    methyl 4-tert-butylbenzoate 204.2
    morpholine 1179.21
    tert-butylamine 523.72
    n-dodecanol 73.98
    dimethoxymethane 816.45
    ethylene carbonate 308.46
    cyrene 300.9
    2-ethoxyethyl acetate 284.52
    2-ethylhexyl acetate 208.04
    1,2,4-trichlorobenzene 91.44
    4-methylpyridine 211.0
    dibutyl ether 150.33
    2,6-dimethyl-4-heptanol 113.62
    DEF 600.58
    dimethyl isosorbide 508.29
    tetrachloroethylene 166.8
    eugenol 212.7
    triacetin 287.59
    span 80 344.6
    1,4-butanediol 484.72
    1,1-dichloroethane 98.29
    2-methyl-1-pentanol 381.71
    methyl formate 448.49
    2-methyl-1-butanol 478.27
    n-decane 9.83
    butyronitrile 276.79
    3,7-dimethyl-1-octanol 176.03
    1-chlorooctane 51.84
    1-chlorotetradecane 18.44
    n-nonane 9.25
    undecane 7.0
    tert-butylcyclohexane 18.63
    cyclooctane 8.67
    cyclopentanol 690.52
    tetrahydropyran 608.45
    tert-amyl methyl ether 243.12
    2,5,8-trioxanonane 608.4
    1-hexene 105.07
    2-isopropoxyethanol 588.19
    2,2,2-trifluoroethanol 275.06
    methyl butyrate 373.02

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction