5-Dodecanol

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  • Identifiers

    CAS number
    10203-33-5

    Molecular formula
    C12H26O

    SMILES
    CCCCCCCC(CCCC)O

    Safety labels

  • Odor profile

    Fragrance
    Oily 73.24%
    Fatty 58.13%
    Floral 54.31%
    Fruity 51.94%
    Waxy 51.16%
    Herbal 50.46%
    Earthy 48.06%
    Citrus 47.05%
    Green 46.61%
    Mushroom 44.73%

     

    Flavor
    Floral 53.06%
    Fresh 47.94%
    Citrus 47.21%
    Waxy 46.32%
    Fatty 44.96%
    Mushroom 40.16%
    Green 38.83%
    Fat 38.45%
    Herbal 36.92%
    Orange 35.81%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    4.8

    pKa est.
    8.42 (weak base)

    Molecular weight
    186.33 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    242°C

    Flash point

    • 106.89 ˚C est.

  • Synonyms

    • 5-DODECANOL
    • Dodecan-5-ol
    • 10203-33-5
    • 5-hydroxydodecane
    • EINECS 233-503-0
    • NSC158520
    • AI3-35262
    • SCHEMBL258642
    • SCHEMBL4579307
    • SCHEMBL4882433
    • SCHEMBL8974845
    • SCHEMBL21694358
    • CHEBI:195406
    • DTXSID901030176
    • SBB059912
    • AKOS006281271
    • NSC 158520
    • NSC-158520
    • NS00044517
    • ST51046180
    • H39159
    • 10203-33-5

  • Applications

    5-Dodecanol (CAS 10203-33-5) is a long-chain fatty alcohol primarily used as a chemical intermediate and a functional ingredient in fragrance and personal care products. In the fragrance and flavor sector, it can serve as a precursor for ester synthesis and as a solvent or fixative component. In cosmetics and personal care, it acts as a lipophilic solvent and conditioning agent, or is used to form esters for emollients. In household and industrial cleaners, it serves as a solvent or co-solvent and as a feedstock for surfactant production. It may also be used as a component in polymer and coating formulations where it functions as a processing aid or lubricating additive. Its exact use depends on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8371.53
    methanol 4373.03
    isopropanol 12353.58
    water 0.02
    ethyl acetate 8511.8
    n-propanol 9153.21
    acetone 12601.23
    n-butanol 9891.22
    acetonitrile 4298.38
    DMF 4889.99
    toluene 2428.59
    isobutanol 7950.72
    1,4-dioxane 8048.71
    methyl acetate 4548.05
    THF 16343.16
    2-butanone 9001.99
    n-pentanol 6021.52
    sec-butanol 9698.43
    n-hexane 9504.56
    ethylene glycol 221.21
    NMP 2748.07
    cyclohexane 8245.32
    DMSO 6114.83
    n-butyl acetate 12256.12
    n-octanol 2716.32
    chloroform 8460.1
    n-propyl acetate 7019.08
    acetic acid 1949.55
    dichloromethane 7646.25
    cyclohexanone 11296.43
    propylene glycol 772.08
    isopropyl acetate 6104.87
    DMAc 2610.95
    2-ethoxyethanol 3634.96
    isopentanol 8699.69
    n-heptane 6038.07
    ethyl formate 3041.9
    1,2-dichloroethane 6683.28
    n-hexanol 9005.88
    2-methoxyethanol 5373.68
    isobutyl acetate 3977.54
    tetrachloromethane 2249.54
    n-pentyl acetate 4876.9
    transcutol 10069.36
    n-heptanol 3188.16
    ethylbenzene 1592.24
    MIBK 5264.0
    2-propoxyethanol 6802.78
    tert-butanol 14320.25
    MTBE 15130.17
    2-butoxyethanol 3685.0
    propionic acid 2632.73
    o-xylene 1347.45
    formic acid 174.0
    diethyl ether 15472.08
    m-xylene 1578.4
    p-xylene 2001.17
    chlorobenzene 2591.98
    dimethyl carbonate 614.46
    n-octane 1403.72
    formamide 335.71
    cyclopentanone 8646.01
    2-pentanone 10427.11
    anisole 2106.26
    cyclopentyl methyl ether 8834.53
    gamma-butyrolactone 5747.92
    1-methoxy-2-propanol 5583.05
    pyridine 5880.88
    3-pentanone 5074.92
    furfural 2969.1
    n-dodecane 495.02
    diethylene glycol 1735.42
    diisopropyl ether 5262.02
    tert-amyl alcohol 9617.27
    acetylacetone 4552.53
    n-hexadecane 589.93
    acetophenone 1683.39
    methyl propionate 3836.27
    isopentyl acetate 9006.86
    trichloroethylene 7634.45
    n-nonanol 2299.48
    cyclohexanol 8122.07
    benzyl alcohol 1465.45
    2-ethylhexanol 6536.44
    isooctanol 2832.07
    dipropyl ether 14938.33
    1,2-dichlorobenzene 2034.38
    ethyl lactate 1243.34
    propylene carbonate 3149.68
    n-methylformamide 1896.16
    2-pentanol 8478.29
    n-pentane 4799.62
    1-propoxy-2-propanol 7746.78
    1-methoxy-2-propyl acetate 4577.27
    2-(2-methoxypropoxy) propanol 1713.29
    mesitylene 1208.22
    ε-caprolactone 6960.04
    p-cymene 1478.17
    epichlorohydrin 6900.79
    1,1,1-trichloroethane 6776.22
    2-aminoethanol 1032.27
    morpholine-4-carbaldehyde 3258.56
    sulfolane 5214.35
    2,2,4-trimethylpentane 1171.12
    2-methyltetrahydrofuran 13883.71
    n-hexyl acetate 5187.53
    isooctane 1176.7
    2-(2-butoxyethoxy)ethanol 3084.84
    sec-butyl acetate 4682.46
    tert-butyl acetate 5948.18
    decalin 1697.2
    glycerin 676.7
    diglyme 5847.49
    acrylic acid 1143.01
    isopropyl myristate 1673.65
    n-butyric acid 7722.56
    acetyl acetate 2438.78
    di(2-ethylhexyl) phthalate 812.48
    ethyl propionate 4825.13
    nitromethane 3098.15
    1,2-diethoxyethane 9073.17
    benzonitrile 2444.45
    trioctyl phosphate 862.67
    1-bromopropane 9673.68
    gamma-valerolactone 7739.6
    n-decanol 1586.38
    triethyl phosphate 1348.66
    4-methyl-2-pentanol 4108.93
    propionitrile 5699.61
    vinylene carbonate 2032.25
    1,1,2-trichlorotrifluoroethane 3109.27
    DMS 1455.69
    cumene 1078.78
    2-octanol 2491.56
    2-hexanone 7646.55
    octyl acetate 1777.16
    limonene 3503.42
    1,2-dimethoxyethane 9845.89
    ethyl orthosilicate 1636.56
    tributyl phosphate 1159.24
    diacetone alcohol 4238.47
    N,N-dimethylaniline 1365.05
    acrylonitrile 3587.59
    aniline 2497.37
    1,3-propanediol 2711.85
    bromobenzene 2902.26
    dibromomethane 7469.23
    1,1,2,2-tetrachloroethane 7220.62
    2-methyl-cyclohexyl acetate 2883.97
    tetrabutyl urea 1425.79
    diisobutyl methanol 3470.21
    2-phenylethanol 2041.39
    styrene 2052.51
    dioctyl adipate 1771.07
    dimethyl sulfate 808.76
    ethyl butyrate 7409.53
    methyl lactate 939.48
    butyl lactate 2441.76
    diethyl carbonate 2810.82
    propanediol butyl ether 2191.96
    triethyl orthoformate 4084.11
    p-tert-butyltoluene 1434.41
    methyl 4-tert-butylbenzoate 1408.51
    morpholine 11352.63
    tert-butylamine 11861.71
    n-dodecanol 1172.29
    dimethoxymethane 4252.7
    ethylene carbonate 2617.13
    cyrene 1017.53
    2-ethoxyethyl acetate 3529.44
    2-ethylhexyl acetate 7045.12
    1,2,4-trichlorobenzene 2006.97
    4-methylpyridine 5954.37
    dibutyl ether 9285.95
    2,6-dimethyl-4-heptanol 3470.21
    DEF 6330.37
    dimethyl isosorbide 2578.67
    tetrachloroethylene 4732.67
    eugenol 1179.33
    triacetin 1994.73
    span 80 2035.55
    1,4-butanediol 873.29
    1,1-dichloroethane 9138.74
    2-methyl-1-pentanol 4734.19
    methyl formate 1086.5
    2-methyl-1-butanol 6861.12
    n-decane 1181.85
    butyronitrile 9497.37
    3,7-dimethyl-1-octanol 3206.88
    1-chlorooctane 2857.3
    1-chlorotetradecane 853.99
    n-nonane 1454.37
    undecane 721.06
    tert-butylcyclohexane 1626.46
    cyclooctane 2084.69
    cyclopentanol 6796.08
    tetrahydropyran 20017.25
    tert-amyl methyl ether 7500.54
    2,5,8-trioxanonane 2708.94
    1-hexene 15023.77
    2-isopropoxyethanol 3172.37
    2,2,2-trifluoroethanol 334.65
    methyl butyrate 7115.36

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction