4,5-Dihydro-2-methyl-3-furanthiol

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  • Identifiers

    CAS number
    26486-13-5

    Molecular formula
    C5H8OS

    SMILES
    CC1=C(CCO1)S

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Meaty 86.41%
    Sulfurous 84.14%
    Roasted 76.06%
    Savory 52.47%
    Onion 46.06%
    Beefy 41.07%
    Cooked 39.93%
    Burnt 37.82%
    Coffee 32.49%
    Garlic 31.75%

     

    Flavor
    Roasted 41.84%
    Sulfurous 34.73%
    Caramel 34.28%
    Meaty 32.67%
    Onion 32.18%
    Nutty 30.64%
    Vegetable 30.24%
    Sulfury 27.41%
    Potato 27.21%
    Roast 26.34%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    7.47 (neutral)

    Molecular weight
    116.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    154°C

    Flash point

    • 35.78 ˚C est.

    Solubility expt.

    • Insoluble in water
    • Soluble (in ethanol)

  • Synonyms

    • 26486-13-5
    • 2-methyl-4,5-dihydrofuran-3-thiol
    • 2-Methyl-4,5-dihydrofurane-3-thiol
    • 3-Furanthiol, 4,5-dihydro-2-methyl-
    • 4,5-Dihydro-2-methyl-3-furanthiol
    • 5-methyl-2,3-dihydrofuran-4-thiol
    • 4,5-Dihydro-3-mercapto-2-methylfuran
    • 3-Mercapto-2-methyl-4,5-dihydrofuran
    • 4,5-Dihydro-2-methyl-3-mercaptofuran
    • 3(2H)-Furanthione, dihydro-2-methyl-
    • 58O51Z0A2I
    • FEMA NO. 4683
    • DTXSID00335581
    • 2-methyl-4,5-dihydro-3-furanthiol
    • Dihydro-2-methyl-3(2H)-furanthione
    • UNII-58O51Z0A2I
    • 2-Methyl-4,5(2H)-Furanthiol-3
    • METHYL DIHYDROFURANTHIOL
    • SCHEMBL2968795
    • DTXCID50286670
    • CHEBI:193952
    • 5-methyl-2,3-dihydrouran-4-thiol
    • 3-Furanthiol, 4,5-dihydro-2-methyl
    • AKOS006329456
    • 4,5-Dihydro-2-methyl-3-furanthiol, 9CI
    • DB-003295
    • NS00122223
    • Q27261604
    • 639-121-4

  • Applications

    4,5-Dihydro-2-methyl-3-furanthiol (CAS 26486-13-5) is typically used as an aroma/fragrance ingredient and odorant, contributing sulfur-containing notes to fragrance and flavor formulations to add depth and character. In cosmetics and personal care, it may be included to enhance fragrance performance and longevity. It is also regarded as a synthetic intermediate for sulfur-bearing aroma compounds used in industrial fragrance chemistry. Additionally, use in food and beverage flavor systems may be considered where permitted by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1368.69
    methanol 2140.14
    isopropanol 972.32
    water 204.02
    ethyl acetate 594.43
    n-propanol 945.06
    acetone 1146.14
    n-butanol 653.0
    acetonitrile 1312.87
    DMF 1668.83
    toluene 265.68
    isobutanol 622.59
    1,4-dioxane 1727.66
    methyl acetate 992.12
    THF 867.89
    2-butanone 816.07
    n-pentanol 428.12
    sec-butanol 822.46
    n-hexane 29.08
    ethylene glycol 831.23
    NMP 821.67
    cyclohexane 55.61
    DMSO 1247.11
    n-butyl acetate 106.07
    n-octanol 144.15
    chloroform 1923.14
    n-propyl acetate 189.25
    acetic acid 1240.33
    dichloromethane 1538.65
    cyclohexanone 531.81
    propylene glycol 823.43
    isopropyl acetate 256.67
    DMAc 1497.06
    2-ethoxyethanol 1012.41
    isopentanol 410.79
    n-heptane 23.49
    ethyl formate 454.67
    1,2-dichloroethane 714.43
    n-hexanol 206.22
    2-methoxyethanol 1843.25
    isobutyl acetate 105.95
    tetrachloromethane 445.07
    n-pentyl acetate 121.42
    transcutol 1206.87
    n-heptanol 146.94
    ethylbenzene 103.71
    MIBK 194.0
    2-propoxyethanol 491.34
    tert-butanol 756.93
    MTBE 421.93
    2-butoxyethanol 344.74
    propionic acid 774.18
    o-xylene 181.02
    formic acid 1117.11
    diethyl ether 575.4
    m-xylene 142.6
    p-xylene 166.25
    chlorobenzene 339.23
    dimethyl carbonate 303.26
    n-octane 12.54
    formamide 1693.06
    cyclopentanone 590.67
    2-pentanone 413.86
    anisole 388.35
    cyclopentyl methyl ether 329.03
    gamma-butyrolactone 684.08
    1-methoxy-2-propanol 1001.65
    pyridine 1013.9
    3-pentanone 396.81
    furfural 878.52
    n-dodecane 12.37
    diethylene glycol 635.03
    diisopropyl ether 97.44
    tert-amyl alcohol 595.37
    acetylacetone 516.81
    n-hexadecane 13.71
    acetophenone 318.03
    methyl propionate 538.48
    isopentyl acetate 97.19
    trichloroethylene 1297.57
    n-nonanol 131.39
    cyclohexanol 425.76
    benzyl alcohol 384.68
    2-ethylhexanol 98.36
    isooctanol 107.82
    dipropyl ether 117.58
    1,2-dichlorobenzene 291.96
    ethyl lactate 156.44
    propylene carbonate 282.72
    n-methylformamide 1154.66
    2-pentanol 390.29
    n-pentane 52.63
    1-propoxy-2-propanol 268.61
    1-methoxy-2-propyl acetate 201.23
    2-(2-methoxypropoxy) propanol 277.27
    mesitylene 77.92
    ε-caprolactone 446.47
    p-cymene 54.49
    epichlorohydrin 934.88
    1,1,1-trichloroethane 815.71
    2-aminoethanol 1150.6
    morpholine-4-carbaldehyde 1455.15
    sulfolane 533.71
    2,2,4-trimethylpentane 24.81
    2-methyltetrahydrofuran 622.67
    n-hexyl acetate 167.97
    isooctane 13.55
    2-(2-butoxyethoxy)ethanol 388.86
    sec-butyl acetate 124.76
    tert-butyl acetate 211.83
    decalin 25.56
    glycerin 938.77
    diglyme 767.28
    acrylic acid 771.64
    isopropyl myristate 74.03
    n-butyric acid 528.87
    acetyl acetate 351.85
    di(2-ethylhexyl) phthalate 81.55
    ethyl propionate 187.38
    nitromethane 2049.18
    1,2-diethoxyethane 307.15
    benzonitrile 365.17
    trioctyl phosphate 50.61
    1-bromopropane 351.96
    gamma-valerolactone 1097.62
    n-decanol 90.81
    triethyl phosphate 77.31
    4-methyl-2-pentanol 153.07
    propionitrile 719.47
    vinylene carbonate 362.58
    1,1,2-trichlorotrifluoroethane 923.58
    DMS 210.28
    cumene 69.08
    2-octanol 98.96
    2-hexanone 222.88
    octyl acetate 94.29
    limonene 76.87
    1,2-dimethoxyethane 1039.74
    ethyl orthosilicate 77.84
    tributyl phosphate 58.96
    diacetone alcohol 334.25
    N,N-dimethylaniline 235.58
    acrylonitrile 929.03
    aniline 534.24
    1,3-propanediol 1051.84
    bromobenzene 305.35
    dibromomethane 812.97
    1,1,2,2-tetrachloroethane 1017.58
    2-methyl-cyclohexyl acetate 96.13
    tetrabutyl urea 83.54
    diisobutyl methanol 62.34
    2-phenylethanol 221.26
    styrene 154.42
    dioctyl adipate 105.63
    dimethyl sulfate 406.23
    ethyl butyrate 107.55
    methyl lactate 341.2
    butyl lactate 112.56
    diethyl carbonate 89.5
    propanediol butyl ether 293.12
    triethyl orthoformate 96.03
    p-tert-butyltoluene 56.91
    methyl 4-tert-butylbenzoate 195.79
    morpholine 1634.57
    tert-butylamine 429.49
    n-dodecanol 67.54
    dimethoxymethane 926.67
    ethylene carbonate 289.55
    cyrene 288.02
    2-ethoxyethyl acetate 248.2
    2-ethylhexyl acetate 72.96
    1,2,4-trichlorobenzene 407.61
    4-methylpyridine 793.0
    dibutyl ether 110.51
    2,6-dimethyl-4-heptanol 62.34
    DEF 590.95
    dimethyl isosorbide 329.73
    tetrachloroethylene 810.72
    eugenol 243.91
    triacetin 244.17
    span 80 210.43
    1,4-butanediol 488.45
    1,1-dichloroethane 913.01
    2-methyl-1-pentanol 272.98
    methyl formate 725.42
    2-methyl-1-butanol 454.74
    n-decane 20.36
    butyronitrile 504.27
    3,7-dimethyl-1-octanol 115.27
    1-chlorooctane 71.85
    1-chlorotetradecane 32.09
    n-nonane 18.05
    undecane 15.32
    tert-butylcyclohexane 23.22
    cyclooctane 17.62
    cyclopentanol 486.61
    tetrahydropyran 717.63
    tert-amyl methyl ether 284.36
    2,5,8-trioxanonane 547.0
    1-hexene 104.03
    2-isopropoxyethanol 547.27
    2,2,2-trifluoroethanol 686.31
    methyl butyrate 230.43

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction