4'-Morpholinopropiophenone

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  • Identifiers

    CAS number
    78987-46-9

    Molecular formula
    C13H17NO2

    SMILES
    CCC(=O)C1=CC=C(C=C1)N2CCOCC2

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 43.59%
    Sweet 38.04%
    Nutty 34.71%
    Popcorn 28.78%
    Animal 28.4%
    Roasted 28.21%
    Hay 26.38%
    Vanilla 25.78%
    Powdery 25.08%
    Caramellic 24.91%

     

    Flavor
    Bitter 40.65%
    Sweet 36.9%
    Floral 33.02%
    Fruity 26.5%
    Roasted 23.08%
    Animal 21.48%
    Musty 21.21%
    Orange flower 21.17%
    Petitgrain 21.05%
    Orange blossom 20.96%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    5.71 (weak acid)

    Molecular weight
    219.28 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    363°C

    Flash point

    • 169.96 ˚C est.

  • Synonyms

    • 78987-46-9
    • 1-[4-(morpholin-4-yl)phenyl]propan-1-one
    • 1-(4-morpholin-4-ylphenyl)propan-1-one
    • 1-(4-Morpholin-4-yl-phenyl)propan-1-one
    • 4'-Morpholinopropiophenone
    • NSC108695
    • p-morpholino propiophenone
    • 1-(4-Morpholin-4-yl-phenyl)-propan-1-one
    • 1-Propanone, 1-[4-(4-morpholinyl)phenyl]-
    • SCHEMBL50003
    • DTXSID601000174
    • 1-(4-Morpholinophenyl)propan-1-one
    • AKOS000299408
    • NSC-108695
    • 1-[4-(4-morpholinyl)phenyl]-1-propanone
    • DS-008078
    • A1-03743
    • 654-073-4

  • Applications

    4'-Morpholinopropiophenone (CAS 78987-46-9) is used primarily as a UV photoinitiator for free-radical polymerization, enabling rapid curing in UV-curable coatings, inks, and adhesives; in polymer formulations it participates in initiating the polymerization of acrylate resins and related systems; it is employed in UV-curable resins for additive manufacturing and advanced plastics processing; in electronics it is applied in photoresists and coatings for PCB substrates; in industrial manufacturing it supports fast cure cycles and improves coating adhesion and properties under UV exposure.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 22.61
    methanol 34.46
    isopropanol 12.92
    water 1.42
    ethyl acetate 48.99
    n-propanol 17.64
    acetone 77.72
    n-butanol 18.78
    acetonitrile 54.1
    DMF 179.8
    toluene 23.59
    isobutanol 14.1
    1,4-dioxane 76.72
    methyl acetate 48.75
    THF 77.53
    2-butanone 60.71
    n-pentanol 16.2
    sec-butanol 12.5
    n-hexane 1.85
    ethylene glycol 21.85
    NMP 161.57
    cyclohexane 2.58
    DMSO 480.87
    n-butyl acetate 44.6
    n-octanol 4.77
    chloroform 376.08
    n-propyl acetate 34.9
    acetic acid 116.38
    dichloromethane 439.0
    cyclohexanone 91.24
    propylene glycol 15.38
    isopropyl acetate 33.12
    DMAc 234.85
    2-ethoxyethanol 67.51
    isopentanol 21.4
    n-heptane 1.06
    ethyl formate 45.3
    1,2-dichloroethane 268.78
    n-hexanol 13.54
    2-methoxyethanol 91.31
    isobutyl acetate 22.61
    tetrachloromethane 35.51
    n-pentyl acetate 17.46
    transcutol 424.91
    n-heptanol 6.44
    ethylbenzene 15.29
    MIBK 29.91
    2-propoxyethanol 53.21
    tert-butanol 22.39
    MTBE 23.83
    2-butoxyethanol 28.22
    propionic acid 46.35
    o-xylene 24.77
    formic acid 90.53
    diethyl ether 28.58
    m-xylene 20.22
    p-xylene 18.73
    chlorobenzene 75.59
    dimethyl carbonate 38.89
    n-octane 0.44
    formamide 154.94
    cyclopentanone 106.06
    2-pentanone 43.0
    anisole 50.51
    cyclopentyl methyl ether 36.4
    gamma-butyrolactone 144.61
    1-methoxy-2-propanol 55.28
    pyridine 88.2
    3-pentanone 52.15
    furfural 213.89
    n-dodecane 0.45
    diethylene glycol 78.06
    diisopropyl ether 9.62
    tert-amyl alcohol 21.15
    acetylacetone 87.37
    n-hexadecane 0.54
    acetophenone 60.77
    methyl propionate 48.64
    isopentyl acetate 42.09
    trichloroethylene 519.47
    n-nonanol 5.24
    cyclohexanol 20.66
    benzyl alcohol 41.62
    2-ethylhexanol 12.01
    isooctanol 6.73
    dipropyl ether 16.1
    1,2-dichlorobenzene 100.29
    ethyl lactate 30.3
    propylene carbonate 82.05
    n-methylformamide 79.56
    2-pentanol 11.53
    n-pentane 1.54
    1-propoxy-2-propanol 36.7
    1-methoxy-2-propyl acetate 66.71
    2-(2-methoxypropoxy) propanol 63.19
    mesitylene 14.21
    ε-caprolactone 77.23
    p-cymene 13.07
    epichlorohydrin 231.16
    1,1,1-trichloroethane 149.74
    2-aminoethanol 26.76
    morpholine-4-carbaldehyde 175.3
    sulfolane 261.43
    2,2,4-trimethylpentane 2.01
    2-methyltetrahydrofuran 49.8
    n-hexyl acetate 22.51
    isooctane 1.16
    2-(2-butoxyethoxy)ethanol 71.37
    sec-butyl acetate 25.15
    tert-butyl acetate 38.87
    decalin 3.17
    glycerin 50.05
    diglyme 170.93
    acrylic acid 66.8
    isopropyl myristate 10.63
    n-butyric acid 52.04
    acetyl acetate 60.11
    di(2-ethylhexyl) phthalate 19.9
    ethyl propionate 36.3
    nitromethane 239.33
    1,2-diethoxyethane 69.04
    benzonitrile 54.88
    trioctyl phosphate 9.97
    1-bromopropane 65.94
    gamma-valerolactone 173.15
    n-decanol 4.11
    triethyl phosphate 35.28
    4-methyl-2-pentanol 10.72
    propionitrile 36.49
    vinylene carbonate 93.16
    1,1,2-trichlorotrifluoroethane 224.89
    DMS 57.26
    cumene 12.63
    2-octanol 3.76
    2-hexanone 33.27
    octyl acetate 12.72
    limonene 16.29
    1,2-dimethoxyethane 107.58
    ethyl orthosilicate 30.83
    tributyl phosphate 19.11
    diacetone alcohol 48.0
    N,N-dimethylaniline 38.46
    acrylonitrile 63.22
    aniline 49.53
    1,3-propanediol 36.37
    bromobenzene 82.18
    dibromomethane 226.84
    1,1,2,2-tetrachloroethane 378.03
    2-methyl-cyclohexyl acetate 35.89
    tetrabutyl urea 24.57
    diisobutyl methanol 9.36
    2-phenylethanol 34.25
    styrene 22.91
    dioctyl adipate 26.84
    dimethyl sulfate 104.33
    ethyl butyrate 39.24
    methyl lactate 41.76
    butyl lactate 23.66
    diethyl carbonate 39.32
    propanediol butyl ether 27.35
    triethyl orthoformate 34.45
    p-tert-butyltoluene 11.66
    methyl 4-tert-butylbenzoate 43.73
    morpholine 77.86
    tert-butylamine 14.65
    n-dodecanol 3.53
    dimethoxymethane 76.95
    ethylene carbonate 67.55
    cyrene 70.1
    2-ethoxyethyl acetate 50.63
    2-ethylhexyl acetate 34.28
    1,2,4-trichlorobenzene 123.59
    4-methylpyridine 71.84
    dibutyl ether 12.25
    2,6-dimethyl-4-heptanol 9.36
    DEF 73.57
    dimethyl isosorbide 103.58
    tetrachloroethylene 220.21
    eugenol 46.8
    triacetin 55.45
    span 80 33.16
    1,4-butanediol 19.56
    1,1-dichloroethane 143.75
    2-methyl-1-pentanol 21.17
    methyl formate 68.88
    2-methyl-1-butanol 19.34
    n-decane 0.69
    butyronitrile 32.43
    3,7-dimethyl-1-octanol 8.99
    1-chlorooctane 4.67
    1-chlorotetradecane 2.32
    n-nonane 0.57
    undecane 0.53
    tert-butylcyclohexane 2.62
    cyclooctane 1.16
    cyclopentanol 19.16
    tetrahydropyran 40.03
    tert-amyl methyl ether 23.44
    2,5,8-trioxanonane 126.57
    1-hexene 7.8
    2-isopropoxyethanol 40.82
    2,2,2-trifluoroethanol 84.76
    methyl butyrate 44.36

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction