4-Terpineol, (-)-

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    20126-76-5

    Molecular formula
    C10H18O

    SMILES
    CC1=CC[C@](CC1)(C(C)C)O

    Safety labels

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 1180.0
    • Carbowax: 1600.0

  • Odor profile

    Fragrance
    Herbal 72.13%
    Sweet 67.96%
    Earthy 62.74%
    Green 62.74%
    Woody 56.1%
    Spicy 55.53%
    Mint 53.88%
    Camphoreous 52.46%
    Citrus 51.98%
    Musty 51.34%

     

    Flavor
    Sweet 62.68%
    Woody 61.99%
    Herbal 50.98%
    Musty 38.55%
    Spicy 37.88%
    Herb 36.98%
    Minty 36.54%
    Earthy 31.54%
    Camphor 29.73%
    Floral 29.59%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    10.9 (weak base)

    Molecular weight
    154.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    206°C

    Flash point

    • 84.45 ˚C est.

  • Synonyms

    • (-)-Terpinen-4-ol
    • 20126-76-5
    • (-)-4-Terpineol
    • 3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-, (1R)-
    • 4-Terpinenol, L-
    • (R)-Terpinen-4-ol
    • (R)-4-Carvomenthenol
    • 4-Terpineol, (-)-
    • p-Menth-1-en-4-ol, (R)-(-)-
    • 4-Carvomenthenol, (-)-
    • (1R)-4-methyl-1-propan-2-ylcyclohex-3-en-1-ol
    • (R)-(-)-p-Menth-1-en-4-ol
    • (R)-p-Menth-1-en-4-ol
    • 3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-, (R)-
    • 8VI196VS5T
    • P-Meth-1-en-4-OL
    • MFCD00167108
    • (R)-4-Methyl-1-(1-methylethyl)-3-cyclohexen-1-ol
    • (1R)-4-Methyl-1-(1-methylethyl)-3-cyclohexen-1-ol
    • (R)-1-Isopropyl-4-methyl-3-cyclohexen-1-ol
    • DTXSID101033857
    • L-4-terpineneol
    • L-4-terpineol
    • L-terpinen-4-ol
    • UNII-8VI196VS5T
    • (-)-1-Isopropyl-4-methyl-3-cyclohexen-1-ol
    • 1-Isopropyl-4-methyl-3-cyclohexen-1-ol, (R)-
    • CHEMBL2287509
    • SCHEMBL13180470
    • CHEBI:211664
    • DTXCID101518629
    • HY-N7927
    • AKOS028109360
    • (-)-Terpinen-4-ol, analytical standard
    • AS-10641
    • (R)-1-Isopropyl-4-methylcyclohex-3-enol
    • CS-0138818
    • NS00113751
    • (R)-1-isopropyl-4-methylcyclohex-3-en-1-ol
    • D91315
    • EN300-7413298
    • (1R)-4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol
    • Q27271081
    • 3-Cyclohexen-1-ol,4-methyl-1-(1-methylethyl)-,(1R)-
    • (-)-Terpinen-4-ol, >=95.0% (sum of enantiomers, GC)
    • 629-645-1

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 509.05
    methanol 394.58
    isopropanol 477.32
    water 1.22
    ethyl acetate 319.52
    n-propanol 424.89
    acetone 191.25
    n-butanol 457.23
    acetonitrile 292.48
    DMF 186.34
    toluene 247.76
    isobutanol 276.57
    1,4-dioxane 721.98
    methyl acetate 275.22
    THF 715.7
    2-butanone 302.14
    n-pentanol 265.23
    sec-butanol 380.65
    n-hexane 72.67
    ethylene glycol 47.1
    NMP 126.14
    cyclohexane 120.01
    DMSO 146.21
    n-butyl acetate 327.22
    n-octanol 246.54
    chloroform 717.4
    n-propyl acetate 155.64
    acetic acid 151.05
    dichloromethane 469.93
    cyclohexanone 299.42
    propylene glycol 109.95
    isopropyl acetate 200.31
    DMAc 217.28
    2-ethoxyethanol 257.81
    isopentanol 353.68
    n-heptane 99.76
    ethyl formate 166.48
    1,2-dichloroethane 211.02
    n-hexanol 482.64
    2-methoxyethanol 409.01
    isobutyl acetate 126.9
    tetrachloromethane 168.13
    n-pentyl acetate 208.68
    transcutol 872.39
    n-heptanol 247.92
    ethylbenzene 141.15
    MIBK 168.91
    2-propoxyethanol 464.64
    tert-butanol 532.21
    MTBE 430.33
    2-butoxyethanol 296.21
    propionic acid 158.98
    o-xylene 152.6
    formic acid 48.54
    diethyl ether 417.5
    m-xylene 156.33
    p-xylene 183.4
    chlorobenzene 195.3
    dimethyl carbonate 56.12
    n-octane 41.42
    formamide 87.28
    cyclopentanone 255.73
    2-pentanone 239.42
    anisole 227.95
    cyclopentyl methyl ether 251.37
    gamma-butyrolactone 229.86
    1-methoxy-2-propanol 359.68
    pyridine 414.25
    3-pentanone 164.69
    furfural 235.27
    n-dodecane 32.89
    diethylene glycol 225.35
    diisopropyl ether 133.18
    tert-amyl alcohol 389.36
    acetylacetone 174.59
    n-hexadecane 36.93
    acetophenone 158.86
    methyl propionate 173.59
    isopentyl acetate 282.87
    trichloroethylene 378.69
    n-nonanol 218.25
    cyclohexanol 251.09
    benzyl alcohol 163.94
    2-ethylhexanol 260.16
    isooctanol 192.26
    dipropyl ether 295.33
    1,2-dichlorobenzene 160.39
    ethyl lactate 72.3
    propylene carbonate 162.62
    n-methylformamide 122.81
    2-pentanol 297.69
    n-pentane 88.58
    1-propoxy-2-propanol 386.47
    1-methoxy-2-propyl acetate 244.79
    2-(2-methoxypropoxy) propanol 273.67
    mesitylene 104.49
    ε-caprolactone 281.95
    p-cymene 128.15
    epichlorohydrin 313.45
    1,1,1-trichloroethane 310.02
    2-aminoethanol 153.93
    morpholine-4-carbaldehyde 289.91
    sulfolane 160.78
    2,2,4-trimethylpentane 46.49
    2-methyltetrahydrofuran 477.37
    n-hexyl acetate 295.5
    isooctane 44.3
    2-(2-butoxyethoxy)ethanol 375.17
    sec-butyl acetate 136.74
    tert-butyl acetate 203.42
    decalin 57.55
    glycerin 111.3
    diglyme 552.44
    acrylic acid 100.5
    isopropyl myristate 127.57
    n-butyric acid 294.91
    acetyl acetate 149.48
    di(2-ethylhexyl) phthalate 115.69
    ethyl propionate 140.22
    nitromethane 188.0
    1,2-diethoxyethane 390.28
    benzonitrile 238.22
    trioctyl phosphate 85.58
    1-bromopropane 272.76
    gamma-valerolactone 361.69
    n-decanol 162.19
    triethyl phosphate 92.66
    4-methyl-2-pentanol 188.11
    propionitrile 336.74
    vinylene carbonate 165.68
    1,1,2-trichlorotrifluoroethane 186.25
    DMS 129.65
    cumene 110.88
    2-octanol 172.64
    2-hexanone 188.49
    octyl acetate 156.91
    limonene 170.25
    1,2-dimethoxyethane 426.44
    ethyl orthosilicate 104.85
    tributyl phosphate 95.39
    diacetone alcohol 203.57
    N,N-dimethylaniline 157.34
    acrylonitrile 253.49
    aniline 235.49
    1,3-propanediol 257.6
    bromobenzene 205.54
    dibromomethane 364.0
    1,1,2,2-tetrachloroethane 323.06
    2-methyl-cyclohexyl acetate 175.37
    tetrabutyl urea 111.88
    diisobutyl methanol 156.06
    2-phenylethanol 229.8
    styrene 153.55
    dioctyl adipate 145.01
    dimethyl sulfate 62.06
    ethyl butyrate 211.79
    methyl lactate 86.59
    butyl lactate 137.58
    diethyl carbonate 132.44
    propanediol butyl ether 241.09
    triethyl orthoformate 161.73
    p-tert-butyltoluene 134.01
    methyl 4-tert-butylbenzoate 190.59
    morpholine 737.26
    tert-butylamine 389.73
    n-dodecanol 127.04
    dimethoxymethane 212.82
    ethylene carbonate 148.55
    cyrene 138.64
    2-ethoxyethyl acetate 253.27
    2-ethylhexyl acetate 233.64
    1,2,4-trichlorobenzene 181.53
    4-methylpyridine 386.5
    dibutyl ether 245.85
    2,6-dimethyl-4-heptanol 156.06
    DEF 186.63
    dimethyl isosorbide 311.38
    tetrachloroethylene 220.01
    eugenol 175.65
    triacetin 204.92
    span 80 243.52
    1,4-butanediol 84.24
    1,1-dichloroethane 322.29
    2-methyl-1-pentanol 227.04
    methyl formate 71.68
    2-methyl-1-butanol 296.44
    n-decane 56.62
    butyronitrile 383.79
    3,7-dimethyl-1-octanol 230.97
    1-chlorooctane 146.4
    1-chlorotetradecane 64.74
    n-nonane 53.26
    undecane 41.87
    tert-butylcyclohexane 60.93
    cyclooctane 46.35
    cyclopentanol 217.81
    tetrahydropyran 651.48
    tert-amyl methyl ether 251.75
    2,5,8-trioxanonane 394.23
    1-hexene 199.2
    2-isopropoxyethanol 196.52
    2,2,2-trifluoroethanol 48.1
    methyl butyrate 164.46

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Tea Tree (Australia) 9 68647-73-4 Melaleuca alternifolia (Maiden et Betche) Cheel, fam. Myrtaceae 13.13%