4,4'-Dihydroxybenzophenone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    611-99-4

    Molecular formula
    C13H10O3

    SMILES
    C1=CC(=CC=C1C(=O)C2=CC=C(C=C2)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Phenolic 70.53%
    Sweet 51.02%
    Medicinal 45.25%
    Balsamic 43.9%
    Bitter 37.29%
    Nutty 36.73%
    Vanilla 35.88%
    Spicy 33.02%
    Aromatic 32.01%
    Fruity 31.83%

     

    Flavor
    Bitter 84.02%
    Phenolic 24.67%
    Odorless 24.22%
    Balsam 23.86%
    Mild 22.55%
    Nitrile 21.97%
    Urine 21.72%
    Very strong 21.68%
    Indole 21.34%
    Moth ball 20.89%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.7

    pKa est.
    9.35 (weak base)

    Molecular weight
    214.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    438°C

    Flash point

    • 201.52 ˚C est.

  • Synonyms

    • 4,4'-Dihydroxybenzophenone
    • 611-99-4
    • bis(4-hydroxyphenyl)methanone
    • Bis(4-hydroxyphenyl) ketone
    • Methanone, bis(4-hydroxyphenyl)-
    • HBP (ketone)
    • 4,4'-dihydoxy-benzophenone
    • Bis(p-hydroxy)benzophenone
    • p,p'-Dihydroxybenzophenone
    • 4,4'-Dihydroxydiphenyl ketone
    • Benzophenone, 4,4'-dihydroxy-
    • NSC 2831
    • 4,4'dihydroxybenzophenone
    • HZR7D31SBY
    • EINECS 210-288-1
    • BRN 1874572
    • CCRIS 9457
    • AI3-00127
    • NSC-2831
    • 4-08-00-02452 (Beilstein Handbook Reference)
    • Bis(phydroxy)benzophenone
    • p,p'Dihydroxybenzophenone
    • 4,4'Dihydoxybenzophenone
    • RefChem:506654
    • Bis(4hydroxyphenyl) ketone
    • 4,4'Dihydroxydiphenyl ketone
    • Benzophenone, 4,4'dihydroxy
    • Methanone, bis(4hydroxyphenyl)
    • Methanone, bis(4-hydroxyphenyl)-(9CI)
    • 210-288-1
    • 4,4-Dihydroxybenzophenone
    • MFCD00002358
    • Bis(4-hydroxy)benzophenone
    • 4-(4-hydroxybenzoyl)phenol
    • 4,4-DIHYDROXY BENZOPHENONE
    • 4,4'-Dihydoxybenzophenone
    • 4,4'-dihydroxy benzophenone
    • DTXSID1022425
    • Bis-(4-hydroxy-phenyl)-methanone
    • di4-hydroxyphenyl ketone
    • UNII-HZR7D31SBY
    • 4,4'-dihydroxybenzophenon
    • 4,4' dihydroxybenzophenone
    • 4,4'dihydroxy-benzophenone
    • 4,4 -Dihydroxybenzophenone
    • 4,4?-Dihydroxybenzophenone
    • 4,4`-Dihydroxybenzophenone
    • 4,4'-dihydroxy-benzophenone
    • Oprea1_287266
    • SCHEMBL18423
    • 4,4\'-Dihydroxybenzophenone
    • BIDD:ER0179
    • bis(4-hydroxyphenyl)-methanone
    • CHEMBL194859
    • DTXCID602425
    • orb2940195
    • BDBM25807
    • CHEBI:34365
    • NSC2831
    • BP_14
    • 4,4'-Dihydroxybenzophenone, 99%
    • Tox21_200550
    • 4-[(4-hydroxyphenyl)carbonyl]phenol
    • AC-348
    • AC7529
    • Compound 0627-0373 (DHBP)
    • SBB000543
    • STK668062
    • AKOS005206702
    • CS-W014942
    • DB07635
    • EBC-612355
    • FB18692
    • GS-3450
    • HY-W014226
    • MSK157037-100A
    • MSK157037-1000A
    • NCGC00248695-01
    • NCGC00258104-01
    • CAS-611-99-4
    • PD005603
    • ST041020
    • SY005681
    • DB-014392
    • D0577
    • NS00005686
    • 4,4'-Dihydroxybenzophenone, analytical standard
    • 611D994
    • F046288
    • SR-01000393027
    • 4,4 inverted exclamation mark -Dihydroxybenzophenone
    • 4,4 inverted exclamation marka-Dihydroxybenzophenone
    • Q4637052
    • SR-01000393027-1
    • 4,4'-Dihydroxybenzophenone Solution in Acetonitrile, 100ug/mL
    • 4,4'-Dihydroxybenzophenone Solution in Acetonitrile, 1000ug/mL
    • 611-99-4

  • Applications

    4,4'-Dihydroxybenzophenone (CAS 611-99-4) is primarily used as a functional diol and building block in the synthesis of polymers and coatings, serving as a diol component for polyesters and polyurethanes to enhance UV stability and weather resistance; it also acts as a UV stabilizer in coatings, paints, and films to extend service life under light exposure; owing to its two phenolic OH groups, it is used as a precursor for functionalized resin systems and adhesive formulations that can be crosslinked or tailored for specific applications; it is evaluated for UV-curable formulations and photoactive polymer systems depending on local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.26
    methanol 9.87
    isopropanol 5.57
    water 0.13
    ethyl acetate 25.85
    n-propanol 7.02
    acetone 36.98
    n-butanol 5.72
    acetonitrile 19.17
    DMF 144.16
    toluene 1.77
    isobutanol 3.99
    1,4-dioxane 46.96
    methyl acetate 44.6
    THF 123.71
    2-butanone 63.23
    n-pentanol 7.69
    sec-butanol 13.61
    n-hexane 0.07
    ethylene glycol 8.34
    NMP 66.23
    cyclohexane 0.04
    DMSO 181.14
    n-butyl acetate 21.29
    n-octanol 5.17
    chloroform 1.74
    n-propyl acetate 22.45
    acetic acid 27.34
    dichloromethane 1.36
    cyclohexanone 41.76
    propylene glycol 14.66
    isopropyl acetate 25.91
    DMAc 234.53
    2-ethoxyethanol 45.21
    isopentanol 9.03
    n-heptane 0.2
    ethyl formate 14.8
    1,2-dichloroethane 3.39
    n-hexanol 8.04
    2-methoxyethanol 64.83
    isobutyl acetate 10.73
    tetrachloromethane 0.4
    n-pentyl acetate 13.0
    transcutol 260.44
    n-heptanol 6.38
    ethylbenzene 3.08
    MIBK 23.58
    2-propoxyethanol 39.93
    tert-butanol 20.1
    MTBE 26.8
    2-butoxyethanol 26.94
    propionic acid 23.39
    o-xylene 3.39
    formic acid 23.89
    diethyl ether 9.54
    m-xylene 2.3
    p-xylene 3.49
    chlorobenzene 2.52
    dimethyl carbonate 28.66
    n-octane 0.11
    formamide 133.06
    cyclopentanone 80.67
    2-pentanone 26.82
    anisole 28.6
    cyclopentyl methyl ether 18.68
    gamma-butyrolactone 107.14
    1-methoxy-2-propanol 53.64
    pyridine 24.18
    3-pentanone 23.88
    furfural 70.27
    n-dodecane 0.21
    diethylene glycol 41.84
    diisopropyl ether 4.71
    tert-amyl alcohol 29.8
    acetylacetone 67.55
    n-hexadecane 0.26
    acetophenone 31.64
    methyl propionate 30.2
    isopentyl acetate 23.06
    trichloroethylene 11.72
    n-nonanol 5.92
    cyclohexanol 6.91
    benzyl alcohol 18.59
    2-ethylhexanol 7.91
    isooctanol 6.41
    dipropyl ether 11.8
    1,2-dichlorobenzene 5.03
    ethyl lactate 22.94
    propylene carbonate 38.61
    n-methylformamide 52.49
    2-pentanol 6.81
    n-pentane 0.03
    1-propoxy-2-propanol 34.04
    1-methoxy-2-propyl acetate 47.1
    2-(2-methoxypropoxy) propanol 55.01
    mesitylene 2.39
    ε-caprolactone 42.9
    p-cymene 4.24
    epichlorohydrin 77.89
    1,1,1-trichloroethane 3.02
    2-aminoethanol 15.89
    morpholine-4-carbaldehyde 104.25
    sulfolane 126.1
    2,2,4-trimethylpentane 0.48
    2-methyltetrahydrofuran 41.02
    n-hexyl acetate 17.77
    isooctane 0.26
    2-(2-butoxyethoxy)ethanol 61.94
    sec-butyl acetate 20.84
    tert-butyl acetate 40.91
    decalin 0.34
    glycerin 39.62
    diglyme 125.44
    acrylic acid 27.9
    isopropyl myristate 9.59
    n-butyric acid 19.45
    acetyl acetate 22.05
    di(2-ethylhexyl) phthalate 10.8
    ethyl propionate 23.59
    nitromethane 116.12
    1,2-diethoxyethane 46.28
    benzonitrile 13.6
    trioctyl phosphate 6.99
    1-bromopropane 0.91
    gamma-valerolactone 109.36
    n-decanol 4.79
    triethyl phosphate 17.75
    4-methyl-2-pentanol 7.72
    propionitrile 13.71
    vinylene carbonate 29.64
    1,1,2-trichlorotrifluoroethane 66.93
    DMS 31.19
    cumene 3.27
    2-octanol 4.24
    2-hexanone 24.0
    octyl acetate 10.57
    limonene 5.27
    1,2-dimethoxyethane 86.64
    ethyl orthosilicate 16.91
    tributyl phosphate 10.12
    diacetone alcohol 62.73
    N,N-dimethylaniline 18.62
    acrylonitrile 25.89
    aniline 9.11
    1,3-propanediol 19.81
    bromobenzene 1.63
    dibromomethane 0.52
    1,1,2,2-tetrachloroethane 12.73
    2-methyl-cyclohexyl acetate 19.47
    tetrabutyl urea 14.85
    diisobutyl methanol 8.18
    2-phenylethanol 17.56
    styrene 3.31
    dioctyl adipate 19.15
    dimethyl sulfate 64.65
    ethyl butyrate 22.46
    methyl lactate 37.2
    butyl lactate 18.23
    diethyl carbonate 18.09
    propanediol butyl ether 28.2
    triethyl orthoformate 22.28
    p-tert-butyltoluene 4.58
    methyl 4-tert-butylbenzoate 31.44
    morpholine 59.93
    tert-butylamine 7.23
    n-dodecanol 3.71
    dimethoxymethane 61.58
    ethylene carbonate 21.34
    cyrene 45.43
    2-ethoxyethyl acetate 33.7
    2-ethylhexyl acetate 16.6
    1,2,4-trichlorobenzene 8.7
    4-methylpyridine 18.01
    dibutyl ether 10.62
    2,6-dimethyl-4-heptanol 8.18
    DEF 43.21
    dimethyl isosorbide 74.49
    tetrachloroethylene 6.37
    eugenol 32.68
    triacetin 38.37
    span 80 29.37
    1,4-butanediol 8.91
    1,1-dichloroethane 1.45
    2-methyl-1-pentanol 12.37
    methyl formate 34.83
    2-methyl-1-butanol 9.18
    n-decane 0.3
    butyronitrile 8.8
    3,7-dimethyl-1-octanol 7.79
    1-chlorooctane 2.0
    1-chlorotetradecane 1.14
    n-nonane 0.2
    undecane 0.25
    tert-butylcyclohexane 0.5
    cyclooctane 0.04
    cyclopentanol 8.39
    tetrahydropyran 17.37
    tert-amyl methyl ether 27.22
    2,5,8-trioxanonane 91.66
    1-hexene 0.75
    2-isopropoxyethanol 34.98
    2,2,2-trifluoroethanol 18.44
    methyl butyrate 26.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction