4,8-Cyclododecadien-1-one

Overview IFRA Request a quote

  • Identifiers

    CAS number
    15229-79-5

    Molecular formula
    C12H18O

    SMILES
    C1CC=CCCC=CCCC(=O)C1

    Safety labels

  • Odor profile

    Fragrance
    Musk 73.52%
    Powdery 51.82%
    Animal 49.34%
    Floral 36.89%
    Natural 36.89%
    Fruity 36.1%
    Amber 35.64%
    Dry 34.56%
    Warm 33.08%
    Balsamic 31.22%

     

    Flavor
    Minty 27.47%
    Animal 24.03%
    Mint 22.28%
    Shrimp 22.28%
    Ammoniacal 22.23%
    Camphor 21.32%
    Spice 20.23%
    Alkaline 19.77%
    Terpentine 19.39%
    Basil 17.93%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.8

    pKa est.
    8.72 (weak base)

    Molecular weight
    178.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    260°C

    Flash point

    • 102.95 ˚C est.

  • Synonyms

    • 4,8-Cyclododecadien-1-one
    • 15229-79-5
    • DTXSID90345018
    • Cyclododeca-4,8-dien-1-one, (E,E)-
    • RefChem:96793
    • DTXCID50296092
    • 604-843-0
    • AZSAUMXEXMBZBS-WSTKVMPZSA-N
    • cyclododeca-4,8-dien-1-one
    • cyclododeca-4,8-dienone
    • SCHEMBL812725
    • 15229-79-5

  • Applications

    4,8-Cyclododecadien-1-one (CAS 15229-79-5) is primarily regarded as an odorant and fragrance-chemical intermediate in the perfumery industry, with potential use as a building block for aroma compounds. Real-world applications include: as a fragrance component in perfumery/fragrance formulations; as an intermediate in the synthesis of other aroma compounds; as a fragrance ingredient or odorant in cosmetics/personal care formulations; as a fragrance additive in coatings/inks and household products to impart a specific scent; and as a potential building block in polymers/plastics formulations where macrocyclic enone structures are relevant. Usage is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 500.2
    methanol 403.64
    isopropanol 471.69
    water 0.12
    ethyl acetate 745.7
    n-propanol 518.94
    acetone 1094.13
    n-butanol 439.77
    acetonitrile 716.99
    DMF 1232.54
    toluene 888.2
    isobutanol 389.84
    1,4-dioxane 1098.11
    methyl acetate 685.75
    THF 1622.13
    2-butanone 944.14
    n-pentanol 314.38
    sec-butanol 475.1
    n-hexane 220.91
    ethylene glycol 93.87
    NMP 1205.09
    cyclohexane 367.58
    DMSO 1860.87
    n-butyl acetate 620.17
    n-octanol 269.76
    chloroform 2608.57
    n-propyl acetate 547.77
    acetic acid 470.53
    dichloromethane 2517.76
    cyclohexanone 1396.85
    propylene glycol 176.04
    isopropyl acetate 434.51
    DMAc 860.31
    2-ethoxyethanol 361.76
    isopentanol 380.8
    n-heptane 154.41
    ethyl formate 475.12
    1,2-dichloroethane 1435.94
    n-hexanol 376.74
    2-methoxyethanol 577.5
    isobutyl acetate 326.83
    tetrachloromethane 410.62
    n-pentyl acetate 443.02
    transcutol 2321.58
    n-heptanol 206.86
    ethylbenzene 394.63
    MIBK 439.14
    2-propoxyethanol 475.65
    tert-butanol 500.76
    MTBE 452.65
    2-butoxyethanol 349.29
    propionic acid 569.49
    o-xylene 401.58
    formic acid 98.72
    diethyl ether 677.47
    m-xylene 469.08
    p-xylene 424.73
    chlorobenzene 997.79
    dimethyl carbonate 275.89
    n-octane 56.59
    formamide 217.5
    cyclopentanone 1676.03
    2-pentanone 772.32
    anisole 585.46
    cyclopentyl methyl ether 896.31
    gamma-butyrolactone 1709.97
    1-methoxy-2-propanol 520.12
    pyridine 1521.24
    3-pentanone 660.55
    furfural 1283.68
    n-dodecane 40.35
    diethylene glycol 315.55
    diisopropyl ether 223.27
    tert-amyl alcohol 418.74
    acetylacetone 768.47
    n-hexadecane 47.16
    acetophenone 562.49
    methyl propionate 608.15
    isopentyl acetate 481.29
    trichloroethylene 2594.19
    n-nonanol 229.38
    cyclohexanol 594.37
    benzyl alcohol 424.01
    2-ethylhexanol 273.23
    isooctanol 188.55
    dipropyl ether 473.56
    1,2-dichlorobenzene 797.01
    ethyl lactate 221.8
    propylene carbonate 914.3
    n-methylformamide 569.1
    2-pentanol 362.85
    n-pentane 164.21
    1-propoxy-2-propanol 428.41
    1-methoxy-2-propyl acetate 461.19
    2-(2-methoxypropoxy) propanol 386.25
    mesitylene 277.13
    ε-caprolactone 1008.05
    p-cymene 216.26
    epichlorohydrin 1583.67
    1,1,1-trichloroethane 1239.7
    2-aminoethanol 222.78
    morpholine-4-carbaldehyde 948.56
    sulfolane 1886.45
    2,2,4-trimethylpentane 63.7
    2-methyltetrahydrofuran 1291.31
    n-hexyl acetate 639.04
    isooctane 56.6
    2-(2-butoxyethoxy)ethanol 566.49
    sec-butyl acetate 341.5
    tert-butyl acetate 423.0
    decalin 138.78
    glycerin 222.43
    diglyme 1016.97
    acrylic acid 506.85
    isopropyl myristate 236.49
    n-butyric acid 716.79
    acetyl acetate 439.23
    di(2-ethylhexyl) phthalate 204.12
    ethyl propionate 479.02
    nitromethane 895.41
    1,2-diethoxyethane 755.61
    benzonitrile 754.44
    trioctyl phosphate 157.88
    1-bromopropane 917.37
    gamma-valerolactone 1415.24
    n-decanol 169.41
    triethyl phosphate 214.39
    4-methyl-2-pentanol 206.27
    propionitrile 650.03
    vinylene carbonate 799.44
    1,1,2-trichlorotrifluoroethane 852.96
    DMS 476.07
    cumene 234.54
    2-octanol 175.86
    2-hexanone 581.08
    octyl acetate 289.68
    limonene 319.09
    1,2-dimethoxyethane 743.04
    ethyl orthosilicate 205.83
    tributyl phosphate 208.32
    diacetone alcohol 429.99
    N,N-dimethylaniline 368.73
    acrylonitrile 825.83
    aniline 735.13
    1,3-propanediol 315.18
    bromobenzene 1215.65
    dibromomethane 1818.2
    1,1,2,2-tetrachloroethane 1911.72
    2-methyl-cyclohexyl acetate 341.99
    tetrabutyl urea 277.7
    diisobutyl methanol 191.19
    2-phenylethanol 350.79
    styrene 561.48
    dioctyl adipate 338.65
    dimethyl sulfate 472.66
    ethyl butyrate 470.64
    methyl lactate 277.19
    butyl lactate 335.47
    diethyl carbonate 315.14
    propanediol butyl ether 411.64
    triethyl orthoformate 309.4
    p-tert-butyltoluene 193.47
    methyl 4-tert-butylbenzoate 415.91
    morpholine 1132.24
    tert-butylamine 370.62
    n-dodecanol 131.47
    dimethoxymethane 618.66
    ethylene carbonate 673.83
    cyrene 351.77
    2-ethoxyethyl acetate 531.36
    2-ethylhexyl acetate 393.56
    1,2,4-trichlorobenzene 898.3
    4-methylpyridine 1289.93
    dibutyl ether 511.63
    2,6-dimethyl-4-heptanol 191.19
    DEF 737.45
    dimethyl isosorbide 633.78
    tetrachloroethylene 1241.26
    eugenol 363.4
    triacetin 574.48
    span 80 382.84
    1,4-butanediol 134.84
    1,1-dichloroethane 1391.15
    2-methyl-1-pentanol 285.21
    methyl formate 449.17
    2-methyl-1-butanol 378.26
    n-decane 72.06
    butyronitrile 638.7
    3,7-dimethyl-1-octanol 276.87
    1-chlorooctane 288.85
    1-chlorotetradecane 106.34
    n-nonane 78.75
    undecane 51.59
    tert-butylcyclohexane 110.87
    cyclooctane 126.12
    cyclopentanol 648.51
    tetrahydropyran 1339.81
    tert-amyl methyl ether 359.76
    2,5,8-trioxanonane 626.38
    1-hexene 492.13
    2-isopropoxyethanol 294.44
    2,2,2-trifluoroethanol 181.58
    methyl butyrate 657.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction