4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    155601-30-2

    Molecular formula
    C5H12N4O5S

    SMILES
    C1=NN(C(=C1N)N)CCO.OS(=O)(=O)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 68.41%
    Fishy 32.62%
    Savory 20.49%
    Meaty 19.12%
    Nutty 18.04%
    Animal 18.01%
    Ripe 17.59%
    Cooked 17.09%
    Burnt 16.91%
    Cheesy 16.89%

     

    Flavor
    Bitter 59.89%
    Odorless 48.75%
    Mild 33.59%
    Roasted 28.26%
    Sweet-like 24.0%
    Bland 23.05%
    Bread crust 21.45%
    Cooked beef juice 21.29%
    Scallion 21.12%
    Roasted peanuts 20.57%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    4.28 (weak acid)

    Molecular weight
    240.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    469°C

    Flash point

    • 205.28 ˚C est.

  • Synonyms

    • 155601-30-2
    • 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate
    • Colorex WP5
    • 1H-Pyrazole-1-ethanol, 4,5-diamino-, sulfate (1:1)
    • 1-Hydroxyethyl 4,5-diamino pyrazole sulfate
    • UNII-04N8KX12N6
    • 1-(2-Hydroxyethyl)-4,5-diaminopyrazole sulfate
    • 4,5-Diamino-1-(2-hydroxyethyl)-1H-pyrazole sulfate
    • 04N8KX12N6
    • 1H-Pyrazole-1-ethanol, 4,5-diamino-, sulfate (1:1) (salt)
    • DTXSID20165928
    • EC 429-300-3
    • RefChem:96425
    • DTXCID5088419
    • 4,5-diamino-1-(2-hydroxyethyl)-pyrazole sulfate
    • 1-HYDROXYETHYL 4,5-DIAMINO PYRAZOLE SULFATE [INCI]
    • 605-017-2
    • MFCD07368638
    • 4,5-Diamino-1-(2-hydroxy)ethyl pyrazole sulfate
    • 4,5-DIAMINO-1-(2-HYDROXYETHYL)PYRAZOLESULPHATE
    • C5H12N4O5S
    • 2-(4,5-diaminopyrazol-1-yl)ethanol;sulfuric acid
    • 4,5-DIAMINO-1-PYRAZOLEETHANOL SULFATE
    • 4,5-Diamino-1-(2-hydroxyethyl)pyrazolesulfate
    • 4,5-Diamino-1-(2-Hydroxyethyl) pyrazole sulfate
    • 1-(2-Hydroxyethyl)-4,5-diaminopyrazole Sulfate; 4,5-Diamino-1-(2-hydroxyethyl)-1H-pyrazole Sulfate; Jarocol AHP; Rodol HDAP; 4,5-Diamino-1H-pyrazole-1-ethanol Sulfate (1:1);
    • SCHEMBL143344
    • 2-(4,5-Diamino-1H-pyrazol-1-yl)ethan-1-ol sulfate
    • 1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate
    • 2-(4,5-diamino-1H-pyrazol-1-yl)ethan-1-ol; sulfuric acid
    • AKOS015856642
    • AB32056
    • AC-8151
    • CS-W003383
    • AS-15654
    • FD139495
    • SY021155
    • 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfat
    • EN300-213558
    • 601D302
    • F078921
    • Q27247659
    • 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfuric acid salt
    • 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfate, AldrichCPR
    • Sulfuric acid--2-(4,5-diamino-1H-pyrazol-1-yl)ethan-1-ol (1/1)
    • 155601-30-2

  • Applications

    4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate (CAS 155601-30-2) is primarily used as an organic building block in synthetic chemistry, providing a pyrazole core with amino and hydroxyethyl functionality that enables further derivatization. In industry, it is commonly evaluated as an intermediate for the synthesis of pyrazole-containing compounds in pharmaceuticals and agrochemicals, and as a precursor for specialty polymers and coatings where the hydroxyethyl group can participate in crosslinking or bonding. The compound can also function as a coordinating ligand or reactive intermediate in metal-complex formulations relevant to catalysis and electronic materials. It may also be employed in adhesive formulations where amino/hydroxy functionalities promote network formation. Applications are highly formulation-dependent and subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.36
    methanol 22.88
    isopropanol 3.72
    water 161.82
    ethyl acetate 1.04
    n-propanol 5.03
    acetone 4.04
    n-butanol 4.38
    acetonitrile 4.05
    DMF 90.48
    toluene 0.54
    isobutanol 3.38
    1,4-dioxane 13.76
    methyl acetate 1.35
    THF 13.06
    2-butanone 2.32
    n-pentanol 2.77
    sec-butanol 3.14
    n-hexane 0.11
    ethylene glycol 30.05
    NMP 90.99
    cyclohexane 0.4
    DMSO 188.91
    n-butyl acetate 0.91
    n-octanol 1.03
    chloroform 1.34
    n-propyl acetate 0.72
    acetic acid 34.3
    dichloromethane 2.97
    cyclohexanone 8.89
    propylene glycol 19.21
    isopropyl acetate 0.63
    DMAc 57.46
    2-ethoxyethanol 17.39
    isopentanol 3.09
    n-heptane 0.31
    ethyl formate 4.97
    1,2-dichloroethane 2.17
    n-hexanol 2.28
    2-methoxyethanol 46.03
    isobutyl acetate 0.47
    tetrachloromethane 0.69
    n-pentyl acetate 0.99
    transcutol 9.72
    n-heptanol 1.84
    ethylbenzene 0.32
    MIBK 1.06
    2-propoxyethanol 10.44
    tert-butanol 3.52
    MTBE 0.99
    2-butoxyethanol 7.05
    propionic acid 6.43
    o-xylene 0.93
    formic acid 155.95
    diethyl ether 0.96
    m-xylene 0.56
    p-xylene 0.64
    chlorobenzene 0.84
    dimethyl carbonate 1.71
    n-octane 0.14
    formamide 90.22
    cyclopentanone 10.97
    2-pentanone 1.61
    anisole 1.04
    cyclopentyl methyl ether 2.86
    gamma-butyrolactone 17.0
    1-methoxy-2-propanol 15.65
    pyridine 6.51
    3-pentanone 1.44
    furfural 32.81
    n-dodecane 0.09
    diethylene glycol 24.5
    diisopropyl ether 0.29
    tert-amyl alcohol 2.97
    acetylacetone 2.72
    n-hexadecane 0.1
    acetophenone 1.9
    methyl propionate 1.71
    isopentyl acetate 0.99
    trichloroethylene 2.78
    n-nonanol 1.08
    cyclohexanol 4.1
    benzyl alcohol 3.3
    2-ethylhexanol 1.31
    isooctanol 1.51
    dipropyl ether 1.02
    1,2-dichlorobenzene 1.07
    ethyl lactate 2.16
    propylene carbonate 6.32
    n-methylformamide 33.98
    2-pentanol 1.49
    n-pentane 0.16
    1-propoxy-2-propanol 4.85
    1-methoxy-2-propyl acetate 2.02
    2-(2-methoxypropoxy) propanol 4.91
    mesitylene 0.5
    ε-caprolactone 7.27
    p-cymene 0.66
    epichlorohydrin 12.37
    1,1,1-trichloroethane 0.79
    2-aminoethanol 28.41
    morpholine-4-carbaldehyde 49.41
    sulfolane 56.19
    2,2,4-trimethylpentane 0.1
    2-methyltetrahydrofuran 5.72
    n-hexyl acetate 1.02
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 7.06
    sec-butyl acetate 0.44
    tert-butyl acetate 0.78
    decalin 0.13
    glycerin 58.93
    diglyme 12.71
    acrylic acid 12.04
    isopropyl myristate 0.45
    n-butyric acid 6.75
    acetyl acetate 0.97
    di(2-ethylhexyl) phthalate 1.75
    ethyl propionate 0.71
    nitromethane 30.27
    1,2-diethoxyethane 1.61
    benzonitrile 2.87
    trioctyl phosphate 1.2
    1-bromopropane 0.78
    gamma-valerolactone 31.87
    n-decanol 0.82
    triethyl phosphate 1.26
    4-methyl-2-pentanol 0.89
    propionitrile 1.9
    vinylene carbonate 6.5
    1,1,2-trichlorotrifluoroethane 24.51
    DMS 1.2
    cumene 0.36
    2-octanol 0.91
    2-hexanone 1.01
    octyl acetate 0.74
    limonene 0.98
    1,2-dimethoxyethane 13.15
    ethyl orthosilicate 1.25
    tributyl phosphate 1.02
    diacetone alcohol 3.63
    N,N-dimethylaniline 1.41
    acrylonitrile 4.32
    aniline 2.24
    1,3-propanediol 25.35
    bromobenzene 0.6
    dibromomethane 1.44
    1,1,2,2-tetrachloroethane 2.68
    2-methyl-cyclohexyl acetate 1.32
    tetrabutyl urea 2.06
    diisobutyl methanol 0.75
    2-phenylethanol 2.66
    styrene 0.32
    dioctyl adipate 1.03
    dimethyl sulfate 7.87
    ethyl butyrate 0.99
    methyl lactate 5.66
    butyl lactate 2.37
    diethyl carbonate 0.74
    propanediol butyl ether 6.35
    triethyl orthoformate 1.24
    p-tert-butyltoluene 0.59
    methyl 4-tert-butylbenzoate 3.08
    morpholine 17.85
    tert-butylamine 1.31
    n-dodecanol 0.62
    dimethoxymethane 10.02
    ethylene carbonate 4.47
    cyrene 14.38
    2-ethoxyethyl acetate 1.78
    2-ethylhexyl acetate 0.81
    1,2,4-trichlorobenzene 1.49
    4-methylpyridine 4.39
    dibutyl ether 0.58
    2,6-dimethyl-4-heptanol 0.75
    DEF 7.39
    dimethyl isosorbide 8.31
    tetrachloroethylene 2.56
    eugenol 4.91
    triacetin 1.87
    span 80 5.35
    1,4-butanediol 12.77
    1,1-dichloroethane 0.84
    2-methyl-1-pentanol 2.23
    methyl formate 20.73
    2-methyl-1-butanol 3.26
    n-decane 0.14
    butyronitrile 2.63
    3,7-dimethyl-1-octanol 0.89
    1-chlorooctane 0.36
    1-chlorotetradecane 0.18
    n-nonane 0.13
    undecane 0.11
    tert-butylcyclohexane 0.09
    cyclooctane 0.18
    cyclopentanol 7.23
    tetrahydropyran 4.18
    tert-amyl methyl ether 1.07
    2,5,8-trioxanonane 11.0
    1-hexene 0.26
    2-isopropoxyethanol 6.14
    2,2,2-trifluoroethanol 19.75
    methyl butyrate 1.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction