4-Phenyl-1,3-dioxolane

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  • Identifiers

    CAS number
    1075-20-3

    Molecular formula
    C9H10O2

    SMILES
    C1C(OCO1)C2=CC=CC=C2

  • Odor profile

    Fragrance
    Floral 66.66%
    Sweet 62.08%
    Rose 55.13%
    Fruity 44.46%
    Green 41.22%
    Almond 40.64%
    Earthy 39.46%
    Hyacinth 37.97%
    Honey 37.62%
    Aromatic 36.37%

     

    Flavor
    Sweet 76.0%
    Bitter 62.08%
    Woody 47.07%
    Floral 39.04%
    Herbal 29.24%
    Warm 28.07%
    Naphthalic 26.71%
    Coconut 25.34%
    Almond 24.88%
    Spicy 24.62%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    5.38 (weak acid)

    Molecular weight
    150.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    237°C

    Flash point

    • 92.25 ˚C est.

  • Synonyms

    • 4-Phenyl-1,3-dioxolane
    • 1075-20-3
    • 1,3-Dioxolane, 4-phenyl-
    • AI3-24753
    • EINECS 214-051-3
    • DTXSID00862524
    • 1,3Dioxolane, 4phenyl
    • SCHEMBL528466
    • DTXCID40811273
    • OVKDCYKVNYLEHK-UHFFFAOYSA-N
    • DB-263245
    • NS00041963
    • 214-051-3

  • Applications

    For 4-Phenyl-1,3-dioxolane (CAS 1075-20-3), it is primarily regarded as an organic intermediate and a protecting group for carbonyl compounds in organic synthesis, commonly used to shield aldehyde or ketone functionality under reaction conditions to enable subsequent steps. It also serves as a precursor or building block for acetal-containing compounds in chemical manufacturing, including routes toward pharmaceuticals and polymers/plastics. Additionally, it may function as a solvent or processing aid in specialty formulations, and can appear as an intermediate in cosmetics, coatings/inks, or cleaning formulations under appropriate regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 236.68
    methanol 198.09
    isopropanol 133.9
    water 4.92
    ethyl acetate 131.7
    n-propanol 174.23
    acetone 171.99
    n-butanol 129.31
    acetonitrile 245.13
    DMF 322.02
    toluene 92.0
    isobutanol 112.04
    1,4-dioxane 336.13
    methyl acetate 150.71
    THF 281.74
    2-butanone 136.95
    n-pentanol 91.2
    sec-butanol 107.75
    n-hexane 8.71
    ethylene glycol 148.64
    NMP 214.83
    cyclohexane 25.75
    DMSO 469.1
    n-butyl acetate 79.61
    n-octanol 60.59
    chloroform 686.55
    n-propyl acetate 94.51
    acetic acid 255.49
    dichloromethane 780.7
    cyclohexanone 185.77
    propylene glycol 127.02
    isopropyl acetate 66.89
    DMAc 236.29
    2-ethoxyethanol 192.82
    isopentanol 88.55
    n-heptane 22.41
    ethyl formate 134.35
    1,2-dichloroethane 341.37
    n-hexanol 108.22
    2-methoxyethanol 272.0
    isobutyl acetate 62.74
    tetrachloromethane 79.37
    n-pentyl acetate 51.13
    transcutol 360.4
    n-heptanol 57.98
    ethylbenzene 52.07
    MIBK 72.13
    2-propoxyethanol 180.72
    tert-butanol 131.63
    MTBE 72.12
    2-butoxyethanol 106.28
    propionic acid 179.97
    o-xylene 69.04
    formic acid 98.82
    diethyl ether 104.36
    m-xylene 65.83
    p-xylene 62.87
    chlorobenzene 137.11
    dimethyl carbonate 79.87
    n-octane 9.8
    formamide 156.97
    cyclopentanone 226.27
    2-pentanone 102.4
    anisole 123.67
    cyclopentyl methyl ether 122.08
    gamma-butyrolactone 281.3
    1-methoxy-2-propanol 176.32
    pyridine 283.77
    3-pentanone 91.65
    furfural 278.91
    n-dodecane 10.11
    diethylene glycol 179.67
    diisopropyl ether 29.95
    tert-amyl alcohol 92.04
    acetylacetone 125.1
    n-hexadecane 11.12
    acetophenone 118.68
    methyl propionate 126.4
    isopentyl acetate 69.18
    trichloroethylene 560.62
    n-nonanol 56.69
    cyclohexanol 109.91
    benzyl alcohol 113.95
    2-ethylhexanol 68.43
    isooctanol 49.02
    dipropyl ether 88.57
    1,2-dichlorobenzene 131.79
    ethyl lactate 80.35
    propylene carbonate 171.84
    n-methylformamide 191.66
    2-pentanol 71.61
    n-pentane 12.85
    1-propoxy-2-propanol 122.3
    1-methoxy-2-propyl acetate 93.54
    2-(2-methoxypropoxy) propanol 119.45
    mesitylene 44.74
    ε-caprolactone 152.0
    p-cymene 47.53
    epichlorohydrin 341.43
    1,1,1-trichloroethane 237.51
    2-aminoethanol 178.32
    morpholine-4-carbaldehyde 267.24
    sulfolane 327.85
    2,2,4-trimethylpentane 9.37
    2-methyltetrahydrofuran 180.22
    n-hexyl acetate 75.81
    isooctane 8.48
    2-(2-butoxyethoxy)ethanol 144.55
    sec-butyl acetate 55.35
    tert-butyl acetate 67.06
    decalin 15.69
    glycerin 177.53
    diglyme 289.75
    acrylic acid 187.3
    isopropyl myristate 45.03
    n-butyric acid 168.16
    acetyl acetate 89.17
    di(2-ethylhexyl) phthalate 50.55
    ethyl propionate 86.66
    nitromethane 313.02
    1,2-diethoxyethane 102.33
    benzonitrile 137.13
    trioctyl phosphate 37.22
    1-bromopropane 164.04
    gamma-valerolactone 234.64
    n-decanol 46.65
    triethyl phosphate 53.86
    4-methyl-2-pentanol 45.72
    propionitrile 181.9
    vinylene carbonate 178.37
    1,1,2-trichlorotrifluoroethane 244.6
    DMS 73.47
    cumene 42.72
    2-octanol 36.08
    2-hexanone 85.07
    octyl acetate 54.89
    limonene 60.81
    1,2-dimethoxyethane 246.82
    ethyl orthosilicate 48.84
    tributyl phosphate 40.66
    diacetone alcohol 98.19
    N,N-dimethylaniline 93.31
    acrylonitrile 241.07
    aniline 128.58
    1,3-propanediol 180.59
    bromobenzene 150.02
    dibromomethane 468.35
    1,1,2,2-tetrachloroethane 393.03
    2-methyl-cyclohexyl acetate 74.19
    tetrabutyl urea 61.65
    diisobutyl methanol 45.79
    2-phenylethanol 93.9
    styrene 67.37
    dioctyl adipate 68.07
    dimethyl sulfate 124.04
    ethyl butyrate 88.67
    methyl lactate 93.72
    butyl lactate 58.84
    diethyl carbonate 71.66
    propanediol butyl ether 99.86
    triethyl orthoformate 65.49
    p-tert-butyltoluene 43.84
    methyl 4-tert-butylbenzoate 106.1
    morpholine 303.32
    tert-butylamine 84.15
    n-dodecanol 39.8
    dimethoxymethane 195.71
    ethylene carbonate 145.03
    cyrene 125.98
    2-ethoxyethyl acetate 75.68
    2-ethylhexyl acetate 53.88
    1,2,4-trichlorobenzene 151.56
    4-methylpyridine 184.5
    dibutyl ether 61.16
    2,6-dimethyl-4-heptanol 45.79
    DEF 147.54
    dimethyl isosorbide 165.01
    tetrachloroethylene 258.01
    eugenol 106.08
    triacetin 107.41
    span 80 95.99
    1,4-butanediol 97.75
    1,1-dichloroethane 296.2
    2-methyl-1-pentanol 71.71
    methyl formate 151.59
    2-methyl-1-butanol 88.32
    n-decane 14.27
    butyronitrile 146.26
    3,7-dimethyl-1-octanol 60.41
    1-chlorooctane 47.71
    1-chlorotetradecane 25.03
    n-nonane 13.48
    undecane 11.65
    tert-butylcyclohexane 13.76
    cyclooctane 11.64
    cyclopentanol 129.71
    tetrahydropyran 205.23
    tert-amyl methyl ether 58.12
    2,5,8-trioxanonane 212.23
    1-hexene 34.27
    2-isopropoxyethanol 123.37
    2,2,2-trifluoroethanol 108.75
    methyl butyrate 113.88

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction