5-Ethyl-4-methyl-2-octylthiazole

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  • Identifiers

    CAS number
    192998-89-3

    Molecular formula
    C14H25NS

    SMILES
    CCCCCCCCC1=NC(=C(S1)CC)C

    Safety labels

  • Odor profile

    Fragrance
    Green 60.84%
    Roasted 52.35%
    Meaty 51.54%
    Nutty 49.35%
    Fatty 45.85%
    Vegetable 45.44%
    Earthy 36.21%
    Burnt 31.99%
    Fruity 31.59%
    Savory 31.4%

     

    Flavor
    Green 50.37%
    Herbal 37.11%
    Earthy 35.77%
    Fatty 34.56%
    Pepper 34.17%
    Roasted 30.04%
    Musty 26.03%
    Nutty 25.28%
    Mushroom 24.58%
    Vegetable 24.55%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    6.1

    pKa est.
    7.69 (neutral)

    Molecular weight
    239.42 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    314°C

    Flash point

    • 104.6 ˚C est.

  • Synonyms

    • 5-Ethyl-4-methyl-2-octylthiazole
    • 192998-89-3
    • RefChem:302978
    • 5-ethyl-4-methyl-2-octyl-1,3-thiazole
    • CHEBI:230225
    • KABDBXXFTIHONZ-UHFFFAOYSA-N
    • DTXSID301301894
    • 5-ethyl-4-methyl-2-octyl-thiazole
    • 192998-89-3

  • Applications

    5-Ethyl-4-methyl-2-octylthiazole, 192998-89-3, is a thiazole derivative that is commonly evaluated for use as a fragrance odorant in perfumery and cosmetic/personal care products; it may also serve as a fragrance component or odor fixative in household cleaners. It has potential as an aroma-active compound in flavor formulations, under controlled conditions. In industrial manufacturing, it can be used as an intermediate in the synthesis of thiazole-based materials. In coatings and inks, it may be encountered as a specialty fragrance additive or carrier in select formulations. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1521.13
    methanol 898.17
    isopropanol 1516.73
    water 0.03
    ethyl acetate 4381.24
    n-propanol 1655.59
    acetone 6017.04
    n-butanol 1850.99
    acetonitrile 1985.12
    DMF 4067.78
    toluene 3226.49
    isobutanol 1582.68
    1,4-dioxane 6364.89
    methyl acetate 2969.88
    THF 8093.41
    2-butanone 5057.24
    n-pentanol 1388.85
    sec-butanol 1721.58
    n-hexane 737.18
    ethylene glycol 61.23
    NMP 3429.72
    cyclohexane 2064.01
    DMSO 2682.76
    n-butyl acetate 5328.89
    n-octanol 714.11
    chloroform 6870.29
    n-propyl acetate 3178.1
    acetic acid 878.32
    dichloromethane 6797.06
    cyclohexanone 9177.96
    propylene glycol 173.26
    isopropyl acetate 3284.37
    DMAc 3331.71
    2-ethoxyethanol 1459.83
    isopentanol 1993.56
    n-heptane 541.06
    ethyl formate 1517.81
    1,2-dichloroethane 5518.73
    n-hexanol 2036.18
    2-methoxyethanol 1836.6
    isobutyl acetate 2221.38
    tetrachloromethane 1665.73
    n-pentyl acetate 2677.97
    transcutol 4924.75
    n-heptanol 732.07
    ethylbenzene 1232.76
    MIBK 2656.91
    2-propoxyethanol 2534.33
    tert-butanol 1976.75
    MTBE 5074.45
    2-butoxyethanol 1209.84
    propionic acid 910.57
    o-xylene 1417.83
    formic acid 83.47
    diethyl ether 6558.38
    m-xylene 1628.28
    p-xylene 1702.96
    chlorobenzene 3304.74
    dimethyl carbonate 793.5
    n-octane 203.52
    formamide 199.8
    cyclopentanone 6338.41
    2-pentanone 4900.97
    anisole 2011.38
    cyclopentyl methyl ether 4995.18
    gamma-butyrolactone 4509.39
    1-methoxy-2-propanol 1634.48
    pyridine 5190.81
    3-pentanone 3779.46
    furfural 2775.94
    n-dodecane 119.44
    diethylene glycol 713.77
    diisopropyl ether 1789.34
    tert-amyl alcohol 1823.2
    acetylacetone 3800.15
    n-hexadecane 152.22
    acetophenone 1749.43
    methyl propionate 2682.14
    isopentyl acetate 4309.65
    trichloroethylene 7580.7
    n-nonanol 658.58
    cyclohexanol 2774.6
    benzyl alcohol 1207.61
    2-ethylhexanol 1503.92
    isooctanol 704.49
    dipropyl ether 3197.9
    1,2-dichlorobenzene 2538.75
    ethyl lactate 546.6
    propylene carbonate 2495.08
    n-methylformamide 959.31
    2-pentanol 1599.04
    n-pentane 602.19
    1-propoxy-2-propanol 2126.29
    1-methoxy-2-propyl acetate 3040.82
    2-(2-methoxypropoxy) propanol 1027.67
    mesitylene 1089.39
    ε-caprolactone 5344.42
    p-cymene 781.96
    epichlorohydrin 5880.23
    1,1,1-trichloroethane 5740.27
    2-aminoethanol 249.6
    morpholine-4-carbaldehyde 3410.25
    sulfolane 4181.12
    2,2,4-trimethylpentane 287.4
    2-methyltetrahydrofuran 7451.46
    n-hexyl acetate 2684.38
    isooctane 233.02
    2-(2-butoxyethoxy)ethanol 1487.44
    sec-butyl acetate 2225.54
    tert-butyl acetate 3298.37
    decalin 566.77
    glycerin 217.13
    diglyme 3146.14
    acrylic acid 542.71
    isopropyl myristate 971.37
    n-butyric acid 2317.27
    acetyl acetate 2079.48
    di(2-ethylhexyl) phthalate 674.31
    ethyl propionate 2249.08
    nitromethane 1948.93
    1,2-diethoxyethane 4738.53
    benzonitrile 2114.85
    trioctyl phosphate 500.1
    1-bromopropane 4470.23
    gamma-valerolactone 5650.34
    n-decanol 478.56
    triethyl phosphate 776.79
    4-methyl-2-pentanol 933.0
    propionitrile 2141.49
    vinylene carbonate 1884.77
    1,1,2-trichlorotrifluoroethane 2078.15
    DMS 1525.14
    cumene 718.37
    2-octanol 638.26
    2-hexanone 3355.1
    octyl acetate 1118.27
    limonene 1586.75
    1,2-dimethoxyethane 4282.64
    ethyl orthosilicate 842.72
    tributyl phosphate 719.78
    diacetone alcohol 1795.41
    N,N-dimethylaniline 1173.47
    acrylonitrile 1669.22
    aniline 2159.36
    1,3-propanediol 669.48
    bromobenzene 4041.26
    dibromomethane 5064.29
    1,1,2,2-tetrachloroethane 6273.74
    2-methyl-cyclohexyl acetate 1748.44
    tetrabutyl urea 1001.27
    diisobutyl methanol 762.06
    2-phenylethanol 1439.75
    styrene 1852.03
    dioctyl adipate 1117.1
    dimethyl sulfate 1055.44
    ethyl butyrate 2763.02
    methyl lactate 538.14
    butyl lactate 1089.7
    diethyl carbonate 1315.09
    propanediol butyl ether 780.2
    triethyl orthoformate 1648.13
    p-tert-butyltoluene 748.08
    methyl 4-tert-butylbenzoate 1167.89
    morpholine 6407.93
    tert-butylamine 1532.13
    n-dodecanol 373.57
    dimethoxymethane 3060.97
    ethylene carbonate 2023.98
    cyrene 1018.32
    2-ethoxyethyl acetate 2893.28
    2-ethylhexyl acetate 3691.21
    1,2,4-trichlorobenzene 2600.75
    4-methylpyridine 6008.88
    dibutyl ether 2351.34
    2,6-dimethyl-4-heptanol 762.06
    DEF 4344.63
    dimethyl isosorbide 2186.63
    tetrachloroethylene 3925.74
    eugenol 1031.3
    triacetin 1562.2
    span 80 1062.17
    1,4-butanediol 285.09
    1,1-dichloroethane 5869.72
    2-methyl-1-pentanol 1484.6
    methyl formate 746.75
    2-methyl-1-butanol 1791.96
    n-decane 239.58
    butyronitrile 3152.95
    3,7-dimethyl-1-octanol 866.21
    1-chlorooctane 971.34
    1-chlorotetradecane 362.73
    n-nonane 246.88
    undecane 161.26
    tert-butylcyclohexane 435.18
    cyclooctane 533.23
    cyclopentanol 2044.68
    tetrahydropyran 9786.71
    tert-amyl methyl ether 2977.77
    2,5,8-trioxanonane 1812.09
    1-hexene 2455.19
    2-isopropoxyethanol 1211.05
    2,2,2-trifluoroethanol 262.5
    methyl butyrate 3309.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction