5-(1-Pyrrolidinylmethyl)-2-furanmethanol

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  • Identifiers

    CAS number
    61481-02-5

    Molecular formula
    C10H15NO2

    SMILES
    C1CCN(C1)CC2=CC=C(O2)CO

    Safety labels

  • Odor profile

    Fragrance
    Fishy 44.45%
    Nutty 35.49%
    Roasted 31.99%
    Animal 29.2%
    Odorless 28.91%
    Cheesy 28.52%
    Popcorn 26.54%
    Sweet 24.61%
    Meaty 23.58%
    Caramellic 23.2%

     

    Flavor
    Bitter 47.7%
    Roasted 36.1%
    Fatty 33.9%
    Coffee 31.86%
    Earthy 24.53%
    Fruity 24.5%
    Mushroom 24.31%
    Musty 23.25%
    Waxy 23.07%
    Meaty 22.62%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    0.5

    pKa est.
    7.25 (neutral)

    Molecular weight
    181.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    315°C

    Flash point

    • 141.86 ˚C est.

  • Synonyms

    • 5-(1-Pyrrolidinylmethyl)-2-furanmethanol
    • 61481-02-5
    • [5-(pyrrolidin-1-ylmethyl)furan-2-yl]methanol
    • (5-(pyrrolidin-1-ylmethyl)furan-2-yl)methanol
    • RefChem:299270
    • {5-[(Pyrrolidin-1-yl)methyl]furan-2-yl}methanol
    • [5-[(Pyrrolidin-1-yl)methyl]furan-2-yl]methanol
    • 2-Furanmethanol, 5-(1-pyrrolidinylmethyl)-
    • H7777TV5CE
    • SCHEMBL28811140
    • DTXSID80586190
    • CHEBI:173515
    • POLAFJCRVYXYDM-UHFFFAOYSA-N
    • 5-hydroxymethylfurfuryl-pyrrolidine
    • AKOS000320880
    • 1[5'-(hydroxymethyl)furfuryl]pyrrolidine
    • 1-[5'-(Hydroxymethyl)furfuryl]pyrrolidine
    • CS-0354974
    • [5-(pyrrolidin-1-ylmethyl)uran-2-yl]methanol
    • Z1198158679
    • 61481-02-5

  • Applications

    5-(1-Pyrrolidinylmethyl)-2-furanmethanol (CAS 61481-02-5) is a synthetic intermediate and functional building block for complex organic molecules. In practice, it is commonly used as an intermediate in pharmaceutical synthesis and in the preparation of heterocyclic and amine-containing compounds; it provides a versatile scaffold for subsequent functionalization. The compound is also evaluated for cosmetic and personal-care applications as a fragrance intermediate or odorant component in formulations, and can serve as a building block for functional polymers and plastics. In coatings and inks, it may act as a reactive intermediate or precursor for specialty polymer systems. The substance is also studied as a starting point for agrochemicals or other functional agents, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 455.89
    methanol 999.36
    isopropanol 173.22
    water 26.49
    ethyl acetate 82.73
    n-propanol 285.58
    acetone 110.47
    n-butanol 212.4
    acetonitrile 76.53
    DMF 364.4
    toluene 25.64
    isobutanol 164.82
    1,4-dioxane 197.42
    methyl acetate 81.48
    THF 198.48
    2-butanone 71.53
    n-pentanol 107.54
    sec-butanol 113.85
    n-hexane 1.71
    ethylene glycol 441.43
    NMP 178.91
    cyclohexane 6.64
    DMSO 553.7
    n-butyl acetate 57.34
    n-octanol 31.83
    chloroform 353.46
    n-propyl acetate 55.73
    acetic acid 647.84
    dichloromethane 262.33
    cyclohexanone 136.72
    propylene glycol 388.79
    isopropyl acetate 45.23
    DMAc 254.44
    2-ethoxyethanol 303.99
    isopentanol 138.79
    n-heptane 2.4
    ethyl formate 138.64
    1,2-dichloroethane 138.04
    n-hexanol 82.87
    2-methoxyethanol 605.05
    isobutyl acetate 45.01
    tetrachloromethane 34.99
    n-pentyl acetate 29.06
    transcutol 580.77
    n-heptanol 37.87
    ethylbenzene 14.33
    MIBK 41.9
    2-propoxyethanol 215.65
    tert-butanol 144.84
    MTBE 42.45
    2-butoxyethanol 108.98
    propionic acid 248.26
    o-xylene 24.25
    formic acid 656.17
    diethyl ether 34.84
    m-xylene 26.07
    p-xylene 22.64
    chlorobenzene 64.83
    dimethyl carbonate 45.28
    n-octane 1.28
    formamide 538.19
    cyclopentanone 153.28
    2-pentanone 55.84
    anisole 47.71
    cyclopentyl methyl ether 68.55
    gamma-butyrolactone 232.66
    1-methoxy-2-propanol 302.7
    pyridine 155.68
    3-pentanone 37.31
    furfural 296.09
    n-dodecane 1.52
    diethylene glycol 329.49
    diisopropyl ether 10.3
    tert-amyl alcohol 98.67
    acetylacetone 79.52
    n-hexadecane 1.7
    acetophenone 61.29
    methyl propionate 73.82
    isopentyl acetate 55.09
    trichloroethylene 342.34
    n-nonanol 29.29
    cyclohexanol 120.99
    benzyl alcohol 94.2
    2-ethylhexanol 38.1
    isooctanol 31.12
    dipropyl ether 23.58
    1,2-dichlorobenzene 67.78
    ethyl lactate 73.57
    propylene carbonate 150.82
    n-methylformamide 314.31
    2-pentanol 70.5
    n-pentane 2.47
    1-propoxy-2-propanol 121.33
    1-methoxy-2-propyl acetate 78.24
    2-(2-methoxypropoxy) propanol 109.33
    mesitylene 17.06
    ε-caprolactone 135.66
    p-cymene 15.6
    epichlorohydrin 234.96
    1,1,1-trichloroethane 83.89
    2-aminoethanol 518.97
    morpholine-4-carbaldehyde 220.54
    sulfolane 244.86
    2,2,4-trimethylpentane 3.45
    2-methyltetrahydrofuran 108.58
    n-hexyl acetate 40.96
    isooctane 2.4
    2-(2-butoxyethoxy)ethanol 153.34
    sec-butyl acetate 34.41
    tert-butyl acetate 43.02
    decalin 3.6
    glycerin 543.93
    diglyme 252.0
    acrylic acid 305.33
    isopropyl myristate 17.43
    n-butyric acid 306.35
    acetyl acetate 68.21
    di(2-ethylhexyl) phthalate 36.4
    ethyl propionate 41.91
    nitromethane 438.15
    1,2-diethoxyethane 69.23
    benzonitrile 78.51
    trioctyl phosphate 21.46
    1-bromopropane 44.31
    gamma-valerolactone 256.47
    n-decanol 21.97
    triethyl phosphate 31.02
    4-methyl-2-pentanol 42.27
    propionitrile 76.39
    vinylene carbonate 172.26
    1,1,2-trichlorotrifluoroethane 366.01
    DMS 50.94
    cumene 13.84
    2-octanol 19.49
    2-hexanone 39.13
    octyl acetate 24.38
    limonene 20.92
    1,2-dimethoxyethane 206.14
    ethyl orthosilicate 29.69
    tributyl phosphate 27.12
    diacetone alcohol 87.81
    N,N-dimethylaniline 37.77
    acrylonitrile 136.26
    aniline 92.55
    1,3-propanediol 488.72
    bromobenzene 51.79
    dibromomethane 129.12
    1,1,2,2-tetrachloroethane 257.76
    2-methyl-cyclohexyl acetate 45.84
    tetrabutyl urea 34.46
    diisobutyl methanol 21.66
    2-phenylethanol 75.8
    styrene 18.81
    dioctyl adipate 36.27
    dimethyl sulfate 81.54
    ethyl butyrate 41.98
    methyl lactate 118.59
    butyl lactate 54.48
    diethyl carbonate 35.67
    propanediol butyl ether 132.73
    triethyl orthoformate 38.7
    p-tert-butyltoluene 14.84
    methyl 4-tert-butylbenzoate 62.83
    morpholine 264.71
    tert-butylamine 62.62
    n-dodecanol 16.82
    dimethoxymethane 133.72
    ethylene carbonate 136.31
    cyrene 105.4
    2-ethoxyethyl acetate 57.94
    2-ethylhexyl acetate 39.0
    1,2,4-trichlorobenzene 86.89
    4-methylpyridine 102.65
    dibutyl ether 19.13
    2,6-dimethyl-4-heptanol 21.66
    DEF 94.69
    dimethyl isosorbide 119.63
    tetrachloroethylene 200.49
    eugenol 75.31
    triacetin 67.62
    span 80 86.78
    1,4-butanediol 193.21
    1,1-dichloroethane 103.54
    2-methyl-1-pentanol 80.65
    methyl formate 217.92
    2-methyl-1-butanol 121.12
    n-decane 2.21
    butyronitrile 76.71
    3,7-dimethyl-1-octanol 34.43
    1-chlorooctane 10.91
    1-chlorotetradecane 5.34
    n-nonane 1.82
    undecane 1.8
    tert-butylcyclohexane 3.25
    cyclooctane 2.44
    cyclopentanol 126.34
    tetrahydropyran 113.35
    tert-amyl methyl ether 35.38
    2,5,8-trioxanonane 182.85
    1-hexene 8.88
    2-isopropoxyethanol 148.8
    2,2,2-trifluoroethanol 255.18
    methyl butyrate 68.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction